AU2002224402A1 - Substituted imidazoles useful in the treatment of inflammatory diseases - Google Patents

Substituted imidazoles useful in the treatment of inflammatory diseases

Info

Publication number
AU2002224402A1
AU2002224402A1 AU2002224402A AU2440202A AU2002224402A1 AU 2002224402 A1 AU2002224402 A1 AU 2002224402A1 AU 2002224402 A AU2002224402 A AU 2002224402A AU 2440202 A AU2440202 A AU 2440202A AU 2002224402 A1 AU2002224402 A1 AU 2002224402A1
Authority
AU
Australia
Prior art keywords
treatment
substituted imidazoles
inflammatory diseases
useful
imidazoles useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002224402A
Inventor
Scott Beers
Michael P. Wachter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
Ortho McNeil Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc
Publication of AU2002224402A1 publication Critical patent/AU2002224402A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

This invention relates to substituted imidazoles of Formula I pharmaceutical compositions containing them, methods of using them and intermediates useful in their manufacture. The compounds of the invention modulate the production of a number of inflammatory cytokines and are useful in the treatment of diseases associated with the overproduction of inflammatory cytokines.
AU2002224402A 2000-10-18 2001-10-17 Substituted imidazoles useful in the treatment of inflammatory diseases Abandoned AU2002224402A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24125600P 2000-10-18 2000-10-18
US60241256 2000-10-18
PCT/US2001/032436 WO2002032894A1 (en) 2000-10-18 2001-10-17 Substituted imidazoles useful in the treatment of inflammatory diseases

Publications (1)

Publication Number Publication Date
AU2002224402A1 true AU2002224402A1 (en) 2002-04-29

Family

ID=22909922

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002224402A Abandoned AU2002224402A1 (en) 2000-10-18 2001-10-17 Substituted imidazoles useful in the treatment of inflammatory diseases

Country Status (8)

Country Link
US (1) US7041686B2 (en)
EP (1) EP1337526B1 (en)
JP (1) JP2004511554A (en)
AT (1) ATE297392T1 (en)
AU (1) AU2002224402A1 (en)
CA (1) CA2426337A1 (en)
DE (1) DE60111417T2 (en)
WO (1) WO2002032894A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA80295C2 (en) 2002-09-06 2007-09-10 Biogen Inc Pyrazolopyridines and using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0830063B2 (en) * 1986-11-18 1996-03-27 富山化学工業株式会社 Novel imidazole derivative and its salt
MX9300141A (en) 1992-01-13 1994-07-29 Smithkline Beecham Corp NOVEL IMIDAZOLE COMPOUNDS, PROCEDURE FOR THE PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT.
KR100568438B1 (en) * 1997-04-24 2006-04-07 오르토-맥네일 파마슈티칼, 인코퍼레이티드 Substituted imidazoles useful in the treatment of inflammatory diseases, a process for the preparation thereof and pharmaceutical compositions containing the same
IL133766A0 (en) 1997-06-30 2001-04-30 Ortho Mcneil Pharm Inc 2-substituted imidazoles useful in the treatment of inflammatory diseases
AU3111700A (en) * 1998-12-04 2000-06-19 Structural Bioinformatics Inc. Methods and compositions for treating inflammatory diseases utilizing inhibitorsof tumor necrosis factor activity

Also Published As

Publication number Publication date
DE60111417D1 (en) 2005-07-14
DE60111417T2 (en) 2006-03-16
EP1337526A1 (en) 2003-08-27
JP2004511554A (en) 2004-04-15
ATE297392T1 (en) 2005-06-15
EP1337526B1 (en) 2005-06-08
US7041686B2 (en) 2006-05-09
US20040214816A1 (en) 2004-10-28
WO2002032894A1 (en) 2002-04-25
CA2426337A1 (en) 2002-04-25

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