AU2003269041A8 - Method and device for screening molecules in cells - Google Patents
Method and device for screening molecules in cellsInfo
- Publication number
- AU2003269041A8 AU2003269041A8 AU2003269041A AU2003269041A AU2003269041A8 AU 2003269041 A8 AU2003269041 A8 AU 2003269041A8 AU 2003269041 A AU2003269041 A AU 2003269041A AU 2003269041 A AU2003269041 A AU 2003269041A AU 2003269041 A8 AU2003269041 A8 AU 2003269041A8
- Authority
- AU
- Australia
- Prior art keywords
- cells
- screening molecules
- screening
- molecules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000034 method Methods 0.000 title 1
- 238000012216 screening Methods 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5032—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on intercellular interactions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5058—Neurological cells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00364—Pipettes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00364—Pipettes
- B01J2219/00367—Pipettes capillary
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00378—Piezoelectric or ink jet dispensers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00646—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports
- B01J2219/0065—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports by the use of liquid beads
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1034—Transferring microquantities of liquid
- G01N2035/1046—Levitated, suspended drops
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0209326A FR2842747B1 (en) | 2002-07-23 | 2002-07-23 | METHOD AND DEVICE FOR SCREENING MOLECULES IN CELLS |
FR0209326 | 2002-07-23 | ||
PCT/FR2003/002298 WO2004011938A2 (en) | 2002-07-23 | 2003-07-21 | Method and device for screening molecules in cells |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2003269041A8 true AU2003269041A8 (en) | 2004-02-16 |
AU2003269041A1 AU2003269041A1 (en) | 2004-02-16 |
Family
ID=30011408
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2003269041A Abandoned AU2003269041A1 (en) | 2002-07-23 | 2003-07-21 | Method and device for screening molecules in cells |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1525472A2 (en) |
JP (1) | JP2005533509A (en) |
AU (1) | AU2003269041A1 (en) |
CA (1) | CA2492933A1 (en) |
FR (1) | FR2842747B1 (en) |
WO (1) | WO2004011938A2 (en) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2857451B1 (en) * | 2003-07-11 | 2005-09-30 | Commissariat Energie Atomique | METHOD AND DEVICE FOR ANALYSIS OF LIVE REACTION ENVIRONMENTS |
US20090215192A1 (en) * | 2004-05-27 | 2009-08-27 | Stratos Biosystems, Llc | Solid-phase affinity-based method for preparing and manipulating an analyte-containing solution |
CA2594483C (en) | 2005-01-28 | 2014-08-26 | Duke University | Apparatuses and methods for manipulating droplets on a printed circuit board |
DE112006000657T5 (en) | 2005-03-30 | 2008-02-07 | National University Corporation Nagoya University, Nagoya | Process for producing biological organic material and culture vessel therefor |
JPWO2007063898A1 (en) * | 2005-11-29 | 2009-05-07 | 国立大学法人 東京大学 | Protein crystallization method and apparatus, and protein crystallization treatment apparatus |
US9476856B2 (en) | 2006-04-13 | 2016-10-25 | Advanced Liquid Logic, Inc. | Droplet-based affinity assays |
US20140193807A1 (en) | 2006-04-18 | 2014-07-10 | Advanced Liquid Logic, Inc. | Bead manipulation techniques |
US8809068B2 (en) | 2006-04-18 | 2014-08-19 | Advanced Liquid Logic, Inc. | Manipulation of beads in droplets and methods for manipulating droplets |
US7439014B2 (en) | 2006-04-18 | 2008-10-21 | Advanced Liquid Logic, Inc. | Droplet-based surface modification and washing |
US10078078B2 (en) | 2006-04-18 | 2018-09-18 | Advanced Liquid Logic, Inc. | Bead incubation and washing on a droplet actuator |
WO2009111769A2 (en) | 2008-03-07 | 2009-09-11 | Advanced Liquid Logic, Inc. | Reagent and sample preparation and loading on a fluidic device |
CA2712863C (en) | 2007-02-09 | 2015-01-06 | Advanced Liquid Logic, Inc. | Droplet actuator devices and methods employing magnetic beads |
WO2011084703A2 (en) | 2009-12-21 | 2011-07-14 | Advanced Liquid Logic, Inc. | Enzyme assays on a droplet actuator |
US8702938B2 (en) | 2007-09-04 | 2014-04-22 | Advanced Liquid Logic, Inc. | Droplet actuator with improved top substrate |
KR20100100974A (en) | 2007-12-23 | 2010-09-15 | 어드밴스드 리퀴드 로직, 아이엔씨. | Droplet actuator configurations and methods of conducting droplet operations |
US8852952B2 (en) | 2008-05-03 | 2014-10-07 | Advanced Liquid Logic, Inc. | Method of loading a droplet actuator |
US8926065B2 (en) | 2009-08-14 | 2015-01-06 | Advanced Liquid Logic, Inc. | Droplet actuator devices and methods |
US9091649B2 (en) | 2009-11-06 | 2015-07-28 | Advanced Liquid Logic, Inc. | Integrated droplet actuator for gel; electrophoresis and molecular analysis |
JP5887496B2 (en) | 2010-05-11 | 2016-03-16 | パナソニックIpマネジメント株式会社 | Cell culture substrate and cell culture method using the same |
CA2833897C (en) | 2011-05-09 | 2020-05-19 | Advanced Liquid Logic, Inc. | Microfluidic feedback using impedance detection |
CA2840949A1 (en) | 2011-07-06 | 2013-01-10 | Advanced Liquid Logic Inc | Reagent storage on a droplet actuator |
US9513253B2 (en) | 2011-07-11 | 2016-12-06 | Advanced Liquid Logic, Inc. | Droplet actuators and techniques for droplet-based enzymatic assays |
WO2013016413A2 (en) | 2011-07-25 | 2013-01-31 | Advanced Liquid Logic Inc | Droplet actuator apparatus and system |
US10731199B2 (en) | 2011-11-21 | 2020-08-04 | Advanced Liquid Logic, Inc. | Glucose-6-phosphate dehydrogenase assays |
KR102070330B1 (en) | 2012-06-27 | 2020-01-28 | 어드밴스드 리퀴드 로직, 아이엔씨. | Techniques and droplet actuator designs for reducing bubble formation |
WO2014165273A1 (en) | 2013-03-13 | 2014-10-09 | Innovative Surface Technologies, Inc. | Conical devices for three-dimensional aggregate (s) of eukaryotic cells |
GB201614150D0 (en) | 2016-08-18 | 2016-10-05 | Univ Oxford Innovation Ltd | Microfluidic arrangements |
WO2017064514A1 (en) | 2015-10-16 | 2017-04-20 | Oxford University Innovation Limited | Microfluidic arrangements |
GB201518392D0 (en) * | 2015-10-16 | 2015-12-02 | Isis Innovation | Microfluidic arrangements |
CN114867556B (en) * | 2019-11-06 | 2023-09-15 | 高丽大学校算学协力团 | Droplet-based deformation method for delivering material into cells and chip therefor |
JP7135049B2 (en) * | 2020-10-12 | 2022-09-12 | エコール ポリテクニック | Methods for handling microdroplets containing samples |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPN923596A0 (en) * | 1996-04-12 | 1996-05-09 | Australian Biomedical Corporation Limited | Method and apparatus for treatment of human or animal cell samples |
AU6571598A (en) * | 1997-03-18 | 1998-10-12 | Chromaxome Corporation | Methods for screening compounds using encapsulated cells |
GB9808836D0 (en) * | 1998-04-27 | 1998-06-24 | Amersham Pharm Biotech Uk Ltd | Microfabricated apparatus for cell based assays |
FR2857451B1 (en) * | 2003-07-11 | 2005-09-30 | Commissariat Energie Atomique | METHOD AND DEVICE FOR ANALYSIS OF LIVE REACTION ENVIRONMENTS |
-
2002
- 2002-07-23 FR FR0209326A patent/FR2842747B1/en not_active Expired - Fee Related
-
2003
- 2003-07-21 CA CA002492933A patent/CA2492933A1/en not_active Abandoned
- 2003-07-21 JP JP2004523860A patent/JP2005533509A/en active Pending
- 2003-07-21 WO PCT/FR2003/002298 patent/WO2004011938A2/en not_active Application Discontinuation
- 2003-07-21 EP EP03750828A patent/EP1525472A2/en not_active Withdrawn
- 2003-07-21 AU AU2003269041A patent/AU2003269041A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2004011938A3 (en) | 2004-08-05 |
CA2492933A1 (en) | 2004-02-05 |
EP1525472A2 (en) | 2005-04-27 |
WO2004011938B1 (en) | 2004-09-16 |
FR2842747A1 (en) | 2004-01-30 |
WO2004011938A2 (en) | 2004-02-05 |
FR2842747B1 (en) | 2004-10-15 |
JP2005533509A (en) | 2005-11-10 |
AU2003269041A1 (en) | 2004-02-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |