AU2001283355A1 - Compositions containing hypotriglyceridemically active stilbenoids - Google Patents

Compositions containing hypotriglyceridemically active stilbenoids

Info

Publication number
AU2001283355A1
AU2001283355A1 AU2001283355A AU8335501A AU2001283355A1 AU 2001283355 A1 AU2001283355 A1 AU 2001283355A1 AU 2001283355 A AU2001283355 A AU 2001283355A AU 8335501 A AU8335501 A AU 8335501A AU 2001283355 A1 AU2001283355 A1 AU 2001283355A1
Authority
AU
Australia
Prior art keywords
compositions containing
hypotriglyceridemically active
stilbenoids
active stilbenoids
hypotriglyceridemically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001283355A
Inventor
David Craig Hoppe
Wayne D. Inman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Insmed Inc
Original Assignee
Insmed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Insmed Inc filed Critical Insmed Inc
Publication of AU2001283355A1 publication Critical patent/AU2001283355A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Optical Head (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Seasonings (AREA)

Abstract

The use of isolated or purified stilbenoid compounds including longistyline A-2-carboxylic acid as a dietary supplement to mammals suffering from elevated triglyceride levels is described. The invention also relates to the use of such stibenoid compounds in combination with other hypotriglyceridemic agents.
AU2001283355A 2000-08-16 2001-08-15 Compositions containing hypotriglyceridemically active stilbenoids Abandoned AU2001283355A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22570400P 2000-08-16 2000-08-16
US60/225,704 2000-08-16
US09/920,304 US6541522B2 (en) 2000-08-16 2001-08-02 Methods of using compositions containing hypotriglyceridemically active stilbenoids
US09/920,304 2001-08-02
PCT/US2001/025383 WO2002013806A2 (en) 2000-08-16 2001-08-15 Compositions containing hypotriglyceridemically active stilbenoids

Publications (1)

Publication Number Publication Date
AU2001283355A1 true AU2001283355A1 (en) 2002-02-25

Family

ID=26919840

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001283355A Abandoned AU2001283355A1 (en) 2000-08-16 2001-08-15 Compositions containing hypotriglyceridemically active stilbenoids

Country Status (6)

Country Link
US (1) US6541522B2 (en)
EP (1) EP1311258B1 (en)
AT (1) ATE292460T1 (en)
AU (1) AU2001283355A1 (en)
DE (1) DE60109938T2 (en)
WO (1) WO2002013806A2 (en)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020058708A1 (en) * 2000-08-16 2002-05-16 Inman Wayne D. Compositions containing hypotriglyceridemically active stilbenoids
US6410596B1 (en) * 2000-08-16 2002-06-25 Insmed Incorporated Compositions containing hypoglycemically active stillbenoids
US6552085B2 (en) 2000-08-16 2003-04-22 Insmed Incorporated Compositions containing hypoglycemically active stilbenoids
US7977049B2 (en) * 2002-08-09 2011-07-12 President And Fellows Of Harvard College Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms
US20050080024A1 (en) * 2002-08-15 2005-04-14 Joseph Tucker Nitric oxide donating derivatives for the treatment of cardiovascular disorders
US20050080021A1 (en) * 2002-08-15 2005-04-14 Joseph Tucker Nitric oxide donating derivatives of stilbenes, polyphenols and flavonoids for the treatment of cardiovascular disorders
JP2007530417A (en) * 2003-07-01 2007-11-01 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ Composition for manipulating the longevity and stress response of cells and organisms
US20060025337A1 (en) * 2003-07-01 2006-02-02 President And Fellows Of Harvard College Sirtuin related therapeutics and diagnostics for neurodegenerative diseases
JP2007527418A (en) 2003-12-29 2007-09-27 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ Composition for treating or preventing obesity and insulin resistance disorders
US8017634B2 (en) 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
AR047658A1 (en) 2004-02-03 2006-02-01 Cargill Inc CONCENTRATE OF PROTEINS AND WATER CURRENT WITH HYDROSOLUBBLE CARBOHYDRATES
US20060084085A1 (en) * 2004-06-16 2006-04-20 Sinclair David A Methods and compositions for modulating Bax-mediated apoptosis
WO2006004722A2 (en) * 2004-06-30 2006-01-12 Biomol Research Laboratories, Inc. Compositions and methods for selectively activating human sirtuins
EP1838296B1 (en) * 2004-10-20 2012-08-08 Resverlogix Corp. Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases
WO2006138418A2 (en) * 2005-06-14 2006-12-28 President And Fellows Of Harvard College Improvement of cognitive performance with sirtuin activators
US20070149466A1 (en) * 2005-07-07 2007-06-28 Michael Milburn Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders
EP2314295B1 (en) * 2005-07-29 2015-01-28 Resverlogix, Inc Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
US20070029101A1 (en) * 2005-08-05 2007-02-08 Paul Croas Hammerhead forcible entry tool used to defeat burglar bars
WO2008075528A1 (en) * 2006-12-20 2008-06-26 Kurohime Medical Co., Ltd. Use of h. macrophylla tea
US8053440B2 (en) * 2007-02-01 2011-11-08 Resverlogix Corporation Compounds for the prevention and treatment of cardiovascular diseases
US7824714B2 (en) * 2008-06-13 2010-11-02 Development Center For Biotechnology Chinese herb extract for treating dementia and preparation method thereof
PT2346837E (en) 2008-06-26 2015-04-02 Resverlogix Corp Methods of preparing quinazolinone derivatives
ES2542835T3 (en) 2009-01-08 2015-08-12 Resverlogix Corporation Compounds for the prevention and treatment of cardiovascular diseases
BRPI1009315B8 (en) 2009-03-18 2021-05-25 Resverlogix Corp anti-inflammatory compounds and their pharmaceutical compositions
TR201818390T4 (en) 2009-04-22 2019-01-21 Resverlogix Corp NEW ANTI-INFLAMMATORY AGENTS
US8815310B2 (en) * 2011-01-10 2014-08-26 Morteza Naghavi Compositions for boosting metabolism, assisting weight loss, and promoting cardiovascular health
PL2773354T3 (en) 2011-11-01 2019-12-31 Resverlogix Corp. Oral immediate release formulations for substituted quinazolinones
CN105030750B (en) * 2011-12-23 2018-08-28 中国医学科学院医药生物技术研究所 Application of one group of cajanin structurally similar compounds in anti-hepatitis C virus and anti AIDS virus
WO2014080291A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Biaryl derivatives as bromodomain inhibitors
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
CA2895905A1 (en) 2012-12-21 2014-06-26 Zenith Epigenetics Corp. Novel heterocyclic compounds as bromodomain inhibitors
EP2801357A1 (en) * 2013-05-10 2014-11-12 IMD Natural Solutions GmbH Carboxylated stilbenes for activating AMPK and sirtuins
CN103992290B (en) * 2013-05-14 2016-07-06 中国医学科学院医药生物技术研究所 Diarylethene structurally similar compounds and its preparation method and application
CN104547001A (en) * 2015-01-09 2015-04-29 刘长河 Process for extracting anti-osteoporosis and lipid-decreasing substances from pigeon pea leaves
US10111885B2 (en) 2015-03-13 2018-10-30 Resverlogix Corp. Compositions and therapeutic methods for the treatment of complement-associated diseases
EP3641564B1 (en) * 2017-06-22 2024-05-22 Symrise AG Taste modulating flavoring substances
CN112175856B (en) * 2019-07-05 2022-10-21 中粮生物科技股份有限公司 Solid culture medium for bacillus subtilis fermentation, bacillus subtilis solid microbial inoculum and preparation method and application thereof
JP2023547641A (en) * 2020-11-05 2023-11-13 ソシエテ・デ・プロデュイ・ネスレ・エス・アー Substituted resorcylic acid compounds and their use as AMPK activators

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62270529A (en) * 1986-05-19 1987-11-24 Nippon Haipotsukusu:Kk Antiallergic agent
US5827898A (en) 1996-10-07 1998-10-27 Shaman Pharmaceuticals, Inc. Use of bisphenolic compounds to treat type II diabetes
FR2778337B1 (en) 1998-05-05 2001-08-31 Inst Nat Sante Rech Med ARYLHYDROCARBON RECEPTOR LIGAND ANTAGONISTS
AU767245B2 (en) 1998-11-25 2003-11-06 Nutri Pharma Asa Composition comprising soy protein, dietary fibres and a phytoestrogen compound and use thereof in the prevention and/or treatment of cardiovascular diseases
DE10015525A1 (en) 2000-03-30 2001-10-11 Deutsches Krebsforsch Synthetic derivatives of lunular acid, medicaments containing this compound, process for the preparation of lunular acid derivatives and their use
US20020058708A1 (en) 2000-08-16 2002-05-16 Inman Wayne D. Compositions containing hypotriglyceridemically active stilbenoids
US6552085B2 (en) 2000-08-16 2003-04-22 Insmed Incorporated Compositions containing hypoglycemically active stilbenoids
US6410596B1 (en) 2000-08-16 2002-06-25 Insmed Incorporated Compositions containing hypoglycemically active stillbenoids

Also Published As

Publication number Publication date
WO2002013806A2 (en) 2002-02-21
DE60109938D1 (en) 2005-05-12
EP1311258A2 (en) 2003-05-21
US6541522B2 (en) 2003-04-01
WO2002013806A3 (en) 2002-10-31
ATE292460T1 (en) 2005-04-15
US20020055541A1 (en) 2002-05-09
DE60109938T2 (en) 2005-09-08
EP1311258B1 (en) 2005-04-06

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