AU2001261741A1 - Diagnosis, prevention and treatment of crohn's disease using the ompc antigen - Google Patents
Diagnosis, prevention and treatment of crohn's disease using the ompc antigenInfo
- Publication number
- AU2001261741A1 AU2001261741A1 AU2001261741A AU6174101A AU2001261741A1 AU 2001261741 A1 AU2001261741 A1 AU 2001261741A1 AU 2001261741 A AU2001261741 A AU 2001261741A AU 6174101 A AU6174101 A AU 6174101A AU 2001261741 A1 AU2001261741 A1 AU 2001261741A1
- Authority
- AU
- Australia
- Prior art keywords
- disease
- crohn
- diagnosis
- prevention
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/24—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- G01N2333/245—Escherichia (G)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
- G01N2333/39—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts
- G01N2333/395—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts from Saccharomyces
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/848—Escherichia
- Y10S435/849—Escherichia coli
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/965—Chemistry: molecular biology and microbiology involving idiotype or anti-idiotype antibody
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/973—Simultaneous determination of more than one analyte
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
Abstract
The present invention provides a method of diagnosing Crohn's disease in a subject by determining the presence or absence or IgA anti-OmpC antibodies in the subject, where the presence of the IgA anti-OmpC antibodies indicates that the subject has Crohn's disease.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/575,061 US7138237B1 (en) | 2000-05-19 | 2000-05-19 | Diagnosis, prevention and treatment of Crohn's disease using the OmpC antigen |
US09575061 | 2000-05-19 | ||
PCT/US2001/016032 WO2001089361A2 (en) | 2000-05-19 | 2001-05-17 | Diagnosis, prevention and treatment of crohn's disease using the ompc antigen |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001261741A1 true AU2001261741A1 (en) | 2001-12-03 |
Family
ID=24298769
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001261741A Abandoned AU2001261741A1 (en) | 2000-05-19 | 2001-05-17 | Diagnosis, prevention and treatment of crohn's disease using the ompc antigen |
Country Status (8)
Country | Link |
---|---|
US (4) | US7138237B1 (en) |
EP (1) | EP1285271B1 (en) |
JP (1) | JP4917728B2 (en) |
AT (1) | ATE302411T1 (en) |
AU (1) | AU2001261741A1 (en) |
DE (1) | DE60112744T2 (en) |
ES (1) | ES2247115T3 (en) |
WO (1) | WO2001089361A2 (en) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7138237B1 (en) * | 2000-05-19 | 2006-11-21 | Cedars-Sinai Medical Center | Diagnosis, prevention and treatment of Crohn's disease using the OmpC antigen |
DK1581119T3 (en) | 2001-12-17 | 2013-05-13 | Corixa Corp | Compositions and Methods for Therapy and Diagnosis of Inflammatory Bowel Diseases |
US20040053263A1 (en) * | 2002-08-30 | 2004-03-18 | Abreu Maria T. | Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease |
US20040076960A1 (en) * | 2002-10-18 | 2004-04-22 | Taylor Kent D. | Methods of using a NOD2/CARD15 haplotype to diagnose Crohn's disease |
US7018188B2 (en) | 2003-04-08 | 2006-03-28 | The Procter & Gamble Company | Apparatus for forming fibers |
WO2004091372A2 (en) * | 2003-04-11 | 2004-10-28 | Cedars-Sinai Medical Center | Methods of assessing crohn’s disease patient phenotype by i2, ompc and asca serologic response |
US7662569B2 (en) * | 2003-04-11 | 2010-02-16 | Cedars-Sinai Medical Center | Methods of assessing Crohn's disease patient phenotype by I2 serologic response |
US7759079B2 (en) * | 2004-05-13 | 2010-07-20 | Prometheus Laboratories Inc. | Methods of diagnosing inflammatory bowel disease |
US20060154276A1 (en) | 2004-05-13 | 2006-07-13 | Prometheus Laboratories Inc. | Methods of diagnosing inflammatory bowel disease |
FR2876798A1 (en) * | 2004-10-14 | 2006-04-21 | Univ Clermont Auvergne | DIAGNOSIS AND TREATMENT OF CROHN'S DISEASE |
US10544459B2 (en) | 2004-12-08 | 2020-01-28 | Cedars-Sinai Medical Center | Methods of using genetic variants for the diagnosis and treatment of inflammatory bowel disease |
US11268149B2 (en) | 2004-12-08 | 2022-03-08 | Cedars-Sinai Medical Center | Diagnosis and treatment of inflammatory bowel disease |
EP2270512B1 (en) * | 2004-12-08 | 2016-03-23 | Cedars-Sinai Medical Center | Methods for diagnosis of Crohn's disease |
JP4577083B2 (en) * | 2005-04-28 | 2010-11-10 | 味の素株式会社 | How to diagnose Crohn's disease |
US7873479B2 (en) | 2005-12-01 | 2011-01-18 | Prometheus Laboratories Inc. | Methods of diagnosing inflammatory bowel disease |
US7943328B1 (en) | 2006-03-03 | 2011-05-17 | Prometheus Laboratories Inc. | Method and system for assisting in diagnosing irritable bowel syndrome |
US20070282714A1 (en) * | 2006-04-27 | 2007-12-06 | Snocap, Inc. | System, method and computer program product for providing an e-commerce interface on a web page to facilitate e-commerce involving digital assets |
US20080085524A1 (en) * | 2006-08-15 | 2008-04-10 | Prometheus Laboratories Inc. | Methods for diagnosing irritable bowel syndrome |
US20100094560A1 (en) * | 2006-08-15 | 2010-04-15 | Prometheus Laboratories Inc. | Methods for diagnosing irritable bowel syndrome |
US8685741B1 (en) | 2007-03-07 | 2014-04-01 | Nestec S.A. | Methods for diagnosing irritable bowel syndrome |
WO2008116150A2 (en) | 2007-03-21 | 2008-09-25 | Cedars-Sinai Medical Center | Ileal pouch-anal anastomosis (ipaa) factors in the treatment of inflammatory bowel disease |
EP2359137A4 (en) | 2008-11-11 | 2012-05-30 | Prometheus Lab Inc | Methods for prediction of inflammatory bowel disease (ibd) using serologic markers |
WO2010062960A2 (en) | 2008-11-26 | 2010-06-03 | Cedars-Sinai Medical Center | METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE |
US9580752B2 (en) | 2008-12-24 | 2017-02-28 | Cedars-Sinai Medical Center | Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy |
JP5660027B2 (en) * | 2009-03-05 | 2015-01-28 | 味の素株式会社 | Crohn's disease diagnostic reagent |
ES2553415T3 (en) | 2009-04-14 | 2015-12-09 | Nestec S.A. | Prognosis method of inflammatory bowel disease |
JP5736370B2 (en) | 2009-06-25 | 2015-06-17 | ネステク ソシエテ アノニム | Diagnosis of irritable bowel syndrome |
MX339330B (en) | 2009-08-14 | 2016-05-20 | Procter & Gamble | Spinning die assembly and method for forming fibres using said assembly. |
WO2011060098A1 (en) | 2009-11-10 | 2011-05-19 | Prometheus Laboratories Inc. | Methods for predicting post-surgery risk associated with ileal pouch-anal anastomosis |
US8445215B1 (en) | 2010-07-23 | 2013-05-21 | Nestec S.A. | Assays and methods for the detection of Crohn's disease |
CN103502815B (en) | 2011-02-17 | 2015-09-23 | 雀巢产品技术援助有限公司 | Detect the determination method for the autoantibody of anti-TNF alpha medicine |
WO2015067913A1 (en) | 2013-11-07 | 2015-05-14 | Diagnodus Limited | Biomarkers |
BR112013028808A2 (en) | 2011-05-10 | 2016-09-06 | Nestec Sa | Disease Activity Profile Characterization Methods for Personalized Therapy Management |
EP2710383B1 (en) | 2011-05-16 | 2017-01-11 | The University of Newcastle | Performance of a biomarker panel for irritable bowel syndrome |
MX352274B (en) | 2011-10-21 | 2017-11-16 | Nestec Sa | Methods for improving inflammatory bowel disease diagnosis. |
MX358730B (en) | 2012-10-05 | 2018-09-03 | Nestec Sa | Methods for predicting and monitoring mucosal healing. |
KR20210157418A (en) | 2013-03-27 | 2021-12-28 | 세다르스-신나이 메디칼 센터 | Mitigation and reversal of fibrosis and inflammation by inhibition of tl1a function and related signaling pathways |
EP3022295A4 (en) | 2013-07-19 | 2017-03-01 | Cedars-Sinai Medical Center | Signature of tl1a (tnfsf15) signaling pathway |
WO2015083087A1 (en) | 2013-12-03 | 2015-06-11 | Nestec S.A. | Methods for predicting post-operative recurrence of crohn's disease |
AU2016349703A1 (en) * | 2015-11-06 | 2018-11-01 | Vetica Labs, Inc. | Methods of detecting inflammatory markers and treating inflammatory conditions in companion animals |
US11186872B2 (en) | 2016-03-17 | 2021-11-30 | Cedars-Sinai Medical Center | Methods of diagnosing inflammatory bowel disease through RNASET2 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4444879A (en) * | 1981-01-29 | 1984-04-24 | Science Research Center, Inc. | Immunoassay with article having support film and immunological counterpart of analyte |
US5681699A (en) | 1994-02-11 | 1997-10-28 | Cedars-Sinai Medical Center | Methods of diagnosing ulcerative colitis and Crohn's disease |
US5691151A (en) * | 1994-10-07 | 1997-11-25 | Regents Of University Of California | Methods of screening for ulcerative colitis and crohn's disease by detecting VH3-15 autoantibody and panca |
US6033864A (en) | 1996-04-12 | 2000-03-07 | The Regents Of The University Of California | Diagnosis, prevention and treatment of ulcerative colitis, and clinical subtypes thereof, using microbial UC pANCA antigens |
US5874233A (en) | 1996-04-12 | 1999-02-23 | Cedars-Sinai Medical Center | Methods of diagnosing a clinical subtype of Crohn's disease with features of ulcerative colitis |
US5932429A (en) * | 1996-04-12 | 1999-08-03 | Cedars-Sinai Medical Center | Methods of diagnosing clinical subtypes of crohn's disease |
US5916748A (en) | 1996-04-12 | 1999-06-29 | Cedars-Sinai Medical Center | Method of diagnosing a clinical subtype of crohn's disease with features of ulcerative colitis |
US5968741A (en) * | 1997-04-11 | 1999-10-19 | Cedars-Sinai Medical Center | Methods of diagnosing a medically resistant clinical subtype of ulcerative colitis |
GB9806449D0 (en) * | 1998-03-25 | 1998-05-27 | Peptide Therapeutics Ltd | Attenuated bacteria useful in vaccines |
US6218129B1 (en) * | 1998-05-15 | 2001-04-17 | Prometheus Laboratories, Inc. | Inflammatory bowel disease first step assay system |
US7138237B1 (en) * | 2000-05-19 | 2006-11-21 | Cedars-Sinai Medical Center | Diagnosis, prevention and treatment of Crohn's disease using the OmpC antigen |
-
2000
- 2000-05-19 US US09/575,061 patent/US7138237B1/en not_active Expired - Lifetime
-
2001
- 2001-05-17 AT AT01935666T patent/ATE302411T1/en not_active IP Right Cessation
- 2001-05-17 WO PCT/US2001/016032 patent/WO2001089361A2/en active IP Right Grant
- 2001-05-17 ES ES01935666T patent/ES2247115T3/en not_active Expired - Lifetime
- 2001-05-17 EP EP01935666A patent/EP1285271B1/en not_active Expired - Lifetime
- 2001-05-17 AU AU2001261741A patent/AU2001261741A1/en not_active Abandoned
- 2001-05-17 DE DE60112744T patent/DE60112744T2/en not_active Expired - Lifetime
- 2001-05-17 JP JP2001585609A patent/JP4917728B2/en not_active Expired - Fee Related
-
2006
- 2006-11-17 US US11/561,024 patent/US7993865B2/en not_active Expired - Fee Related
-
2009
- 2009-01-12 US US12/352,578 patent/US7993866B2/en not_active Expired - Fee Related
- 2009-01-12 US US12/352,579 patent/US7993867B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1285271B1 (en) | 2005-08-17 |
EP1285271A2 (en) | 2003-02-26 |
US20090221007A1 (en) | 2009-09-03 |
US7138237B1 (en) | 2006-11-21 |
JP4917728B2 (en) | 2012-04-18 |
WO2001089361A2 (en) | 2001-11-29 |
US20070161065A1 (en) | 2007-07-12 |
EP1285271A4 (en) | 2003-07-23 |
ES2247115T3 (en) | 2006-03-01 |
US7993865B2 (en) | 2011-08-09 |
DE60112744T2 (en) | 2006-06-14 |
ATE302411T1 (en) | 2005-09-15 |
WO2001089361A3 (en) | 2002-03-28 |
DE60112744D1 (en) | 2005-09-22 |
US7993866B2 (en) | 2011-08-09 |
US7993867B2 (en) | 2011-08-09 |
JP2004526122A (en) | 2004-08-26 |
US20090221006A1 (en) | 2009-09-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2001261741A1 (en) | Diagnosis, prevention and treatment of crohn's disease using the ompc antigen | |
WO2003039462A3 (en) | B-cell lymphoma specific antigen for use in diagnosis and treatment of b-cell malignancies | |
WO2003016467A3 (en) | Use of antibodies having high affinity for soluble ass to treat conditions and diseases related to ass | |
WO2001014424A3 (en) | Human ctla-4 antibodies and their uses | |
HK1015413A1 (en) | Monkey monoclonal antibodies specific to human b7.1 and/or b7.2 primatized forms, pharaceutical compositions | |
WO2003011899A3 (en) | Antigenic polypeptides | |
WO2002058717A3 (en) | Methods for treating rheumatoid arthritis using il-17 antagonists | |
WO2001058485A3 (en) | Prophylactic and therapeutic antibodies against vaccina virus antigens | |
WO2002075274A3 (en) | Method and kit for following neurodegenerative diseases | |
WO2003075855A3 (en) | Antibodies against cancer antigen tmeff2 and uses thereof | |
AU7260496A (en) | A method and diagnostic test kit for use in aiding the diagnosis of fibromyyalgia and chronic fatigue syndrome (CFS) | |
WO2000033872A3 (en) | Method of and compositions for immunization with the pseudomonas v antigen | |
WO2004069873A3 (en) | Antigen/antibody or ligand/receptor glycosylated specificity exchangers | |
WO2002064161A3 (en) | Method and compositions for immunization with the pseudomonas v antigen | |
EP1354896A4 (en) | Novel monoclonal antibody | |
AU4396401A (en) | Composition and method for the prevention and/or the treatment of allergy | |
MX237690B (en) | System and method of verifying the authenticity of dynamically connectable executable images. | |
WO2003083083A3 (en) | Methods of using flt3-ligand in immunization protocols | |
EP1028754A4 (en) | Prevention of immunoreactivity by depleting or inhibiting antigen presenting cells | |
ITRM940297A0 (en) | "DEVICE FOR THE TRANSMISSION OF MANUAL ACCELERATION, BRAKING AND SIMILAR COMMANDS". | |
WO2001068134A3 (en) | Therapies that improve graft survival, using antibodies against a b7 antigen | |
WO1998051782A3 (en) | Human 3-hydroxyisobutyryl-coenzyme a hydrolase | |
AU7128098A (en) | Methods of obtaining antigens specific for fungi, antibodies for such antigens, and diagnosis of disease using such antigens and/or antibodies | |
AU3637195A (en) | Broadly reactive opsonic antibodies reactive with common staphylococcal antigens | |
NZ514691A (en) | Method to type prion proteins |