AU2001291960A1 - Polysaccharides with antithrombotic activity comprising at least a covalent bond with biotin or a biotin derivative - Google Patents

Polysaccharides with antithrombotic activity comprising at least a covalent bond with biotin or a biotin derivative

Info

Publication number: AU2001291960A1
Authority: AU; Australia
Prior art keywords: biotin; polysaccharides; covalent bond; antithrombotic activity; derivative
Prior art date: 2000-09-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

AU2001291960A

Other versions

AU2001291960C1 (en

AU2001291960B2 (en

Inventor

Philippe Duchaussoy

Jean-Marc Herbert

Maurice Petitou

Pierre Savi

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sanofi Aventis France

Original Assignee

Sanofi Aventis France

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-09-22

Filing date

2001-09-20

Publication date

2002-06-20

2000-09-22 Priority claimed from FR0012094A external-priority patent/FR2814463B1/en

2001-09-20 Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France

2002-06-20 Publication of AU2001291960A1 publication Critical patent/AU2001291960A1/en

2004-04-08 Assigned to SANOFI-SYNTHELABO reassignment SANOFI-SYNTHELABO Request for Assignment Assignors: AKZO NOBEL NV, SANOFI-SYNTHELABO

2005-02-17 Assigned to SANOFI-AVENTIS reassignment SANOFI-AVENTIS Amend patent request/document other than specification (104) Assignors: SANOFI-SYNTHELABO

2007-03-01 Application granted granted Critical

2007-03-01 Publication of AU2001291960B2 publication Critical patent/AU2001291960B2/en

2009-10-08 Publication of AU2001291960C1 publication Critical patent/AU2001291960C1/en

2021-09-20 Anticipated expiration legal-status Critical

Status Ceased legal-status Critical Current

Links

230000002785 anti-thrombosis Effects 0.000 title 1
YBJHBAHKTGYVGT-ZKWXMUAHSA-N biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 title 1
229960002685 biotin Drugs 0.000 title 1
235000020958 biotin Nutrition 0.000 title 1
239000011616 biotin Substances 0.000 title 1
150000001615 biotins Chemical class 0.000 title 1
150000004676 glycans Polymers 0.000 title 1
229920001282 polysaccharide Polymers 0.000 title 1
239000005017 polysaccharide Substances 0.000 title 1
150000004804 polysaccharides Polymers 0.000 title 1

AU2001291960A 2000-09-22 2001-09-20 Polysaccharides with antithrombotic activity comprising at least a covalent bond with biotin or a biotin derivative Ceased AU2001291960C1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR00/12094		2000-09-22
FR0012094A FR2814463B1 (en)	2000-09-22	2000-09-22	NOVEL POLYSACCHARIDES WITH ANTITHROMBOTIC ACTIVITY COMPRISING AT LEAST ONE COVALENT BINDING WITH BIOTIN OR A BIOTINE DERIVATIVE
PCT/FR2001/002918 WO2002024754A1 (en)	2000-09-22	2001-09-20	Polysaccharides with antithrombotic activity comprising at least a covalent bond with biotin or a biotin derivative

Publications (3)

Publication Number	Publication Date
AU2001291960A1 true AU2001291960A1 (en)	2002-06-20
AU2001291960B2 AU2001291960B2 (en)	2007-03-01
AU2001291960C1 AU2001291960C1 (en)	2009-10-08

Family

ID=8854579

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AU2001291960A Ceased AU2001291960C1 (en)	2000-09-22	2001-09-20	Polysaccharides with antithrombotic activity comprising at least a covalent bond with biotin or a biotin derivative
AU9196001A Pending AU9196001A (en)	2000-09-22	2001-09-20	Polysaccharides with antithrombotic activity comprising at least a covalent bondwith biotin or a biotin derivative

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AU9196001A Pending AU9196001A (en)	2000-09-22	2001-09-20	Polysaccharides with antithrombotic activity comprising at least a covalent bondwith biotin or a biotin derivative

Country Status (40)

Country	Link
US (3)	US6844329B2 (en)
EP (1)	EP1322673B1 (en)
JP (2)	JP5016778B2 (en)
KR (2)	KR100891388B1 (en)
CN (1)	CN1235914C (en)
AR (1)	AR030774A1 (en)
AT (1)	ATE374215T1 (en)
AU (2)	AU2001291960C1 (en)
BG (1)	BG66191B1 (en)
BR (1)	BR0114007A (en)
CA (1)	CA2418815C (en)
CY (1)	CY1108076T1 (en)
CZ (1)	CZ300856B6 (en)
DE (1)	DE60130669T2 (en)
DK (1)	DK1322673T3 (en)
EA (1)	EA005133B1 (en)
EC (1)	ECSP034514A (en)
EE (1)	EE05202B1 (en)
ES (1)	ES2292625T3 (en)
FR (1)	FR2814463B1 (en)
GE (1)	GEP20053616B (en)
HK (1)	HK1053316A1 (en)
HR (1)	HRP20030219B1 (en)
HU (2)	HU1400034D0 (en)
IL (2)	IL154848A0 (en)
IS (1)	IS2550B (en)
ME (2)	ME00080B (en)
MX (1)	MXPA03002483A (en)
NO (2)	NO332905B1 (en)
NZ (1)	NZ524472A (en)
PE (1)	PE20020471A1 (en)
PL (1)	PL206727B1 (en)
PT (1)	PT1322673E (en)
RS (1)	RS50730B (en)
SI (1)	SI1322673T1 (en)
SK (2)	SK287054B6 (en)
TW (1)	TWI308153B (en)
UA (1)	UA79736C2 (en)
WO (1)	WO2002024754A1 (en)
ZA (1)	ZA200301692B (en)

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FR2814463B1 (en) *	2000-09-22	2002-11-15	Sanofi Synthelabo	NOVEL POLYSACCHARIDES WITH ANTITHROMBOTIC ACTIVITY COMPRISING AT LEAST ONE COVALENT BINDING WITH BIOTIN OR A BIOTINE DERIVATIVE
FR2874924B1 (en)	2004-09-09	2006-12-01	Sanofi Aventis Sa	BIOTINYLATED HEXADECASACCHARIDES, THEIR PREPARATION AND THEIR THERAPEUTIC USE
TWI403334B (en) *	2004-12-23	2013-08-01	Merck Sharp & Dohme	Antithrombotic dual inhibitors comprising a biotin residue
TWI376234B (en) *	2005-02-01	2012-11-11	Msd Oss Bv	Conjugates of a polypeptide and an oligosaccharide
KR20080055960A (en) *	2005-10-10	2008-06-19	엔.브이.오가논	Anticoagulant antithrombotic dual inhibitors comprising a biotin label
ES2362011T3 (en) *	2005-10-10	2011-06-27	N.V. Organon	ANTICOAGULANT ANTICHROGULATING DUAL INHIBITORS THAT INCLUDE A BIOTINE BRAND.
CN1317035C (en) *	2005-10-24	2007-05-23	天津大学	Method for assembling multi-biological functional factor on micro-particle surface based on hydrazide group
EP1886696A1 (en) *	2006-08-03	2008-02-13	Endotis Pharma	Conjugates of antithrombin binding oligosaccharide derivatives and therapeutic proteins
FR2912409B1 (en) *	2007-02-14	2012-08-24	Sanofi Aventis	LOW MOLECULAR WEIGHT HEPARINS COMPRISING AT LEAST ONE BINDING WITH BIOTIN OR A BIOTIN DERIVATIVE OF THEIR PREPARATION METHOD, THEIR USE
EP2145624A1 (en)	2008-07-18	2010-01-20	Sanofi-Aventis	Use of idrabiotaparinux for decreasing the incidence of bleedings during an antithrombotic treatment
TW201006479A (en) *	2008-07-18	2010-02-16	Sanofi Aventis	Use of idrabiotaparinux for decreasing the incidence of bleedings during an antithrombotic treatment
EP2233143A1 (en)	2009-03-24	2010-09-29	Sanofi-Aventis	Use of idrabiotaparinux for decreasing the incidence of bleedings during an antithrombotic treatment
FR2935386B1 (en) *	2008-08-26	2010-09-10	Sanofi Aventis	NOVEL POLYSACCHARIDES WITH ANTITHROMBOTIC ACTIVITY COMPRISING A COVALENT LIAISON WITH AN AMINO CHAIN
EP2323605A4 (en) *	2008-09-10	2014-02-05	Syneron Medical Ltd	Transdermal delivery of oligosaccharides
CA3014688A1 (en)	2008-12-19	2010-07-15	Supernus Pharmaceuticals, Inc.	Use of molindone for the treatment of aggression, irritability, or impulsivity
FR2952935B1 (en) *	2009-11-20	2011-12-02	Sanofi Aventis	PROCESS FOR THE PREPARATION OF SUCCINIMIDYL N-BIOTINYL-6-AMINOCAPROATE
CN102892411B (en)	2009-12-18	2015-01-21	恩多提斯药业公司	Pharmaceutical oral dosage form containing a synthetic oligosaccharide
CZ302510B6 (en) *	2010-03-29	2011-06-22	Univerzita Palackého v Olomouci	Efficient method of biotinylation of compounds containing carboxyl group using solid phase synthesis for affinity chromatography needs
CZ302669B6 (en) *	2010-03-29	2011-08-24	Univerzita Palackého v Olomouci	Efficient method of biotinylation of amino compounds using solid phase synthesis for affinity chromatography needs
WO2011123497A1 (en)	2010-03-31	2011-10-06	Supernus Pharmaceuticals Inc.	Stabilized formulations of cns compounds
FR2964660B1 (en) *	2010-09-10	2012-09-28	Sanofi Aventis	NOVEL BIOTINYL POLYSACCHARIDES WITH ANTITHROMBOTIC ACTIVITY AND IMPROVED METABOLIC STABILITY
EP2614089A1 (en) *	2010-09-10	2013-07-17	Sanofi-Aventis	Biotinylated polysaccharides having an antithrombotic activity and improved metabolic stability
EP2484366A1 (en)	2011-02-07	2012-08-08	Sanofi	Idrabiotaparinux for the treatment of pulmonary embolism and for the secondary prevention of venous thromboembolic events
WO2012172104A1 (en)	2011-06-17	2012-12-20	Endotis Pharma	Synthetic pentasaccharides having short half-life and high activity
AU2013344920A1 (en) *	2012-11-13	2015-04-30	Supernus Pharmaceuticals, Inc.	Method of treatment of aggression
WO2015195404A1 (en)	2014-06-20	2015-12-23	The United States Of America, As Represented By The Secretary, Department Of Health & Human Services	Methods for detection of an analyte by movement of tethered microparticles
WO2016205239A1 (en)	2015-06-15	2016-12-22	The United States Of America, As Represented By The Secretary Department Of Health And Human Services	Non-hormonal mammalian sperm decoy contraception based on the n-terminus of the zp2 protein
WO2018076025A1 (en)	2016-10-21	2018-04-26	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Molecular nanotags
CN108976318B (en) *	2017-06-01	2021-03-30	首都医科大学	Mono-6- (biotinimido) -6-deoxy-beta-cyclodextrin and preparation method and application thereof
WO2019133727A1 (en)	2017-12-29	2019-07-04	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Universal influenza virus probe set for enrichment of any influenza virus nucleic acid
CA3144968A1 (en)	2019-07-09	2021-01-14	Optimvia Llc	Methods for synthesizing anticoagulant polysaccharides
CN114556685B (en) *	2019-10-17	2024-04-02	株式会社自动网络技术研究所	Wiring module
WO2022056078A1 (en)	2020-09-11	2022-03-17	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Rnase h-assisted detection assay for rna (radar)

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Publication number	Priority date	Publication date	Assignee	Title
US3960884A (en) *	1974-04-24	1976-06-01	Sergei Ivanovich Zavyalov	Method of preparing racemic biotin
AU563351C (en) *	1982-01-15	2003-06-19	Glaxo Group Limited	Synthesis of oligosaccharides
IL102758A (en) *	1991-08-23	1997-03-18	Akzo Nv	Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them
WO2000002050A1 (en) *	1998-07-07	2000-01-13	Department Of Radiation Oncology, University Of Washington	Trifunctional reagent for conjugation to a biomolecule
US20010023288A1 (en) *	1999-07-07	2001-09-20	Wilbur D. Scott	Trifunctional reagent for conjugation to a biomolecule
FR2751334B1 (en) *	1996-07-19	1998-10-16	Sanofi Sa	SYNTHETIC POLYSACCHARIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2773804B1 (en) *	1998-01-19	2000-02-18	Sanofi Sa	SYNTHESIS POLYSACCHARIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
FR2773801B1 (en) *	1998-01-19	2000-05-12	Sanofi Sa	NOVEL PENTASACCHARIDES, METHODS FOR THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
GB2335490B (en) *	1998-03-20	2003-05-14	Ortho Clinical Diagnostics	An assay surface that permits an analyte releasiing step
US6492503B1 (en)	1998-07-31	2002-12-10	Seikagaku Corporation	Glycosaminoglycan and drug compositions containing the same
FR2814463B1 (en) *	2000-09-22	2002-11-15	Sanofi Synthelabo	NOVEL POLYSACCHARIDES WITH ANTITHROMBOTIC ACTIVITY COMPRISING AT LEAST ONE COVALENT BINDING WITH BIOTIN OR A BIOTINE DERIVATIVE

2000
- 2000-09-22 FR FR0012094A patent/FR2814463B1/en not_active Expired - Fee Related
2001
- 2001-09-20 SK SK356-2003A patent/SK287054B6/en not_active IP Right Cessation
- 2001-09-20 SI SI200130786T patent/SI1322673T1/en unknown
- 2001-09-20 KR KR1020037004108A patent/KR100891388B1/en not_active IP Right Cessation
- 2001-09-20 CN CNB018161588A patent/CN1235914C/en not_active Expired - Fee Related
- 2001-09-20 JP JP2002529162A patent/JP5016778B2/en not_active Expired - Fee Related
- 2001-09-20 US US10/381,154 patent/US6844329B2/en not_active Expired - Lifetime
- 2001-09-20 PL PL363368A patent/PL206727B1/en unknown
- 2001-09-20 ES ES01972171T patent/ES2292625T3/en not_active Expired - Lifetime
- 2001-09-20 IL IL15484801A patent/IL154848A0/en unknown
- 2001-09-20 ME MEP-2008-236A patent/ME00080B/en unknown
- 2001-09-20 NZ NZ524472A patent/NZ524472A/en not_active IP Right Cessation
- 2001-09-20 DK DK01972171T patent/DK1322673T3/en active
- 2001-09-20 AT AT01972171T patent/ATE374215T1/en active
- 2001-09-20 BR BR0114007-8A patent/BR0114007A/en active Search and Examination
- 2001-09-20 UA UA2003021719A patent/UA79736C2/en unknown
- 2001-09-20 MX MXPA03002483A patent/MXPA03002483A/en active IP Right Grant
- 2001-09-20 ME MEP-236/08A patent/MEP23608A/en unknown
- 2001-09-20 PT PT01972171T patent/PT1322673E/en unknown
- 2001-09-20 RS YUP-197/03A patent/RS50730B/en unknown
- 2001-09-20 WO PCT/FR2001/002918 patent/WO2002024754A1/en active Application Filing
- 2001-09-20 AU AU2001291960A patent/AU2001291960C1/en not_active Ceased
- 2001-09-20 AU AU9196001A patent/AU9196001A/en active Pending
- 2001-09-20 KR KR1020087009747A patent/KR20080049139A/en not_active Application Discontinuation
- 2001-09-20 CA CA2418815A patent/CA2418815C/en not_active Expired - Fee Related
- 2001-09-20 SK SK5031-2009A patent/SK287218B6/en not_active IP Right Cessation
- 2001-09-20 HU HUP1400034 patent/HU1400034D0/en not_active Application Discontinuation
- 2001-09-20 EA EA200300237A patent/EA005133B1/en not_active IP Right Cessation
- 2001-09-20 HU HU0303551A patent/HUP0303551A3/en not_active Application Discontinuation
- 2001-09-20 GE GE5103A patent/GEP20053616B/en unknown
- 2001-09-20 CZ CZ20030814A patent/CZ300856B6/en not_active IP Right Cessation
- 2001-09-20 DE DE60130669T patent/DE60130669T2/en not_active Expired - Lifetime
- 2001-09-20 EP EP01972171A patent/EP1322673B1/en not_active Expired - Lifetime
- 2001-09-20 EE EEP200300114A patent/EE05202B1/en not_active IP Right Cessation
- 2001-09-20 AR ARP010104436A patent/AR030774A1/en not_active Application Discontinuation
- 2001-09-21 PE PE2001000952A patent/PE20020471A1/en not_active Application Discontinuation
- 2001-09-21 TW TW090123340A patent/TWI308153B/en not_active IP Right Cessation
2003
- 2003-02-28 IS IS6733A patent/IS2550B/en unknown
- 2003-02-28 ZA ZA200301692A patent/ZA200301692B/en unknown
- 2003-03-10 IL IL154848A patent/IL154848A/en not_active IP Right Cessation
- 2003-03-14 EC EC2003004514A patent/ECSP034514A/en unknown
- 2003-03-20 NO NO20031295A patent/NO332905B1/en not_active IP Right Cessation
- 2003-03-20 BG BG107650A patent/BG66191B1/en unknown
- 2003-03-21 HR HR20030219A patent/HRP20030219B1/en not_active IP Right Cessation
- 2003-08-05 HK HK03105615A patent/HK1053316A1/en not_active IP Right Cessation
2005
- 2005-01-14 US US11/035,717 patent/US7943595B2/en not_active Expired - Fee Related
2007
- 2007-12-04 CY CY20071101542T patent/CY1108076T1/en unknown
2011
- 2011-02-28 US US13/036,143 patent/US8318696B2/en not_active Expired - Fee Related
- 2011-03-16 NO NO20110401A patent/NO20110401L/en not_active Application Discontinuation
2012
- 2012-02-10 JP JP2012027377A patent/JP2012131809A/en active Pending

Publication	Publication Date	Title
AU2001291960A1 (en)	2002-06-20	Polysaccharides with antithrombotic activity comprising at least a covalent bond with biotin or a biotin derivative
IL154848A0 (en)	2003-10-31	Polysaccharides with antithrombotic activity comprising at least a covalent bond with biotin or a biotin derivative
AU5018100A (en)	2000-12-05	Bracket assembly including a reservoir
AUPQ376399A0 (en)	1999-11-25	A structural member
EP1191039A4 (en)	2002-08-14	Polysaccharide derivative
AUPP798998A0 (en)	1999-01-28	A parenteral catheter assembly
AU6402600A (en)	2000-12-28	Improved-guidewire-access modular intraluminal prosthesis with connecting section
AUPP826999A0 (en)	1999-02-11	A mounting arrangement
AUPP923099A0 (en)	1999-04-15	A ball
AU7568800A (en)	2001-03-19	A firearm
IL149628A0 (en)	2002-11-10	Antithrombotic compound
AU6377800A (en)	2001-02-13	Compositions comprising xet and a polysaccharide and/or oligosaccharide
AU8018200A (en)	2001-05-14	A knowledge-engineering protocol-suite
AUPQ254299A0 (en)	1999-09-23	A garment
PL344721A1 (en)	2001-07-02	Facing element incorporating a decorative portion
AU7547500A (en)	2001-05-10	A decorative article
AU5752000A (en)	2001-01-09	In-sink micro-machine
GB2357816B (en)	2003-12-24	A vehicle differential assembly
AUPQ142499A0 (en)	1999-07-29	A surrogate
AUPP858999A0 (en)	1999-03-04	A body compress
AUPQ265399A0 (en)	1999-09-30	A versatile toy
AUPQ364299A0 (en)	1999-11-18	A bracket arrangement
AUPP992999A0 (en)	1999-05-20	A bracket
AUPP842299A0 (en)	1999-02-25	A pipe connection assembly
AUPQ383999A0 (en)	1999-11-25	A toy vehicle assembly