AU2002323180A1 - Hydroxypyridonate and hydroxypyrimidinone chelating agents - Google Patents

Hydroxypyridonate and hydroxypyrimidinone chelating agents

Info

Publication number: AU2002323180A1
Authority: AU; Australia
Prior art keywords: hydroxypyridonate; hydroxypyrimidinone; chelating agents; chelating; agents
Prior art date: 2001-08-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2002323180A

Inventor

Daniel M. J. Doble

Kenneth N. Raymond

Christopher J. Sunderland

Marlon Thompson

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

University of California

Original Assignee

University of California

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-08-13

Filing date

2002-08-13

Publication date

2003-03-03

2002-08-13 Application filed by University of California filed Critical University of California

2003-03-03 Publication of AU2002323180A1 publication Critical patent/AU2002323180A1/en

Status Abandoned legal-status Critical Current

Links

ISAKRJDGNUQOIC-UHFFFAOYSA-N Uracil Chemical compound O=C1C=CNC(=O)N1 ISAKRJDGNUQOIC-UHFFFAOYSA-N 0.000 title 1
239000002738 chelating agent Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/12—Macromolecular compounds
- A61K49/126—Linear polymers, e.g. dextran, inulin, PEG

AU2002323180A 2001-08-13 2002-08-13 Hydroxypyridonate and hydroxypyrimidinone chelating agents Abandoned AU2002323180A1 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US31213201P	2001-08-13	2001-08-13
US60/312,132		2001-08-13
US10/194,502		2002-07-12
US10/194,502 US6846915B2 (en)	2001-08-13	2002-07-12	Hydroxypyridonate and hydroxypyrimidinone chelating agents
PCT/US2002/026026 WO2003016923A2 (en)	2001-08-13	2002-08-13	Hydroxypyridonate and hydroxypyrimidinone chelating agents

Publications (1)

Publication Number	Publication Date
AU2002323180A1 true AU2002323180A1 (en)	2003-03-03

Family

ID=26890090

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2002323180A Abandoned AU2002323180A1 (en)	2001-08-13	2002-08-13	Hydroxypyridonate and hydroxypyrimidinone chelating agents

Country Status (6)

Country	Link
US (2)	US6846915B2 (en)
EP (1)	EP1423399A4 (en)
JP (1)	JP2005500387A (en)
AU (1)	AU2002323180A1 (en)
CA (1)	CA2456161A1 (en)
WO (1)	WO2003016923A2 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
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US6846915B2 (en) *	2001-08-13	2005-01-25	The Regents Of The University Of California	Hydroxypyridonate and hydroxypyrimidinone chelating agents
DE102004062258B3 (en) *	2004-12-23	2006-01-05	Schering Ag	New hydroxypyrimidone, hydroxypyridinone or dihydroxybenzene derivatives useful for preparing conjugates of biomolecules useful as magnetic resonance contrast agents
US7728869B2 (en) *	2005-06-14	2010-06-01	Lg Electronics Inc.	Matching camera-photographed image with map data in portable terminal and travel route guidance method
WO2007002109A2 (en) *	2005-06-20	2007-01-04	The Regents Of The University Of California	Multidentate pyrone-derived chelators for medicinal imaging and chelation
US20060292698A1 (en) *	2005-06-24	2006-12-28	Hartle Jennifer W	Spectroscopic methods for detecting and identifying chelates
EP2015784A4 (en) *	2006-05-03	2012-12-26	Wisconsin Alumni Res Found	Magnetic resonance imaging contrast agents synthesized using ring-opening metathesis polymerization
EP2511266B1 (en) *	2006-07-10	2019-09-04	The Regents of The University of California	Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides
EP2104662A2 (en) *	2007-01-11	2009-09-30	GE Healthcare AS	Chelating agents
US8475768B2 (en) *	2007-08-13	2013-07-02	Ge Healthcare As	Paramagnetic chelates thereof and their use as contrast agents in magnetic resonance imaging (MRI)
US20100008864A1 (en) *	2008-07-10	2010-01-14	Andreas Meijer	Aromatic multimers
EP2470513B1 (en)	2009-08-24	2014-10-08	Lumiphore, Inc.	Macrocyclic hopo chelators
AU2010336403B2 (en)	2009-12-24	2016-04-21	Lumiphore, Inc.	Radiopharmaceutical complexes
WO2011109521A1 (en)	2010-03-02	2011-09-09	University Of Kansas	Polyamine-dihydroxybenzoic acid conjugate hydrogels as iron chelators
WO2013187971A2 (en)	2012-05-31	2013-12-19	The Regents Of The University Of California	Macrocycles
AU2013344514B2 (en)	2012-11-16	2017-09-14	Lumiphore, Inc.	Di-Macrocycles
US11453652B2 (en)	2013-03-15	2022-09-27	Lumiphore, Inc.	Di-macrocycles
ES2898633T3 (en)	2014-04-09	2022-03-08	Lumiphore Inc	macrocycles
EP3237429A4 (en)	2014-12-22	2018-08-15	Lumiphore, Inc.	Functionalized linear ligands and complexes thereof
US10982136B2 (en)	2016-02-26	2021-04-20	The Regents Of The University Of California	Ligand-sensitized lanthanide nanocrystals as ultraviolet downconverters
CA3022852A1 (en) *	2016-05-03	2017-11-09	The Regents Of The University Of California	Formulations and treatments employing hydroxypyridonate actinide/lanthanide decorporation agents
WO2018044812A2 (en)	2016-08-29	2018-03-08	Fred Hutchinson Cancer Research Center	Chelating platform for delivery of radionuclides
WO2018045385A1 (en)	2016-09-02	2018-03-08	Lumiphore, Inc.	Macrocyclic ligands with pendant chelating moieties and complexes thereof
US11684614B2 (en)	2016-09-06	2023-06-27	The Regents Of The University Of California	Formulations of hydroxypyridonate actinide/lanthanide decorporation agents
JP7323737B2 (en)	2016-09-29	2023-08-09	ザリージェンツオブザユニバーシティオブカリフォルニア	Separation of metal ions by liquid-liquid extraction
US11136251B2 (en) *	2017-03-23	2021-10-05	Regents Of The University Of Minnesota	Compositions, methods, and devices for capturing phosphate from water
CA3093247A1 (en)	2018-03-07	2019-09-12	Lumiphore, Inc.	Macrocyclic ligands with pendant chelating moieties and complexes thereof
CN110563704A (en) *	2019-09-23	2019-12-13	南京工业大学	Tetrahedral cage assembled based on four-hydrogen bond and coordination bond synergistic effect and preparation method thereof
TW202140432A (en) *	2020-01-10	2021-11-01	加拿大商融合製藥公司	Macrocyclic chelates and uses thereof

Family Cites Families (16)

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Publication number	Priority date	Publication date	Assignee	Title
US4543213A (en)	1978-07-24	1985-09-24	The United States Of America As Represented By The United States Department Of Energy	Process for preparing 2,3-dihydroxybenzoic acid amides of tetraazaalkanes and cycloalkanes
US4309305A (en)	1978-07-24	1982-01-05	The United States As Represented By The United States Department Of Energy	In vitro removal of actinide (IV) ions
US4181654A (en)	1978-07-24	1980-01-01	The United States Of America As Represented By The United States Department Of Energy	2,3-Dihydroxybenzoic acid amides of tetraazaalkanes and tetaaza cycloalkanes
US4442305A (en)	1981-08-24	1984-04-10	The United States Of America As Represented By The United States Department Of Energy	Polycatecholamide chelating agents
GB8325494D0 (en)	1983-09-23	1983-10-26	Hider R C	Pharmaceutical compositions
US5010191A (en)	1985-08-19	1991-04-23	The Regents Of The University Of California	Imaging agents for in vivo magnetic resonance and scintigraphic imaging
US4698431A (en)	1985-11-12	1987-10-06	The United States Of America As Represented By The United States Department Of Energy	Hydroxypyridonate chelating agents
US4939254A (en)	1988-04-26	1990-07-03	The Regents Of The University Of California	Template synthesis of macrocyclic catecholamide complexes
US5049280A (en)	1989-03-29	1991-09-17	The Regents Of The University Of California	2,3-dihydroxyterephthalamides as highly effective metal ion sequestering compounds
US5624901A (en) *	1994-04-15	1997-04-29	The Regents Of The University Of California	3-hydroxy-2(1H)-pyridinone chelating agents
ATE266006T1 (en) *	1995-06-14	2004-05-15	Univ California	3-HYDROXY-2(1H)-PYRIDONE AS A CHELATING AGENT
DE59611243D1 (en)	1995-09-29	2005-08-11	Novartis Ag	hydroxypyridinones
CA2371818C (en) *	1999-02-18	2009-01-06	The Regents Of The University Of California	Salicylamide-lanthanide complexes for use as luminescent markers
WO2000048990A1 (en) *	1999-02-18	2000-08-24	The Regents Of The University Of California	Phthalamide-lanthanide complexes for use as luminescent markers
US6221476B1 (en)	1999-06-11	2001-04-24	Ibc Advanced Technologies, Inc.	Polymeric membranes functionalized with polyhydroxypyridinone ligands
US6846915B2 (en) *	2001-08-13	2005-01-25	The Regents Of The University Of California	Hydroxypyridonate and hydroxypyrimidinone chelating agents

2002
- 2002-07-12 US US10/194,502 patent/US6846915B2/en not_active Expired - Lifetime
- 2002-08-13 CA CA002456161A patent/CA2456161A1/en not_active Abandoned
- 2002-08-13 EP EP02757145A patent/EP1423399A4/en not_active Withdrawn
- 2002-08-13 AU AU2002323180A patent/AU2002323180A1/en not_active Abandoned
- 2002-08-13 JP JP2003521377A patent/JP2005500387A/en active Pending
- 2002-08-13 WO PCT/US2002/026026 patent/WO2003016923A2/en active Application Filing
2004
- 2004-07-30 US US10/902,772 patent/US7718781B2/en active Active

Also Published As

Publication number	Publication date
US7718781B2 (en)	2010-05-18
EP1423399A2 (en)	2004-06-02
US20050008570A1 (en)	2005-01-13
WO2003016923A2 (en)	2003-02-27
WO2003016923A3 (en)	2003-12-11
US20030095922A1 (en)	2003-05-22
JP2005500387A (en)	2005-01-06
US6846915B2 (en)	2005-01-25
CA2456161A1 (en)	2003-02-27
EP1423399A4 (en)	2008-05-07

Legal Events

Date	Code	Title	Description
2004-05-06	MK6	Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase

Publication	Publication Date	Title
AU2002323180A1 (en)	2003-03-03	Hydroxypyridonate and hydroxypyrimidinone chelating agents
AU2002357119A1 (en)	2003-06-30	Mitocidal compositions and methods
AU2001288040A1 (en)	2002-03-26	Homeostasis-maintaining agents
AU2002214284A1 (en)	2002-05-27	Anti-helicobacterial agents
EP1151667A3 (en)	2003-01-29	Plant-activating agent
IL154553A0 (en)	2003-09-17	Urocortin-iii and uses thereof
AU2002224553A1 (en)	2002-02-05	Human proteases
AU2001292936A1 (en)	2002-04-02	Octahydro-indolizines and quinolizines and hexahydro-pyrrolizines
AU2002357748A1 (en)	2003-06-10	Osteopontin-related compositions and methods
AU2002359694A1 (en)	2003-06-30	Compounds and methods
AU2001295185A1 (en)	2001-11-07	Multiplexing-interleaving and demultiplexing-deinterleaving
GB0126889D0 (en)	2002-01-02	Compounds and their uses
IL160539A0 (en)	2004-07-25	Anti-influenzal agents
AU2001232332A1 (en)	2001-09-17	Leptin-resistance ameliorating agents
AU2002301358A1 (en)	2003-06-12	Improvements in Transmissometers
AU2002301354A1 (en)	2003-06-12	Improvements in Transmissometers
AU2002348913A1 (en)	2003-06-10	Cool-zone iron
AU2001274683A1 (en)	2001-12-03	Contrast agents
AU2002359869A1 (en)	2003-07-24	Pak5-related compositions and methods
GB0106987D0 (en)	2001-05-09	Immunotherapeuitic agent
GB0122162D0 (en)	2001-10-31	Agent
AU2002361263A1 (en)	2003-07-09	Pants-covering and shoe-covering garments
AU2001277537A1 (en)	2002-03-04	Agents
AU2001246829A1 (en)	2001-10-15	Vital tissue-protecting agents
AU2002344495A1 (en)	2003-05-26	Anticaner agents