AU2002236861A1 - Method of treatment of neurodegenerative disorders using pentaaza-macrocyclic ligand complexes - Google Patents

Method of treatment of neurodegenerative disorders using pentaaza-macrocyclic ligand complexes

Info

Publication number
AU2002236861A1
AU2002236861A1 AU2002236861A AU2002236861A AU2002236861A1 AU 2002236861 A1 AU2002236861 A1 AU 2002236861A1 AU 2002236861 A AU2002236861 A AU 2002236861A AU 2002236861 A AU2002236861 A AU 2002236861A AU 2002236861 A1 AU2002236861 A1 AU 2002236861A1
Authority
AU
Australia
Prior art keywords
pentaaza
treatment
neurodegenerative disorders
ligand complexes
macrocyclic ligand
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002236861A
Inventor
Dennis P. Riley
Daniela Salvemini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Metaphore Pharmaceuticals Inc
Original Assignee
Metaphore Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metaphore Pharmaceuticals Inc filed Critical Metaphore Pharmaceuticals Inc
Publication of AU2002236861A1 publication Critical patent/AU2002236861A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
AU2002236861A 2001-01-26 2002-01-23 Method of treatment of neurodegenerative disorders using pentaaza-macrocyclic ligand complexes Abandoned AU2002236861A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26449301P 2001-01-26 2001-01-26
US60/264,493 2001-01-26
PCT/US2002/002108 WO2002058686A2 (en) 2001-01-26 2002-01-23 Method of treatment of neurodegenerative disorders using pentaaza-macrocyclic ligand complexes

Publications (1)

Publication Number Publication Date
AU2002236861A1 true AU2002236861A1 (en) 2002-08-06

Family

ID=23006301

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002236861A Abandoned AU2002236861A1 (en) 2001-01-26 2002-01-23 Method of treatment of neurodegenerative disorders using pentaaza-macrocyclic ligand complexes

Country Status (3)

Country Link
EP (1) EP1353655A2 (en)
AU (1) AU2002236861A1 (en)
WO (1) WO2002058686A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITTO20040124A1 (en) 2004-03-01 2004-06-01 Medestea Internaz Srl NEW USES IN THERAPY OF N-PIPERIDINE DERIVATIVES PARTICULARLY FOR THE TREATMENT OF NEURODEGENERATIVE PATHOLOGIES
LT2056675T (en) 2006-10-12 2019-05-27 Galera Labs, Llc Methods of treating oral mucositis
CN103906756B (en) 2011-09-26 2020-03-03 加莱拉实验室有限责任公司 Methods for treating diseases
PL3334744T3 (en) 2015-08-11 2020-09-21 Galera Labs, Llc Pentaaza macrocyclic ring complexes possessing oral bioavailability
US10987367B2 (en) 2016-11-28 2021-04-27 Texas Tech University System Drug targets of delayed aging and human brain diseases
JP2020507598A (en) 2017-02-15 2020-03-12 ガレラ・ラブス・リミテッド・ライアビリティ・カンパニーＧａｌｅｒａ Ｌａｂｓ， Ｌｌｃ Pentaazamacrocyclic complexes for local intestinal delivery
EA201992431A1 (en) 2017-10-13 2020-03-13 ГАЛЕРА ЛЭБЗ, ЭлЭлСи COMBINED CANCER IMMUNOTHERAPY USING PENTA-ASA-MACROCYCLIC RING COMPLEX
CN114502179A (en) * 2019-10-10 2022-05-13 加莱拉实验室有限责任公司 Method for preparing aqueous formulations containing manganese complexes, formulations and methods of treatment

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5426122A (en) * 1989-03-17 1995-06-20 Cedars-Sinai Medical Center Methods for reducing blood pressure with dimercaptosuccinic acid (DMSA)
WO1993002090A1 (en) * 1991-07-19 1993-02-04 Monsanto Company Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
US5696109A (en) * 1992-12-07 1997-12-09 Eukarion, Inc. Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease
US5747026A (en) * 1993-10-15 1998-05-05 University Of Alabama At Birmingham Research Foundation Antioxidants
BR9707978A (en) * 1996-03-13 1999-07-27 Monsanto Co Iron complexes of nitrogen-containing macrocyclic binders effective as catalysts for superoxide dismutation
US6214817B1 (en) * 1997-06-20 2001-04-10 Monsanto Company Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity
US6180620B1 (en) * 1997-06-20 2001-01-30 G.D. Searle & Co. Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals
GB9801398D0 (en) * 1998-01-22 1998-03-18 Anggard Erik E Chemical compounds
GB9824282D0 (en) * 1998-11-05 1998-12-30 Microbiological Research Agenc Delivery of superoxide dismutase to neuronal cells

Also Published As

Publication number Publication date
WO2002058686A2 (en) 2002-08-01
WO2002058686A3 (en) 2003-02-06
EP1353655A2 (en) 2003-10-22

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase