AU2002218019A1 - Methods for depleting and isolating alloreactive and antigen-reactive t cells from hematopoietic donor cells - Google Patents
Methods for depleting and isolating alloreactive and antigen-reactive t cells from hematopoietic donor cellsInfo
- Publication number
- AU2002218019A1 AU2002218019A1 AU2002218019A AU1801902A AU2002218019A1 AU 2002218019 A1 AU2002218019 A1 AU 2002218019A1 AU 2002218019 A AU2002218019 A AU 2002218019A AU 1801902 A AU1801902 A AU 1801902A AU 2002218019 A1 AU2002218019 A1 AU 2002218019A1
- Authority
- AU
- Australia
- Prior art keywords
- cells
- alloreactive
- depleting
- antigen
- isolating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0081—Purging biological preparations of unwanted cells
- C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Transplantation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70633700A | 2000-11-03 | 2000-11-03 | |
US09/706,337 | 2000-11-03 | ||
PCT/US2001/046333 WO2002036748A2 (en) | 2000-11-03 | 2001-10-31 | Methods for depleting and isolating alloreactive and antigen-reactive t cells from hematopoietic donor cells |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2002218019A1 true AU2002218019A1 (en) | 2002-05-15 |
Family
ID=24837124
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002218019A Abandoned AU2002218019A1 (en) | 2000-11-03 | 2001-10-31 | Methods for depleting and isolating alloreactive and antigen-reactive t cells from hematopoietic donor cells |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2002218019A1 (en) |
WO (1) | WO2002036748A2 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005506372A (en) * | 2001-10-24 | 2005-03-03 | ザ コーポレーション オブ ザ トラスティーズ オブ ザ オーダー オブ ザ シスターズ オブ メルシー イン クィーンズランド | Methods for modulating immune activity of immunoresponsive grafts by progenipoietin |
US7332158B2 (en) | 2002-05-29 | 2008-02-19 | Demao Yang | Compositions and treatments for myelosuppression by ex vivo activated immune cells |
US7048922B2 (en) | 2002-05-29 | 2006-05-23 | Demao Yang | Stimulation of hematopoiesis by ex vivo activated immune cells |
EP1638993A4 (en) * | 2003-06-10 | 2007-05-09 | Univ Melbourne | Immunomodulating compositions, uses therefor and processes for their production |
AU2008301240B2 (en) | 2007-09-20 | 2014-07-31 | St Vincent's Hospital Sydney Limited | A method for identifying antigen-specific regulatory T cells |
WO2016176193A1 (en) * | 2015-04-27 | 2016-11-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Method for the selective depletion of alloreactive t lymphocytes from donor stem cell or lymphocyte grafts to prevent graft-versus-host disease |
CN109666640B (en) * | 2019-01-14 | 2020-06-16 | 武汉睿健医药科技有限公司 | Method for pure culture of natural killer cells in vitro |
US20230079454A1 (en) * | 2020-02-14 | 2023-03-16 | The General Hospital Corporation | Monitoring viability of organs for transplantation |
WO2023006982A1 (en) * | 2021-07-29 | 2023-02-02 | Transimmune Ag | Methods for selectively reducing immunogenicity in a transplant |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1005531A2 (en) * | 1997-07-21 | 2000-06-07 | Cerus Corporation | Method of treating leukocytes, leukocyte compositions and methods of use thereof |
WO1999005174A1 (en) * | 1997-07-23 | 1999-02-04 | Rijksuniversiteit Te Leiden | The ha-1 antigen |
ATE428769T1 (en) * | 1997-10-27 | 2009-05-15 | Univ Rockefeller | METHOD AND COMPOSITION FOR PRODUCING MATURE DENDRITIC CELLS |
ATE406178T1 (en) * | 1997-11-12 | 2008-09-15 | Univ Pennsylvania | PREVENTION OF IMMUNOREACTIVITY THROUGH DEPUPPERATION OR INHIBITION OF ANTIGEN-PRESENTING CELLS |
JP2004510950A (en) * | 1998-06-30 | 2004-04-08 | ザ ロックフェラー ユニバーシティ | Methods and Agents for Detection and Modulation of Cellular Immunity to Immunoimmune Antigens |
AU1337801A (en) * | 1999-10-22 | 2001-05-08 | Biotransplant Incorporated | Process for inducing immunological tolerance for xenogeneic transplants |
-
2001
- 2001-10-31 AU AU2002218019A patent/AU2002218019A1/en not_active Abandoned
- 2001-10-31 WO PCT/US2001/046333 patent/WO2002036748A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2002036748A2 (en) | 2002-05-10 |
WO2002036748A3 (en) | 2003-10-02 |
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