AU2001276682A1 - Sugar absorption inhibitors and process for producing the same - Google Patents

Sugar absorption inhibitors and process for producing the same

Info

Publication number
AU2001276682A1
AU2001276682A1 AU2001276682A AU7668201A AU2001276682A1 AU 2001276682 A1 AU2001276682 A1 AU 2001276682A1 AU 2001276682 A AU2001276682 A AU 2001276682A AU 7668201 A AU7668201 A AU 7668201A AU 2001276682 A1 AU2001276682 A1 AU 2001276682A1
Authority
AU
Australia
Prior art keywords
evening primrose
primrose seed
aforementioned
defatted
absorption inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001276682A
Inventor
Michio Aitani
Tsutomu Arimura
Yotaro Konishi
Hiromichi Murai
Tadashi Okada
Hiroshi Yamaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oryza Oil and Fat Chemical Co Ltd
Original Assignee
Oryza Oil and Fat Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oryza Oil and Fat Chemical Co Ltd filed Critical Oryza Oil and Fat Chemical Co Ltd
Publication of AU2001276682A1 publication Critical patent/AU2001276682A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Saccharide Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

This invention provides carbohydrate absorption inhibitor derived from evening primrose seed which is significantly effective to prevent and cure diabetes mellitus and prevent obesity, and the manufacturing method of the same. Carbohydrate absorption inhibitor in this invention is characterized that the effective component is an alcohol extract of evening primrose seed. The aforementioned evening primrose seed is preferably a defatted evening primrose seed. Extracting solvent of the aforementioned evening primrose seed is preferably ethanol, or preferably a 70 to 85% (v/v) aqueous ethanol. Also, this invention is characterized that the carbohydrate absorption inhibitor is an effective component of polyphenol derived from evening primrose seed. The polyphenol is preferably one or more substances selected from among gallic acid, ellagic acid, catechin, pentagalloylglucose, procyanidin, and proantocyanidin. The manufacturing method of the carbohydrate absorption inhibitor in this invention is characterized to be composed of the following processes A to C. Process A: evening primrose is compressed, oil is separated then the compressed cake is obtained. Process B: The aforementioned compressed cake is defatted in fat-soluble organic solvent, and defatted substance is obtained. Process C: The aforementioned defatted substance is extracted by alcohol, and then this extracted liquid is concentrated or evaporated. <IMAGE>
AU2001276682A 2000-08-01 2001-07-26 Sugar absorption inhibitors and process for producing the same Abandoned AU2001276682A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000232930 2000-08-01
JP2000-232930 2000-08-01
PCT/JP2001/006436 WO2002009734A1 (en) 2000-08-01 2001-07-26 Sugar absorption inhibitors and process for producing the same

Publications (1)

Publication Number Publication Date
AU2001276682A1 true AU2001276682A1 (en) 2002-02-13

Family

ID=18725531

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001276682A Abandoned AU2001276682A1 (en) 2000-08-01 2001-07-26 Sugar absorption inhibitors and process for producing the same

Country Status (8)

Country Link
US (2) US6932990B2 (en)
EP (1) EP1312374B1 (en)
JP (1) JP4873824B2 (en)
CN (1) CN1268351C (en)
AT (1) ATE407689T1 (en)
AU (1) AU2001276682A1 (en)
DE (1) DE60135760D1 (en)
WO (1) WO2002009734A1 (en)

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US20020035071A1 (en) * 1997-07-08 2002-03-21 Josef Pitha Mimicking the metabolic effects of caloric restriction by administration of glucose antimetabolites
US8563522B2 (en) * 1997-07-08 2013-10-22 The Iams Company Method of maintaining and/or attenuating a decline in quality of life
US7713546B1 (en) 2001-04-03 2010-05-11 Soft Gel Technologies, Inc. Corosolic acid formulation and its application for weight-loss management and blood sugar balance
US7666459B2 (en) 2001-09-12 2010-02-23 The Procter & Gamble Company Pet food compositions
KR20030075947A (en) * 2002-03-19 2003-09-26 제네티카 주식회사 Angiogenesis inhibitor
EP1545554A4 (en) * 2002-07-24 2006-06-14 Univ Ohio Methods and compositions for treating diabetes mellitis
JP4541662B2 (en) * 2003-05-29 2010-09-08 オリザ油化株式会社 Anti-pylori composition
GB0321996D0 (en) * 2003-09-19 2003-10-22 Novartis Nutrition Ag Organic compounds
JP2006335758A (en) * 2003-10-06 2006-12-14 Oriza Yuka Kk Composition for diet
CN1863543B (en) * 2003-10-06 2010-06-16 奥力榨油化株式会社 Dietetic composition
US8877178B2 (en) 2003-12-19 2014-11-04 The Iams Company Methods of use of probiotic bifidobacteria for companion animals
US20050158294A1 (en) 2003-12-19 2005-07-21 The Procter & Gamble Company Canine probiotic Bifidobacteria pseudolongum
EP1557094A1 (en) * 2004-01-26 2005-07-27 Wageningen Centre for Food Sciences Improved semi-solid food products and methods for their production based on inhibiting amylase induced starch breakdown
US20050251265A1 (en) * 2004-05-07 2005-11-10 Calandruccio James H Trapezium implant for thumb and method
US20050249837A1 (en) * 2004-05-10 2005-11-10 The Procter & Gamble Company Processes for preparing plant matter extracts and pet food compositions
US20090252834A1 (en) * 2004-05-10 2009-10-08 Michael Griffin Hayek Compositions comprising glucose anti-metabolites
CN101001539B (en) * 2004-06-04 2012-05-30 视界科技有限公司 Natural sweetener
JP5020462B2 (en) * 2004-06-16 2012-09-05 クラシエフーズ株式会社 α-Glucosidase inhibitor and food using the same
JP2006016330A (en) * 2004-06-30 2006-01-19 Suntory Ltd Fat-burning accelerating agent
US20060051435A1 (en) * 2004-08-19 2006-03-09 Udell Ronald G Nutritional supplement for body fat reduction
JP2006056850A (en) * 2004-08-23 2006-03-02 Suntory Ltd Lipase inhibitor
EP1788390B1 (en) * 2004-08-30 2010-04-14 Takeda Pharmaceutical Company Limited Screening method
JP2006104181A (en) * 2004-09-13 2006-04-20 Takahiro Tsujita Glucide-splitting enzyme-inhibiting material derived from fagaceae plant and application thereof
CN100566723C (en) * 2004-09-13 2009-12-09 辻田隆广 Carbohydrase inhibitor and application thereof derived from the acorn-cup plant
CA2609617C (en) 2005-05-31 2014-07-08 The Iams Company Feline probiotic lactobacilli
BRPI0611492B1 (en) 2005-05-31 2021-10-13 Mars, Incorporated BIFIDOBACTERIA PROBIOTICS FELINE
AU2006254652B2 (en) 2005-06-03 2011-04-21 Poly Gain Pte Ltd Substances having body mass redistribution properties
WO2007019526A2 (en) * 2005-08-05 2007-02-15 Naturegen, Inc. Compositions and methods for controlling glucose and lipid uptake from foods
KR100829083B1 (en) 2006-07-28 2008-05-16 재단법인 제주하이테크산업진흥원 Oenothera laciniata extracts having physiological activity
AU2007299581B2 (en) * 2006-09-19 2011-04-28 Poly Gain Pte Ltd Extracts derived from sugar cane and a process for their manufacture
MX2009008165A (en) * 2007-02-01 2009-08-12 Iams Company Method for decreasing inflammation and oxidative stress in mammals.
JP5799299B2 (en) * 2007-02-01 2015-10-21 ザ・アイムス・カンパニーＴｈｅ Ｉａｍｓ Ｃｏｍｐａｎｙ Method for reducing inflammation and stress in mammals using glucose antimetabolite, avocado or avocado extract
WO2009137859A1 (en) 2008-05-15 2009-11-19 Alois Jungbauer Compounds for the treatment of metabolic syndrome and insulin resistance
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
GB2475657B (en) * 2008-08-22 2013-05-29 Relypsa Inc Crosslinked cation exchange polymers, compositions and use in treating hyperkalemia
CN102170890B (en) * 2008-10-08 2013-03-20 百佳株式会社 Anti-avian influenza virus agent, and product containing anti-avian influenza virus agent
JP2010184909A (en) * 2009-02-13 2010-08-26 Rheology Kino Shokuhin Kenkyusho:Kk Functional composition and pharmaceutical or health food comprising the composition
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
CN102018766B (en) 2009-09-16 2013-03-06 博仲盛景医药技术（北京）有限公司 Plant extractive, extraction method and application thereof as well as composite comprising same
CA2860448C (en) 2011-02-08 2019-09-10 Horizon Science Pty Ltd Molasses extract enriched in polyphenols and uses thereof
RU2451506C1 (en) * 2011-06-02 2012-05-27 Сергей Юрьевич Лешков Combination for treatment of diabetes and complications thereof
CN104780987B (en) 2012-08-28 2018-10-30 产品制造商（澳大利亚）有限公司 extracting method
JP2014198684A (en) * 2013-03-29 2014-10-23 サンスター株式会社 Blood sugar metabolism improver
CN105722520A (en) 2013-08-16 2016-06-29 产品制造商（澳大利亚）有限公司 Sugar cane derived extracts and methods of treatment
JP6998108B2 (en) 2016-03-07 2022-01-18 株式会社ダイセル Α-Glucosidase activity inhibitor containing urolithins and blood glucose increase inhibitor containing urolithins
CA3086827A1 (en) * 2017-12-27 2019-07-04 Suntory Holdings Limited Composition for improving intestinal barrier function
JPWO2022085602A1 (en) * 2020-10-20 2022-04-28

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JP3018013B2 (en) * 1989-10-19 2000-03-13 三井農林株式会社 α-amylase activity inhibitor
JPH09176019A (en) * 1995-12-26 1997-07-08 Suntory Ltd Carbohydrate-degradative/digestive enzyme inhibitor and medicine and food/beverage formulated therewith
PT815857E (en) 1995-12-26 2005-01-31 Suntory Ltd ANTI-OBESITY AGENT PROCIANIDIN AS ACTIVE INGREDIENT
AU9369198A (en) * 1998-09-30 2000-04-17 Industrial Research Limited Antioxidant compositions and process for their preparation

Also Published As

Publication number Publication date
EP1312374A4 (en) 2004-04-21
EP1312374B1 (en) 2008-09-10
JP4873824B2 (en) 2012-02-08
CN1268351C (en) 2006-08-09
WO2002009734A8 (en) 2002-02-28
EP1312374A1 (en) 2003-05-21
ATE407689T1 (en) 2008-09-15
US20060024396A1 (en) 2006-02-02
DE60135760D1 (en) 2008-10-23
US20030161903A1 (en) 2003-08-28
CN1468106A (en) 2004-01-14
WO2002009734A1 (en) 2002-02-07
US6932990B2 (en) 2005-08-23

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