AU2001273063A1 - Stabilized interleukin 2 - Google Patents

Stabilized interleukin 2

Info

Publication number
AU2001273063A1
AU2001273063A1 AU2001273063A AU7306301A AU2001273063A1 AU 2001273063 A1 AU2001273063 A1 AU 2001273063A1 AU 2001273063 A AU2001273063 A AU 2001273063A AU 7306301 A AU7306301 A AU 7306301A AU 2001273063 A1 AU2001273063 A1 AU 2001273063A1
Authority
AU
Australia
Prior art keywords
interleukin
stabilized
stabilized interleukin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001273063A
Inventor
Rajiv Nayar
Michael A. Shearer
Wei Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24424265&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2001273063(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Publication of AU2001273063A1 publication Critical patent/AU2001273063A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AU2001273063A 2000-06-28 2001-06-27 Stabilized interleukin 2 Abandoned AU2001273063A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/605,577 2000-06-28
US09/605,577 US6689353B1 (en) 2000-06-28 2000-06-28 Stabilized interleukin 2
PCT/US2001/020675 WO2002000243A2 (en) 2000-06-28 2001-06-27 Stabilized interleukin 2

Publications (1)

Publication Number Publication Date
AU2001273063A1 true AU2001273063A1 (en) 2002-01-08

Family

ID=24424265

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001273063A Abandoned AU2001273063A1 (en) 2000-06-28 2001-06-27 Stabilized interleukin 2

Country Status (24)

Country Link
US (1) US6689353B1 (en)
EP (1) EP1370280B1 (en)
JP (3) JP5522878B2 (en)
KR (1) KR100799402B1 (en)
CN (1) CN1523997B (en)
AR (1) AR029139A1 (en)
AU (1) AU2001273063A1 (en)
BR (1) BR0112101B1 (en)
CA (1) CA2413334C (en)
CO (1) CO5290308A1 (en)
CU (1) CU23536A3 (en)
DE (1) DE60142412D1 (en)
DO (1) DOP2001000197A (en)
EC (1) ECSP014106A (en)
ES (1) ES2344729T3 (en)
HN (1) HN2001000139A (en)
IL (2) IL153587A0 (en)
MX (1) MXPA03000046A (en)
MY (1) MY128629A (en)
PE (1) PE20020127A1 (en)
SV (1) SV2002000512A (en)
TW (1) TWI235063B (en)
UY (1) UY26805A1 (en)
WO (1) WO2002000243A2 (en)

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EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
PE20080251A1 (en) 2006-05-04 2008-04-25 Boehringer Ingelheim Int USES OF DPP IV INHIBITORS
EA030606B1 (en) 2006-05-04 2018-08-31 Бёрингер Ингельхайм Интернациональ Гмбх Methods of preparing a medicament comprising polymorphs
WO2008150479A2 (en) * 2007-06-01 2008-12-11 Acologix, Inc. High temperature stable peptide formulation
PE20140960A1 (en) 2008-04-03 2014-08-15 Boehringer Ingelheim Int FORMULATIONS INVOLVING A DPP4 INHIBITOR
DE102008023820A1 (en) 2008-05-08 2009-11-12 Aicuris Gmbh & Co. Kg An agent for the treatment and / or prophylaxis of an autoimmune disease and for the production of regulatory T cells
BRPI0916997A2 (en) 2008-08-06 2020-12-15 Boehringer Ingelheim International Gmbh DPP-4 INHIBITOR AND ITS USE
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
WO2010043566A2 (en) 2008-10-17 2010-04-22 Sanofi-Aventis Deutschland Gmbh Combination of an insulin and a glp-1 agonist
CA2761675A1 (en) * 2009-05-11 2010-11-18 Biomatrica, Inc. Compositions and methods for biological sample storage
US9707176B2 (en) 2009-11-13 2017-07-18 Sanofi-Aventis Deutschland Gmbh Pharmaceutical composition comprising a GLP-1 agonist and methionine
ES2855146T3 (en) 2009-11-13 2021-09-23 Sanofi Aventis Deutschland Pharmaceutical composition comprising a GLP-1 agonist, an insulin and methionine
ES2760917T3 (en) 2009-11-27 2020-05-18 Boehringer Ingelheim Int Treatment of diabetic patients genotyped with DPP-IV inhibitors such as linagliptin
JP6034781B2 (en) 2010-05-05 2016-11-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Combination therapy
US9376709B2 (en) 2010-07-26 2016-06-28 Biomatrica, Inc. Compositions for stabilizing DNA and RNA in blood and other biological samples during shipping and storage at ambient temperatures
EP2598661B1 (en) 2010-07-26 2017-09-27 Biomatrica, INC. Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
PT2611458T (en) 2010-08-30 2016-12-16 Sanofi Aventis Deutschland Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2
PT2637694T (en) 2010-11-12 2021-05-05 Nektar Therapeutics Conjugates of an il-2 moiety and a polymer
US9034883B2 (en) 2010-11-15 2015-05-19 Boehringer Ingelheim International Gmbh Vasoprotective and cardioprotective antidiabetic therapy
WO2012075379A2 (en) * 2010-12-02 2012-06-07 Oncolytics Biotech Inc. Liquid viral formulations
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
PT2750699E (en) 2011-08-29 2015-11-03 Sanofi Aventis Deutschland Pharmaceutical combination for use in glycemic control in diabetes type 2 patients
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
EP3685839A1 (en) 2012-05-14 2020-07-29 Boehringer Ingelheim International GmbH Linagliptin for use in the treatment of albuminuria and kidney related diseases
US9725703B2 (en) 2012-12-20 2017-08-08 Biomatrica, Inc. Formulations and methods for stabilizing PCR reagents
CN103063829B (en) * 2012-12-21 2015-01-14 杭州茂天赛科技有限公司 Frozen stock solution
GB201403775D0 (en) 2014-03-04 2014-04-16 Kymab Ltd Antibodies, uses & methods
JP6661554B2 (en) 2014-06-10 2020-03-11 バイオマトリカ，インク． Platelet stabilization at ambient temperature
SG11201700629TA (en) 2014-08-11 2017-02-27 Delinia Inc Modified il-2 variants that selectively activate regulatory t cells for the treatment of autoimmune diseases
CN107206058A (en) 2014-12-12 2017-09-26 赛诺菲-安万特德国有限公司 Insulin glargine/lixisenatide fixed ratio preparaton
TWI748945B (en) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 Treatment type 2 diabetes mellitus patients
TW201705975A (en) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 Treatment of type 2 diabetes mellitus patients
SG11201804776SA (en) 2015-12-08 2018-07-30 Biomatrica Inc Reduction of erythrocyte sedimentation rate
US20170204154A1 (en) 2016-01-20 2017-07-20 Delinia, Inc. Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases
JP2019517542A (en) 2016-06-10 2019-06-24 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Combination of linagliptin and metformin
US9567399B1 (en) 2016-06-20 2017-02-14 Kymab Limited Antibodies and immunocytokines
WO2018083248A1 (en) 2016-11-03 2018-05-11 Kymab Limited Antibodies, combinations comprising antibodies, biomarkers, uses & methods
US11077172B2 (en) 2016-11-08 2021-08-03 Delinia, Inc. IL-2 variants for the treatment of psoriasis
CA3056630A1 (en) 2017-03-15 2018-09-20 Pandion Therapeutics, Inc. Targeted immunotolerance
CA3064435A1 (en) 2017-05-24 2018-11-29 Pandion Therapeutics, Inc. Targeted immunotolerance
US10174091B1 (en) 2017-12-06 2019-01-08 Pandion Therapeutics, Inc. IL-2 muteins
US10946068B2 (en) 2017-12-06 2021-03-16 Pandion Operations, Inc. IL-2 muteins and uses thereof
AU2019246389A1 (en) 2018-03-28 2020-08-27 Ascendis Pharma Oncology Division A/S IL-2 conjugates
BR112021023345A2 (en) 2019-05-20 2022-02-01 Pandion Operations Inc Targeted immunotolerance in madcam
CA3162705A1 (en) 2019-12-17 2021-06-24 Amgen Inc. Dual interleukin-2 /tnf receptor agonist for use in therapy
MX2022007754A (en) 2019-12-20 2022-07-19 Regeneron Pharma Novel il2 agonists and methods of use thereof.
US11633488B2 (en) 2020-01-10 2023-04-25 Bright Peak Therapeutics Ag Modified IL-2 polypeptides and uses thereof
KR102653906B1 (en) 2020-01-14 2024-04-03 신테카인, 인크. Biased IL2 mutein methods and compositions
EP4161956A1 (en) 2020-06-03 2023-04-12 Ascendis Pharma Oncology Division A/S Il-2 sequences and uses thereof
TWI815194B (en) 2020-10-22 2023-09-11 美商基利科學股份有限公司 INTERLEUKIN-2-Fc FUSION PROTEINS AND METHODS OF USE
JP2023549191A (en) * 2020-11-13 2023-11-22 江蘇恒瑞医薬股▲ふん▼有限公司 Pharmaceutical compositions containing human interleukin 2 variants or derivatives thereof and uses thereof

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EP0158487B1 (en) * 1984-04-09 1991-08-28 Takeda Chemical Industries, Ltd. Stable composition of interleukin-2
JPS60215631A (en) * 1984-04-09 1985-10-29 Takeda Chem Ind Ltd Interleukin-2 composition
JPH0645551B2 (en) * 1986-01-07 1994-06-15 塩野義製薬株式会社 Interleukin-2 composition
JPH0229016A (en) * 1989-06-09 1990-01-31 Alpine Electron Inc Equalizer
US5358708A (en) 1993-01-29 1994-10-25 Schering Corporation Stabilization of protein formulations
US5656730A (en) * 1995-04-07 1997-08-12 Enzon, Inc. Stabilized monomeric protein compositions
US6267958B1 (en) * 1995-07-27 2001-07-31 Genentech, Inc. Protein formulation
US5763401A (en) 1996-07-12 1998-06-09 Bayer Corporation Stabilized albumin-free recombinant factor VIII preparation having a low sugar content
US6509023B1 (en) * 1997-07-31 2003-01-21 Rhodia Chimie Cosmetic composition comprising a functionalized polyorganosiloxane
DZ2788A1 (en) * 1998-05-15 2003-12-01 Bayer Ag Selective IL-2 agonists and antagonists.
US6689353B1 (en) * 2000-06-28 2004-02-10 Bayer Pharmaceuticals Corporation Stabilized interleukin 2

Also Published As

Publication number Publication date
KR100799402B1 (en) 2008-01-30
JP2004532791A (en) 2004-10-28
CN1523997A (en) 2004-08-25
CA2413334C (en) 2011-03-08
SV2002000512A (en) 2002-07-03
MXPA03000046A (en) 2003-06-19
CU23536A3 (en) 2010-06-17
JP5989728B2 (en) 2016-09-07
EP1370280B1 (en) 2010-06-16
CO5290308A1 (en) 2003-06-27
PE20020127A1 (en) 2002-04-27
TWI235063B (en) 2005-07-01
MY128629A (en) 2007-02-28
HN2001000139A (en) 2003-12-11
JP5522878B2 (en) 2014-06-18
UY26805A1 (en) 2002-01-31
BR0112101A (en) 2004-07-06
IL153587A (en) 2007-12-03
JP2012211166A (en) 2012-11-01
EP1370280A2 (en) 2003-12-17
ES2344729T3 (en) 2010-09-06
ECSP014106A (en) 2002-02-25
WO2002000243A2 (en) 2002-01-03
KR20030016312A (en) 2003-02-26
WO2002000243A3 (en) 2003-10-02
DOP2001000197A (en) 2003-01-15
IL153587A0 (en) 2003-07-06
JP2015007114A (en) 2015-01-15
CN1523997B (en) 2010-09-01
AR029139A1 (en) 2003-06-04
BR0112101B1 (en) 2017-11-14
US6689353B1 (en) 2004-02-10
DE60142412D1 (en) 2010-07-29
CA2413334A1 (en) 2002-01-03

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