AU2002231328A1 - Radiopharmaceutical formulations - Google Patents

Radiopharmaceutical formulations

Info

Publication number
AU2002231328A1
AU2002231328A1 AU2002231328A AU3132802A AU2002231328A1 AU 2002231328 A1 AU2002231328 A1 AU 2002231328A1 AU 2002231328 A AU2002231328 A AU 2002231328A AU 3132802 A AU3132802 A AU 3132802A AU 2002231328 A1 AU2002231328 A1 AU 2002231328A1
Authority
AU
Australia
Prior art keywords
radiopharmaceutical
radiopharmaceuticals
preparation
radiopharmaceutical formulations
formulations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002231328A
Inventor
Aldo Cagnolini
Karen E. Linder
Edmund R. Marinelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco Research USA Inc
Original Assignee
Bracco Research USA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Research USA Inc filed Critical Bracco Research USA Inc
Publication of AU2002231328A1 publication Critical patent/AU2002231328A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3

Abstract

A method is described for inhibiting the degradation of a diagnostic or radiotherapeutic radiopharmaceutical, especially radiolabeled compounds containing reducible moieties, by including oxidants either as a part of the composition for the preparation of such radiopharmaceuticals, or by adding an oxidant to such compositions immediately after the preparation of such radiopharmaceuticals.
AU2002231328A 2000-10-19 2001-10-19 Radiopharmaceutical formulations Abandoned AU2002231328A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24178200P 2000-10-19 2000-10-19
US60241782 2000-10-19
US60/241,782 2000-10-19
PCT/US2001/050802 WO2002032294A2 (en) 2000-10-19 2001-10-19 Radiopharmaceutical formulations

Publications (1)

Publication Number Publication Date
AU2002231328A1 true AU2002231328A1 (en) 2002-04-29

Family

ID=22912151

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002231328A Abandoned AU2002231328A1 (en) 2000-10-19 2001-10-19 Radiopharmaceutical formulations

Country Status (7)

Country Link
US (1) US20050074402A1 (en)
EP (1) EP1404376B1 (en)
AT (1) ATE445418T1 (en)
AU (1) AU2002231328A1 (en)
CA (1) CA2426584C (en)
DE (1) DE60140219D1 (en)
WO (1) WO2002032294A2 (en)

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US8489176B1 (en) 2000-08-21 2013-07-16 Spectrum Dynamics Llc Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
US8565860B2 (en) 2000-08-21 2013-10-22 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system
US8909325B2 (en) 2000-08-21 2014-12-09 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
US20040204646A1 (en) * 2002-11-04 2004-10-14 V-Target Technologies Ltd. Intracorporeal-imaging head
WO2006054296A2 (en) * 2004-11-17 2006-05-26 Spectrum Dynamics Llc Methods of detecting prostate cancer
US8571881B2 (en) 2004-11-09 2013-10-29 Spectrum Dynamics, Llc Radiopharmaceutical dispensing, administration, and imaging
US9470801B2 (en) 2004-01-13 2016-10-18 Spectrum Dynamics Llc Gating with anatomically varying durations
US9040016B2 (en) 2004-01-13 2015-05-26 Biosensors International Group, Ltd. Diagnostic kit and methods for radioimaging myocardial perfusion
US7176466B2 (en) 2004-01-13 2007-02-13 Spectrum Dynamics Llc Multi-dimensional image reconstruction
US7968851B2 (en) 2004-01-13 2011-06-28 Spectrum Dynamics Llc Dynamic spect camera
WO2007010534A2 (en) 2005-07-19 2007-01-25 Spectrum Dynamics Llc Imaging protocols
US8586932B2 (en) * 2004-11-09 2013-11-19 Spectrum Dynamics Llc System and method for radioactive emission measurement
EP1778957A4 (en) 2004-06-01 2015-12-23 Biosensors Int Group Ltd Radioactive-emission-measurement optimization to specific body structures
US20060051731A1 (en) * 2004-08-12 2006-03-09 David Ho Processes for preparing lyophilized platelets
EP1784639B1 (en) 2004-08-12 2010-01-20 CELLPHIRE, Inc. Methods for preparing freeze-dried platelets, compositions comprising freeze-dried platelets, and methods of use
US7811558B2 (en) * 2004-08-12 2010-10-12 Cellphire, Inc. Use of stabilized platelets as hemostatic agent
US20060035383A1 (en) * 2004-08-12 2006-02-16 David Ho Dry platelet preparations for use in diagnostics
US9943274B2 (en) 2004-11-09 2018-04-17 Spectrum Dynamics Medical Limited Radioimaging using low dose isotope
US8423125B2 (en) * 2004-11-09 2013-04-16 Spectrum Dynamics Llc Radioimaging
US9316743B2 (en) 2004-11-09 2016-04-19 Biosensors International Group, Ltd. System and method for radioactive emission measurement
EP1827505A4 (en) * 2004-11-09 2017-07-12 Biosensors International Group, Ltd. Radioimaging
US8615405B2 (en) 2004-11-09 2013-12-24 Biosensors International Group, Ltd. Imaging system customization using data from radiopharmaceutical-associated data carrier
WO2008059489A2 (en) * 2006-11-13 2008-05-22 Spectrum Dynamics Llc Radioimaging applications of and novel formulations of teboroxime
US8837793B2 (en) 2005-07-19 2014-09-16 Biosensors International Group, Ltd. Reconstruction stabilizer and active vision
US8894974B2 (en) 2006-05-11 2014-11-25 Spectrum Dynamics Llc Radiopharmaceuticals for diagnosis and therapy
US8097403B2 (en) * 2006-12-14 2012-01-17 Cellphire, Inc. Freeze-dried platelets, method of making and method of use as a diagnostic agent
WO2008075362A2 (en) * 2006-12-20 2008-06-26 Spectrum Dynamics Llc A method, a system, and an apparatus for using and processing multidimensional data
US8521253B2 (en) 2007-10-29 2013-08-27 Spectrum Dynamics Llc Prostate imaging
US8338788B2 (en) 2009-07-29 2012-12-25 Spectrum Dynamics Llc Method and system of optimized volumetric imaging
US20110183311A1 (en) * 2010-01-27 2011-07-28 David Ho Dry platelet preparations for use in diagnostics
WO2020112963A1 (en) 2018-11-30 2020-06-04 Cellphire, Inc. Platelets as delivery agents
WO2020113090A1 (en) 2018-11-30 2020-06-04 Cellphire, Inc. Platelets as delivery agents
WO2020227149A1 (en) 2019-05-03 2020-11-12 Cellphire, Inc. Materials and methods for producing blood products
CA3150936A1 (en) 2019-08-16 2021-02-25 Cellphire, Inc. Thrombosomes as an antiplatelet agent reversal agent
US11903971B2 (en) 2020-02-04 2024-02-20 Cellphire, Inc. Treatment of von Willebrand disease

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US4229427A (en) * 1978-06-28 1980-10-21 The Procter & Gamble Company Radioactive scanning agents with hydroquinone stabilizer
US4208340A (en) * 1978-10-30 1980-06-17 Standard Oil Company (Indiana) Substituted ortho-quinones and derivatives
US4427647A (en) 1980-08-12 1984-01-24 Amersham International Limited Method and reagent for making a radiopharmaceutical composition based on pertechnetate
DE78642T1 (en) * 1981-10-30 1983-10-27 Amersham International Plc, Amersham, Buckinghamshire RADIOPHARMACEUTICAL PREPARATION BASED ON TECHNETIUM-99M AND REAGENT FOR THE PRODUCTION THEREOF.
US4707353A (en) * 1982-12-08 1987-11-17 Mallinckrodt, Inc. Radiographic imaging agents
DE3323375A1 (en) 1983-06-29 1985-01-03 Hoechst Ag, 6230 Frankfurt N-(4-Aminobenzoyl)aminoacetic acid for the stabilisation of technetium-99m products, stabilised injection products and process for the preparation thereof
EP0313712B1 (en) 1987-10-30 1992-07-29 SORIN BIOMEDICA S.p.A. Stable radiodiagnostic compositons and their preparation
US4880615A (en) * 1988-11-25 1989-11-14 Merck & Co., Inc. Stabilized radiopharmaceutical compositions
GB8910779D0 (en) 1989-05-10 1989-06-28 Solanki Kishor K Stabilisation of radiopharmaceutical compositions
US5262175A (en) * 1989-05-10 1993-11-16 Solanki Kishor K Stabilization of radiopharmaceutical compositions
US5219556A (en) * 1990-07-09 1993-06-15 Mallinckrodt Medical, Inc. Stabilized therapeutic radiopharmaceutical complexes
US5093105A (en) * 1991-04-09 1992-03-03 Merck Frosst Canada, Inc. Radiopharmaceutical bacteriostats
US5686058A (en) * 1992-04-30 1997-11-11 Amersham International Plc Radiolabelled nucleotide formulations stored in an unfrozen state
US5318993A (en) * 1993-04-16 1994-06-07 Bristol-Myers Squibb Company Antihyperlipidemic benzoquinones
US5605672A (en) * 1993-06-09 1997-02-25 The General Hospital Corporation Blood pool imaging composition and method of its use
US5608110A (en) * 1993-06-15 1997-03-04 Bracco International B.V. Heteroatom-bearing ligands and metal complexes thereof
US7112671B2 (en) * 2000-08-30 2006-09-26 Pharmacyclics, Inc. Non-symmetric tripyrranes in the synthesis of novel macrocycles
US20020187099A1 (en) 2001-05-16 2002-12-12 Rajesh Manchanda Stabilization of radionuclide-containing compositions

Also Published As

Publication number Publication date
WO2002032294A3 (en) 2002-07-11
EP1404376A4 (en) 2007-07-04
US20050074402A1 (en) 2005-04-07
ATE445418T1 (en) 2009-10-15
WO2002032294A2 (en) 2002-04-25
EP1404376B1 (en) 2009-10-14
EP1404376A2 (en) 2004-04-07
DE60140219D1 (en) 2009-11-26
CA2426584C (en) 2010-08-10
CA2426584A1 (en) 2002-04-25

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