AU2001255734A1 - Sigma-2 receptors as biomarkers of tumor cell proliferation - Google Patents

Sigma-2 receptors as biomarkers of tumor cell proliferation

Info

Publication number
AU2001255734A1
AU2001255734A1 AU2001255734A AU5573401A AU2001255734A1 AU 2001255734 A1 AU2001255734 A1 AU 2001255734A1 AU 2001255734 A AU2001255734 A AU 2001255734A AU 5573401 A AU5573401 A AU 5573401A AU 2001255734 A1 AU2001255734 A1 AU 2001255734A1
Authority
AU
Australia
Prior art keywords
sigma
biomarkers
receptors
cell proliferation
tumor cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001255734A
Inventor
Robert H. Mach
Kenneth T. Wheeler Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wake Forest University
Original Assignee
Wake Forest University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wake Forest University filed Critical Wake Forest University
Publication of AU2001255734A1 publication Critical patent/AU2001255734A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
    • C07F13/005—Compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof

Abstract

The present invention provides novel sigma-2 ligands (labeled and unlabeled) and the use of the compounds in medical therapy or diagnosis.
AU2001255734A 2000-04-27 2001-04-27 Sigma-2 receptors as biomarkers of tumor cell proliferation Abandoned AU2001255734A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20005200P 2000-04-27 2000-04-27
US60200052 2000-04-27
PCT/US2001/013583 WO2001080905A2 (en) 2000-04-27 2001-04-27 Sigma-2 receptors as biomarkers of tumor cell proliferation

Publications (1)

Publication Number Publication Date
AU2001255734A1 true AU2001255734A1 (en) 2001-11-07

Family

ID=22740117

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001255734A Abandoned AU2001255734A1 (en) 2000-04-27 2001-04-27 Sigma-2 receptors as biomarkers of tumor cell proliferation

Country Status (7)

Country Link
US (1) US6669925B1 (en)
EP (1) EP1278745B1 (en)
AT (1) ATE256682T1 (en)
AU (1) AU2001255734A1 (en)
CA (1) CA2407520C (en)
DE (1) DE60101570T2 (en)
WO (1) WO2001080905A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008512360A (en) * 2004-09-07 2008-04-24 トライアンフ，オペレーティング アズ ア ジョイント ヴェンチャー バイ ザ ガバナーズ オブ ザ ユニバーシティ オブ アルバータ，ザ ユニバーシティ オブ ブリティッシュ コロンビア，カールトン Method for synthesizing sugar-metal complexes labeled with radioisotopes
EP4153209A1 (en) 2020-05-20 2023-03-29 The Board of Trustees of the University of Illinois Method for treating lysosomal storage diseases with histatin peptides

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0235878A3 (en) 1986-01-16 1989-06-14 Beecham Group Plc Novel compounds
DE3785507T2 (en) 1986-07-31 1993-07-29 Beecham Group Plc AZABICYCLIC COMPOUNDS, METHOD FOR THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE.
US5223511A (en) * 1987-09-23 1993-06-29 Boehringer Ingelheim Italia S.P.A. Benzimidazoline-2-oxo-1-carboxylic acid compounds useful as 5-HT receptor antagonists
AU611976B2 (en) 1987-12-24 1991-06-27 John Wyeth & Brother Limited Aroyl urea and carbamic acid derivatives of azabicyclo compounds
DK443489D0 (en) 1989-09-08 1989-09-08 Ferrosan As SUBSTITUTED URINARY COMPOUNDS, THEIR PREPARATION AND USE
GB9121835D0 (en) 1991-10-15 1991-11-27 Smithkline Beecham Plc Pharmaceuticals
KR970701174A (en) 1994-02-10 1997-03-17 오노다 마사요시 Novel carbamate derivative and medicinal composition containing the same
JP2000506896A (en) * 1996-03-20 2000-06-06 ウェイク フォレスト ユニバーシティ Sigma-2 receptor as a biomarker of tumor cell proliferation

Also Published As

Publication number Publication date
DE60101570T2 (en) 2004-09-30
EP1278745A2 (en) 2003-01-29
EP1278745B1 (en) 2003-12-17
WO2001080905A3 (en) 2002-05-30
US6669925B1 (en) 2003-12-30
DE60101570D1 (en) 2004-01-29
CA2407520A1 (en) 2001-11-01
ATE256682T1 (en) 2004-01-15
WO2001080905A2 (en) 2001-11-01
CA2407520C (en) 2010-02-02

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