AU2001255044A1 - Electrically-mediated transdermal drug injection - Google Patents

Electrically-mediated transdermal drug injection

Info

Publication number
AU2001255044A1
AU2001255044A1 AU2001255044A AU5504401A AU2001255044A1 AU 2001255044 A1 AU2001255044 A1 AU 2001255044A1 AU 2001255044 A AU2001255044 A AU 2001255044A AU 5504401 A AU5504401 A AU 5504401A AU 2001255044 A1 AU2001255044 A1 AU 2001255044A1
Authority
AU
Australia
Prior art keywords
electrically
transdermal drug
drug injection
substance
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001255044A
Inventor
Zohar Avrahami
Yosef Gross
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TransPharma Ltd
Original Assignee
TransPharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TransPharma Ltd filed Critical TransPharma Ltd
Publication of AU2001255044A1 publication Critical patent/AU2001255044A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2046—Media being expelled from injector by gas generation, e.g. explosive charge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Electrotherapy Devices (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Apparatus (20) for injection of a substance (28) through the stratum corneum of skin (26) is provided. The apparatus includes a reservoir (42), containing the substance. The reservoir preferably has at least one outlet. A pressure generator (22) applies a pressure to eject the substance through the at least one outlet. One or more electrodes (32, 34) in a vicinity of the outlet are placed on the skin. Energy is conveyed through the electrodes to the skin, to facilitate passage of the substance through the stratum corneum.
AU2001255044A 2000-05-07 2001-05-03 Electrically-mediated transdermal drug injection Abandoned AU2001255044A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL136008 2000-05-07
IL13600800A IL136008A0 (en) 2000-05-07 2000-05-07 Electrically-mediated transdermal drug injection
PCT/IL2001/000397 WO2001085234A2 (en) 2000-05-07 2001-05-03 Electrically-mediated transdermal drug injection

Publications (1)

Publication Number Publication Date
AU2001255044A1 true AU2001255044A1 (en) 2001-11-20

Family

ID=11074106

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001255044A Abandoned AU2001255044A1 (en) 2000-05-07 2001-05-03 Electrically-mediated transdermal drug injection

Country Status (7)

Country Link
US (1) US20030173110A1 (en)
EP (1) EP1289581B1 (en)
AT (1) ATE333294T1 (en)
AU (1) AU2001255044A1 (en)
DE (1) DE60121583T2 (en)
IL (1) IL136008A0 (en)
WO (1) WO2001085234A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003089043A2 (en) * 2002-04-19 2003-10-30 Transpharma Medical Ltd. Handheld transdermal drug delivery and analyte extraction
IL152573A (en) 2002-10-31 2009-11-18 Transpharma Medical Ltd Transdermal delivery system for anti-emetic medication
IL152575A (en) 2002-10-31 2008-12-29 Transpharma Medical Ltd Transdermal delivery system for water insoluble drugs
WO2005096979A1 (en) 2004-04-01 2005-10-20 The General Hospital Corporation Method and apparatus for dermatological treatment and tissue reshaping
US8357150B2 (en) 2009-07-20 2013-01-22 Syneron Medical Ltd. Method and apparatus for fractional skin treatment
JP6297794B2 (en) * 2013-06-12 2018-03-20 株式会社ダイセル Syringe
EP3397144A4 (en) * 2015-12-28 2019-02-13 Inovio Pharmaceuticals, Inc. Intradermal jet injection electroporation device
US10413671B2 (en) * 2017-09-12 2019-09-17 Portal Instruments, Inc. Rotary motor based transdermal injection device

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5117235A (en) * 1974-08-04 1976-02-12 Senichi Masuda Seidenfuntaitochakusochi
US4775361A (en) * 1986-04-10 1988-10-04 The General Hospital Corporation Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport
ATE131081T1 (en) * 1988-01-21 1995-12-15 Massachusetts Inst Technology MOLECULAR TRANSPORT THROUGH TISSUES USING ELECTROPORATION.
US5423803A (en) * 1991-10-29 1995-06-13 Thermotrex Corporation Skin surface peeling process using laser
US6210402B1 (en) * 1995-11-22 2001-04-03 Arthrocare Corporation Methods for electrosurgical dermatological treatment
US5165418B1 (en) 1992-03-02 1999-12-14 Nikola I Tankovich Blood sampling device and method using a laser
US5304128A (en) 1992-09-22 1994-04-19 Habley Medical Technology Corporation Gas powered self contained syringe
ATE212526T1 (en) * 1993-12-07 2002-02-15 Svedman Paul TRANSDERMAL SAMPLE COLLECTION DEVICE
US5983131A (en) * 1995-08-11 1999-11-09 Massachusetts Institute Of Technology Apparatus and method for electroporation of tissue
IL123379A (en) 1995-08-29 2002-04-21 Spectrx Inc Microporation of human skin for drug delivery and monitoring applications
US5860957A (en) * 1997-02-07 1999-01-19 Sarcos, Inc. Multipathway electronically-controlled drug delivery system
US6148232A (en) * 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US5983135A (en) * 1998-12-24 1999-11-09 Avrahami; Zohar Transdermal delivery of fine powders
US6328033B1 (en) * 1999-06-04 2001-12-11 Zohar Avrahami Powder inhaler
US6520936B1 (en) * 1999-06-08 2003-02-18 Medtronic Minimed, Inc. Method and apparatus for infusing liquids using a chemical reaction in an implanted infusion device
US7133717B2 (en) * 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling

Also Published As

Publication number Publication date
ATE333294T1 (en) 2006-08-15
IL136008A0 (en) 2001-05-20
EP1289581A2 (en) 2003-03-12
DE60121583D1 (en) 2006-08-31
WO2001085234A3 (en) 2002-03-28
EP1289581B1 (en) 2006-07-19
DE60121583T2 (en) 2006-11-16
US20030173110A1 (en) 2003-09-18
WO2001085234A2 (en) 2001-11-15

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