AU2001265154A1 - Method and composition for targeting an adenoviral vector - Google Patents
Method and composition for targeting an adenoviral vectorInfo
- Publication number
- AU2001265154A1 AU2001265154A1 AU2001265154A AU6515401A AU2001265154A1 AU 2001265154 A1 AU2001265154 A1 AU 2001265154A1 AU 2001265154 A AU2001265154 A AU 2001265154A AU 6515401 A AU6515401 A AU 6515401A AU 2001265154 A1 AU2001265154 A1 AU 2001265154A1
- Authority
- AU
- Australia
- Prior art keywords
- targeting
- composition
- adenoviral vector
- adenoviral
- vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10345—Special targeting system for viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/40—Vectors comprising a peptide as targeting moiety, e.g. a synthetic peptide, from undefined source
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/40—Vectors comprising a peptide as targeting moiety, e.g. a synthetic peptide, from undefined source
- C12N2810/405—Vectors comprising RGD peptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20845100P | 2000-05-31 | 2000-05-31 | |
US60/208,451 | 2000-05-31 | ||
US63119100A | 2000-08-02 | 2000-08-02 | |
US09/631,191 | 2000-08-02 | ||
PCT/US2001/017391 WO2001092549A2 (en) | 2000-05-31 | 2001-05-30 | Method and composition for targeting an adenoviral vector |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001265154A1 true AU2001265154A1 (en) | 2001-12-11 |
Family
ID=26903207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001265154A Abandoned AU2001265154A1 (en) | 2000-05-31 | 2001-05-30 | Method and composition for targeting an adenoviral vector |
Country Status (5)
Country | Link |
---|---|
US (1) | US20030099619A1 (en) |
EP (1) | EP1301612A2 (en) |
JP (1) | JP2003534806A (en) |
AU (1) | AU2001265154A1 (en) |
WO (1) | WO2001092549A2 (en) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
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US8071740B2 (en) * | 2000-11-17 | 2011-12-06 | Vascular Biogenics Ltd. | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis |
GB0112652D0 (en) * | 2001-05-24 | 2001-07-18 | Inst Of Molecul & Cell Biology | Internalisation of virus into cells |
JP5213298B2 (en) | 2002-05-27 | 2013-06-19 | ホルム,ペル・ゾンネ | New use of adenovirus and nucleic acid encoding it |
AU2003240281A1 (en) | 2002-06-14 | 2003-12-31 | Case Western Reserve University | Cell targeting methods and compositions |
DE602004032330D1 (en) * | 2003-02-17 | 2011-06-01 | Fuso Pharmaceutical Ind | NOVEL VIRUS VECTOR |
US20040166091A1 (en) | 2003-02-24 | 2004-08-26 | Genvec, Inc. | Materials and methods for treating disorders of the ear |
WO2004084950A2 (en) * | 2003-03-24 | 2004-10-07 | Case Western Reserve University | Cell targeting methods and compositions |
EP1613661B1 (en) * | 2003-04-04 | 2011-06-29 | Université de Lausanne | Peptabody for cancer treatment |
EP1649028B1 (en) * | 2003-07-25 | 2012-08-22 | Genvec, Inc. | Adenoviral vector-based vaccines |
FR2860004A1 (en) * | 2003-09-18 | 2005-03-25 | Roussy Inst Gustave | Adenoviral vector encoding modified capsid protein, useful in gene therapy of e.g. cancer and cystic fibrosis, can infect cells deficient in, or lacking, the common receptor for Coxsackie virus B3 and adenovirus |
JP2007511211A (en) | 2003-11-14 | 2007-05-10 | ホルム,ペル・ゾンネ | New use of adenovirus and nucleic acid encoding it |
EP1687032B1 (en) | 2003-11-14 | 2010-02-24 | Genvec, Inc. | Pharmaceutical composition for treating unresectable, locally advanced pancreatic cancer (lapc). |
CN1972958B (en) | 2004-04-12 | 2013-01-23 | 美国政府卫生与公共服务部 | Method of using adenoviral vectors to induce an immune response |
CN104263703B9 (en) * | 2004-05-26 | 2019-12-17 | 普西奥克瑟斯医疗有限公司 | Chimeric adenoviruses for the treatment of cancer |
US7776322B2 (en) * | 2004-08-16 | 2010-08-17 | Stefan Kochanek | Modified viral vector particles |
JP2008511336A (en) * | 2004-09-01 | 2008-04-17 | アメリカ合衆国 | Methods for using adenoviral vectors with increased immunogenicity in vivo |
US7556808B2 (en) | 2004-12-16 | 2009-07-07 | Philadelphia Health And Education Corporation | Dual inhibitors of HIV-1 gp-120 interactions |
EP1929021A2 (en) | 2005-08-31 | 2008-06-11 | Genvec, Inc. | Adenoviral vector-based malaria vaccines |
CA2629163C (en) | 2005-11-10 | 2017-03-21 | Genvec, Inc. | Adenoviral vector-based foot-and-mouth disease vaccine |
WO2007094653A1 (en) * | 2006-02-13 | 2007-08-23 | Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patientenzorg | Adenovirus particles having a chimeric adenovirus spike protein, use thereof and methods for producing such particles. |
CN101583580B (en) * | 2006-06-29 | 2012-10-31 | 高晓莲 | Make and use of surface molecules of varied densities |
WO2008140602A2 (en) * | 2006-12-07 | 2008-11-20 | The Govenment Of The Usa As Represented By The Secretary Of The Dept. Of Health And Human Services | USE OF ANTAGONISTS OF THE INTERACTION BETWEEN HIV GP120 AND α4β7 INTEGRIN |
WO2008086386A2 (en) * | 2007-01-09 | 2008-07-17 | Genvec, Inc. | Adenoviral vector-based malaria vaccines |
WO2009086516A1 (en) * | 2007-12-28 | 2009-07-09 | Kalos Therapeutics, Inc. | Anti-proliferative compounds and their use |
GB0803076D0 (en) * | 2008-02-20 | 2008-03-26 | Univ Ghent | Mucosal Membrane Receptor and uses thereof |
KR101154374B1 (en) * | 2009-02-18 | 2012-07-09 | 재단법인 아산사회복지재단 | Composition Comprising Adeno-Associated Virus Serotype 5 Vector for Targeted Gene Delivery |
WO2011047316A1 (en) | 2009-10-16 | 2011-04-21 | The United States Of America, As Represented By The Secretary Department Of Health And Human Services | Nucleic acid sequences encoding expandable hiv mosaic proteins |
WO2011057254A2 (en) | 2009-11-09 | 2011-05-12 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Simian adenoviral vector-based vaccines |
KR20120139672A (en) | 2009-11-09 | 2012-12-27 | 젠벡, 인코포레이티드 | Methods of propagating monkey adenoviral vectors |
WO2012021730A2 (en) | 2010-08-11 | 2012-02-16 | Genvec, Inc. | Respiratory syncytial virus (rsv) vaccine |
WO2012083297A2 (en) | 2010-12-17 | 2012-06-21 | Genvec, Inc. | Adenoviral vectors with modified hexon regions |
WO2012088041A1 (en) | 2010-12-20 | 2012-06-28 | Genvec, Inc. | Adenoviral vector-based dengue fever vaccine |
EP2855669B1 (en) | 2012-05-29 | 2018-10-10 | GenVec, Inc. | Modified serotype 28 adenoviral vectors |
JP6576326B2 (en) | 2013-03-14 | 2019-09-18 | ソーク インスティテュート フォー バイオロジカル スタディーズ | Oncolytic adenovirus composition |
HUE035875T2 (en) | 2013-10-25 | 2018-06-28 | Psioxus Therapeutics Ltd | Oncolytic adenoviruses armed with heterologous genes |
TWI710635B (en) | 2014-10-09 | 2020-11-21 | 美商珍維克公司 | Adenoviral vector encoding human atonal homolog-1 (hath1) |
CN107690479B (en) | 2015-04-30 | 2022-02-18 | 皮斯奥克斯治疗公司 | Oncolytic adenovirus encoding B7 protein |
MX2018007249A (en) | 2015-12-17 | 2019-05-16 | Psioxus Therapeutics Ltd | Group b adenovirus encoding an anti-tcr-complex antibody or fragment. |
KR20180112024A (en) | 2016-02-23 | 2018-10-11 | 더 솔크 인스티튜트 포 바이올로지칼 스터디즈 | Exogenous gene expression of therapeutic adenoviruses for minimizing the effects on viral dynamics |
AU2017222568B2 (en) | 2016-02-23 | 2020-09-10 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
CA3018427A1 (en) * | 2016-03-31 | 2017-10-05 | The European Molecular Biology Laboratory | Adenoviral coat protein derived delivery vehicles |
GB201713765D0 (en) | 2017-08-28 | 2017-10-11 | Psioxus Therapeutics Ltd | Modified adenovirus |
WO2018064523A1 (en) | 2016-09-30 | 2018-04-05 | Genvec, Inc. | Adenovectors for delivery of therapeutic genetic material into t cells |
JP2019536468A (en) | 2016-12-12 | 2019-12-19 | ソーク インスティテュート フォー バイオロジカル スタディーズ | Synthetic adenovirus targeting tumors and uses thereof |
US20210139932A1 (en) * | 2017-05-03 | 2021-05-13 | Biomarin Pharmaceutical Inc. | Improved lentiviruses for transduction of hematopoietic stem cells |
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US4593002A (en) * | 1982-01-11 | 1986-06-03 | Salk Institute Biotechnology/Industrial Associates, Inc. | Viruses with recombinant surface proteins |
US4792525A (en) * | 1982-08-04 | 1988-12-20 | La Jolla Cancer Research Foundation | Tetrapeptide |
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US5166320A (en) * | 1987-04-22 | 1992-11-24 | University Of Connecticut | Carrier system and method for the introduction of genes into mammalian cells |
US5663143A (en) * | 1988-09-02 | 1997-09-02 | Dyax Corp. | Engineered human-derived kunitz domains that inhibit human neutrophil elastase |
US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
NZ244306A (en) * | 1991-09-30 | 1995-07-26 | Boehringer Ingelheim Int | Composition for introducing nucleic acid complexes into eucaryotic cells, complex containing nucleic acid and endosomolytic agent, peptide with endosomolytic domain and nucleic acid binding domain and preparation |
US5981273A (en) * | 1991-09-30 | 1999-11-09 | Boehringer Ingelheim Int'l. Gmbh | Composition comprising an endosomolytic agent for introducing nucleic acid complexes into higher eucaryotic cells |
US5521291A (en) * | 1991-09-30 | 1996-05-28 | Boehringer Ingelheim International, Gmbh | Conjugates for introducing nucleic acid into higher eucaryotic cells |
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SE503225C2 (en) * | 1991-10-30 | 1996-04-22 | Leif Lindholm Konsult Ab | Virus-antibody complex for introduction of virus into mammalian cells |
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US5981505A (en) * | 1993-01-26 | 1999-11-09 | The Trustees Of The University Of Pennsylvania | Compositions and methods for delivery of genetic material |
DE4311651A1 (en) * | 1993-04-08 | 1994-10-13 | Boehringer Ingelheim Int | Virus for the transport of foreign DNA into higher eukaryotic cells |
US5543328A (en) * | 1993-08-13 | 1996-08-06 | Genetic Therapy, Inc. | Adenoviruses having modified fiber proteins |
US5443953A (en) * | 1993-12-08 | 1995-08-22 | Immunomedics, Inc. | Preparation and use of immunoconjugates |
US5783386A (en) * | 1994-02-24 | 1998-07-21 | Agresearch, New Zealand Pastoral Agriculture Research Institute Ltd. | Mycobacteria virulence factors and a novel method for their identification |
US5559099A (en) * | 1994-09-08 | 1996-09-24 | Genvec, Inc. | Penton base protein and methods of using same |
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US5958672A (en) * | 1995-07-18 | 1999-09-28 | Diversa Corporation | Protein activity screening of clones having DNA from uncultivated microorganisms |
AUPN477695A0 (en) * | 1995-08-14 | 1995-09-07 | Commonwealth Scientific And Industrial Research Organisation | Gene therapy |
US5622699A (en) * | 1995-09-11 | 1997-04-22 | La Jolla Cancer Research Foundation | Method of identifying molecules that home to a selected organ in vivo |
US5939250A (en) * | 1995-12-07 | 1999-08-17 | Diversa Corporation | Production of enzymes having desired activities by mutagenesis |
AU726544B2 (en) * | 1995-12-08 | 2000-11-09 | University Of Alabama At Birmingham Research Foundation, The | Targeted adenovirus vectors |
US5955275A (en) * | 1997-02-14 | 1999-09-21 | Arcaris, Inc. | Methods for identifying nucleic acid sequences encoding agents that affect cellular phenotypes |
US5922315A (en) * | 1997-01-24 | 1999-07-13 | Genetic Therapy, Inc. | Adenoviruses having altered hexon proteins |
EP0974668B1 (en) * | 1998-07-07 | 2002-10-02 | Transgene S.A. | Use of adenoviral E4 reading frames to improve expression of a gene of interest |
-
2001
- 2001-05-30 JP JP2002500741A patent/JP2003534806A/en active Pending
- 2001-05-30 AU AU2001265154A patent/AU2001265154A1/en not_active Abandoned
- 2001-05-30 WO PCT/US2001/017391 patent/WO2001092549A2/en not_active Application Discontinuation
- 2001-05-30 EP EP01939660A patent/EP1301612A2/en not_active Withdrawn
-
2002
- 2002-11-25 US US10/304,160 patent/US20030099619A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2003534806A (en) | 2003-11-25 |
EP1301612A2 (en) | 2003-04-16 |
US20030099619A1 (en) | 2003-05-29 |
WO2001092549A3 (en) | 2003-01-16 |
WO2001092549A2 (en) | 2001-12-06 |
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