AU2003268478A1 - Cardiolipin molecules and method of synthesis - Google Patents
Cardiolipin molecules and method of synthesisInfo
- Publication number
- AU2003268478A1 AU2003268478A1 AU2003268478A AU2003268478A AU2003268478A1 AU 2003268478 A1 AU2003268478 A1 AU 2003268478A1 AU 2003268478 A AU2003268478 A AU 2003268478A AU 2003268478 A AU2003268478 A AU 2003268478A AU 2003268478 A1 AU2003268478 A1 AU 2003268478A1
- Authority
- AU
- Australia
- Prior art keywords
- synthesis
- cardiolipin molecules
- cardiolipin
- molecules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
Applications Claiming Priority (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41927702P | 2002-10-16 | 2002-10-16 | |
US60/419,277 | 2002-10-16 | ||
US42928502P | 2002-11-26 | 2002-11-26 | |
US60/429,285 | 2002-11-26 | ||
US43865903P | 2003-01-07 | 2003-01-07 | |
US60/438,659 | 2003-01-07 | ||
US46733103P | 2003-05-02 | 2003-05-02 | |
US60/467,331 | 2003-05-02 | ||
PCT/US2003/013917 WO2004062569A2 (en) | 2003-01-07 | 2003-05-04 | Cardiolipin compositions their methods of preparation and use |
AU2003300770 | 2003-05-04 | ||
PCT/US2003/016412 WO2003099830A2 (en) | 2002-05-24 | 2003-05-23 | Cardiolipin compositions, methods of preparation and use |
AU2003239614 | 2003-05-23 | ||
PCT/US2003/027806 WO2004039817A1 (en) | 2002-10-16 | 2003-09-05 | Cardiolipin molecules and method of synthesis |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2003268478A1 true AU2003268478A1 (en) | 2004-05-25 |
Family
ID=32234368
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2003268478A Abandoned AU2003268478A1 (en) | 2002-10-16 | 2003-09-05 | Cardiolipin molecules and method of synthesis |
AU2003277445A Abandoned AU2003277445A1 (en) | 2002-10-16 | 2003-10-16 | Cationic cardiolipin analogs and use thereof |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2003277445A Abandoned AU2003277445A1 (en) | 2002-10-16 | 2003-10-16 | Cationic cardiolipin analogs and use thereof |
Country Status (7)
Country | Link |
---|---|
EP (2) | EP1556392A1 (en) |
JP (2) | JP2006510733A (en) |
AU (2) | AU2003268478A1 (en) |
CA (2) | CA2502285A1 (en) |
EA (2) | EA200500659A1 (en) |
HK (1) | HK1080087A1 (en) |
WO (2) | WO2004039817A1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8815599B2 (en) | 2004-06-01 | 2014-08-26 | Pronai Therapeutics, Inc. | Methods and compositions for the inhibition of gene expression |
WO2006004935A2 (en) * | 2004-06-29 | 2006-01-12 | Neopharm, Inc. | Pegylated cardiolipin analogs, methods of synthesis, and uses thereof |
MX2007005591A (en) * | 2004-11-08 | 2008-02-12 | Neopharm Inc | Synthesis of cardiolipin analogues and uses thereof. |
US8895717B2 (en) | 2005-04-15 | 2014-11-25 | The Board Of Regents Of The University Of Texas System | Delivery of siRNA by neutral lipid compositions |
WO2007014150A2 (en) * | 2005-07-22 | 2007-02-01 | Neopharm, Inc. | Method of administering liposomes containing oligonucleotides |
WO2007065017A2 (en) * | 2005-12-01 | 2007-06-07 | Pronai Therapeutics, Inc. | Oligonucleotide cationic liposomal delivery system |
WO2007064857A2 (en) | 2005-12-01 | 2007-06-07 | Pronai Therapeutics, Inc. | Amphoteric liposome formulation |
JP2009527576A (en) * | 2006-02-24 | 2009-07-30 | ネオフアーム・インコーポレイテツド | Methods and steps for cardiolipin preparation |
PL2344198T3 (en) * | 2008-09-27 | 2021-05-31 | Jina Pharmaceuticals Inc. | Lipid based pharmaceutical preparations for topical application |
CA2870036A1 (en) * | 2012-04-11 | 2013-10-17 | Lipoxen Technologies Limited | Liposomes containing oligopeptide fragments of myelin basic protein, a pharmaceutical composition and a method for treatment of multiple sclerosis |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2113606A (en) * | 1934-05-24 | 1938-04-12 | Alba Pharmaceutical Company In | Quaternary ammonium compounds |
US6461637B1 (en) * | 2000-09-01 | 2002-10-08 | Neopharm, Inc. | Method of administering liposomal encapsulated taxane |
JP4854853B2 (en) * | 1998-11-12 | 2012-01-18 | ライフ テクノロジーズ コーポレーション | Transfection drug |
ATE283254T1 (en) * | 1999-05-28 | 2004-12-15 | Vical Inc | CYTOFECTIN DIMERS AND METHOD FOR USE THEREOF |
-
2003
- 2003-09-05 EP EP03749443A patent/EP1556392A1/en not_active Withdrawn
- 2003-09-05 AU AU2003268478A patent/AU2003268478A1/en not_active Abandoned
- 2003-09-05 JP JP2005501873A patent/JP2006510733A/en active Pending
- 2003-09-05 EA EA200500659A patent/EA200500659A1/en unknown
- 2003-09-05 WO PCT/US2003/027806 patent/WO2004039817A1/en not_active Application Discontinuation
- 2003-09-05 CA CA002502285A patent/CA2502285A1/en not_active Abandoned
- 2003-10-16 JP JP2005501473A patent/JP2006503112A/en active Pending
- 2003-10-16 WO PCT/US2003/033099 patent/WO2004035523A1/en not_active Application Discontinuation
- 2003-10-16 CA CA002501990A patent/CA2501990A1/en not_active Abandoned
- 2003-10-16 EA EA200500661A patent/EA200500661A1/en unknown
- 2003-10-16 EP EP03809159A patent/EP1558562A1/en not_active Withdrawn
- 2003-10-16 AU AU2003277445A patent/AU2003277445A1/en not_active Abandoned
-
2005
- 2005-12-30 HK HK05112200.6A patent/HK1080087A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
HK1080087A1 (en) | 2006-04-21 |
EA200500659A1 (en) | 2005-10-27 |
EP1558562A1 (en) | 2005-08-03 |
AU2003277445A1 (en) | 2004-05-04 |
CA2502285A1 (en) | 2004-05-13 |
EP1556392A1 (en) | 2005-07-27 |
WO2004035523A1 (en) | 2004-04-29 |
WO2004039817A9 (en) | 2004-07-22 |
JP2006503112A (en) | 2006-01-26 |
EA200500661A1 (en) | 2005-10-27 |
CA2501990A1 (en) | 2004-04-29 |
JP2006510733A (en) | 2006-03-30 |
WO2004035523B1 (en) | 2004-08-26 |
WO2004039817A1 (en) | 2004-05-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |