AU2001278135A1 - Method of identifying immunosuppressive agents - Google Patents
Method of identifying immunosuppressive agentsInfo
- Publication number
- AU2001278135A1 AU2001278135A1 AU2001278135A AU7813501A AU2001278135A1 AU 2001278135 A1 AU2001278135 A1 AU 2001278135A1 AU 2001278135 A AU2001278135 A AU 2001278135A AU 7813501 A AU7813501 A AU 7813501A AU 2001278135 A1 AU2001278135 A1 AU 2001278135A1
- Authority
- AU
- Australia
- Prior art keywords
- immunosuppressive agents
- identifying immunosuppressive
- identifying
- agents
- immunosuppressive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 229940125721 immunosuppressive agent Drugs 0.000 title 1
- 239000003018 immunosuppressive agent Substances 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22289700P | 2000-08-03 | 2000-08-03 | |
US60/222,897 | 2000-08-03 | ||
PCT/US2001/024250 WO2002012545A2 (en) | 2000-08-03 | 2001-08-02 | Method of identifying immunosuppressive agents |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001278135A1 true AU2001278135A1 (en) | 2002-02-18 |
Family
ID=22834184
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001278135A Abandoned AU2001278135A1 (en) | 2000-08-03 | 2001-08-02 | Method of identifying immunosuppressive agents |
Country Status (3)
Country | Link |
---|---|
US (1) | US6828091B2 (en) |
AU (1) | AU2001278135A1 (en) |
WO (1) | WO2002012545A2 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6342611B1 (en) * | 1997-10-10 | 2002-01-29 | Cytovia, Inc. | Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof |
US7053117B2 (en) * | 2001-05-16 | 2006-05-30 | Cytovia, Inc. | Substituted 4H-chromenes and analogs as activators of caspases and inducers of apoptosis and the use thereof |
AU2001278135A1 (en) | 2000-08-03 | 2002-02-18 | Cytovia, Inc. | Method of identifying immunosuppressive agents |
AU2003230411A1 (en) | 2002-05-16 | 2003-12-02 | Cytovia, Inc. | Substituted 4-aryl-4h-pyrrolo(2,3-h)chromenes and analogs as activators of caspases and inducers of apoptosis and the use thereof |
WO2003096982A2 (en) * | 2002-05-16 | 2003-11-27 | Cytovia, Inc. | Substituted 4h-chromenes, 2h-chromenes, chromans and analogs as activators of caspases and inducers of apoptosis and the use thereof |
US7067266B2 (en) * | 2002-07-10 | 2006-06-27 | Rigel Pharmaceuticals, Inc. | Modulators of leukocyte activation, Hck compositions and methods of use |
WO2005100553A2 (en) * | 2004-04-16 | 2005-10-27 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Method for assessment of cytotoxic lymphocyte activity |
CN101289482B (en) | 2007-09-29 | 2011-08-31 | 辽宁利锋科技开发有限公司 | Cambogic acid glycoside derivates and the like, preparation and uses thereof |
PT2278960T (en) | 2008-03-17 | 2017-03-09 | Actelion Pharmaceuticals Ltd | Dosing regimen for a selective sip1 receptor agonist |
KR101821118B1 (en) | 2016-09-06 | 2018-01-23 | 가톨릭대학교 산학협력단 | Composition for Preventing or Treating Allergic Disease Comprising Gambogic Acid |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4336186A (en) | 1978-08-03 | 1982-06-22 | Gargiulo Robert J | Analytical fluorogenic substrates for proteolytic enzymes |
US4557862A (en) | 1983-10-28 | 1985-12-10 | University Patents, Inc. | Rhodamine derivatives as fluorogenic substrates for proteinases |
US4640893A (en) | 1983-10-28 | 1987-02-03 | University Of Illinois | Novel rhodamine derivatives as fluorogenic substrates for proteinases |
US4900686A (en) | 1987-04-02 | 1990-02-13 | Polaroid Corporation | Fluorescent conjugates and biological diagnostic assay |
US5227487A (en) | 1990-04-16 | 1993-07-13 | Molecular Probes, Inc. | Certain tricyclic and pentacyclic-hetero nitrogen rhodol dyes |
US5587490A (en) | 1990-04-16 | 1996-12-24 | Credit Managers Association Of California | Method of inactivation of viral and bacterial blood contaminants |
US5208148A (en) | 1990-12-07 | 1993-05-04 | Molecular Probes, Inc. | Lipophilic fluorescent glycosidase substrates |
ATE180018T1 (en) | 1991-08-23 | 1999-05-15 | Molecular Probes Inc | USE OF HALOALKYL DERIVATIVES OF REPORTER MOLECULES FOR ANALYZING METABOLIC ACTIVITY IN CELLS |
US5316906A (en) | 1991-08-23 | 1994-05-31 | Molecular Probes, Inc. | Enzymatic analysis using substrates that yield fluorescent precipitates |
US5576424A (en) | 1991-08-23 | 1996-11-19 | Molecular Probes, Inc. | Haloalkyl derivatives of reporter molecules used to analyze metabolic activity in cells |
WO1993010461A1 (en) | 1991-11-12 | 1993-05-27 | Promega Corporation | Non-radioactive enzyme assay |
US5696128A (en) | 1994-07-07 | 1997-12-09 | The Board Of Supervisors Of Louisiana University And Agricultural And Mechanical College | Method of regulating immune function |
EP0623599A1 (en) | 1993-03-26 | 1994-11-09 | Ciba-Geigy Ag | Optical sensors for the determination of cations |
US6087160A (en) | 1993-06-24 | 2000-07-11 | The General Hospital Corporation | Programmed cell death genes and proteins |
US5659024A (en) | 1994-01-14 | 1997-08-19 | The Burnham Institute | Promotors that regulate the expression of genes involved in cell death |
US5556992A (en) | 1994-09-02 | 1996-09-17 | Universite De Montreal | Novel rhodamine derivatives for photodynamic therapy of cancer and in vitro purging of the leukemias |
US5605809A (en) | 1994-10-28 | 1997-02-25 | Oncoimmunin, Inc. | Compositions for the detection of proteases in biological samples and methods of use thereof |
US5843635A (en) | 1995-02-27 | 1998-12-01 | Dana-Farber Cancer Institute, Inc. | Inhibition of APC-mediated apoptosis of activated T lymphocytes |
US5733719A (en) | 1995-05-18 | 1998-03-31 | Coulter Corporation | Method of making an assay compound |
US5698411A (en) | 1995-05-18 | 1997-12-16 | Coulter Corporation | Method for determining activity of enzymes in metabolically active whole cells |
US5976822A (en) | 1995-05-18 | 1999-11-02 | Coulter International Corp. | Method and reagent for monitoring apoptosis and distinguishing apoptosis from necrosis |
US5776720A (en) | 1995-05-18 | 1998-07-07 | Coulter Corporation | Assay reagent |
US5871946A (en) | 1995-05-18 | 1999-02-16 | Coulter Corporation | Method for determining activity of enzymes in metabolically active whole cells |
US5834216A (en) | 1995-09-06 | 1998-11-10 | Arch Development Corporation | Screening methods for the identification of inducers and inhibitors of programmed cell death (apoptosis) |
US6200969B1 (en) | 1996-09-12 | 2001-03-13 | Idun Pharmaceuticals, Inc. | Inhibition of apoptosis using interleukin-1β-converting enzyme (ICE)/CED-3 family inhibitors |
US5897992A (en) | 1996-09-27 | 1999-04-27 | Cold Spring Harbor Laboratory | Cell-free assay using oncogene-induced apoptosis in drug-resistant cells |
US6077684A (en) | 1996-11-14 | 2000-06-20 | Vanderbilt University | Automated assay for measuring apoptosis in cell culture |
US5773236A (en) | 1997-04-25 | 1998-06-30 | Molecule Probes, Inc. | Assay for glutathiane transferase using polyhaloaryl-substituted reporter molecules |
US6270980B1 (en) | 1997-06-05 | 2001-08-07 | Idun Pharmaceuticals, Inc. | Rapid methods for identifying modifiers of cellular apoptosis activity |
WO1998057664A1 (en) | 1997-06-19 | 1998-12-23 | The General Hospital Corporation | Interleukin converting enzyme (ice) and central nervous system damage |
US6342611B1 (en) | 1997-10-10 | 2002-01-29 | Cytovia, Inc. | Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof |
HUP0100079A2 (en) | 1997-10-10 | 2001-05-28 | Cytovia, Inc. | Novel fluorescent reporter molecules and their applications including assays for caspases |
AU5116099A (en) | 1998-07-21 | 2000-02-14 | Sui Xiong Cai | Novel fluorescence dyes and their applications for whole cell fluorescence screening assays for caspases, peptidases, proteases and other enzymes and the use thereof |
WO2000007017A2 (en) | 1998-07-27 | 2000-02-10 | President And Fellows Of Harvard College | Method of high-throughput screening |
AU2864100A (en) | 1999-02-01 | 2000-08-18 | Cytovia, Inc. | Methods of identifying therapeutically effective antineoplastic agents with cultured cells having intact cell membranes and corresponding products |
CA2406271A1 (en) | 2000-04-18 | 2001-10-25 | Cytovia, Inc. | Substituted 1,4-thiazepine and analogs and their use as activators of caspases |
AU2001278135A1 (en) | 2000-08-03 | 2002-02-18 | Cytovia, Inc. | Method of identifying immunosuppressive agents |
WO2002099378A2 (en) | 2001-06-01 | 2002-12-12 | Cytovia, Inc. | Methods of identifying anti-cancer agents that are inducers of apoptosis |
-
2001
- 2001-08-02 AU AU2001278135A patent/AU2001278135A1/en not_active Abandoned
- 2001-08-02 WO PCT/US2001/024250 patent/WO2002012545A2/en active Application Filing
- 2001-08-02 US US09/920,332 patent/US6828091B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6828091B2 (en) | 2004-12-07 |
WO2002012545A2 (en) | 2002-02-14 |
US20020076733A1 (en) | 2002-06-20 |
WO2002012545A3 (en) | 2002-08-01 |
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