AU2002254114A1 - Non-imidazole aryl alkylamines compounds as histamine h3 receptor antagonists, preparation and therapeutic uses - Google Patents

Non-imidazole aryl alkylamines compounds as histamine h3 receptor antagonists, preparation and therapeutic uses

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Publication number
AU2002254114A1
AU2002254114A1 AU2002254114A AU2002254114A AU2002254114A1 AU 2002254114 A1 AU2002254114 A1 AU 2002254114A1 AU 2002254114 A AU2002254114 A AU 2002254114A AU 2002254114 A AU2002254114 A AU 2002254114A AU 2002254114 A1 AU2002254114 A1 AU 2002254114A1
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Australia
Prior art keywords
histamine
imidazole
compounds
preparation
receptor antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002254114A
Inventor
Lisa Selsam Beavers
Robert Alan Gadski
Philip Arthur Hipskind
Craig William Lindsley
Karen Lynn Lobb
James Arthur Nixon
Richard Todd Pickard
John Mehnert Schaus
Takako Takakuwa
Brian Morgan Watson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
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Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of AU2002254114A1 publication Critical patent/AU2002254114A1/en
Abandoned legal-status Critical Current

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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
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    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
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