AU2001246657A1 - Use of analogues of superoxide dismutase for treating hepatocellular insufficiencies - Google Patents
Use of analogues of superoxide dismutase for treating hepatocellular insufficienciesInfo
- Publication number
- AU2001246657A1 AU2001246657A1 AU2001246657A AU4665701A AU2001246657A1 AU 2001246657 A1 AU2001246657 A1 AU 2001246657A1 AU 2001246657 A AU2001246657 A AU 2001246657A AU 4665701 A AU4665701 A AU 4665701A AU 2001246657 A1 AU2001246657 A1 AU 2001246657A1
- Authority
- AU
- Australia
- Prior art keywords
- insufficiencies
- superoxide dismutase
- analogues
- treating hepatocellular
- hepatocellular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical class [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 title abstract 2
- 102000019197 Superoxide Dismutase Human genes 0.000 title abstract 2
- 108010012715 Superoxide dismutase Proteins 0.000 title abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000009109 curative therapy Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
- A61K38/446—Superoxide dismutase (1.15)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
- C12Y111/01—Peroxidases (1.11.1)
- C12Y111/01006—Catalase (1.11.1.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
- C12Y111/01—Peroxidases (1.11.1)
- C12Y111/01009—Glutathione peroxidase (1.11.1.9)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y115/00—Oxidoreductases acting on superoxide as acceptor (1.15)
- C12Y115/01—Oxidoreductases acting on superoxide as acceptor (1.15) with NAD or NADP as acceptor (1.15.1)
- C12Y115/01001—Superoxide dismutase (1.15.1.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Abstract
The invention concerns the use of a compound having a superoxide dismustase activity, in particular a non-peptide analogue of the superoxide dismutase to obtain a medicine for preventive or curative treatment of hepatocellular insufficiency. Said medicine can be used in particular for treating hepatocellular insufficiencies of toxic or viral origin.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0003887A FR2806911B1 (en) | 2000-03-28 | 2000-03-28 | USE OF SOD MIMETICS IN THE TREATMENT OF HEPATOCELLULAR DEFICIENCIES |
FR0003887 | 2000-03-28 | ||
PCT/FR2001/000939 WO2001072327A2 (en) | 2000-03-28 | 2001-03-28 | Use of analogues of superoxide dismutase for treating hepatocellular insufficiencies |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001246657A1 true AU2001246657A1 (en) | 2001-10-08 |
Family
ID=8848555
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001246657A Abandoned AU2001246657A1 (en) | 2000-03-28 | 2001-03-28 | Use of analogues of superoxide dismutase for treating hepatocellular insufficiencies |
Country Status (9)
Country | Link |
---|---|
US (1) | US20030118577A1 (en) |
EP (1) | EP1267881B1 (en) |
JP (1) | JP2003528152A (en) |
AT (1) | ATE303151T1 (en) |
AU (1) | AU2001246657A1 (en) |
CA (1) | CA2404077A1 (en) |
DE (1) | DE60113078T2 (en) |
FR (1) | FR2806911B1 (en) |
WO (1) | WO2001072327A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7299082B2 (en) | 2003-10-31 | 2007-11-20 | Abbott Diabetes Care, Inc. | Method of calibrating an analyte-measurement device, and associated methods, devices and systems |
US7699964B2 (en) | 2004-02-09 | 2010-04-20 | Abbott Diabetes Care Inc. | Membrane suitable for use in an analyte sensor, analyte sensor, and associated method |
US8165651B2 (en) * | 2004-02-09 | 2012-04-24 | Abbott Diabetes Care Inc. | Analyte sensor, and associated system and method employing a catalytic agent |
US7885698B2 (en) | 2006-02-28 | 2011-02-08 | Abbott Diabetes Care Inc. | Method and system for providing continuous calibration of implantable analyte sensors |
KR20110065549A (en) * | 2008-10-03 | 2011-06-15 | 샬롯테-맥클렌버그 하스피털 오쏘러티 두잉 비지니스 에즈 카롤리나스 메디컬 센터 | Treatment of hepatitis c infection with metalloporphyrins |
AU2014374361B9 (en) | 2013-12-31 | 2019-07-04 | Abbott Diabetes Care Inc. | Self-powered analyte sensor and devices using the same |
CN113693189B (en) * | 2021-09-28 | 2023-11-17 | 中国农业科学院北京畜牧兽医研究所 | Application and method of manganese peroxidase for degrading patulin |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0653670B2 (en) * | 1985-10-28 | 1994-07-20 | 日研フ−ド株式会社 | Side effect reducing agent for chemotherapeutic agents |
EP0282899B1 (en) * | 1987-03-14 | 1996-01-10 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Human manganese superoxide dismutase (hMn-SoD) |
JPS6490133A (en) * | 1987-09-29 | 1989-04-06 | Otsuka Pharma Co Ltd | Pharmaceutical preparation for oral administration |
JPH01238537A (en) * | 1988-03-18 | 1989-09-22 | Toyo Jozo Co Ltd | Remedy for hepatic disorder |
JPH0420285A (en) * | 1990-05-15 | 1992-01-23 | Asahi Chem Ind Co Ltd | Sod derivative |
CA2072934C (en) * | 1991-07-19 | 2007-08-28 | Karl William Aston | Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
US5834509A (en) * | 1992-12-07 | 1998-11-10 | Eukarion, Inc. | Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease |
US6204259B1 (en) * | 1993-01-14 | 2001-03-20 | Monsanto Company | Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
US5747026A (en) * | 1993-10-15 | 1998-05-05 | University Of Alabama At Birmingham Research Foundation | Antioxidants |
WO1995031197A1 (en) * | 1994-05-13 | 1995-11-23 | Monsanto Company | Methods of use for peroxynitrite decomposition catalysts, pharmaceutical compositions therefor |
DE69813898T2 (en) * | 1997-11-03 | 2004-03-11 | Duke University | SUBSTITUTED PORPHYRINES |
WO2000023568A2 (en) * | 1998-10-06 | 2000-04-27 | Albert Einstein College Of Medicine Of Yeshiva University | Methods and compositions for decreasing mitochondrial overproduction of reactive oxygen species in cells |
WO2000043498A2 (en) * | 1999-01-19 | 2000-07-27 | University Of North Carolina At Chapel Hill | Human liver progenitors |
ATE312103T1 (en) * | 1999-01-25 | 2005-12-15 | Nat Jewish Med & Res Center | SUBSTITUTED PORPHYRINS AND THEIR THERAPEUTIC USES |
-
2000
- 2000-03-28 FR FR0003887A patent/FR2806911B1/en not_active Expired - Fee Related
-
2001
- 2001-03-28 DE DE60113078T patent/DE60113078T2/en not_active Expired - Fee Related
- 2001-03-28 EP EP01919589A patent/EP1267881B1/en not_active Expired - Lifetime
- 2001-03-28 WO PCT/FR2001/000939 patent/WO2001072327A2/en active IP Right Grant
- 2001-03-28 JP JP2001570288A patent/JP2003528152A/en active Pending
- 2001-03-28 CA CA002404077A patent/CA2404077A1/en not_active Abandoned
- 2001-03-28 AT AT01919589T patent/ATE303151T1/en not_active IP Right Cessation
- 2001-03-28 AU AU2001246657A patent/AU2001246657A1/en not_active Abandoned
- 2001-03-28 US US10/240,270 patent/US20030118577A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE303151T1 (en) | 2005-09-15 |
WO2001072327A2 (en) | 2001-10-04 |
CA2404077A1 (en) | 2001-10-04 |
WO2001072327A3 (en) | 2002-03-28 |
US20030118577A1 (en) | 2003-06-26 |
EP1267881A2 (en) | 2003-01-02 |
FR2806911B1 (en) | 2003-01-10 |
EP1267881B1 (en) | 2005-08-31 |
DE60113078T2 (en) | 2006-07-13 |
FR2806911A1 (en) | 2001-10-05 |
JP2003528152A (en) | 2003-09-24 |
DE60113078D1 (en) | 2005-10-06 |
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