AU2003262794A8 - Total synthesis of heparin - Google Patents
Total synthesis of heparinInfo
- Publication number
- AU2003262794A8 AU2003262794A8 AU2003262794A AU2003262794A AU2003262794A8 AU 2003262794 A8 AU2003262794 A8 AU 2003262794A8 AU 2003262794 A AU2003262794 A AU 2003262794A AU 2003262794 A AU2003262794 A AU 2003262794A AU 2003262794 A8 AU2003262794 A8 AU 2003262794A8
- Authority
- AU
- Australia
- Prior art keywords
- heparin
- total synthesis
- synthesis
- total
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40563402P | 2002-08-23 | 2002-08-23 | |
| US60/405,634 | 2002-08-23 | ||
| PCT/US2003/026349 WO2004017910A2 (en) | 2002-08-23 | 2003-08-22 | Total synthesis of heparin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2003262794A1 AU2003262794A1 (en) | 2004-03-11 |
| AU2003262794A8 true AU2003262794A8 (en) | 2004-03-11 |
Family
ID=31946908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003262794A Abandoned AU2003262794A1 (en) | 2002-08-23 | 2003-08-22 | Total synthesis of heparin |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU2003262794A1 (en) |
| WO (1) | WO2004017910A2 (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040171819A1 (en) | 2002-10-10 | 2004-09-02 | Aventis Pharma S.A. | Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them |
| US20090197308A1 (en) * | 2005-05-12 | 2009-08-06 | Jian Liu | Enzymatic synthesis of sulfated polysaccharides |
| AU2006316039B2 (en) * | 2005-11-21 | 2011-08-18 | Ge Healthcare Bio-Sciences Ab | A method of chromatography using semi-synthetic heparin ligands |
| US7745584B2 (en) * | 2006-05-22 | 2010-06-29 | California Institute Of Technology | Antibodies to sulfated carbohydrates |
| US8912149B1 (en) | 2007-11-28 | 2014-12-16 | California Institute Of Technology | Glycosaminoglycan mimetics |
| US11203772B2 (en) | 2010-12-23 | 2021-12-21 | The University Of North Carolina At Chapel Hill | Chemoenzymatic synthesis of structurally homogeneous ultra-low molecular weight heparins |
| CN105452479B (en) * | 2013-06-17 | 2021-05-18 | 北卡罗来纳大学查珀尔希尔分校 | Reversible heparin molecules |
| US10227370B2 (en) | 2013-08-02 | 2019-03-12 | California Institute Of Technology | Heparan sulfate/heparin mimetics with anti-chemokine and anti-inflammatory activity |
| US9770461B2 (en) | 2013-08-02 | 2017-09-26 | California Institute Of Technology | Tailored glycopolymers as anticoagulant heparin mimetics |
| CN110191958A (en) * | 2017-01-19 | 2019-08-30 | 味之素株式会社 | Produce the method with the heparosan compound of the hexuronic acid residue through isomerization |
| JP7330893B2 (en) | 2017-03-10 | 2023-08-22 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | Short-acting heparin-based antiaggregant compounds and methods |
| US11865137B2 (en) | 2017-11-03 | 2024-01-09 | The University Of North Carolina At Chapel Hill | Sulfated oligosaccharides having anti-inflammatory activity |
| JP2021528421A (en) | 2018-06-20 | 2021-10-21 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒルＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｎｏｒｔｈ Ｃａｒｏｌｉｎａ Ａｔ Ｃｈａｐｅｌ Ｈｉｌｌ | Cell protection methods and compositions |
| HRP20231510T1 (en) * | 2018-07-11 | 2024-03-01 | Ajinomoto Co., Inc. | Method for enzymatic sulfurylation of alcohols and amines using bacterium of the family enterobacteriaceae |
| WO2021007429A1 (en) * | 2019-07-09 | 2021-01-14 | Optimvia Llc | Methods for synthesizing anticoagulant polysaccharides |
| CN114763518B (en) * | 2021-09-10 | 2023-04-28 | 江南大学 | Construction and application of yeast engineering bacteria for producing heparin by fermentation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6030807A (en) * | 1996-09-10 | 2000-02-29 | The Rockefeller University | Highly regulable promoter for heterologous gene expression |
-
2003
- 2003-08-22 AU AU2003262794A patent/AU2003262794A1/en not_active Abandoned
- 2003-08-22 WO PCT/US2003/026349 patent/WO2004017910A2/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003262794A1 (en) | 2004-03-11 |
| WO2004017910A2 (en) | 2004-03-04 |
| WO2004017910A3 (en) | 2004-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |