AU2001292564A1 - A method of transplantation using chemotherapy-treated allogeneic cells that enhance immune responses without graft versus host disease - Google Patents
A method of transplantation using chemotherapy-treated allogeneic cells that enhance immune responses without graft versus host diseaseInfo
- Publication number
- AU2001292564A1 AU2001292564A1 AU2001292564A AU9256401A AU2001292564A1 AU 2001292564 A1 AU2001292564 A1 AU 2001292564A1 AU 2001292564 A AU2001292564 A AU 2001292564A AU 9256401 A AU9256401 A AU 9256401A AU 2001292564 A1 AU2001292564 A1 AU 2001292564A1
- Authority
- AU
- Australia
- Prior art keywords
- transplantation
- chemotherapy
- immune responses
- host disease
- versus host
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 208000009329 Graft vs Host Disease Diseases 0.000 title 1
- 230000000735 allogeneic effect Effects 0.000 title 1
- 238000002512 chemotherapy Methods 0.000 title 1
- 208000024908 graft versus host disease Diseases 0.000 title 1
- 230000028993 immune response Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000002054 transplantation Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4621—Cellular immunotherapy characterized by the effect or the function of the cells immunosuppressive or immunotolerising
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/46434—Antigens related to induction of tolerance to non-self
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464499—Undefined tumor antigens, e.g. tumor lysate or antigens targeted by cells isolated from tumor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/464838—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0646—Natural killers cells [NK], NKT cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0648—Splenocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/26—Universal/off- the- shelf cellular immunotherapy; Allogenic cells or means to avoid rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/48—Blood cells, e.g. leukemia or lymphoma
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/06—Anti-neoplasic drugs, anti-retroviral drugs, e.g. azacytidine, cyclophosphamide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Developmental Biology & Embryology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22959300P | 2000-08-31 | 2000-08-31 | |
US60/229,593 | 2000-08-31 | ||
PCT/US2001/027214 WO2002017935A2 (en) | 2000-08-31 | 2001-08-31 | A method of transplantation using chemotherapy-treated allogeneic cells that enhance immune responses without graft versus host disease |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001292564A1 true AU2001292564A1 (en) | 2002-03-13 |
Family
ID=22861895
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001292564A Abandoned AU2001292564A1 (en) | 2000-08-31 | 2001-08-31 | A method of transplantation using chemotherapy-treated allogeneic cells that enhance immune responses without graft versus host disease |
Country Status (3)
Country | Link |
---|---|
US (1) | US20020127208A1 (en) |
AU (1) | AU2001292564A1 (en) |
WO (1) | WO2002017935A2 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7435592B2 (en) | 2003-05-13 | 2008-10-14 | Immunovative Therapies, Ltd. | Compositions for allogeneic cell therapy |
US7402431B2 (en) * | 2004-03-01 | 2008-07-22 | Immunovative Therapies, Ltd. | T-cell therapy formulation |
PT2573166T (en) | 2004-02-26 | 2016-07-07 | Immunovative Therapies Ltd | Methods for preparing t-cells for cell therapy |
US7592431B2 (en) | 2004-02-26 | 2009-09-22 | Immunovative Therapies, Ltd. | Biodegradable T-cell Activation device |
WO2006007515A2 (en) * | 2004-07-01 | 2006-01-19 | Board Of Regents, The University Of Texas System | Functional assessment, specific enrichment and specific depletion of alloreactive human t cells |
CA2736851A1 (en) * | 2008-09-11 | 2010-03-18 | Lung-Ji Chang | System and method for producing t cells |
AU2012250807A1 (en) | 2011-05-03 | 2013-12-12 | Immunovative Therapies, Ltd. | Induction of IL-12 using immunotherapy |
CA2838041C (en) | 2011-05-03 | 2018-09-25 | Immunovative Therapies, Ltd. | Methods for handling biological drugs containing living cells |
CN110913873A (en) * | 2017-02-23 | 2020-03-24 | 希望之城 | For CD8+Method for in vivo expansion of T cells and prevention or treatment of GVHD |
WO2018170335A1 (en) | 2017-03-15 | 2018-09-20 | Orca Biosystems Inc. | Compositions and methods for hematopoietic stem cell transplants |
CN114732807A (en) * | 2022-03-27 | 2022-07-12 | 苏州大学 | Application of mitoxantrone in preparation of medicine for preventing or treating acute graft-versus-host disease |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5800539A (en) * | 1995-11-08 | 1998-09-01 | Emory University | Method of allogeneic hematopoietic stem cell transplantation without graft failure or graft vs. host disease |
-
2001
- 2001-08-31 US US09/945,339 patent/US20020127208A1/en not_active Abandoned
- 2001-08-31 AU AU2001292564A patent/AU2001292564A1/en not_active Abandoned
- 2001-08-31 WO PCT/US2001/027214 patent/WO2002017935A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2002017935A3 (en) | 2002-10-24 |
WO2002017935A2 (en) | 2002-03-07 |
US20020127208A1 (en) | 2002-09-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2002232447A1 (en) | Method of enhancing lymphocyte-mediated immune responses | |
AU2002212006A1 (en) | Artificial disc | |
AU2001294520A1 (en) | Methods and compositions for increasing protein yield from a cell culture | |
IL219266A0 (en) | Compositions and methods for priming monocytic dendritic cells and t cells for th-1 response | |
AU2001229731A1 (en) | Human embryoid body-derived cells | |
AU4708601A (en) | Method for enhancing immune responses in mammals | |
AU2001292564A1 (en) | A method of transplantation using chemotherapy-treated allogeneic cells that enhance immune responses without graft versus host disease | |
AU6373501A (en) | Preparation that contains the intestinal beneficial bacterium fermentation culture | |
AU2002242085A1 (en) | Methods and compositions useful for stimulating an immune response | |
AU1078801A (en) | Data extractor | |
AU2001278734A1 (en) | Method of extensive culture of antigen-specific cytotoxic t cells | |
EP1534330B8 (en) | Whole bacterial cells as immune modulator | |
AU2002222176A1 (en) | Time synchronisation | |
AU2003287584A1 (en) | Conjugated fatty acid based emulsion and methods for preparing and using same | |
AU2003221579A1 (en) | Encapsulated cells to elicit immune response | |
AU2003261353A1 (en) | High density reagent array preparation methods | |
AU2003302234A1 (en) | Immune response associated proteins | |
AU2001268414A1 (en) | Method for assessing cortical response to blue light | |
AU2001253481A1 (en) | Methods and compositions for eleciting an immune response | |
AU2001245552A1 (en) | Transcutaneous immunization for large particulate antigens | |
AU2002366026A1 (en) | Frying method | |
AU2002340786A1 (en) | Fat splitting process | |
GB2351905B (en) | Eliciting improved immune responses | |
AU2001245815A1 (en) | Human immune response proteins | |
AU2003268230A1 (en) | Immune response associated proteins |