AU2003282051A1 - Pyrazole derivatives as modulators of peroxisome proliferator activated receptors - Google Patents
Pyrazole derivatives as modulators of peroxisome proliferator activated receptorsInfo
- Publication number
- AU2003282051A1 AU2003282051A1 AU2003282051A AU2003282051A AU2003282051A1 AU 2003282051 A1 AU2003282051 A1 AU 2003282051A1 AU 2003282051 A AU2003282051 A AU 2003282051A AU 2003282051 A AU2003282051 A AU 2003282051A AU 2003282051 A1 AU2003282051 A1 AU 2003282051A1
- Authority
- AU
- Australia
- Prior art keywords
- modulators
- peroxisome proliferator
- pyrazole derivatives
- activated receptors
- proliferator activated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02360298 | 2002-10-24 | ||
| EP02360298.0 | 2002-10-24 | ||
| EP02360372 | 2002-12-20 | ||
| EP02360373 | 2002-12-20 | ||
| EP02360373.1 | 2002-12-20 | ||
| EP02360372.3 | 2002-12-20 | ||
| US45695403P | 2003-03-25 | 2003-03-25 | |
| US60/456,954 | 2003-03-25 | ||
| EP03360070 | 2003-06-11 | ||
| EP03360070.1 | 2003-06-11 | ||
| EP03360091 | 2003-07-24 | ||
| EP03360091.7 | 2003-07-24 | ||
| PCT/EP2003/011855 WO2004043951A1 (en) | 2002-10-24 | 2003-10-24 | Pyrazole derivatives as modulators of peroxisome proliferator activated receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2003282051A1 true AU2003282051A1 (en) | 2004-06-03 |
Family
ID=32180796
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003287965A Abandoned AU2003287965A1 (en) | 2002-10-24 | 2003-10-22 | Modulation of peroxisome proliferator activated receptors activity |
| AU2003282051A Abandoned AU2003282051A1 (en) | 2002-10-24 | 2003-10-24 | Pyrazole derivatives as modulators of peroxisome proliferator activated receptors |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003287965A Abandoned AU2003287965A1 (en) | 2002-10-24 | 2003-10-22 | Modulation of peroxisome proliferator activated receptors activity |
Country Status (2)
| Country | Link |
|---|---|
| AU (2) | AU2003287965A1 (en) |
| WO (2) | WO2004037248A2 (en) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10315573A1 (en) * | 2003-04-05 | 2004-10-14 | Merck Patent Gmbh | Substituted pyrazoles |
| DE10315569A1 (en) | 2003-04-05 | 2004-10-14 | Merck Patent Gmbh | Substituted pyrazole compounds |
| DE10315571A1 (en) | 2003-04-05 | 2004-10-14 | Merck Patent Gmbh | pyrazole |
| AR044586A1 (en) * | 2003-06-04 | 2005-09-21 | Aventis Pharma Sa | ARIL PRODUCTS - HETEROAROMATICOS, COMPOSITIONS THAT CONTAIN THEM AND THEIR USE |
| WO2005061462A2 (en) * | 2003-12-19 | 2005-07-07 | Neurogen Corporation | Diaryl pyrazole derivatives and their use as neurokinin-3 receptor modulators |
| WO2005090313A1 (en) * | 2004-03-18 | 2005-09-29 | Pfizer Limited | N-(1-arylpyrazol-4l)sulfonamides and their use as parasiticides |
| US20060252670A1 (en) * | 2004-10-14 | 2006-11-09 | Intercept Pharmaceuticals Inc. | Method of reducing drug-induced adverse side effects in a patient |
| KR101363278B1 (en) * | 2005-06-27 | 2014-02-21 | 엑셀리시스 페이턴트 컴퍼니 엘엘씨 | Imidazole based lxr modulators |
| AU2006282403B2 (en) * | 2005-08-26 | 2011-07-07 | Institute Of Medicinal Molecular Design, Inc. | Derivative having PPAR agonistic activity |
| WO2007052843A1 (en) * | 2005-11-04 | 2007-05-10 | Takeda Pharmaceutical Company Limited | Heterocyclic amide compound and use thereof |
| WO2007122970A1 (en) * | 2006-04-20 | 2007-11-01 | Osaka University | Ligand capable of binding to nuclear receptor |
| US9315449B2 (en) | 2008-05-15 | 2016-04-19 | Duke University | Substituted pyrazoles as heat shock transcription factor activators |
| AU2010206549B2 (en) * | 2009-01-26 | 2016-08-25 | Dcb-Usa, Llc | Use of pterosin compounds for treating diabetes and obesity |
| EP2410858B1 (en) * | 2009-03-23 | 2016-09-07 | Merck Sharp & Dohme Corp. | P2x3 receptor antagonists for treatment of pain |
| AR076984A1 (en) * | 2009-06-08 | 2011-07-20 | Merck Serono Sa | DERIVATIVES OF PIRAZOL OXADIAZOL |
| PL2736887T3 (en) | 2011-07-29 | 2018-03-30 | Karyopharm Therapeutics, Inc. | Hydrazide containing nuclear transport modulators and uses thereof |
| US9428490B2 (en) * | 2011-07-29 | 2016-08-30 | Karyopharm Therapeutics Inc. | Nuclear transport modulators and uses thereof |
| TW201321367A (en) * | 2011-10-25 | 2013-06-01 | Du Pont | 1,3-diaryl-substituted heterocyclic pesticides |
| CN103254133A (en) * | 2012-02-20 | 2013-08-21 | 南京大学 | Preparation method of diarylpyrazolylaniline compounds, and application of compounds in colorectal cancer treatment |
| KR102095429B1 (en) * | 2012-05-09 | 2020-03-31 | 바이오젠 엠에이 인코포레이티드 | Nuclear transport modulators and uses thereof |
| WO2014144772A1 (en) | 2013-03-15 | 2014-09-18 | Karyopharm Therapeutics Inc. | Methods of promoting wound healing using crm1 inhibitors |
| CN110386919B (en) | 2013-06-21 | 2023-07-14 | 卡尔约药物治疗公司 | Nuclear transport modulators and uses thereof |
| EP4112615A1 (en) | 2014-08-15 | 2023-01-04 | Karyopharm Therapeutics Inc. | Compositions comprising one crystalline form of selinexor |
| US9982000B2 (en) * | 2015-04-22 | 2018-05-29 | Rigel Pharmaceuticals, Inc. | Pyrazole compounds and method for making and using the compounds |
| WO2016202935A1 (en) | 2015-06-19 | 2016-12-22 | Bayer Pharma Aktiengesellschaft | Glucose transport inhibitors |
| WO2017117535A1 (en) | 2015-12-31 | 2017-07-06 | Karyopharm Therapeutics Inc. | Nuclear transport modulators and uses thereof |
| EP3397633A1 (en) | 2015-12-31 | 2018-11-07 | Karyopharm Therapeutics, Inc. | Nuclear transport modulators and uses thereof |
| WO2017135786A1 (en) * | 2016-02-05 | 2017-08-10 | 연세대학교 산학협력단 | Novel amide compound and use thereof |
| WO2018098472A1 (en) | 2016-11-28 | 2018-05-31 | Karyopharm Therapeutics Inc. | Crm1 inhibitors for treating epilepsy |
| WO2020113094A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| WO2021041898A1 (en) | 2019-08-30 | 2021-03-04 | Rigel Pharmaceuticals, Inc. | Pyrazole compounds, formulations thereof, and a method for using the compounds and/or formulations |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO760996L (en) * | 1975-03-25 | 1976-09-28 | Byk Gulden Lomberg Chem Fab | |
| GB9604242D0 (en) * | 1996-02-28 | 1996-05-01 | Glaxo Wellcome Inc | Chemical compounds |
| AU759255B2 (en) * | 1998-01-29 | 2003-04-10 | Amgen, Inc. | PPAR-gamma modulators |
| GB9824614D0 (en) * | 1998-11-11 | 1999-01-06 | Glaxo Group Ltd | Chemical compounds |
-
2003
- 2003-10-22 WO PCT/EP2003/011710 patent/WO2004037248A2/en not_active Application Discontinuation
- 2003-10-22 AU AU2003287965A patent/AU2003287965A1/en not_active Abandoned
- 2003-10-24 AU AU2003282051A patent/AU2003282051A1/en not_active Abandoned
- 2003-10-24 WO PCT/EP2003/011855 patent/WO2004043951A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004043951A1 (en) | 2004-05-27 |
| AU2003287965A1 (en) | 2004-05-13 |
| AU2003287965A8 (en) | 2004-05-13 |
| WO2004037248A3 (en) | 2004-06-03 |
| WO2004037248A2 (en) | 2004-05-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |