AU2001282785A1 - A sample collecting arrangement and a method - Google Patents

A sample collecting arrangement and a method

Info

Publication number
AU2001282785A1
AU2001282785A1 AU2001282785A AU8278501A AU2001282785A1 AU 2001282785 A1 AU2001282785 A1 AU 2001282785A1 AU 2001282785 A AU2001282785 A AU 2001282785A AU 8278501 A AU8278501 A AU 8278501A AU 2001282785 A1 AU2001282785 A1 AU 2001282785A1
Authority
AU
Australia
Prior art keywords
sample collecting
collecting arrangement
arrangement
sample
collecting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001282785A
Inventor
Anatol Krozer
Robert P. Otillar
Britta Ottosson
Niklaus Schneeberger
David Storek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imego AB
Original Assignee
Imego AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0002990A external-priority patent/SE0002990L/en
Application filed by Imego AB filed Critical Imego AB
Publication of AU2001282785A1 publication Critical patent/AU2001282785A1/en
Abandoned legal-status Critical Current

Links

Classifications

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    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093Microreactors, e.g. miniaturised or microfabricated reactors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50853Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/035Open gradient magnetic separators, i.e. separators in which the gap is unobstructed, characterised by the configuration of the gap
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • G01N33/54333Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
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    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00306Reactor vessels in a multiple arrangement
    • B01J2219/00313Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315Microtiter plates
    • B01J2219/00317Microwell devices, i.e. having large numbers of wells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00331Details of the reactor vessels
    • B01J2219/00333Closures attached to the reactor vessels
    • B01J2219/00337Valves
    • B01J2219/0034Valves in the shape of a ball or sphere
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00277Apparatus
    • B01J2219/00351Means for dispensing and evacuation of reagents
    • B01J2219/00436Maskless processes
    • B01J2219/00439Maskless processes using micromirror arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01J2219/00277Apparatus
    • B01J2219/00457Dispensing or evacuation of the solid phase support
    • B01J2219/00459Beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/005Beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00585Parallel processes
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
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    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/0059Sequential processes
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    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00596Solid-phase processes
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00608DNA chips
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01J2219/00612Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
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    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00614Delimitation of the attachment areas
    • B01J2219/00621Delimitation of the attachment areas by physical means, e.g. trenches, raised areas
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00646Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports
    • B01J2219/00648Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports by the use of solid beads
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    • B01J2219/0072Organic compounds
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    • B01J2219/00783Laminate assemblies, i.e. the reactor comprising a stack of plates
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6825Nucleic acid detection involving sensors
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
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    • C40B40/04Libraries containing only organic compounds
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    • CCHEMISTRY; METALLURGY
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    • C40B60/14Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
AU2001282785A 2000-08-23 2001-08-23 A sample collecting arrangement and a method Abandoned AU2001282785A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
SE0002990 2000-08-23
SE0002990A SE0002990L (en) 2000-08-23 2000-08-23 An arrangement for sample preparation and a method for such an arrangement
US22801500P 2000-08-24 2000-08-24
US60228015 2000-08-24
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Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7188731B2 (en) 2002-08-26 2007-03-13 The Regents Of The University Of California Variable flexure-based fluid filter
US7300631B2 (en) * 2005-05-02 2007-11-27 Bioscale, Inc. Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles
US7648844B2 (en) 2005-05-02 2010-01-19 Bioscale, Inc. Method and apparatus for detection of analyte using an acoustic device
US7749445B2 (en) 2005-05-02 2010-07-06 Bioscale, Inc. Method and apparatus for analyzing bioprocess fluids
DE102005054923B3 (en) * 2005-11-17 2007-04-12 Siemens Ag Device for preparing a sample used in biotechnology stores the working reagents in dry form embedded in a biologically degradable medium which is water-tight in the non-degraded state
WO2007106579A2 (en) 2006-03-15 2007-09-20 Micronics, Inc. Integrated nucleic acid assays
JP5438506B2 (en) * 2006-05-10 2014-03-12 コーニンクレッカ フィリップス エヌ ヴェ Magnetic system
US7807454B2 (en) 2006-10-18 2010-10-05 The Regents Of The University Of California Microfluidic magnetophoretic device and methods for using the same
WO2008067103A2 (en) * 2006-10-30 2008-06-05 Stc.Unm Magnetically susceptible particles and apparatuses for mixing the same
ATE554859T1 (en) * 2007-05-24 2012-05-15 Univ California INTEGRATED FLUIDIC DEVICES WITH MAGNETIC SORTING
EP2034324A3 (en) * 2007-07-20 2010-06-16 Koninklijke Philips Electronics N.V. Sensor cartridge
GB2464433B (en) * 2007-08-23 2012-06-20 Cynvenio Biosystems Llc Trapping magnetic sorting system for target species
WO2009033056A1 (en) 2007-09-06 2009-03-12 Bioscale, Inc. Reusable detection surfaces and methods of using same
WO2009117611A2 (en) * 2008-03-19 2009-09-24 Cynvenio Biosystems, Llc Trapping magnetic cell sorting system
EP2271919A1 (en) * 2008-04-16 2011-01-12 Cynvenio Biosystems, Inc. Magnetic separation system with pre and post processing modules
US10407660B2 (en) 2010-08-10 2019-09-10 Greiner Bio-One North America, Inc. Hardware for magnetic 3D culture
WO2013019212A1 (en) * 2011-08-02 2013-02-07 Nano3D Biosciences, Inc. Hardware for magnetic 3d culture
GB2463401B (en) 2008-11-12 2014-01-29 Caris Life Sciences Luxembourg Holdings S A R L Characterizing prostate disorders by analysis of microvesicles
CN102713640B (en) * 2009-06-10 2015-09-16 辛温尼奥生物***公司 Sheath stream apparatus and method
GB2477506B (en) * 2010-02-03 2013-10-30 Dna Electronics Ltd Integrated electrochemical and optical sensor with inductor
CA2791905A1 (en) 2010-03-01 2011-09-09 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Biomarkers for theranostics
KR101067695B1 (en) * 2010-03-25 2011-09-27 충남대학교산학협력단 Micro magnetic device for biomolecule translocation
AU2011237669B2 (en) 2010-04-06 2016-09-08 Caris Life Sciences Switzerland Holdings Gmbh Circulating biomarkers for disease
US10942184B2 (en) 2012-10-23 2021-03-09 Caris Science, Inc. Aptamers and uses thereof
BR112015009138A2 (en) 2012-10-23 2020-10-20 Caris Life Sciences Switzerland Holdings, S.A.R.L. methods for characterizing cancer
EP2935628B1 (en) 2012-12-19 2018-03-21 Caris Life Sciences Switzerland Holdings GmbH Compositions and methods for aptamer screening
EP3039174B1 (en) 2013-08-28 2019-10-16 Caris Science, Inc. Oligonucleotide probes and uses thereof
EP3042722B1 (en) * 2015-01-07 2019-11-27 Personal Genomics Inc. Oriented loading systems and method for orienting a particle loaded in a well
US20180066262A1 (en) 2015-03-09 2018-03-08 Caris Science, Inc. Oligonucleotide probes and uses thereof
EP3314027A4 (en) 2015-06-29 2019-07-03 Caris Science, Inc. Therapeutic oligonucleotides
AU2016298317B2 (en) 2015-07-28 2021-02-18 Caris Science, Inc. Targeted oligonucleotides
CN109715802A (en) 2016-03-18 2019-05-03 卡里斯科学公司 Oligonucleotide probe and application thereof
US11293017B2 (en) 2016-05-25 2022-04-05 Caris Science, Inc. Oligonucleotide probes and uses thereof
WO2018175500A1 (en) 2017-03-21 2018-09-27 Hexanomics, Inc. Sealed microwell assay
US10498001B2 (en) 2017-08-21 2019-12-03 Texas Instruments Incorporated Launch structures for a hermetically sealed cavity
US10775422B2 (en) 2017-09-05 2020-09-15 Texas Instruments Incorporated Molecular spectroscopy cell with resonant cavity
US10589986B2 (en) 2017-09-06 2020-03-17 Texas Instruments Incorporated Packaging a sealed cavity in an electronic device
US10131115B1 (en) 2017-09-07 2018-11-20 Texas Instruments Incorporated Hermetically sealed molecular spectroscopy cell with dual wafer bonding
US10424523B2 (en) 2017-09-07 2019-09-24 Texas Instruments Incorporated Hermetically sealed molecular spectroscopy cell with buried ground plane
US10444102B2 (en) 2017-09-07 2019-10-15 Texas Instruments Incorporated Pressure measurement based on electromagnetic signal output of a cavity
US10551265B2 (en) 2017-09-07 2020-02-04 Texas Instruments Incorporated Pressure sensing using quantum molecular rotational state transitions
US10549986B2 (en) 2017-09-07 2020-02-04 Texas Instruments Incorporated Hermetically sealed molecular spectroscopy cell
US10544039B2 (en) * 2017-09-08 2020-01-28 Texas Instruments Incorporated Methods for depositing a measured amount of a species in a sealed cavity
MX2021006234A (en) 2018-11-30 2021-09-10 Caris Mpi Inc Next-generation molecular profiling.
WO2020140204A1 (en) * 2019-01-02 2020-07-09 京东方科技集团股份有限公司 Microfluidic device and detection method therefor, and microfluidic detection assembly
EP4069865A4 (en) 2019-12-02 2023-12-20 Caris MPI, Inc. Pan-cancer platinum response predictor
US20230133866A1 (en) * 2020-04-09 2023-05-04 SiPhox Inc. Integrated photonic systems and methods for biosensing

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4414243A (en) * 1982-07-06 1983-11-08 General Electric Company Method for making surface acoustic wave devices
US4822566A (en) * 1985-11-19 1989-04-18 The Johns Hopkins University Optimized capacitive sensor for chemical analysis and measurement
US4932255A (en) * 1988-12-16 1990-06-12 Johnson Service Company Flow sensing using surface acoustic waves
AU6354190A (en) * 1989-08-21 1991-04-03 Board Of Regents Of The University Of Washington, The Multiple-probe diagnostic sensor
US5235235A (en) * 1991-05-24 1993-08-10 The United States Of America As Represented By The United States Department Of Energy Multiple-frequency acoustic wave devices for chemical sensing and materials characterization in both gas and liquid phase
GB9410426D0 (en) * 1994-05-25 1994-07-13 Stevenson Adrian C Acoustic monitor assembly
US5585069A (en) * 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
US5655665A (en) * 1994-12-09 1997-08-12 Georgia Tech Research Corporation Fully integrated micromachined magnetic particle manipulator and separator
AU4927496A (en) * 1995-02-21 1996-09-11 Iqbal W. Siddiqi Apparatus and method for mixing and separation employing magnetic particles
US5545531A (en) 1995-06-07 1996-08-13 Affymax Technologies N.V. Methods for making a device for concurrently processing multiple biological chip assays
US5814525A (en) * 1996-01-25 1998-09-29 Sandia Corporation Piezoelectric biosensor with a ladder polymer substrate coating
US6358752B1 (en) * 1996-09-27 2002-03-19 Cornell Research Foundation, Inc. Liposome-enhanced test device and method
US6468806B1 (en) * 1996-10-02 2002-10-22 Symyx Technologies, Inc. Potential masking systems and methods for combinatorial library synthesis
US5922537A (en) * 1996-11-08 1999-07-13 N.o slashed.AB Immunoassay, Inc. Nanoparticles biosensor
US5981297A (en) * 1997-02-05 1999-11-09 The United States Of America As Represented By The Secretary Of The Navy Biosensor using magnetically-detected label
US5922617A (en) 1997-11-12 1999-07-13 Functional Genetics, Inc. Rapid screening assay methods and devices
FI102906B1 (en) * 1998-02-23 1999-03-15 Bio Nobile Oy Process and means for transporting a substance
US6161437A (en) * 1998-04-09 2000-12-19 Georgia Tech Research Corporation Method and apparatus for evaluating an analyte
FR2781886B1 (en) 1998-07-31 2001-02-16 Commissariat Energie Atomique MULTIPLE POINT CHEMICAL OR BIOLOGICAL ANALYSIS MICROSYSTEM
US6572830B1 (en) * 1998-10-09 2003-06-03 Motorola, Inc. Integrated multilayered microfludic devices and methods for making the same
CA2360748A1 (en) * 1999-01-19 2000-07-27 Larry Gold Method and apparatus for the automated generation of nucleic acid ligands
US20050148101A1 (en) * 1999-01-23 2005-07-07 Bamdad Cynthia C. Interaction of colloid-immobilized species with species on non-colloidal structures
CA2359901A1 (en) * 1999-02-16 2000-08-24 Pe Corporation (Ny) Bead dispensing system
CN1185492C (en) * 1999-03-15 2005-01-19 清华大学 Single-point strobed micro electromagnetic units array chip or electromagnetic biologic chip and application thereof
CA2368773A1 (en) * 1999-04-01 2000-10-12 Cellomics, Inc. Miniaturized cell array methods and apparatus for cell-based screening
AU4244300A (en) * 1999-04-13 2000-11-14 Nanogen, Inc. Magnetic bead-based array for genetic detection
US6468809B1 (en) * 2000-02-04 2002-10-22 The United States Of America As Represented By The Secretary Of The Navy High efficiency magnetic sensor for magnetic particles
WO2001071034A2 (en) * 2000-03-22 2001-09-27 President And Fellows Of Harvard College Methods and apparatus for parallel magnetic biological analysis and manipulation
US7585682B2 (en) * 2000-10-03 2009-09-08 Minerva Biotechologies Corporation Magnetic in situ dilution

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AU2001282786A1 (en) 2002-03-04
WO2002016904A3 (en) 2002-05-23
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EP1311854A2 (en) 2003-05-21

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