AU2002216341A1 - The use of ecm degrading enzymes for the improvement of cell transplantation - Google Patents
The use of ecm degrading enzymes for the improvement of cell transplantationInfo
- Publication number
- AU2002216341A1 AU2002216341A1 AU2002216341A AU1634102A AU2002216341A1 AU 2002216341 A1 AU2002216341 A1 AU 2002216341A1 AU 2002216341 A AU2002216341 A AU 2002216341A AU 1634102 A AU1634102 A AU 1634102A AU 2002216341 A1 AU2002216341 A1 AU 2002216341A1
- Authority
- AU
- Australia
- Prior art keywords
- improvement
- cell transplantation
- degrading enzymes
- ecm degrading
- ecm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/0105—Alpha-N-acetylglucosaminidase (3.2.1.50)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01035—Hyaluronoglucosaminidase (3.2.1.35), i.e. hyaluronidase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01128—Glycyrrhizinate beta-glucuronidase (3.2.1.128), i.e. GL beta-D-glucoronidase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01166—Heparanase (3.2.1.166)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25634700P | 2000-12-19 | 2000-12-19 | |
US60/256,347 | 2000-12-19 | ||
PCT/IL2001/001169 WO2002050243A2 (en) | 2000-12-19 | 2001-12-17 | The use of ecm degrading enzymes for the improvement of cell transplantation |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2002216341A1 true AU2002216341A1 (en) | 2002-07-01 |
Family
ID=22971908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002216341A Abandoned AU2002216341A1 (en) | 2000-12-19 | 2001-12-17 | The use of ecm degrading enzymes for the improvement of cell transplantation |
Country Status (6)
Country | Link |
---|---|
US (1) | US20040033218A1 (en) |
EP (1) | EP1379139A4 (en) |
JP (1) | JP2005500977A (en) |
AU (1) | AU2002216341A1 (en) |
CA (1) | CA2432157A1 (en) |
WO (1) | WO2002050243A2 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070053884A1 (en) * | 2003-05-16 | 2007-03-08 | Kyowa Hakko Kogyo Co., Ltd | Novel adult tissue-derived stem cell and use thereof |
CA2594013A1 (en) * | 2005-01-12 | 2006-07-20 | Massachusetts Institute Of Technology | Methods and compositions related to modulating the extracellular stem cell environment |
WO2008124494A1 (en) * | 2007-04-03 | 2008-10-16 | The Cleveland Clinic Foundation | Enrichment of tissue-derived adult stem cells based on retained extracellular matrix material |
US20160017302A1 (en) * | 2013-03-05 | 2016-01-21 | Baylor College Of Medicine | Heparanase expression in human t lymphocytes |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5061620A (en) * | 1990-03-30 | 1991-10-29 | Systemix, Inc. | Human hematopoietic stem cell |
US6153187A (en) * | 1997-09-02 | 2000-11-28 | Insight Strategy & Marketing Ltd. | Use of glycosaminoglycans degrading enzymes for management of airway associated diseases |
US6177545B1 (en) * | 1997-09-02 | 2001-01-23 | Insight Strategy & Marketing Ltd. | Heparanase specific molecular probes and their use in research and medical applications |
US5968822A (en) * | 1997-09-02 | 1999-10-19 | Pecker; Iris | Polynucleotide encoding a polypeptide having heparanase activity and expression of same in transduced cells |
US6348344B1 (en) * | 1997-09-02 | 2002-02-19 | Insight Strategy & Marketing Ltd. | Genetically modified cells and methods for expressing recombinant heparanase and methods of purifying same |
US20010006630A1 (en) * | 1997-09-02 | 2001-07-05 | Oron Yacoby-Zeevi | Introducing a biological material into a patient |
US6190875B1 (en) * | 1997-09-02 | 2001-02-20 | Insight Strategy & Marketing Ltd. | Method of screening for potential anti-metastatic and anti-inflammatory agents using mammalian heparanase as a probe |
BR9813296A (en) * | 1997-10-28 | 2000-08-22 | Univ Australian | Isolated nucleic acid molecule, process for identifying a nucleic acid molecule encoding a mammalian endoglucuronidase polypeptide, expression vector, isolated heparanase peptide, recombinant or isolated polypeptide, antibody molecule, process for identifying a modulator of heparanase activity, use of a sulfated oligosaccharide, a sulfonate or hspg comprising the same, processes for treating a physiological or medical condition in a human or animal subject in which the heparanase activity in that subject is high, to intensify the healing of wounds in a subject human or animal and to diagnose a physiological or medical condition associated with overexpression of heparanase, e, cell |
AU1864999A (en) * | 1997-12-15 | 1999-07-05 | Universite Laval | Methods and compositions for improving the success of cell transplantation in a host |
WO2000052178A1 (en) * | 1999-03-01 | 2000-09-08 | Insight Strategy & Marketing Ltd. | Polynucleotide encoding a polypeptide having heparanase activity and expression of same in genetically modified cells |
EP1333862A4 (en) * | 2000-10-17 | 2004-08-18 | Insight Strategy & Marketing | Methods of and pharmaceutical compositions for improving implantation of embryos |
-
2001
- 2001-12-17 US US10/450,195 patent/US20040033218A1/en not_active Abandoned
- 2001-12-17 AU AU2002216341A patent/AU2002216341A1/en not_active Abandoned
- 2001-12-17 WO PCT/IL2001/001169 patent/WO2002050243A2/en not_active Application Discontinuation
- 2001-12-17 EP EP01271434A patent/EP1379139A4/en not_active Withdrawn
- 2001-12-17 JP JP2002552120A patent/JP2005500977A/en active Pending
- 2001-12-17 CA CA002432157A patent/CA2432157A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2002050243A3 (en) | 2003-10-30 |
JP2005500977A (en) | 2005-01-13 |
WO2002050243A2 (en) | 2002-06-27 |
EP1379139A2 (en) | 2004-01-14 |
US20040033218A1 (en) | 2004-02-19 |
CA2432157A1 (en) | 2002-06-27 |
EP1379139A4 (en) | 2004-12-01 |
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