AU2003208289A1 - Deuterated spirocyclopentanimidazolinones and the use thereof in the treatment of cardiovascular diseases - Google Patents

Deuterated spirocyclopentanimidazolinones and the use thereof in the treatment of cardiovascular diseases

Info

Publication number
AU2003208289A1
AU2003208289A1 AU2003208289A AU2003208289A AU2003208289A1 AU 2003208289 A1 AU2003208289 A1 AU 2003208289A1 AU 2003208289 A AU2003208289 A AU 2003208289A AU 2003208289 A AU2003208289 A AU 2003208289A AU 2003208289 A1 AU2003208289 A1 AU 2003208289A1
Authority
AU
Australia
Prior art keywords
spirocyclopentanimidazolinones
deuterated
treatment
cardiovascular diseases
cardiovascular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003208289A
Inventor
Rudolf-Giesbert Alken
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TURICUM DRUG DEVELOPMENT AG
Original Assignee
BDD GROUP HOLDING AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BDD GROUP HOLDING AG filed Critical BDD GROUP HOLDING AG
Publication of AU2003208289A1 publication Critical patent/AU2003208289A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003208289A 2002-02-07 2003-02-06 Deuterated spirocyclopentanimidazolinones and the use thereof in the treatment of cardiovascular diseases Abandoned AU2003208289A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10205432.0 2002-02-07
DE10205432A DE10205432A1 (en) 2002-02-07 2002-02-07 Deuterated biphenyl-substituted spirocyclopentanimidazolines and medicinal products containing these compounds
PCT/DE2003/000366 WO2003066627A1 (en) 2002-02-07 2003-02-06 Deuterated spirocyclopentanimidazolinones and the use thereof in the treatment of cardiovascular diseases

Publications (1)

Publication Number Publication Date
AU2003208289A1 true AU2003208289A1 (en) 2003-09-02

Family

ID=27618513

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003208289A Abandoned AU2003208289A1 (en) 2002-02-07 2003-02-06 Deuterated spirocyclopentanimidazolinones and the use thereof in the treatment of cardiovascular diseases

Country Status (3)

Country Link
AU (1) AU2003208289A1 (en)
DE (1) DE10205432A1 (en)
WO (1) WO2003066627A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008067378A2 (en) * 2006-11-28 2008-06-05 Auspex Pharmaceuticals, Inc. Preparation and utility of substituted phenyltetrazoles

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223269A (en) * 1989-08-31 1993-06-29 Andrejs Liepins Methods and composition for the treatment of hypertension
US5270317A (en) * 1990-03-20 1993-12-14 Elf Sanofi N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present
BR9507200A (en) * 1994-03-25 1997-09-16 Isotechnika Inc Improved drug efficacy by deuteration

Also Published As

Publication number Publication date
DE10205432A1 (en) 2003-08-21
WO2003066627A1 (en) 2003-08-14

Similar Documents

Publication Publication Date Title
AU2003264282A1 (en) Phenethanolamine derivatives and their use in the treatment of respiratory diseases
HK1068885A1 (en) N-pyrazinyl-phenylsulphonamides and their use in the treatment of chemokine mediated diseases n--
AU2003243551A1 (en) Use of an anti-endotoxin drug in the prevention and treatment of disease
AU2003212323A1 (en) Benzodiazepine-substituted piperidines for utilization in the treatment of cardiovascular diseases
HK1162948A1 (en) Hemiasterlin derivatives and uses thereof in the treatment of cancer (hemiasterlin)
EP1476150A4 (en) Carboxyfullerenes and methods of use thereof
AU2003286285A1 (en) Use of fgf-18 in the diagnosis and treatment of memory disorders
AU2003265620A1 (en) Cardiovascular therapy composition including transfer factor and therapeutic methods including use of the composition
GB0615918D0 (en) Composition and its therapeutic use
AU2003238242A1 (en) Use of an anti-endotoxin drug in the prevention and treatment of disease
AU2003274963A1 (en) Mda-7 and free radicals in the treatment of cancer
AU2003206945A1 (en) Use of proteinase inhibitors in the treatment of autoimmune diseases
IL162941A0 (en) Carboxamidine derivatives and their use in the treatment of vascular diseases
AU2003287802A1 (en) Palpometer and methods of use thereof
AU2002352566A1 (en) Use of corrinoids in the treatment of skin diseases
AU2003244455A1 (en) Piperidylcarboxamide derivatives and their use in the treatment of tachykinim-mediated diseases
AU2003245858A1 (en) Uses of ngal-binding substances in the diagnosis and treatment of cancer diseases
AU2003270350A1 (en) Isoxazoles and their use in the treatment of ischemic diseases
AU2003244437A1 (en) Quinoxalinones and their use especially in the treatment of cardiovascular diseases
AU2003208289A1 (en) Deuterated spirocyclopentanimidazolinones and the use thereof in the treatment of cardiovascular diseases
AU2002953223A0 (en) Novel therapeutic molecules and uses thereof
AU2003219664A1 (en) Methods and therapeutic compositions in the treatment of advanced cancer
AU2003240446A1 (en) Use of mob-5 in pain
WO2005042707A9 (en) Taspasel 1 and methods of use
AU2003280867A1 (en) Specific haplotypes of the mdr1 gene and their use in diagnosis and therapy

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase