AU2001273461A1 - Methods for recombinatorial nucleic acid synthesis - Google Patents
Methods for recombinatorial nucleic acid synthesisInfo
- Publication number
- AU2001273461A1 AU2001273461A1 AU2001273461A AU7346101A AU2001273461A1 AU 2001273461 A1 AU2001273461 A1 AU 2001273461A1 AU 2001273461 A AU2001273461 A AU 2001273461A AU 7346101 A AU7346101 A AU 7346101A AU 2001273461 A1 AU2001273461 A1 AU 2001273461A1
- Authority
- AU
- Australia
- Prior art keywords
- recombinatorial
- methods
- nucleic acid
- acid synthesis
- synthesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/613,535 US6994963B1 (en) | 2000-07-10 | 2000-07-10 | Methods for recombinatorial nucleic acid synthesis |
US09/613,535 | 2000-07-10 | ||
PCT/US2001/022195 WO2002004630A2 (en) | 2000-07-10 | 2001-07-10 | Methods for recombinatorial nucleic acid synthesis |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001273461A1 true AU2001273461A1 (en) | 2002-01-21 |
Family
ID=24457683
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001273461A Abandoned AU2001273461A1 (en) | 2000-07-10 | 2001-07-10 | Methods for recombinatorial nucleic acid synthesis |
Country Status (3)
Country | Link |
---|---|
US (1) | US6994963B1 (en) |
AU (1) | AU2001273461A1 (en) |
WO (1) | WO2002004630A2 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7332308B1 (en) * | 1999-05-21 | 2008-02-19 | The Penn State Research Foundation | Incrementally truncated nucleic acids and methods of making same |
US7871799B2 (en) * | 2002-11-22 | 2011-01-18 | Lawrence Livermore National Security, Llc | Sequential addition of short DNA oligos in DNA-polymerase-based synthesis reactions |
TWI333977B (en) * | 2003-09-18 | 2010-12-01 | Symphogen As | Method for linking sequences of interest |
US7501254B2 (en) * | 2006-07-20 | 2009-03-10 | Ghc Technologies, Inc. | Methods and compositions for amplification and capture of nucleic acid sequences |
JP5669397B2 (en) * | 2007-03-01 | 2015-02-12 | シムフォゲン・アクティーゼルスカブSymphogen A/S | Methods for cloning cognate antibodies |
CA2735020A1 (en) * | 2008-08-29 | 2010-03-04 | Symphogen A/S | Method for cloning avian-derived antibodies |
KR20170119729A (en) | 2009-02-13 | 2017-10-27 | 엑스-켐, 인크. | Methods of creating and screening dna-encoded libraries |
WO2013036810A1 (en) | 2011-09-07 | 2013-03-14 | X-Chem, Inc. | Methods for tagging dna-encoded libraries |
IL236633B (en) | 2012-07-13 | 2022-07-01 | X Chem Inc | Dna-encoded libraries comprising a complex having a cross-linking oligonucleotide linkage |
EP3673064A4 (en) | 2017-08-24 | 2021-05-26 | Takara Bio USA, Inc. | Methods of producing nucleic acids using oligonucleotides modified by a stimulus |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59161398A (en) * | 1983-03-02 | 1984-09-12 | Mitsui Toatsu Chem Inc | Method and apparatus for incising deoxyribonucleic acid |
EP0229046B1 (en) | 1985-03-30 | 1994-05-04 | BALLIVET, Marc | Method for obtaining dna, rna, peptides, polypeptides or proteins by means of a dna recombinant technique |
US4865968A (en) * | 1985-04-01 | 1989-09-12 | The Salk Institute For Biological Studies | DNA sequencing |
US5674679A (en) * | 1991-09-27 | 1997-10-07 | Amersham Life Science, Inc. | DNA cycle sequencing |
GB9208733D0 (en) * | 1992-04-22 | 1992-06-10 | Medical Res Council | Dna sequencing method |
DE69310179T2 (en) * | 1992-07-31 | 1997-07-31 | Behringwerke Ag | METHOD FOR INTRODUCING DEFINED SEQUENCES AT THE 3 'END OF POLYNUCLEOTIDES |
US6165793A (en) | 1996-03-25 | 2000-12-26 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
US6117679A (en) | 1994-02-17 | 2000-09-12 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
US6335160B1 (en) | 1995-02-17 | 2002-01-01 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
CN1123328A (en) * | 1994-11-17 | 1996-05-29 | 中国科学院上海生物化学研究所 | High-temp. and high-fidelity deoxyibonucleic acid (DNA) polymerase (HiFi Bst) |
US5830655A (en) * | 1995-05-22 | 1998-11-03 | Sri International | Oligonucleotide sizing using cleavable primers |
US5965408A (en) | 1996-07-09 | 1999-10-12 | Diversa Corporation | Method of DNA reassembly by interrupting synthesis |
JPH1066576A (en) | 1996-08-07 | 1998-03-10 | Novo Nordisk As | Double-stranded dna having protruding terminal and shuffling method using the same |
GB9701425D0 (en) | 1997-01-24 | 1997-03-12 | Bioinvent Int Ab | A method for in vitro molecular evolution of protein function |
EP0996718B1 (en) | 1997-03-18 | 2008-12-24 | Novozymes A/S | Method for constructing a library using dna shuffling |
US6159687A (en) | 1997-03-18 | 2000-12-12 | Novo Nordisk A/S | Methods for generating recombined polynucleotides |
CA2284097A1 (en) | 1997-03-18 | 1998-09-24 | Novo Nordisk A/S | Shuffling of heterologous dna sequences |
CA2284253A1 (en) | 1997-03-18 | 1998-09-24 | Jesper Vind | An in vitro method for construction of a dna library |
US6153410A (en) | 1997-03-25 | 2000-11-28 | California Institute Of Technology | Recombination of polynucleotide sequences using random or defined primers |
GB9712512D0 (en) | 1997-06-16 | 1997-08-20 | Bioinvent Int Ab | A method for in vitro molecular evolution of protein function |
DE19741714C2 (en) | 1997-09-22 | 2002-03-21 | Inst Molekulare Biotechnologie | Process for the synthesis and amplification of nucleic acids |
JP2001520043A (en) | 1997-10-17 | 2001-10-30 | ザ、プロクター、エンド、ギャンブル、カンパニー | Method for producing amylase enzyme |
AR017831A1 (en) | 1997-12-10 | 2001-10-24 | Pioneer Hi Bred Int | METHOD FOR ALTERING THE COMPOSITION OF AMINO ACIDS OF A NATIVE PROTEIN OF INTEREST, PREPARED PROTEIN, AND POLINUCLEOTIDE |
DE19812103A1 (en) | 1998-03-19 | 1999-09-23 | Bernauer Annette | Iteratively synthesizing nucleic acid from oligonucleotides which contain cleavable sites, useful for preparation of genes, ribozymes etc. |
FR2782323B1 (en) * | 1998-08-12 | 2002-01-11 | Proteus | PROCESS FOR THE IN VITRO PRODUCTION OF RECOMBINANT POLYNUCLEOTIDE SEQUENCES, SEQUENCE BANKS AND SEQUENCES THUS OBTAINED |
AU3210200A (en) | 1999-01-19 | 2000-08-01 | Maxygen, Inc. | Oligonucleotide mediated nucleic acid recombination |
US6534292B1 (en) * | 2000-05-08 | 2003-03-18 | Genencor International, Inc. | Methods for forming recombined nucleic acids |
-
2000
- 2000-07-10 US US09/613,535 patent/US6994963B1/en not_active Expired - Lifetime
-
2001
- 2001-07-10 AU AU2001273461A patent/AU2001273461A1/en not_active Abandoned
- 2001-07-10 WO PCT/US2001/022195 patent/WO2002004630A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2002004630A3 (en) | 2002-08-29 |
WO2002004630A2 (en) | 2002-01-17 |
US6994963B1 (en) | 2006-02-07 |
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