AU2001270593A1 - Pharmaceutical compositions containing tobramycin and xanthan gum - Google Patents

Pharmaceutical compositions containing tobramycin and xanthan gum

Info

Publication number
AU2001270593A1
AU2001270593A1 AU2001270593A AU7059301A AU2001270593A1 AU 2001270593 A1 AU2001270593 A1 AU 2001270593A1 AU 2001270593 A AU2001270593 A AU 2001270593A AU 7059301 A AU7059301 A AU 7059301A AU 2001270593 A1 AU2001270593 A1 AU 2001270593A1
Authority
AU
Australia
Prior art keywords
pharmaceutical compositions
compositions containing
xanthan gum
containing tobramycin
tobramycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001270593A
Inventor
Nuria Carreras Perdiguer
Gemma Torrella Cabello
Jose Alberto Vallet Mas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Alcon Universal Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Universal Ltd filed Critical Alcon Universal Ltd
Publication of AU2001270593A1 publication Critical patent/AU2001270593A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AU2001270593A 2000-07-28 2001-06-26 Pharmaceutical compositions containing tobramycin and xanthan gum Abandoned AU2001270593A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22166000P 2000-07-28 2000-07-28
US60221660 2000-07-28
PCT/EP2001/007267 WO2002009724A1 (en) 2000-07-28 2001-06-26 Pharmaceutical compositions containing tobramycin and xanthan gum

Publications (1)

Publication Number Publication Date
AU2001270593A1 true AU2001270593A1 (en) 2002-02-13

Family

ID=22828757

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001270593A Abandoned AU2001270593A1 (en) 2000-07-28 2001-06-26 Pharmaceutical compositions containing tobramycin and xanthan gum

Country Status (18)

Country Link
US (1) US6352978B1 (en)
EP (1) EP1305033B1 (en)
CN (1) CN1218689C (en)
AR (1) AR029965A1 (en)
AT (1) ATE279927T1 (en)
AU (1) AU2001270593A1 (en)
BR (1) BR0112787B1 (en)
CA (1) CA2414737C (en)
CO (1) CO5300418A1 (en)
DE (1) DE60106619T2 (en)
DK (1) DK1305033T3 (en)
ES (1) ES2225573T3 (en)
MX (1) MXPA03000813A (en)
PL (1) PL199321B1 (en)
PT (1) PT1305033E (en)
TW (1) TWI282278B (en)
WO (1) WO2002009724A1 (en)
ZA (1) ZA200300110B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101031310B (en) * 2004-09-28 2010-10-27 千寿制药株式会社 Ophthalmic composition containing xanthan gum and amino acid
US7795316B1 (en) 2007-12-19 2010-09-14 Alcon Research, Ltd. Topical ophthalmic compositions containing tobramycin and dexamethasone
TWI495469B (en) * 2008-06-09 2015-08-11 Alcon Res Ltd Improved pharmaceutical compositions containing a fluoroquinolone antibiotic drug
AU2010356098B2 (en) * 2010-06-23 2014-08-14 Alcon Research, Ltd. Topical ophthalmic suspensions containing tobramycin and dexamethasone
WO2012151474A2 (en) * 2011-05-04 2012-11-08 Trustees Of Boston University Proton-motive force stimulation to potentiate aminoglycoside antibiotics against persistent bacteria

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3700451A (en) 1970-04-06 1972-10-24 Itek Corp Gelable and gelled compositions
US3944427A (en) 1970-04-06 1976-03-16 Itek Corporation Gelable and gelled compositions
US3784712A (en) 1970-12-23 1974-01-08 Gen Foods Corp Gum gelling system xanthan-tara dessert gel
CA1070629A (en) 1975-11-10 1980-01-29 Allen I. Laskin Process for modifying biopolymers
US4135979A (en) 1976-08-24 1979-01-23 Merck & Co., Inc. Treatment of xanthan gum to improve clarity
US4136177A (en) 1977-01-31 1979-01-23 American Home Products Corp. Xanthan gum therapeutic compositions
US4136178A (en) 1977-01-31 1979-01-23 American Home Products Corp. Locust bean gum therapeutic compositions
US4136173A (en) 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
GB8318403D0 (en) 1983-07-07 1983-08-10 Sutherland I W Gel-forming polysaccharides
FR2551087B1 (en) 1983-08-30 1986-03-21 Rhone Poulenc Spec Chim PROCESS FOR TREATING POLYSACCHARIDE SOLUTION AND USE THEREOF
DE3335593A1 (en) 1983-09-30 1985-04-11 Diamalt AG, 8000 München GELLING AND THICKENING AGENT BASED ON CASSIA GALACTOMANNANS
US4717713A (en) 1983-10-31 1988-01-05 Research Corporation Controlled release liquid pharmaceutical
US4708861A (en) 1984-02-15 1987-11-24 The Liposome Company, Inc. Liposome-gel compositions
FR2588189B1 (en) 1985-10-03 1988-12-02 Merck Sharp & Dohme LIQUID-GEL PHASE TRANSITION PHARMACEUTICAL COMPOSITION
US4647470A (en) 1985-11-27 1987-03-03 Merck & Co., Inc. Low-acetyl gellan gum blends
FR2618333B1 (en) 1987-07-20 1990-07-13 Merck Sharp & Dohme PHARMACEUTICAL AND / OR COSMETIC COMPOSITION FOR TOPICAL USE CONTAINING RHAMSAM GUM
US5192535A (en) 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
US4814160A (en) 1988-03-01 1989-03-21 Colgate-Palmolive Company Non-bleeding striped dentifrice
US5446070A (en) 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5234957A (en) 1991-02-27 1993-08-10 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5149694A (en) 1988-03-09 1992-09-22 Alcon Laboratories, Inc. Combination of tobramycin and dexamethasone for topical ophthalmic use
DE3843416A1 (en) 1988-12-23 1990-06-28 Wolff Walsrode Ag XANTHAN WITH IMPROVED SOLUBILITY AND METHOD FOR PRODUCTION
CA2021414C (en) 1989-07-25 2004-09-28 Daniel H. Doherty Genetic control of acetylation and pyruvylation of xanthan gum
US5461081A (en) 1989-09-28 1995-10-24 Alcon Laboratories, Inc. Topical ophthalmic pharmaceutical vehicles
FR2653021A1 (en) 1989-10-17 1991-04-19 Merck Sharp & Dohme AQUEOUS LIQUID OPHTHALMIC COMPOSITION WITH LIQUID-GEL PHASE TRANSITION.
EP0495421B1 (en) 1991-01-15 1996-08-21 Alcon Laboratories, Inc. Use of carrageenans in topical ophthalmic compositions
US5212162A (en) 1991-03-27 1993-05-18 Alcon Laboratories, Inc. Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions
JP2536806B2 (en) * 1991-03-27 1996-09-25 アルコン ラボラトリーズ インコーポレイテッド Topical ophthalmic composition combining gelled polysaccharide and finely divided drug carrier
DE69224071T2 (en) 1991-09-17 1998-05-07 Alcon Lab Inc COMPOSITIONS CONTAINING CHINOLANE AND ANTIBIOTICS AND POLYSTYRENE SULFONATE
US5192802A (en) 1991-09-25 1993-03-09 Mcneil-Ppc, Inc. Bioadhesive pharmaceutical carrier
US5318780A (en) 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
US5473062A (en) 1992-10-29 1995-12-05 Takeda Chemical Industries, Ltd. Process for producing purified xanthan gum
JP3228315B2 (en) 1993-04-23 2001-11-12 信越化学工業株式会社 Method for reducing the viable count of xanthan gum
WO1995019166A1 (en) 1994-01-14 1995-07-20 Shahinian Lee Jr A method for sustained and extended corneal analgesia
US5422116A (en) 1994-02-18 1995-06-06 Ciba-Geigy Corporation Liquid ophthalmic sustained release delivery system
ES2171186T3 (en) 1994-04-08 2002-09-01 Atrix Lab Inc LIQUID DIFFUSION COMPOSITIONS.
US5523301A (en) 1994-08-05 1996-06-04 Merck & Co., Inc. Optic nerve health
EP0725628B1 (en) 1994-08-30 2001-11-07 Alcon Laboratories, Inc. Thermally-gelling drug delivery vehicles containing cellulose ethers
US5972326A (en) 1995-04-18 1999-10-26 Galin; Miles A. Controlled release of pharmaceuticals in the anterior chamber of the eye
FR2742336B1 (en) 1995-12-19 1998-03-06 Chauvin Lab Sa EYE DROPS INTENDED IN PARTICULAR FOR TREATING EYE DRY
SE9603480L (en) 1996-09-23 1998-03-24 Johan Carlfors Dosage form for hard soluble drugs
FR2754712B1 (en) 1996-10-17 1999-09-03 Merck Sharp Dohme Chibret Lab OPHTHALMIC COMPOSITIONS
US5888493A (en) 1996-12-05 1999-03-30 Sawaya; Assad S. Ophthalmic aqueous gel formulation and related methods
WO1998053809A1 (en) 1997-05-30 1998-12-03 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension
KR20010013377A (en) * 1997-06-04 2001-02-26 데이비드 엠 모이어 Mild, leave-on antimicrobial compositions
JP2002506461A (en) 1997-06-26 2002-02-26 メルク エンド カンパニー インコーポレーテッド How to optimize retinal and optic nerve health
US6174524B1 (en) * 1999-03-26 2001-01-16 Alcon Laboratories, Inc. Gelling ophthalmic compositions containing xanthan gum
CN1133466C (en) * 1998-04-07 2004-01-07 阿尔康实验室公司 Gelling ophthalmic composition containing xanthan gum
US6297337B1 (en) * 1999-05-19 2001-10-02 Pmd Holdings Corp. Bioadhesive polymer compositions

Also Published As

Publication number Publication date
CO5300418A1 (en) 2003-07-31
CA2414737A1 (en) 2002-02-07
EP1305033B1 (en) 2004-10-20
DE60106619D1 (en) 2004-11-25
DK1305033T3 (en) 2005-01-31
CN1444482A (en) 2003-09-24
CA2414737C (en) 2009-01-06
MXPA03000813A (en) 2005-08-16
PL199321B1 (en) 2008-09-30
PL365154A1 (en) 2004-12-27
CN1218689C (en) 2005-09-14
BR0112787A (en) 2003-09-09
PT1305033E (en) 2005-01-31
US6352978B1 (en) 2002-03-05
BR0112787B1 (en) 2013-03-05
DE60106619T2 (en) 2005-03-17
ATE279927T1 (en) 2004-11-15
ES2225573T3 (en) 2005-03-16
US20020035088A1 (en) 2002-03-21
AR029965A1 (en) 2003-07-23
TWI282278B (en) 2007-06-11
WO2002009724A1 (en) 2002-02-07
EP1305033A1 (en) 2003-05-02
ZA200300110B (en) 2004-01-21

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