AU2001253246A1 - Inhibitors of prenyl-protein transferase - Google Patents

Inhibitors of prenyl-protein transferase

Info

Publication number
AU2001253246A1
AU2001253246A1 AU2001253246A AU5324601A AU2001253246A1 AU 2001253246 A1 AU2001253246 A1 AU 2001253246A1 AU 2001253246 A AU2001253246 A AU 2001253246A AU 5324601 A AU5324601 A AU 5324601A AU 2001253246 A1 AU2001253246 A1 AU 2001253246A1
Authority
AU
Australia
Prior art keywords
prenyl
inhibitors
protein transferase
transferase
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001253246A
Inventor
Diem N. Nguyen
Craig A. Stump
Theresa M. Williams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU2001253246A1 publication Critical patent/AU2001253246A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001253246A 2000-04-10 2001-04-06 Inhibitors of prenyl-protein transferase Abandoned AU2001253246A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19595100P 2000-04-10 2000-04-10
US60195951 2000-04-10
PCT/US2001/011397 WO2001077116A1 (en) 2000-04-10 2001-04-06 Inhibitors of prenyl-protein transferase

Publications (1)

Publication Number Publication Date
AU2001253246A1 true AU2001253246A1 (en) 2001-10-23

Family

ID=22723496

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001253246A Abandoned AU2001253246A1 (en) 2000-04-10 2001-04-06 Inhibitors of prenyl-protein transferase

Country Status (3)

Country Link
US (1) US6534506B2 (en)
AU (1) AU2001253246A1 (en)
WO (1) WO2001077116A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2338789T3 (en) 2003-06-18 2010-05-12 Tranzyme Pharma Inc. MACROCICLIC ANTAGONISTS OF THE MOTILINA RECEPTOR.
EP2285970A4 (en) * 2008-06-03 2011-10-12 Aileron Therapeutics Inc Compositions and methods for enhancing cellular transport of biomolecules

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995000497A1 (en) 1993-06-18 1995-01-05 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
WO1995008542A1 (en) 1993-09-22 1995-03-30 Kyowa Hakko Kogyo Co., Ltd. Farnesyltransferase inhibitor
JPH09504277A (en) * 1993-09-30 1997-04-28 メルク エンド カンパニー インコーポレーテッド Farnesyl-protein transferase inhibitors
US5856326A (en) 1995-03-29 1999-01-05 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5756528A (en) 1995-06-06 1998-05-26 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5919785A (en) 1996-04-03 1999-07-06 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5885995A (en) 1996-04-03 1999-03-23 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
WO1997036592A1 (en) 1996-04-03 1997-10-09 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5859012A (en) 1996-04-03 1999-01-12 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
EP1014984A1 (en) 1997-08-27 2000-07-05 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
WO1999020609A1 (en) 1997-10-17 1999-04-29 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
EP1091736A4 (en) 1998-07-02 2001-10-24 Merck & Co Inc Inhibitors of prenyl-protein transferase
US6410534B1 (en) 1998-07-02 2002-06-25 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
WO2000001702A1 (en) 1998-07-02 2000-01-13 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
US6329376B1 (en) * 1998-10-29 2001-12-11 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
WO2001051128A1 (en) * 2000-01-12 2001-07-19 Merck & Co., Inc. Inhibitors of prenyl-protein transferase

Also Published As

Publication number Publication date
US6534506B2 (en) 2003-03-18
WO2001077116A1 (en) 2001-10-18
US20020123497A1 (en) 2002-09-05

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