AU2002222748A1 - Novel use of diterpene compound as a therapeutic agent of inflammation, immune disease or cancer - Google Patents

Novel use of diterpene compound as a therapeutic agent of inflammation, immune disease or cancer

Info

Publication number
AU2002222748A1
AU2002222748A1 AU2002222748A AU2274802A AU2002222748A1 AU 2002222748 A1 AU2002222748 A1 AU 2002222748A1 AU 2002222748 A AU2002222748 A AU 2002222748A AU 2274802 A AU2274802 A AU 2274802A AU 2002222748 A1 AU2002222748 A1 AU 2002222748A1
Authority
AU
Australia
Prior art keywords
inflammation
cancer
therapeutic agent
immune disease
novel use
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002222748A
Inventor
Young-Soo Hong
Bang-Yeon Hwang
Hang-Sub Kim
Jeong-Hyung Lee
Jung-Joon Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Korea Research Institute of Bioscience and Biotechnology KRIBB
Original Assignee
Korea Research Institute of Bioscience and Biotechnology KRIBB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Research Institute of Bioscience and Biotechnology KRIBB filed Critical Korea Research Institute of Bioscience and Biotechnology KRIBB
Publication of AU2002222748A1 publication Critical patent/AU2002222748A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/743—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups having unsaturation outside the rings, e.g. humulones, lupulones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002222748A 2000-12-12 2001-12-12 Novel use of diterpene compound as a therapeutic agent of inflammation, immune disease or cancer Abandoned AU2002222748A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2000-0075608A KR100383149B1 (en) 2000-12-12 2000-12-12 A novel use of diterpene compounds as therapeutic agents of inflammation, immune disease and cancer
KR0075608 2000-12-12
PCT/KR2001/002152 WO2002047675A1 (en) 2000-12-12 2001-12-12 Novel use of diterpene compound as a therapeutic agent of inflammation, immune disease or cancer

Publications (1)

Publication Number Publication Date
AU2002222748A1 true AU2002222748A1 (en) 2002-06-24

Family

ID=19702988

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002222748A Abandoned AU2002222748A1 (en) 2000-12-12 2001-12-12 Novel use of diterpene compound as a therapeutic agent of inflammation, immune disease or cancer

Country Status (4)

Country Link
US (1) US6894073B2 (en)
KR (1) KR100383149B1 (en)
AU (1) AU2002222748A1 (en)
WO (1) WO2002047675A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100521844B1 (en) * 2002-10-02 2005-10-17 주식회사 팜트리 Pharmaceutical compositions for the inhibition of angiogenesis containing the derivatives of diterpene compound
CN100345810C (en) * 2003-06-30 2007-10-31 桂明玉 Novel natural drug effective region of rabdosiaexcisa total diterpene
MXPA06013503A (en) 2004-05-19 2007-06-12 Tan Wen The use of kauranes compounds in the manufacture of medicament.
US8911438B2 (en) * 2004-08-10 2014-12-16 Medtronic, Inc. Tuna device with integrated saline reservoir
ES2731298T3 (en) 2005-05-27 2019-11-14 Univ North Carolina Chapel Hill Nitric oxide release particles for nitric oxide therapeutic agents and biomedical applications
CN101003528B (en) * 2006-01-18 2010-05-26 郑州大学 Diterpene compound and derivative in kaurene class of new dissymmetry, and its preparation method and uses
CN101357883B (en) * 2007-07-30 2012-09-26 国鼎生物科技股份有限公司 Antrodia camphoratea pimelie kelone compound for treating autoimmune disease and medicine composition
ES2958410T3 (en) 2009-08-21 2024-02-08 Novan Inc Topical gels
CN102695528B (en) 2009-08-21 2016-07-13 诺万公司 Wound dressing, its using method and forming method thereof
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
EP2681286B1 (en) 2011-02-28 2018-08-15 Novan, Inc. Nitric oxide-releasing s-nitrosothiol-modified silica particles and methods of making the same
CN105837550B (en) * 2015-11-19 2018-02-16 中国科学院昆明植物研究所 Natural asymmetric New cyclobutane derivative and its pharmaceutical composition
CN105461732A (en) * 2016-01-04 2016-04-06 范素琴 Novel diterpenoid compound and preparation method and medical application thereof
CN107501097B (en) * 2017-08-16 2020-06-16 河南中医药大学 Preparation method and application of a pair of novel compounds extracted from Rabdosia trichocarpa and having antitumor activity
CN113262215B (en) * 2020-02-15 2023-06-02 东莞市凯法生物医药有限公司 Application of kaurane compounds in preparation of medicines for preventing and treating sepsis and multi-organ injury
CN113616639A (en) * 2021-09-03 2021-11-09 西北师范大学 Application of ent-kaurane diterpene kamebacetal A in preparation of medicine for treating lung cancer
CN114591269B (en) * 2022-03-21 2022-12-13 中南民族大学 Eremophilane type sesquiterpene and application thereof in preparation of drugs with anti-inflammatory activity
CN114805269B (en) * 2022-04-08 2023-09-15 中国科学院昆明植物研究所 Eriocalyxin B derivative and application thereof in preparation of antitumor drugs
CN114890971B (en) * 2022-04-08 2023-09-15 中国科学院昆明植物研究所 Eriocalyxin B derivative, pharmaceutical composition thereof and application of eriocalyxin B derivative in resisting new coronatine pneumonia
CN115806491B (en) * 2022-12-13 2024-05-03 沈阳药科大学 Terpenoid with nerve cell protection in corn silk and preparation method and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57167938A (en) * 1981-04-07 1982-10-16 Taiho Yakuhin Kogyo Kk Novel diterpenoid
US5248696A (en) * 1991-04-18 1993-09-28 World Research Institute For Science And Technology, Inc. Composition and method for treating tumors
JPH0987189A (en) 1995-09-19 1997-03-31 Ichimaru Pharcos Co Ltd Antiallergic agent containing isodon japonicus hara, paeonia suffruticosa andrews, perilla frutescens britton var. acuta kudo, and/or arunica montana linne
ES2211030T3 (en) * 1998-01-26 2004-07-01 Sae Han Pharm. Co., Ltd. DITERPEN DERIVATIVES AND ANTI-INFLAMMATORY ANALGESIC AGENTS THAT UNDERSTAND THE SAME.

Also Published As

Publication number Publication date
KR100383149B1 (en) 2003-05-12
US20040048918A1 (en) 2004-03-11
KR20020046095A (en) 2002-06-20
US6894073B2 (en) 2005-05-17
WO2002047675A1 (en) 2002-06-20

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