AU2001248414A1 - Multiblock micro-arrays or macro-arrays with lab-on-a-chip - Google Patents

Multiblock micro-arrays or macro-arrays with lab-on-a-chip

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Publication number
AU2001248414A1
AU2001248414A1 AU2001248414A AU4841401A AU2001248414A1 AU 2001248414 A1 AU2001248414 A1 AU 2001248414A1 AU 2001248414 A AU2001248414 A AU 2001248414A AU 4841401 A AU4841401 A AU 4841401A AU 2001248414 A1 AU2001248414 A1 AU 2001248414A1
Authority
AU
Australia
Prior art keywords
arrays
multiblock
lab
macro
micro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001248414A
Inventor
Francois Geli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU2001248414A1 publication Critical patent/AU2001248414A1/en
Abandoned legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01L3/502707Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
AU2001248414A 2000-03-22 2001-03-22 Multiblock micro-arrays or macro-arrays with lab-on-a-chip Abandoned AU2001248414A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0003680 2000-03-22
FR0003680A FR2806646A1 (en) 2000-03-22 2000-03-22 MULTIBLOCK MICRO-ARRAYS OR MACRO-ARRAYS WITH LABORATORIES ON INTEGRATED CHIPS
PCT/FR2001/000881 WO2001070400A1 (en) 2000-03-22 2001-03-22 Multiblock micro-arrays or macro-arrays with lab-on-a-chip

Publications (1)

Publication Number Publication Date
AU2001248414A1 true AU2001248414A1 (en) 2001-10-03

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Application Number Title Priority Date Filing Date
AU2001248414A Abandoned AU2001248414A1 (en) 2000-03-22 2001-03-22 Multiblock micro-arrays or macro-arrays with lab-on-a-chip

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AU (1) AU2001248414A1 (en)
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Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7201873B2 (en) 2001-04-16 2007-04-10 Tosoh Corporation Fine channel device, method for producing the fine channel device and use of the same
US6622746B2 (en) 2001-12-12 2003-09-23 Eastman Kodak Company Microfluidic system for controlled fluid mixing and delivery
US6568799B1 (en) 2002-01-23 2003-05-27 Eastman Kodak Company Drop-on-demand ink jet printer with controlled fluid flow to effect drop ejection
ES2190897B1 (en) * 2002-02-04 2005-02-01 Universidad De Sevilla MATTERS OF CHEMICAL AND BIOLOGICAL UTILITY BEHAVIORS.
ATE358533T1 (en) 2002-08-02 2007-04-15 Ge Healthcare Sv Corp INTEGRATED MICROCHIP DESIGN
EP1560642A4 (en) 2002-10-09 2006-05-03 Univ Illinois Microfluidic systems and components
US7011793B2 (en) 2003-05-15 2006-03-14 Kionix, Inc. Reconfigurable modular microfluidic system and method of fabrication
DE10345028B4 (en) * 2003-09-25 2009-09-10 Microfluidic Chipshop Gmbh Device for holding and connecting microfluidic systems
EP1799348A2 (en) * 2004-08-04 2007-06-27 Spinx, Inc. Devices and methods for interfacing microfluidic devices with fluid handling devices
US8383060B2 (en) 2006-03-20 2013-02-26 Koninklijke Philips Electronics N.V. System-in-package platform for electronic-microfluidic devices
US7932034B2 (en) 2006-12-20 2011-04-26 The Board Of Trustees Of The Leland Stanford Junior University Heat and pH measurement for sequencing of DNA
US8303909B2 (en) 2009-11-30 2012-11-06 Corning Incorporated Microfluidic assembly
EP2752237B1 (en) * 2011-07-25 2016-03-16 Csir Array printing
US9029297B2 (en) 2011-07-25 2015-05-12 Csir Array printing
US9012375B2 (en) 2011-07-25 2015-04-21 Csir Array printing
US9951349B2 (en) 2011-09-27 2018-04-24 Yale University Compositions and methods for transient expression of recombinant RNA
DE102012010959B4 (en) 2012-05-30 2019-03-28 Technische Universität Dresden Apparatus for providing constant flow ratios of different fluid phases in microchannel elements
US9700891B2 (en) 2015-11-13 2017-07-11 International Business Machines Corporation Integrated nanofluidic arrays for high capacity colloid separation
AR114207A1 (en) 2018-01-15 2020-08-05 Baker Hughes A Ge Co Llc USE OF MICROFLUIDS AS A RAPID EVALUATION TECHNOLOGY FOR ENHANCED OIL RECOVERY

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3915652A (en) * 1973-08-16 1975-10-28 Samuel Natelson Means for transferring a liquid in a capillary open at both ends to an analyzing system
US5508200A (en) * 1992-10-19 1996-04-16 Tiffany; Thomas Method and apparatus for conducting multiple chemical assays
US5872010A (en) * 1995-07-21 1999-02-16 Northeastern University Microscale fluid handling system
DE69835342T2 (en) * 1998-04-27 2007-08-23 Corning Inc. Method for storing biological samples with the aid of a redrawn capillary store
DE19846466A1 (en) * 1998-10-08 2000-04-27 Ghs Gesundheits Service Ag Analysis method for the simultaneous determination of parameters from different media

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