US20040102389A1
(en)
*
|
1995-10-26 |
2004-05-27 |
Ribozyme Pharmaceuticals, Inc. |
Nucleic acid-mediated treatment of diseases or conditions related to levels of vascular endothelial growth factor receptor (VEGF-R)
|
US20040198682A1
(en)
*
|
2001-11-30 |
2004-10-07 |
Mcswiggen James |
RNA interference mediated inhibition of placental growth factor gene expression using short interfering nucleic acid (siNA)
|
US20050148530A1
(en)
*
|
2002-02-20 |
2005-07-07 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US20050054596A1
(en)
*
|
2001-11-30 |
2005-03-10 |
Mcswiggen James |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US20040138163A1
(en)
*
|
2002-05-29 |
2004-07-15 |
Mcswiggen James |
RNA interference mediated inhibition of vascular edothelial growth factor and vascular edothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US20070203333A1
(en)
*
|
2001-11-30 |
2007-08-30 |
Mcswiggen James |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US20050075304A1
(en)
*
|
2001-11-30 |
2005-04-07 |
Mcswiggen James |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
EP1474450A2
(en)
*
|
2002-02-08 |
2004-11-10 |
Vlaams Interuniversitair Instituut voor Biotechnologie vzw. |
A novel target to inhibit angiogenesis
|
EP2305813A3
(en)
*
|
2002-11-14 |
2012-03-28 |
Dharmacon, Inc. |
Fuctional and hyperfunctional sirna
|
WO2006006948A2
(en)
|
2002-11-14 |
2006-01-19 |
Dharmacon, Inc. |
METHODS AND COMPOSITIONS FOR SELECTING siRNA OF IMPROVED FUNCTIONALITY
|
WO2006110813A2
(en)
|
2005-04-12 |
2006-10-19 |
Intradigm Corporation |
Composition and methods of rnai therapeutics for treatment of cancer and other neovascularization diseases
|
US8288354B2
(en)
|
2005-12-28 |
2012-10-16 |
The Scripps Research Institute |
Natural antisense and non-coding RNA transcripts as drug targets
|
JP2011500023A
(en)
*
|
2007-10-12 |
2011-01-06 |
イントラダイム コーポレイション |
Therapeutic siRNA molecules for reducing VEGFR1 expression in vitro and in vivo
|
JP2011526892A
(en)
|
2008-06-30 |
2011-10-20 |
アンジオブラスト システムズ,インコーポレーテッド |
Treatment of ocular diseases and hypervascularization using combination therapy
|
EP2352830B1
(en)
|
2008-10-03 |
2019-01-16 |
CuRNA, Inc. |
Treatment of apolipoprotein-a1 related diseases by inhibition of natural antisense transcript to apolipoprotein-a1
|
CA2745329C
(en)
|
2008-12-04 |
2022-07-12 |
Opko Curna, Llc |
Treatment of erythropoietin (epo) related diseases by inhibition of natural antisense transcript to epo
|
KR20110091796A
(en)
|
2008-12-04 |
2011-08-12 |
오피케이오 큐알엔에이, 엘엘씨 |
Treatment of tumor suppressor gene related diseases by inhibition of natural antisense transcript to the gene
|
WO2010065671A2
(en)
|
2008-12-04 |
2010-06-10 |
Curna, Inc. |
Treatment of vascular endothelial growth factor (vegf) related diseases by inhibition of natural antisense transcript to vegf
|
EP2396038B1
(en)
|
2009-02-12 |
2015-10-21 |
CuRNA, Inc. |
Treatment of brain derived neurotrophic factor (bdnf) related diseases by inhibition of natural antisense transcript to bdnf
|
ES2656290T3
(en)
|
2009-03-16 |
2018-02-26 |
Curna, Inc. |
Treatment of diseases related to nuclear factor (derived from erythroid 2) similar to 2 (NRF2) by inhibition of natural antisense transcript to NRF2
|
CA2755404C
(en)
|
2009-03-17 |
2020-03-24 |
Joseph Collard |
Treatment of delta-like 1 homolog (dlk1) related diseases by inhibition of natural antisense transcript to dlk1
|
CN106237345A
(en)
|
2009-05-06 |
2016-12-21 |
库尔纳公司 |
By suppression therapy lipid transfer and the metabolic gene relevant disease of the natural antisense transcript for lipid transfer and metabolic gene
|
ES2609655T3
(en)
|
2009-05-06 |
2017-04-21 |
Curna, Inc. |
Treatment of diseases related to tristetraproline (TTP) by inhibition of natural antisense transcript for TTP
|
CA3185821A1
(en)
|
2009-05-08 |
2010-11-11 |
Curna, Inc. |
Treatment of dystrophin family related diseases by inhibition of natural antisense transcript to dmd family
|
EP2432881B1
(en)
|
2009-05-18 |
2017-11-15 |
CuRNA, Inc. |
Treatment of reprogramming factor related diseases by inhibition of natural antisense transcript to a reprogramming factor
|
KR101703695B1
(en)
|
2009-05-22 |
2017-02-08 |
큐알엔에이, 인크. |
Treatment of transcription factor e3 (tfe3) and insulin receptor substrate 2 (irs2) related diseases by inhibition of natural antisense transcript to tfe3
|
US8791085B2
(en)
|
2009-05-28 |
2014-07-29 |
Curna, Inc. |
Treatment of antiviral gene related diseases by inhibition of natural antisense transcript to an antiviral gene
|
KR101801404B1
(en)
|
2009-06-16 |
2017-12-20 |
큐알엔에이, 인크. |
Treatment of collagen gene related diseases by inhibition of natural antisense transcript to a collagen gene
|
EP2443238B1
(en)
|
2009-06-16 |
2017-03-22 |
CuRNA, Inc. |
Treatment of paraoxonase 1 (pon1) related diseases by inhibition of natural antisense transcript to pon1
|
JP6073133B2
(en)
|
2009-06-24 |
2017-02-01 |
クルナ・インコーポレーテッド |
Treatment of TNFR2-related diseases by suppression of natural antisense transcripts against tumor necrosis factor receptor 2 (TNFR2)
|
US8921330B2
(en)
|
2009-06-26 |
2014-12-30 |
Curna, Inc. |
Treatment of down syndrome gene related diseases by inhibition of natural antisense transcript to a down syndrome gene
|
WO2011011700A2
(en)
|
2009-07-24 |
2011-01-27 |
Curna, Inc. |
Treatment of sirtuin (sirt) related diseases by inhibition of natural antisense transcript to a sirtuin (sirt)
|
WO2011017516A2
(en)
|
2009-08-05 |
2011-02-10 |
Curna, Inc. |
Treatment of insulin gene (ins) related diseases by inhibition of natural antisense transcript to an insulin gene (ins)
|
ES2599986T3
(en)
|
2009-08-11 |
2017-02-06 |
Curna, Inc. |
Treatment of adiponectin-related diseases (ADIPOQ) by inhibiting a natural antisense transcript of an adiponectin (ADIPOQ)
|
CN102482670B
(en)
|
2009-08-21 |
2018-06-15 |
库尔纳公司 |
CHIP relevant diseases are treated by inhibiting the natural antisense transcript of ' C-terminal of HSP70- interaction proteins ' (CHIP)
|
KR101892760B1
(en)
|
2009-08-25 |
2018-08-28 |
큐알엔에이, 인크. |
Treatment of 'iq motif containing gtpase activating protein' (iqgap) related diseases by inhibition of natural antisense transcript to iqgap
|
NO2480669T3
(en)
|
2009-09-25 |
2018-04-07 |
|
|
KR101823702B1
(en)
|
2009-12-16 |
2018-01-30 |
큐알엔에이, 인크. |
Treatment of membrane bound transcription factor peptidase, site 1 (mbtps1) related diseases by inhibition of natural antisense transcript to mbtps1
|
CN102781480B
(en)
|
2009-12-23 |
2018-07-27 |
库尔纳公司 |
UCP2 relevant diseases are treated by inhibiting the natural antisense transcript of uncoupling protein-3 (UCP2)
|
ES2661387T3
(en)
|
2009-12-23 |
2018-03-28 |
Curna, Inc. |
Treatment of diseases related to hepatocyte growth factor (hgf) by inhibition of the natural antisense transcript to hgf
|
CA2785173A1
(en)
|
2009-12-29 |
2011-07-28 |
Curna, Inc. |
Treatment of nuclear respiratory factor 1 (nrf1) related diseases by inhibition of natural antisense transcript to nrf1
|
CN102770540B
(en)
|
2009-12-29 |
2017-06-23 |
库尔纳公司 |
P63 relevant diseases are treated by suppressing the natural antisense transcript of oncoprotein 63 (p63)
|
ES2677044T3
(en)
|
2009-12-31 |
2018-07-27 |
Curna, Inc. |
Treatment of diseases related to insulin receptor substrate 2 (IRS2) by inhibition of natural antisense transcript for IRS2 and transcription factor E3 (TFE3)
|
CA2785832A1
(en)
|
2010-01-04 |
2011-07-07 |
Curna, Inc. |
Treatment of interferon regulatory factor 8 (irf8) related diseases by inhibition of natural antisense transcript to irf8
|
KR101853509B1
(en)
|
2010-01-06 |
2018-04-30 |
큐알엔에이, 인크. |
Treatment of Pancreatic Developmental Gene Related Diseases By Inhibition of Natural Antisense Transcript to A Pancreatic Developmental Gene
|
NO2524039T3
(en)
|
2010-01-11 |
2018-04-28 |
|
|
JP5981850B2
(en)
|
2010-01-25 |
2016-08-31 |
カッパーアールエヌエー,インコーポレイテッド |
Treatment of RNase H1-related diseases by inhibition of natural antisense transcripts against RNase H1
|
JP5976548B2
(en)
|
2010-02-22 |
2016-08-23 |
カッパーアールエヌエー,インコーポレイテッド |
Treatment of pyrroline-5-carboxylate reductase 1 (PYCR1) related diseases by inhibition of natural antisense transcripts against PYCR1
|
CN102869777B
(en)
|
2010-04-02 |
2018-11-02 |
库尔纳公司 |
CSF3 relevant diseases are treated by inhibiting the natural antisense transcript of colony stimulating factor 3 (CSF3)
|
US9044494B2
(en)
|
2010-04-09 |
2015-06-02 |
Curna, Inc. |
Treatment of fibroblast growth factor 21 (FGF21) related diseases by inhibition of natural antisense transcript to FGF21
|
KR101915115B1
(en)
|
2010-05-03 |
2018-11-05 |
큐알엔에이, 인크. |
Treatment of sirtuin (sirt) related diseases by inhibition of natural antisense transcript to a sirtuin (sirt)
|
TWI586356B
(en)
|
2010-05-14 |
2017-06-11 |
可娜公司 |
Treatment of par4 related diseases by inhibition of natural antisense transcript to par4
|
CN102971423B
(en)
|
2010-05-26 |
2018-01-26 |
库尔纳公司 |
MSRA relevant diseases are treated by suppressing Methionine Sulfoxide Reductase A (MSRA) natural antisense transcript
|
NO2576783T3
(en)
|
2010-05-26 |
2018-04-28 |
|
|
PT2585596T
(en)
|
2010-06-23 |
2021-03-23 |
Curna Inc |
Treatment of sodium channel, voltage-gated, alpha subunit (scna) related diseases by inhibition of natural antisense transcript to scna
|
JP5998131B2
(en)
|
2010-07-14 |
2016-09-28 |
カッパーアールエヌエー,インコーポレイテッド |
DISCSLARGEHOMOLOG (DLG) Treatment of DLG-related diseases by inhibition of natural antisense transcripts on DLG1
|
CA2804847A1
(en)
|
2010-07-28 |
2012-02-02 |
Alcon Research Ltd. |
Sirna targeting vegfa and methods for treatment in vivo
|
ES2640755T3
(en)
|
2010-10-06 |
2017-11-06 |
Curna, Inc. |
Treatment of diseases related to Sialidase 4 (neu4) by inhibition of the natural antisense transcript to the neu4 gene
|
RU2597972C2
(en)
|
2010-10-22 |
2016-09-20 |
Курна Инк. |
Treatment of alpha-l-iduronidase (idua) related diseases by inhibition of natural antisense transcript to idua
|
WO2012068340A2
(en)
|
2010-11-18 |
2012-05-24 |
Opko Curna Llc |
Antagonat compositions and methods of use
|
WO2012071238A2
(en)
|
2010-11-23 |
2012-05-31 |
Opko Curna Llc |
Treatment of nanog related diseases by inhibition of natural antisense transcript to nanog
|
WO2012170771A1
(en)
|
2011-06-09 |
2012-12-13 |
Curna, Inc. |
Treatment of frataxin (fxn) related diseases by inhibition of natural antisense transcript to fxn
|
CN103874486A
(en)
|
2011-09-06 |
2014-06-18 |
库尔纳公司 |
Treatment of diseases related to alpha subunits of sodium channels, voltage-gated (scnxa) with small molecules
|
US20150031750A1
(en)
|
2012-03-15 |
2015-01-29 |
The Scripps Research Institute |
Treatment of brain derived neurotrophic factor (bdnf) related diseases by inhibition of natural antisense transcript to bdnf
|
US11002737B2
(en)
*
|
2016-09-29 |
2021-05-11 |
Worcester Polytechnic Institute |
Micro-array devices for capturing cells in blood and methods of their use
|