AU2001291854A1 - Antibacterials mutilins - Google Patents

Antibacterials mutilins

Info

Publication number
AU2001291854A1
AU2001291854A1 AU2001291854A AU9185401A AU2001291854A1 AU 2001291854 A1 AU2001291854 A1 AU 2001291854A1 AU 2001291854 A AU2001291854 A AU 2001291854A AU 9185401 A AU9185401 A AU 9185401A AU 2001291854 A1 AU2001291854 A1 AU 2001291854A1
Authority
AU
Australia
Prior art keywords
mutilins
antibacterials
antibacterials mutilins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001291854A
Inventor
Gerd Ascher
Heinz Berner
Johannes Hildebrandt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz GmbH
Original Assignee
Biochemie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0022439A external-priority patent/GB0022439D0/en
Priority claimed from GB0022440A external-priority patent/GB0022440D0/en
Priority claimed from GB0024674A external-priority patent/GB0024674D0/en
Application filed by Biochemie GmbH filed Critical Biochemie GmbH
Publication of AU2001291854A1 publication Critical patent/AU2001291854A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/54—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2001291854A 2000-09-13 2001-09-11 Antibacterials mutilins Abandoned AU2001291854A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB0022439A GB0022439D0 (en) 2000-09-13 2000-09-13 Organic compounds
GB0022440 2000-09-13
GB0022440A GB0022440D0 (en) 2000-09-13 2000-09-13 Organic Compounds
GB0022439 2000-09-13
GB0024674A GB0024674D0 (en) 2000-10-09 2000-10-09 Organic compounds
GB0024674 2000-10-09
PCT/EP2001/010502 WO2002022580A1 (en) 2000-09-13 2001-09-11 Antibacterials mutilins

Publications (1)

Publication Number Publication Date
AU2001291854A1 true AU2001291854A1 (en) 2002-03-26

Family

ID=27255885

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001291854A Abandoned AU2001291854A1 (en) 2000-09-13 2001-09-11 Antibacterials mutilins

Country Status (17)

Country Link
US (3) US7169804B2 (en)
EP (1) EP1320525B1 (en)
JP (1) JP5134181B2 (en)
CN (1) CN1288134C (en)
AR (1) AR030651A1 (en)
AT (1) ATE264843T1 (en)
AU (1) AU2001291854A1 (en)
BR (1) BRPI0113837B8 (en)
CA (1) CA2418538C (en)
DE (1) DE60102936T2 (en)
ES (1) ES2220809T3 (en)
HK (1) HK1079506A1 (en)
MY (1) MY133930A (en)
PE (1) PE20020676A1 (en)
PT (1) PT1320525E (en)
TW (1) TWI306852B (en)
WO (1) WO2002022580A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9918037D0 (en) * 1999-07-30 1999-09-29 Biochemie Gmbh Organic compounds
GB0207495D0 (en) 2002-03-28 2002-05-08 Biochemie Gmbh Organic compounds
GB0209262D0 (en) * 2002-04-23 2002-06-05 Biochemie Gmbh Organic compounds
EP1534678B1 (en) * 2002-07-24 2007-10-31 Nabriva Therapeutics Forschungs GmbH Pleuromutilin derivatives as antimicrobbials
GB0308114D0 (en) * 2003-04-08 2003-05-14 Glaxo Group Ltd Novel compounds
US7544963B2 (en) * 2005-04-29 2009-06-09 Cree, Inc. Binary group III-nitride based high electron mobility transistors
GB0513058D0 (en) * 2005-06-27 2005-08-03 Sandoz Ag Organic compounds
WO2007037518A1 (en) * 2005-09-29 2007-04-05 Dainippon Sumitomo Pharma Co., Ltd. Mutilin derivative and pharmaceutical composition containing the same
EP1808431A1 (en) * 2006-01-16 2007-07-18 Nabriva Therapeutics Forschungs GmbH Mutilin derivatives and their use as pharmaceutical
CA2654450A1 (en) * 2006-06-05 2007-12-13 Auspex Pharmaceuticals, Inc. Preparation and utility of substituted erythromycin analogs
EP1908750A1 (en) * 2006-10-05 2008-04-09 Nabriva Therapeutics Forschungs GmbH Process for the preparation of pleuromutilins
WO2008143343A1 (en) 2007-05-24 2008-11-27 Kyorin Pharmaceutical Co., Ltd. Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position
US20100184987A1 (en) * 2008-11-13 2010-07-22 Teva Pharmaceutical Industries Ltd. Preparation of Retapamulin via its Pleuromutilin-thiol precursor
CN103709115A (en) * 2012-10-09 2014-04-09 山东亨利医药科技有限责任公司 Pleuromutilin antibiotic derivatives
TWI762573B (en) 2017-02-10 2022-05-01 奧地利商納畢瓦治療有限責任公司 Purification of pleuromutilin

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE789629A (en) * 1971-10-05 1973-04-03 Sandoz Sa NEW DERIVATIVES OF PLEUROMUTILINE, THEIR PREPARATION AND THERAPEUTIC APPLICATION
DE2811314A1 (en) * 1978-03-16 1979-09-27 Sandoz Ag Coccidiostatic combination preparations - contg. a polyether antibiotic e.g. salinomycin and a mutilin cpd. e.g. tiamulin
DE2966635D1 (en) 1979-01-12 1984-03-08 Sandoz Ag New pleuromutilin derivatives, their production and pharmaceutical compositions containing them
ZA80175B (en) * 1979-01-12 1981-08-26 Sandoz Ltd New pleuromutilin derivatives, their production and use
EP0153277B1 (en) * 1984-02-17 1987-08-26 Sandoz Ag Pleuromutilin derivatives, process for their preparation and their use
JP3054875B2 (en) * 1995-02-13 2000-06-19 株式会社小松製作所 Plasma torch
IL124912A0 (en) * 1996-01-03 1999-01-26 Smithkline Beecham Plc Carbamoyloxy derivatives of mutiline and their use as antibacterials
UY25225A1 (en) 1997-10-29 2000-12-29 Smithkline Beecham Plc PLEUROMUTILINE DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS
WO2000027790A1 (en) 1998-11-11 2000-05-18 Smithkline Beecham P.L.C. Mutilin compounds
AU3036200A (en) 1998-12-18 2000-07-12 Smithkline Beecham Plc Mutilin 14-ester derivatives having antibacterial activity
GB9918037D0 (en) * 1999-07-30 1999-09-29 Biochemie Gmbh Organic compounds
GB0207495D0 (en) * 2002-03-28 2002-05-08 Biochemie Gmbh Organic compounds
EP1534678B1 (en) * 2002-07-24 2007-10-31 Nabriva Therapeutics Forschungs GmbH Pleuromutilin derivatives as antimicrobbials

Also Published As

Publication number Publication date
WO2002022580A1 (en) 2002-03-21
CN1288134C (en) 2006-12-06
TWI306852B (en) 2009-03-01
PE20020676A1 (en) 2002-08-27
MY133930A (en) 2007-11-30
EP1320525A1 (en) 2003-06-25
HK1079506A1 (en) 2006-04-07
EP1320525B1 (en) 2004-04-21
ES2220809T3 (en) 2004-12-16
CN1633415A (en) 2005-06-29
US20070135483A1 (en) 2007-06-14
US7169804B2 (en) 2007-01-30
US20040102482A1 (en) 2004-05-27
US7569587B2 (en) 2009-08-04
CA2418538A1 (en) 2002-03-21
BR0113837A (en) 2003-06-03
JP5134181B2 (en) 2013-01-30
BRPI0113837B8 (en) 2021-05-25
AR030651A1 (en) 2003-08-27
JP2004509107A (en) 2004-03-25
BRPI0113837B1 (en) 2019-01-29
ATE264843T1 (en) 2004-05-15
PT1320525E (en) 2004-09-30
DE60102936D1 (en) 2004-05-27
CA2418538C (en) 2009-12-22
US20090209584A1 (en) 2009-08-20
DE60102936T2 (en) 2005-03-24

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