AU2001275537A1 - N-and o-substituted 4-(2-(diphenylmethoxy)-ethyl)-1-((phenyl)methyl)piperidine analogs and methods of treating cns disorders therewith - Google Patents
N-and o-substituted 4-(2-(diphenylmethoxy)-ethyl)-1-((phenyl)methyl)piperidine analogs and methods of treating cns disorders therewithInfo
- Publication number
- AU2001275537A1 AU2001275537A1 AU2001275537A AU7553701A AU2001275537A1 AU 2001275537 A1 AU2001275537 A1 AU 2001275537A1 AU 2001275537 A AU2001275537 A AU 2001275537A AU 7553701 A AU7553701 A AU 7553701A AU 2001275537 A1 AU2001275537 A1 AU 2001275537A1
- Authority
- AU
- Australia
- Prior art keywords
- diphenylmethoxy
- phenyl
- ethyl
- substituted
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21292100P | 2000-06-20 | 2000-06-20 | |
US60212921 | 2000-06-20 | ||
PCT/US2001/040964 WO2001098266A2 (en) | 2000-06-20 | 2001-06-14 | N-and o-substituted 4-[2-(diphenylmethoxy)-ethyl]-1-[(phenyl)methyl]piperidine analogs and methods of treating cns disorders therewith |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001275537A1 true AU2001275537A1 (en) | 2002-01-02 |
Family
ID=22792949
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001275537A Abandoned AU2001275537A1 (en) | 2000-06-20 | 2001-06-14 | N-and o-substituted 4-(2-(diphenylmethoxy)-ethyl)-1-((phenyl)methyl)piperidine analogs and methods of treating cns disorders therewith |
Country Status (3)
Country | Link |
---|---|
US (3) | US6995268B2 (en) |
AU (1) | AU2001275537A1 (en) |
WO (1) | WO2001098266A2 (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003523408A (en) * | 2000-02-22 | 2003-08-05 | バイオストリーム インク | Imaging agents for diagnosing Parkinson's disease |
AU2001275537A1 (en) * | 2000-06-20 | 2002-01-02 | Wayne State University | N-and o-substituted 4-(2-(diphenylmethoxy)-ethyl)-1-((phenyl)methyl)piperidine analogs and methods of treating cns disorders therewith |
US8211916B2 (en) * | 2000-06-20 | 2012-07-03 | Wayne State University | N- and O-substituted 4-[2-(diphenylmethoxy)-ethyl]-1-[(phenyl)methyl]piperidine analogs and methods of treating CNS disorders therewith |
US20060122263A1 (en) * | 2003-03-28 | 2006-06-08 | Dutta Aloke K | Tri-substituted 2-benzhydryl-5-benzlamino-tetrahydro-pyran-4-ol and 6-benzhydryl-4-benzylamino-tetrahydro-pyran-3-ol analogues, and novel 3,6-disubstituted pyran derivatives |
US7531555B2 (en) | 2003-10-01 | 2009-05-12 | University Of Florida Research Foundation, Inc. | Compositions and methods for selective inhibition of nicotine acetylcholine receptors |
EP1734948B1 (en) | 2004-04-16 | 2014-06-11 | Wayne State University | Tri-substitued 2-benzhydryl-5-benzylamino-tetrahydro-pyran-4-ol and 6-benzhydryl-4-benzylamino-tetrahydro-pyran-3-ol analogues, and novel 3,6-disubstituted pyran derivatives |
DE602005019182D1 (en) | 2004-09-30 | 2010-03-18 | Ibiden Co Ltd | hONEYCOMB STRUCTURE |
JP5142532B2 (en) * | 2004-11-26 | 2013-02-13 | イビデン株式会社 | Honeycomb structure |
US20100048713A1 (en) * | 2006-01-06 | 2010-02-25 | Aarhus Universitet | Compounds acting on the serotonin transporter |
JP2009539806A (en) * | 2006-06-08 | 2009-11-19 | シュペーデル・エクスペリメンタ・アーゲー | 2,5-disubstituted piperidine |
WO2009073620A2 (en) * | 2007-11-30 | 2009-06-11 | Newlink Genetics | Ido inhibitors |
US8889730B2 (en) | 2012-04-10 | 2014-11-18 | Pfizer Inc. | Indole and indazole compounds that activate AMPK |
US9394285B2 (en) | 2013-03-15 | 2016-07-19 | Pfizer Inc. | Indole and indazole compounds that activate AMPK |
EP3233799B1 (en) * | 2014-12-19 | 2021-05-19 | The Broad Institute, Inc. | Dopamine d2 receptor ligands |
WO2016100940A1 (en) | 2014-12-19 | 2016-06-23 | The Broad Institute, Inc. | Dopamine d2 receptor ligands |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU598750B2 (en) | 1985-09-27 | 1990-07-05 | Mitsubishi Chemical Corporation | Phenylalanine derivative and proteinase inhibitor |
ES2086341T3 (en) | 1989-09-12 | 1996-07-01 | Hoechst Ag | DERIVATIVES OF AMINO ACIDS WITH RENINE INHIBITING PROPERTIES, PROCEDURE FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR USE. |
US5232929A (en) * | 1990-11-28 | 1993-08-03 | Pfizer Inc. | 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use |
GB9000301D0 (en) * | 1990-01-06 | 1990-03-07 | Pfizer Ltd | Piperidine & pyrrolidine derivatives |
US5300499A (en) * | 1992-09-02 | 1994-04-05 | Allergan, Inc. | 5-substituted 3-thiophene sulfonamides as antiglaucoma agents |
JPH09249566A (en) | 1996-03-19 | 1997-09-22 | Takeda Chem Ind Ltd | Piperidine-containing chemokine receptor antagonist |
US6369077B1 (en) | 1997-05-08 | 2002-04-09 | Smithkline Beecham Corporation | Protease inhibitors |
CN100418951C (en) * | 1997-11-18 | 2008-09-17 | 帝人医药株式会社 | Cycloamine derivative and its use as medicine |
ES2235883T3 (en) * | 1999-05-06 | 2005-07-16 | Neurogen Corporation | 4-OXO-QUINOLINO-3-SUBSTITUTED CARBOXAMIDS: GABA CEREBRAL RECEIVERS LIGANDOS. |
AU2001275537A1 (en) * | 2000-06-20 | 2002-01-02 | Wayne State University | N-and o-substituted 4-(2-(diphenylmethoxy)-ethyl)-1-((phenyl)methyl)piperidine analogs and methods of treating cns disorders therewith |
-
2001
- 2001-06-14 AU AU2001275537A patent/AU2001275537A1/en not_active Abandoned
- 2001-06-14 WO PCT/US2001/040964 patent/WO2001098266A2/en active Application Filing
- 2001-06-14 US US10/311,796 patent/US6995268B2/en not_active Expired - Fee Related
-
2004
- 2004-12-08 US US11/007,484 patent/US7595331B2/en not_active Expired - Fee Related
-
2009
- 2009-09-28 US US12/568,503 patent/US20100016600A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20030225133A1 (en) | 2003-12-04 |
WO2001098266A2 (en) | 2001-12-27 |
US7595331B2 (en) | 2009-09-29 |
US6995268B2 (en) | 2006-02-07 |
US20050154021A1 (en) | 2005-07-14 |
WO2001098266A3 (en) | 2002-04-04 |
US20100016600A1 (en) | 2010-01-21 |
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