AU2003283055A8 - Opioid-receptor antagonists in transdermal systems having buprenorphine - Google Patents

Opioid-receptor antagonists in transdermal systems having buprenorphine

Info

Publication number
AU2003283055A8
AU2003283055A8 AU2003283055A AU2003283055A AU2003283055A8 AU 2003283055 A8 AU2003283055 A8 AU 2003283055A8 AU 2003283055 A AU2003283055 A AU 2003283055A AU 2003283055 A AU2003283055 A AU 2003283055A AU 2003283055 A8 AU2003283055 A8 AU 2003283055A8
Authority
AU
Australia
Prior art keywords
opioid
receptor antagonists
buprenorphine
transdermal systems
transdermal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003283055A
Other versions
AU2003283055A1 (en
Inventor
Heinrich Kugelmann
Johannes Bartholomaus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
Original Assignee
Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2002137057 external-priority patent/DE10237057A1/en
Priority claimed from DE2002137056 external-priority patent/DE10237056A1/en
Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH
Publication of AU2003283055A1 publication Critical patent/AU2003283055A1/en
Publication of AU2003283055A8 publication Critical patent/AU2003283055A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to opioid-receptor antagonists such as, for example, naloxone in transdermal forms of administration at least containing buprenorphine as an active principle.
AU2003283055A 2002-08-09 2003-08-08 Opioid-receptor antagonists in transdermal systems having buprenorphine Abandoned AU2003283055A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE2002137057 DE10237057A1 (en) 2002-08-09 2002-08-09 Transdermal therapeutic systems containing buprenorphine, useful in treating pain or urinary incontinence, also containing mu-, kappa- or delta-opioid receptor antagonist to reduce abuse potential
DE2002137056 DE10237056A1 (en) 2002-08-09 2002-08-09 Transdermal therapeutic systems containing buprenorphine, useful in treating pain or urinary incontinence, also containing mu-, kappa- or delta-opioid receptor antagonist to reduce abuse potential
DE10237057.5 2002-08-09
DE10237056.7 2002-08-09
PCT/EP2003/008828 WO2004014336A2 (en) 2002-08-09 2003-08-08 Opioid-receptor antagonists in transdermal systems having buprenorphine

Publications (2)

Publication Number Publication Date
AU2003283055A1 AU2003283055A1 (en) 2004-02-25
AU2003283055A8 true AU2003283055A8 (en) 2004-02-25

Family

ID=31716605

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003283055A Abandoned AU2003283055A1 (en) 2002-08-09 2003-08-08 Opioid-receptor antagonists in transdermal systems having buprenorphine

Country Status (9)

Country Link
EP (1) EP1526848B1 (en)
AT (1) ATE367155T1 (en)
AU (1) AU2003283055A1 (en)
CY (1) CY1107739T1 (en)
DE (1) DE50307717D1 (en)
DK (1) DK1526848T3 (en)
ES (1) ES2290512T3 (en)
PT (1) PT1526848E (en)
WO (1) WO2004014336A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1718258E (en) * 2004-02-23 2009-06-16 Euro Celtique Sa Abuse resistance opioid transdermal delivery device
DE102004019916A1 (en) * 2004-04-21 2005-11-17 Grünenthal GmbH Anti-abuse drug-containing patch
DE102006054731B4 (en) * 2006-11-21 2013-02-28 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system for administration of the active ingredient buprenorphine and use thereof in pain therapy
GB2447015A (en) * 2007-03-01 2008-09-03 Reckitt Benckiser Healthcare Analgesic composition comprising a specific ratio of buprenorphine and naltrexone
GB2447016A (en) * 2007-03-01 2008-09-03 Reckitt Benckiser Healthcare Buprenorphine/naloxone compositions
MX2010010512A (en) * 2008-03-26 2010-11-09 Alltranz Inc Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists.
AP4036A (en) * 2011-12-12 2017-02-22 Lohmann Therapie Syst Lts Transdermal delivery system comprising buprenorphine
EP3106153A1 (en) 2013-06-04 2016-12-21 LTS LOHMANN Therapie-Systeme AG Transdermal delivery system

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3939376C1 (en) * 1989-11-29 1991-05-08 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg, 5450 Neuwied, De
EP0914097B1 (en) * 1996-03-12 2002-01-16 Alza Corporation Composition and dosage form comprising opioid antagonist
JPH1036265A (en) * 1996-07-19 1998-02-10 Nitto Denko Corp Buprenorphine percutaneous absorption preparation
US5968547A (en) * 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
US5900420A (en) * 1997-06-19 1999-05-04 Cole; William L. Method for treating chronic fatigue syndrome and fibromyalgia with buprenorphine

Also Published As

Publication number Publication date
WO2004014336A3 (en) 2004-12-09
ES2290512T3 (en) 2008-02-16
AU2003283055A1 (en) 2004-02-25
EP1526848B1 (en) 2007-07-18
DK1526848T3 (en) 2007-10-22
EP1526848A2 (en) 2005-05-04
PT1526848E (en) 2007-08-08
ATE367155T1 (en) 2007-08-15
WO2004014336A2 (en) 2004-02-19
CY1107739T1 (en) 2013-04-18
DE50307717D1 (en) 2007-08-30

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase