AU2001259174A1 - Viral and non-viral vectors as vehicles for delivering transgenes for treating bone pathologies - Google Patents
Viral and non-viral vectors as vehicles for delivering transgenes for treating bone pathologiesInfo
- Publication number
- AU2001259174A1 AU2001259174A1 AU2001259174A AU5917401A AU2001259174A1 AU 2001259174 A1 AU2001259174 A1 AU 2001259174A1 AU 2001259174 A AU2001259174 A AU 2001259174A AU 5917401 A AU5917401 A AU 5917401A AU 2001259174 A1 AU2001259174 A1 AU 2001259174A1
- Authority
- AU
- Australia
- Prior art keywords
- viral
- vehicles
- treating bone
- bone pathologies
- viral vectors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 108700019146 Transgenes Proteins 0.000 title 1
- 210000000988 bone and bone Anatomy 0.000 title 1
- 230000007170 pathology Effects 0.000 title 1
- 239000013603 viral vector Substances 0.000 title 1
- 230000003612 virological effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/561,524 US7105494B1 (en) | 1997-10-29 | 2000-04-28 | Viral and non-viral vectors as vehicles for delivering transgenes for treating bone pathologies |
US09/561,524 | 2000-04-28 | ||
PCT/US2001/013493 WO2001082973A2 (en) | 2000-04-28 | 2001-04-27 | Viral and non-viral vectors as vehicles for delivering transgenes for treating bone pathologies |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001259174A1 true AU2001259174A1 (en) | 2001-11-12 |
Family
ID=24242327
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001259174A Abandoned AU2001259174A1 (en) | 2000-04-28 | 2001-04-27 | Viral and non-viral vectors as vehicles for delivering transgenes for treating bone pathologies |
Country Status (3)
Country | Link |
---|---|
US (3) | US20060099182A1 (en) |
AU (1) | AU2001259174A1 (en) |
WO (1) | WO2001082973A2 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006050211A2 (en) * | 2004-10-28 | 2006-05-11 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Peripherally delivered glutamic acid decarboxylase gene therapy for spinal cord injury pain |
WO2006132388A1 (en) | 2005-06-06 | 2006-12-14 | Waseda University | Bone marrow-directing drug delivery materials and their applications |
US20100233137A1 (en) * | 2007-02-27 | 2010-09-16 | Lanx, Inc. | Compositions and Methods for Modification of Target Cells and to Their Uses Thereof |
US20100150881A1 (en) * | 2007-06-01 | 2010-06-17 | Lanx, Inc. | Compositions and Methods for Use of Scar Tissue in Repair of Weight Bearing Surfaces |
WO2009105606A1 (en) * | 2008-02-21 | 2009-08-27 | Lanx, Llc | Compositions and methods for use of scar tissue in repair of weight bearing surfaces |
US9149319B2 (en) * | 2008-09-23 | 2015-10-06 | Lanx, Llc | Methods and compositions for stabilization of a vertebra |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5032407A (en) * | 1987-01-16 | 1991-07-16 | Ohio University Edison Animal Biotechnology Center | Gene transfer using transformed, neodetermined, embryonic cells |
JP3015383B2 (en) * | 1987-09-11 | 2000-03-06 | ホワイトヘツド・インスチチユート・フオー・バイオメデイカル・リサーチ | Transduced fibroblasts and their use |
US5670488A (en) * | 1992-12-03 | 1997-09-23 | Genzyme Corporation | Adenovirus vector for gene therapy |
US5618531A (en) * | 1990-10-19 | 1997-04-08 | New York University | Method for increasing the viability of cells which are administered to the brain or spinal cord |
US5858355A (en) * | 1990-12-20 | 1999-01-12 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | IRAP gene as treatment for arthritis |
US5674844A (en) * | 1991-03-11 | 1997-10-07 | Creative Biomolecules, Inc. | Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases |
US5837258A (en) * | 1991-08-30 | 1998-11-17 | University Of South Florida | Induction of tissue, bone or cartilage formation using connective tissue growth factor |
US5789543A (en) * | 1993-12-30 | 1998-08-04 | President And Fellows Of Harvard College | Vertebrate embryonic pattern-inducing proteins and uses related thereto |
US5763416A (en) * | 1994-02-18 | 1998-06-09 | The Regent Of The University Of Michigan | Gene transfer into bone cells and tissues |
US5962427A (en) * | 1994-02-18 | 1999-10-05 | The Regent Of The University Of Michigan | In vivo gene transfer methods for wound healing |
US5942496A (en) * | 1994-02-18 | 1999-08-24 | The Regent Of The University Of Michigan | Methods and compositions for multiple gene transfer into bone cells |
US5665350A (en) * | 1994-11-23 | 1997-09-09 | University Of Massachusetts Medical Center | Cell cycle dependent transplantation and ex vivo gene therapy |
US5719131A (en) * | 1994-12-09 | 1998-02-17 | Genzyme Corporation | Cationic amphiphiles containing dialkylamine lipophilic groups for intracellular delivery of therapeutic molecules |
US5948767A (en) * | 1994-12-09 | 1999-09-07 | Genzyme Corporation | Cationic amphiphile/DNA complexes |
US5650096A (en) * | 1994-12-09 | 1997-07-22 | Genzyme Corporation | Cationic amphiphiles for intracellular delivery of therapeutic molecules |
US5767099A (en) * | 1994-12-09 | 1998-06-16 | Genzyme Corporation | Cationic amphiphiles containing amino acid or dervatized amino acid groups for intracellular delivery of therapeutic molecules |
US5910487A (en) * | 1994-12-09 | 1999-06-08 | Genzyme Corporation | Cationic amphiphiles and plasmids for intracellular delivery of therapeutic molecules |
US5824655A (en) * | 1995-02-15 | 1998-10-20 | The University Of Utah | Anti-transforming growth factor-β gene therapy |
WO1998042270A1 (en) * | 1997-03-25 | 1998-10-01 | Morris Laster | Bone marrow as a site for transplantation |
US5912239A (en) * | 1997-04-04 | 1999-06-15 | Genzyme Corporation | Imidazole-containing cationic amphiphiles for intracellular delivery of therapeutic molecules |
ATE388720T1 (en) * | 1997-04-10 | 2008-03-15 | Univ Southern California | MODIFIED PROTEINS BONDING TO EXTRACELLULAR MATRIX COMPONENTS |
US5981275A (en) * | 1997-04-14 | 1999-11-09 | Genzyme Corporation | Transgene expression system for increased persistence |
US5948925A (en) * | 1997-05-06 | 1999-09-07 | Genzyme Corporation | Cationic amphiphiles containing linkers derived from neutral or positively charged amino acids |
US5952516A (en) * | 1997-05-08 | 1999-09-14 | Genzyme Corporation | Cationic amphiphiles containing multiplesteroid lipophilic groups |
US6077987A (en) * | 1997-09-04 | 2000-06-20 | North Shore-Long Island Jewish Research Institute | Genetic engineering of cells to enhance healing and tissue regeneration |
CA2308511C (en) * | 1997-10-29 | 2016-01-19 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Use of transfected or transduced mammalian cells for treating bone pathologies |
AU3189899A (en) * | 1998-03-18 | 1999-10-11 | University Of Virginia Patent Foundation | Gene therapy vector with osteocalcin promoter and genes for bone morphogenic proteins or growth factors |
AU6519299A (en) * | 1998-10-15 | 2000-05-01 | General Hospital Corporation, The | Bone morphogenic protein-induced genes and polypeptides, and their use in diagnostic and therapeutic methods |
WO2001013960A1 (en) * | 1999-08-20 | 2001-03-01 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Methods for in vivo gene delivery to sites of cartilage damage |
WO2005018549A2 (en) * | 2003-08-12 | 2005-03-03 | The Brigham And Women' S Hospital, Inc. | Methods and compositions for tissue repair |
-
2001
- 2001-04-27 WO PCT/US2001/013493 patent/WO2001082973A2/en active Application Filing
- 2001-04-27 AU AU2001259174A patent/AU2001259174A1/en not_active Abandoned
-
2005
- 2005-12-14 US US11/300,698 patent/US20060099182A1/en not_active Abandoned
-
2011
- 2011-06-14 US US13/160,403 patent/US20110280935A1/en not_active Abandoned
-
2012
- 2012-08-15 US US13/586,685 patent/US20120309817A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2001082973A2 (en) | 2001-11-08 |
US20110280935A1 (en) | 2011-11-17 |
WO2001082973A3 (en) | 2003-02-06 |
US20060099182A1 (en) | 2006-05-11 |
US20120309817A1 (en) | 2012-12-06 |
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