AU2001234608A1 - Methods for analysis of gene expression - Google Patents

Methods for analysis of gene expression

Info

Publication number
AU2001234608A1
AU2001234608A1 AU2001234608A AU3460801A AU2001234608A1 AU 2001234608 A1 AU2001234608 A1 AU 2001234608A1 AU 2001234608 A AU2001234608 A AU 2001234608A AU 3460801 A AU3460801 A AU 3460801A AU 2001234608 A1 AU2001234608 A1 AU 2001234608A1
Authority
AU
Australia
Prior art keywords
analysis
methods
gene expression
gene
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001234608A
Inventor
Christine Loehrlein
Joseph A. Monforte
Dan Pollart
Thomas Shaler
Kathy Stephens
Yuping Tan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetrace Systems Inc
Original Assignee
Genetrace Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetrace Systems Inc filed Critical Genetrace Systems Inc
Publication of AU2001234608A1 publication Critical patent/AU2001234608A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
AU2001234608A 2000-01-28 2001-01-27 Methods for analysis of gene expression Abandoned AU2001234608A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17900600P 2000-01-28 2000-01-28
US60179006 2000-01-28
PCT/US2001/002757 WO2001055454A1 (en) 2000-01-28 2001-01-27 Methods for analysis of gene expression

Publications (1)

Publication Number Publication Date
AU2001234608A1 true AU2001234608A1 (en) 2001-08-07

Family

ID=22654838

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001234608A Abandoned AU2001234608A1 (en) 2000-01-28 2001-01-27 Methods for analysis of gene expression

Country Status (5)

Country Link
US (4) US6618679B2 (en)
EP (1) EP1257664A4 (en)
AU (1) AU2001234608A1 (en)
CA (1) CA2398107C (en)
WO (1) WO2001055454A1 (en)

Families Citing this family (192)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69830598T2 (en) 1997-01-31 2006-05-18 The Horticulture And Food Research Institute Of New Zealand Limited OPTICAL DEVICE AND METHOD
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
CA2338194C (en) 1998-07-30 2013-09-10 Edward L. Squires Equine system for non-surgical artificial insemination
US20060275782A1 (en) 1999-04-20 2006-12-07 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
CA2290731A1 (en) 1999-11-26 2001-05-26 D. Jed Harrison Apparatus and method for trapping bead based reagents within microfluidic analysis system
US6432290B1 (en) 1999-11-26 2002-08-13 The Governors Of The University Of Alberta Apparatus and method for trapping bead based reagents within microfluidic analysis systems
WO2001055454A1 (en) * 2000-01-28 2001-08-02 Althea Technologies, Inc. Methods for analysis of gene expression
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
US8076063B2 (en) 2000-02-07 2011-12-13 Illumina, Inc. Multiplexed methylation detection methods
US7955794B2 (en) 2000-09-21 2011-06-07 Illumina, Inc. Multiplex nucleic acid reactions
US20080085515A1 (en) * 2000-03-24 2008-04-10 Eppendorf Array Technologies Sa (Eat) Identification of multiple biological (micro) organisms by detection of their nucleotide sequences on arrays
CA2408939C (en) 2000-05-09 2011-11-08 Xy, Inc. High purity x-chromosome bearing and y-chromosome bearing populations of spermatozoa
US7087414B2 (en) 2000-06-06 2006-08-08 Applera Corporation Methods and devices for multiplexing amplification reactions
US6927037B2 (en) * 2000-06-22 2005-08-09 Pharmacia Corporation Ion-exchange resin/enzyme activity assay
US7494817B2 (en) * 2000-09-06 2009-02-24 Transnet Yx, Inc. Methods for genotype screening using magnetic particles
AU2002220018A1 (en) 2000-11-29 2002-06-11 Colorado State University System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US20020155589A1 (en) * 2001-03-30 2002-10-24 Fuji Photo Film Co., Ltd. Biochemical analysis unit and biochemical analyzing method using the same
US20050015206A1 (en) * 2001-07-16 2005-01-20 Uwe Scherf Nucleic acid detection assay control genes
US20030096277A1 (en) * 2001-08-30 2003-05-22 Xiangning Chen Allele specific PCR for genotyping
AU2002341752B2 (en) 2001-09-19 2008-04-03 Alexion Pharmaceuticals, Inc. Engineered templates and their use in single primer amplification
US7414111B2 (en) 2001-09-19 2008-08-19 Alexion Pharmaceuticals, Inc. Engineered templates and their use in single primer amplification
US7358043B2 (en) * 2001-10-16 2008-04-15 Duke University Proteomic interaction and genomic action determinations in the presence of associated redox state conditions
US20030077611A1 (en) * 2001-10-24 2003-04-24 Sention Methods and systems for dynamic gene expression profiling
EP1468117A2 (en) * 2002-01-15 2004-10-20 MATFORSK, Norwegian Food Research Institute Methods of nucleic acid amplification
JP4426309B2 (en) * 2002-02-20 2010-03-03 シスメックス株式会社 Primer for nucleic acid amplification for detection of mRNA of housekeeping gene and test method using the primer
EP3115470B1 (en) 2002-03-13 2018-07-18 Genomic Health, Inc. Gene expression profiling in biopsied tumor tissues
US7445893B2 (en) * 2002-04-12 2008-11-04 Primera Biosystems, Inc. Sampling method for amplification reaction analysis
US7081339B2 (en) * 2002-04-12 2006-07-25 Primera Biosystems, Inc. Methods for variation detection
US7785776B2 (en) * 2002-05-13 2010-08-31 Idaho Technology, Inc. Genotyping by amplicon melting curve analysis
US20030217923A1 (en) * 2002-05-24 2003-11-27 Harrison D. Jed Apparatus and method for trapping bead based reagents within microfluidic analysis systems
ATE489477T1 (en) * 2002-06-28 2010-12-15 Primeradx Inc METHOD FOR DETECTING SEQUENCE DIFFERENCES
US7582260B2 (en) * 2002-07-18 2009-09-01 Montana State University Zwitterionic dyes for labeling in proteomic and other biological analyses
DE60332948D1 (en) 2002-07-19 2010-07-22 Althea Technologies Inc STRATEGIES FOR GENE EXPRESSION ANALYSIS
FR2842534B1 (en) * 2002-07-19 2006-01-20 Inst Nat Sante Rech Med GENOME-BASED QUANTITATIVE MULTIPLEX AMPLIFICATION AND APPLICATIONS FOR DETECTION OF GENOMIC REMANIATION
MXPA05001100A (en) 2002-08-01 2005-04-28 Xy Inc Low pressure sperm cell separation system.
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
WO2004017041A2 (en) 2002-08-15 2004-02-26 Xy, Inc. High resolution flow cytometer
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
WO2004029221A2 (en) 2002-09-27 2004-04-08 The General Hospital Corporation Microfluidic device for cell separation and uses thereof
US7229762B2 (en) * 2002-10-15 2007-06-12 Duke University Medical Center Proteomic screening for redox state dependent protein—protein interactions
JP4606879B2 (en) * 2002-11-15 2011-01-05 ジェノミック ヘルス， インコーポレイテッド Gene expression profiling of EGFR positive cancer
AU2003291144A1 (en) * 2002-11-21 2004-06-18 Primera Biosystems Sampling method and apparatus for amplification reaction analysis
EP2031070B1 (en) * 2002-12-04 2013-07-17 Life Technologies Corporation Multiplex amplification of polynucleotides
JP2006512092A (en) 2002-12-30 2006-04-13 ザ・リージェンツ・オブ・ジ・ユニバーシティ・オブ・カリフォルニア Method and apparatus for pathogen detection and analysis
US7122153B2 (en) * 2003-01-08 2006-10-17 Ho Winston Z Self-contained microfluidic biochip and apparatus
US20050221281A1 (en) * 2003-01-08 2005-10-06 Ho Winston Z Self-contained microfluidic biochip and apparatus
WO2004063389A2 (en) * 2003-01-10 2004-07-29 Primera Biosystems, Inc. Methods of detecting differences in genomic sequence representation
US20040231909A1 (en) 2003-01-15 2004-11-25 Tai-Yang Luh Motorized vehicle having forward and backward differential structure
EP1590487A2 (en) * 2003-02-06 2005-11-02 Genomic Health, Inc. Gene expression markers for response to egfr inhibitor drugs
JP4568716B2 (en) * 2003-02-20 2010-10-27 ジェノミック ヘルス， インコーポレイテッド Use of intron RNA to measure gene expression
DK2309245T3 (en) 2003-03-28 2016-01-04 Inguran Llc Methods for providing sex-sorted animal semen
NZ544103A (en) 2003-05-15 2010-10-29 Xy Llc Efficient haploid cell sorting for flow cytometer systems
CA2527285A1 (en) * 2003-05-28 2004-12-23 Genomic Health, Inc. Gene expression markers for predicting response to chemotherapy
WO2004111273A2 (en) * 2003-05-30 2004-12-23 Genomic Health, Inc. Gene expression markers for response to egfr inhibitor drugs
US20040248102A1 (en) 2003-06-03 2004-12-09 Diane Ilsley-Tyree Methods and compositions for performing template dependent nucleic acid primer extension reactions that produce a reduced complexity product
EP3470535B1 (en) 2003-06-24 2020-04-01 Genomic Health, Inc. Prediction of likelihood of cancer recurrence
WO2005008213A2 (en) * 2003-07-10 2005-01-27 Genomic Health, Inc. Expression profile algorithm and test for cancer prognosis
ATE461292T1 (en) * 2003-09-10 2010-04-15 Althea Technologies Inc CREATION OF EXPRESSION PROFILES USING MICROARRAYS
US20050095634A1 (en) * 2003-10-16 2005-05-05 Genomic Health Inc. qRT-PCR assay system for gene expression profiling
WO2005064019A2 (en) 2003-12-23 2005-07-14 Genomic Health, Inc. Universal amplification of fragmented rna
WO2005071078A1 (en) * 2004-01-12 2005-08-04 Nimblegen Systems Inc. Method of performing pcr amplification on a microarray
GB2410796A (en) * 2004-02-05 2005-08-10 Selecgen Ltd Sequence specific DNA analysis
US8304192B2 (en) 2004-03-05 2012-11-06 University Of Toledo Methods and compositions for assessing nucleic acids and alleles
US7432055B2 (en) * 2004-03-05 2008-10-07 Uchicago Argonne Llc Dual phase multiplex polymerase chain reaction
ATE431433T1 (en) 2004-03-24 2009-05-15 Applied Biosystems Llc LIGATION AND AMPLIFICATION REACTIONS TO DETERMINE TARGET MOLECULES
EP2151243B1 (en) 2004-03-29 2012-10-24 Inguran, LLC Sperm suspensions for sorting into X or Y chromosome-bearing enriched populations
ES2550614T3 (en) * 2004-04-09 2015-11-11 Genomic Health, Inc. Gene expression markers to predict the response to chemotherapy
US7476502B2 (en) 2004-04-12 2009-01-13 Willey James C Methods and compositions for assaying analytes
FI20040723A0 (en) * 2004-05-26 2004-05-26 Orpana Aarne Method for a quantitative and / or relative measurement of mRNA expression levels in small biological samples
EP2471924A1 (en) 2004-05-28 2012-07-04 Asuragen, INC. Methods and compositions involving microRNA
US7799553B2 (en) * 2004-06-01 2010-09-21 The Regents Of The University Of California Microfabricated integrated DNA analysis system
CA2574499C (en) 2004-07-22 2016-11-29 Monsanto Technology Llc Process for enriching a population of sperm cells
US7542854B2 (en) * 2004-07-22 2009-06-02 International Business Machines Corporation Method for discovering gene regulatory models and genetic networks using relational fuzzy models
EP2261650A3 (en) 2004-09-15 2011-07-06 IntegenX Inc. Microfluidic devices
US20060078894A1 (en) * 2004-10-12 2006-04-13 Winkler Matthew M Methods and compositions for analyzing nucleic acids
MX2007005364A (en) * 2004-11-03 2008-01-22 Third Wave Tech Inc Single step detection assay.
WO2006052731A2 (en) 2004-11-05 2006-05-18 Genomic Health, Inc. Molecular indicators of breast cancer prognosis and prediction of treatment response
CA3061785A1 (en) * 2004-11-05 2006-05-18 Genomic Health, Inc. Predicting response to chemotherapy using gene expression markers
EP2302055B1 (en) 2004-11-12 2014-08-27 Asuragen, Inc. Methods and compositions involving miRNA and miRNA inhibitor molecules
WO2006065971A2 (en) * 2004-12-15 2006-06-22 Primera Biosystem, Inc. Compositions and methods for polynucleotide amplification and detection
WO2006099579A2 (en) * 2005-03-16 2006-09-21 Applera Corporation Compositions and methods for clonal amplification and analysis of polynucleotides
JP5280841B2 (en) * 2005-05-03 2013-09-04 アルセア・ディーエックス，インク． Composition and method for analysis of degraded nucleic acids
US20090317798A1 (en) * 2005-06-02 2009-12-24 Heid Christian A Analysis using microfluidic partitioning devices
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
AU2006287548A1 (en) * 2005-09-06 2007-03-15 Gen-Probe Incorporated Methods, compositions and kits for isothermal amplification of nucleic acids
WO2007035684A2 (en) * 2005-09-16 2007-03-29 Primera Biosystems, Inc. Method for quantitative detection of short rna molecules
US8831887B2 (en) * 2005-10-12 2014-09-09 The Research Foundation For The State University Of New York Absolute PCR quantification
JP2009514551A (en) * 2005-11-09 2009-04-09 プリメーラ バイオシステムズ インコーポレーティッド Multiple quantitative detection method for pathogens
US7749365B2 (en) 2006-02-01 2010-07-06 IntegenX, Inc. Optimized sample injection structures in microfluidic separations
JP5063616B2 (en) 2006-02-03 2012-10-31 インテジェニックス インコーポレイテッド Microfluidic device
US20070207483A1 (en) * 2006-03-02 2007-09-06 Bio-Rad Laboratories, Inc. BUFFERS FOR DETECTION OF mRNA SEPARATED IN A MICROFLUIDIC DEVICE
US7766033B2 (en) 2006-03-22 2010-08-03 The Regents Of The University Of California Multiplexed latching valves for microfluidic devices and processors
US7888044B2 (en) 2006-04-10 2011-02-15 Trustees Of Boston University Melanoma biomarker and methods of uses
WO2007130967A2 (en) 2006-05-01 2007-11-15 Siemens Healthcare Diagnostics Inc. Novel oligonucleotide primers and methods for dna replication
EP2636755A1 (en) 2006-05-26 2013-09-11 AltheaDx Incorporated Biochemical analysis of partitioned cells
US7833716B2 (en) 2006-06-06 2010-11-16 Gen-Probe Incorporated Tagged oligonucleotides and their use in nucleic acid amplification methods
US8137912B2 (en) 2006-06-14 2012-03-20 The General Hospital Corporation Methods for the diagnosis of fetal abnormalities
CA2655272C (en) * 2006-06-14 2017-04-18 Living Microsystems, Inc. Rare cell analysis using sample splitting and dna tags
US20080050739A1 (en) 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
WO2008111990A1 (en) * 2006-06-14 2008-09-18 Cellpoint Diagnostics, Inc. Rare cell analysis using sample splitting and dna tags
WO2007147074A2 (en) 2006-06-14 2007-12-21 Living Microsystems, Inc. Use of highly parallel snp genotyping for fetal diagnosis
US8372584B2 (en) * 2006-06-14 2013-02-12 The General Hospital Corporation Rare cell analysis using sample splitting and DNA tags
DE602007013405D1 (en) * 2006-07-14 2011-05-05 Us Government METHOD FOR DETERMINING THE PROGNOSIS OF ADENOCARCINOMA
JP2009545314A (en) * 2006-08-03 2009-12-24 ナショナル ユニヴァーシティー オブ シンガポール Nucleic acid multiplex analysis method
CA2661640A1 (en) * 2006-08-24 2008-02-28 University Of Massachusetts Medical School Mapping of genomic interactions
WO2008048986A2 (en) * 2006-10-17 2008-04-24 Children's Hospital Medical Center Gene array technique for predicting response in inflammatory bowel diseases
WO2008052138A2 (en) * 2006-10-25 2008-05-02 The Regents Of The University Of California Inline-injection microdevice and microfabricated integrated dna analysis system using same
US20080131878A1 (en) * 2006-12-05 2008-06-05 Asuragen, Inc. Compositions and Methods for the Detection of Small RNA
AU2007333106A1 (en) * 2006-12-08 2008-06-19 Asuragen, Inc. miR-20 regulated genes and pathways as targets for therapeutic intervention
WO2008080029A2 (en) * 2006-12-21 2008-07-03 Gen-Probe Incorporated Methods and compositions for nucleic acid amplification
WO2008115626A2 (en) 2007-02-05 2008-09-25 Microchip Biotechnologies, Inc. Microfluidic and nanofluidic devices, systems, and applications
CN101646783B (en) * 2007-02-21 2014-11-05 奥斯陆大学医院Hf New markers for cancer
EP3543357A1 (en) 2007-05-08 2019-09-25 Trustees of Boston University Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof
WO2009015296A1 (en) 2007-07-24 2009-01-29 The Regents Of The University Of California Microfabricated dropley generator
ES2331499B1 (en) * 2007-08-02 2010-10-14 Fundacion Publica Andaluza Para La Gestion De La Investigacion En Salud En Sevilla (Fund.Sevilla) PRIMERS, PROCEDURE AND SET OF USEFULS FOR THE DETERMINATION OF THE FUNCTIONALITY OF THE HUMAN TIMO.
EP2198050A1 (en) 2007-09-14 2010-06-23 Asuragen, INC. Micrornas differentially expressed in cervical cancer and uses thereof
CA2700233A1 (en) * 2007-10-22 2009-04-30 Monoquant Pty Ltd. A method of dna amplification
DE602007007927D1 (en) * 2007-11-05 2010-09-02 Agilent Technologies Inc Freezing a microfluidic chip
WO2009070805A2 (en) 2007-12-01 2009-06-04 Asuragen, Inc. Mir-124 regulated genes and pathways as targets for therapeutic intervention
EP2234916A4 (en) 2008-01-22 2016-08-10 Integenx Inc Universal sample preparation system and use in an integrated analysis system
WO2009099854A1 (en) * 2008-02-01 2009-08-13 Siemens Healthcare Diagnostics Inc. Urine transport medium
GB0809069D0 (en) 2008-05-19 2008-06-25 Univ Leuven Kath Gene signatures
US8258111B2 (en) 2008-05-08 2012-09-04 The Johns Hopkins University Compositions and methods related to miRNA modulation of neovascularization or angiogenesis
EP2291533B2 (en) 2008-07-02 2020-09-30 Illumina Cambridge Limited Using populations of beads for the fabrication of arrays on surfaces
WO2010027870A2 (en) * 2008-08-26 2010-03-11 Fluidigm Corporation Assay methods for increased throughput of samples and/or targets
CA3069081C (en) 2008-09-20 2023-05-23 The Board Of Trustees Of The Leland Stanford Junior University Noninvasive diagnosis of fetal aneuploidy by sequencing
CN102341691A (en) 2008-12-31 2012-02-01 尹特根埃克斯有限公司 Instrument with microfluidic chip
US8691509B2 (en) 2009-04-02 2014-04-08 Fluidigm Corporation Multi-primer amplification method for barcoding of target nucleic acids
EP2438154A1 (en) 2009-06-02 2012-04-11 Integenx Inc. Fluidic devices with diaphragm valves
KR20120031218A (en) 2009-06-05 2012-03-30 인터젠엑스 인크. Universal sample preparation system and use in an integrated analysis system
EP2449132B1 (en) 2009-07-01 2015-05-13 Gen-Probe Incorporated Methods and compositions for nucleic acid amplification
EP2272976A1 (en) * 2009-07-06 2011-01-12 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Method for differentiation of polynucleotide strands
EP2483680A4 (en) 2009-09-30 2014-01-01 Quantapore Inc Ultrafast sequencing of biological polymers using a labeled nanopore
US9175339B2 (en) * 2009-10-29 2015-11-03 Ngk Insulators, Ltd. Method for detection of target nucleic acid
US8584703B2 (en) 2009-12-01 2013-11-19 Integenx Inc. Device with diaphragm valve
EP2513137B1 (en) 2009-12-17 2018-02-28 Children's Medical Center Corporation Saposin-a derived peptides and uses thereof
US20110312503A1 (en) 2010-01-23 2011-12-22 Artemis Health, Inc. Methods of fetal abnormality detection
US8512538B2 (en) 2010-05-28 2013-08-20 Integenx Inc. Capillary electrophoresis device
US20130040375A1 (en) 2011-08-08 2013-02-14 Tandem Diagnotics, Inc. Assay systems for genetic analysis
US10533223B2 (en) 2010-08-06 2020-01-14 Ariosa Diagnostics, Inc. Detection of target nucleic acids using hybridization
US20130261003A1 (en) 2010-08-06 2013-10-03 Ariosa Diagnostics, In. Ligation-based detection of genetic variants
US20120034603A1 (en) * 2010-08-06 2012-02-09 Tandem Diagnostics, Inc. Ligation-based detection of genetic variants
US20140342940A1 (en) 2011-01-25 2014-11-20 Ariosa Diagnostics, Inc. Detection of Target Nucleic Acids using Hybridization
US11203786B2 (en) 2010-08-06 2021-12-21 Ariosa Diagnostics, Inc. Detection of target nucleic acids using hybridization
US8700338B2 (en) 2011-01-25 2014-04-15 Ariosa Diagnosis, Inc. Risk calculation for evaluation of fetal aneuploidy
US10167508B2 (en) * 2010-08-06 2019-01-01 Ariosa Diagnostics, Inc. Detection of genetic abnormalities
WO2012024658A2 (en) 2010-08-20 2012-02-23 IntegenX, Inc. Integrated analysis system
WO2012024657A1 (en) 2010-08-20 2012-02-23 IntegenX, Inc. Microfluidic devices with mechanically-sealed diaphragm valves
JP2013545439A (en) 2010-09-17 2013-12-26 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ Functional genomics assay to characterize the usefulness and safety of pluripotent stem cells
US9074204B2 (en) 2011-05-20 2015-07-07 Fluidigm Corporation Nucleic acid encoding reactions
CA2839896A1 (en) 2011-06-21 2012-12-27 Alnylam Pharmaceuticals, Inc. Assays and methods for determining activity of a therapeutic agent in a subject
JP2014527036A (en) 2011-06-27 2014-10-09 ザ ジャクソン ラボラトリー Methods and compositions for the treatment of cancer and autoimmune diseases
WO2013040251A2 (en) 2011-09-13 2013-03-21 Asurgen, Inc. Methods and compositions involving mir-135b for distinguishing pancreatic cancer from benign pancreatic disease
WO2013055911A1 (en) 2011-10-14 2013-04-18 Dana-Farber Cancer Institute, Inc. Znf365/zfp365 biomarker predictive of anti-cancer response
US10865440B2 (en) 2011-10-21 2020-12-15 IntegenX, Inc. Sample preparation, processing and analysis systems
US20150136604A1 (en) 2011-10-21 2015-05-21 Integenx Inc. Sample preparation, processing and analysis systems
KR102035877B1 (en) 2011-11-14 2019-10-23 알파시그마 에스.피.에이. Assays for selecting a treatment regimen for a subject with depression and methods for treatment
AU2012358269B2 (en) 2011-12-22 2017-11-02 Children's Medical Center Corporation Saposin-A derived peptides and uses thereof
WO2013122826A1 (en) * 2012-02-14 2013-08-22 Gnubio, Inc. Cascaded addition of target specific universal adapters to nucleic acids
CA2874343C (en) 2012-05-21 2021-11-09 Fluidigm Corporation Single-particle analysis of particle populations
FR2994443B1 (en) 2012-08-10 2015-02-27 Commissariat Energie Atomique PROCESS FOR SYNTHESIS OF NANOSTRUCTURE COMPOSITE MATERIAL AND ASSOCIATED IMPLEMENTATION DEVICE
US9651539B2 (en) 2012-10-28 2017-05-16 Quantapore, Inc. Reducing background fluorescence in MEMS materials by low energy ion beam treatment
US9523121B2 (en) 2013-01-13 2016-12-20 Uni Taq Bio Methods and compositions for PCR using blocked and universal primers
CN105283560B (en) 2013-05-24 2018-11-30 昆塔波尔公司 The foranalysis of nucleic acids detected by mixed FRET based on nano-pore
WO2014200905A2 (en) 2013-06-10 2014-12-18 President And Fellows Of Harvard College Early developmental genomic assay for characterizing pluripotent stem cell utility and safety
WO2015073999A1 (en) 2013-11-18 2015-05-21 Integenx Inc. Cartridges and instruments for sample analysis
CA2944903A1 (en) 2014-04-24 2015-10-29 Dana-Farber Cancer Institute, Inc. Tumor suppressor and oncogene biomarkers predictive of anti-immune checkpoint inhibitor response
WO2015168831A1 (en) * 2014-05-04 2015-11-12 Ningbo Health Gene Technologies Co., Ltd. Methods and compositions for detecting expression of target genes
US10208332B2 (en) 2014-05-21 2019-02-19 Integenx Inc. Fluidic cartridge with valve mechanism
ES2870096T3 (en) 2014-06-19 2021-10-26 Memorial Sloan Kettering Cancer Center Biomarkers of response to EZH2 inhibitors
EP3169691B1 (en) 2014-07-17 2020-09-02 The Trustees Of The University Of Pennsylvania Methods for using exosomes to monitor transplanted organ status
JP6649367B2 (en) * 2014-09-17 2020-02-19 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Nucleic acid target identification by structure-based probe cleavage
CN107109472B (en) 2014-10-10 2021-05-11 昆塔波尔公司 Nanopore-based polymer analysis using mutually quenching fluorescent labels
EP3209410A4 (en) 2014-10-22 2018-05-02 IntegenX Inc. Systems and methods for sample preparation, processing and analysis
JP6757316B2 (en) 2014-10-24 2020-09-16 クアンタポール， インコーポレイテッド Efficient optical analysis of polymers using nanostructured arrays
WO2016144673A1 (en) 2015-03-06 2016-09-15 Dana-Farber Cancer Institute, Inc. Pd-l2 biomarkers predictive of pd-1 pathway inhibitor responses in esophagogastric cancers
WO2016181128A1 (en) * 2015-05-11 2016-11-17 Genefirst Ltd Methods, compositions, and kits for preparing sequencing library
US20170145486A1 (en) 2015-11-25 2017-05-25 Integrated Dna Technologies, Inc. Methods for variant detection
CN108603224B (en) 2015-12-16 2022-06-28 富鲁达公司 High level multiplexed amplification
CN105925678B (en) * 2016-05-06 2021-10-12 艾吉泰康生物科技(北京)有限公司 Primer group for amplifying multiple target DNA sequences in sample and application thereof
EP3482196B1 (en) 2016-07-05 2022-02-23 Quantapore, Inc. Optically based nanopore sequencing
CN106295246A (en) * 2016-08-07 2017-01-04 吉林大学 Find the lncRNA relevant to tumor and predict its function
WO2019094578A1 (en) 2017-11-09 2019-05-16 Alnylam Pharmaceuticals Inc. Assays and methods for determining expression of the lect2 gene
WO2019094798A1 (en) 2017-11-10 2019-05-16 The Trustees Of Columbia University In The City Of New York Methods and compositions for promoting or inducing hair growth
US20190352712A1 (en) * 2018-05-04 2019-11-21 Shoreline Biome, Llc Multiple Specific/Nonspecific Primers for PCR of a Complex Gene Pool
WO2020096679A1 (en) * 2018-11-06 2020-05-14 North Carolina State University Non-destructively storing, accessing, and editing information using nucleic acids
US20240024377A1 (en) 2020-10-29 2024-01-25 Evelo Biosciences, Inc. Compositions comprising spirulina components
WO2022251166A2 (en) 2021-05-25 2022-12-01 Evelo Biosciences, Inc. Bacterial compositions comprising soy hemoglobin
WO2023097119A2 (en) 2021-11-29 2023-06-01 Dana-Farber Cancer Institute, Inc. Methods and compositions to modulate riok2
WO2024006991A1 (en) * 2022-06-30 2024-01-04 The Regents Of The University Of California Methods and compositions to detect chemical adducts on oligonucleotides

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883750A (en) 1984-12-13 1989-11-28 Applied Biosystems, Inc. Detection of specific sequences in nucleic acids
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
AU622426B2 (en) 1987-12-11 1992-04-09 Abbott Laboratories Assay using template-dependent nucleic acid probe reorganization
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US6136535A (en) * 1991-11-14 2000-10-24 Digene Corporation Continuous amplification reaction
WO1993018176A1 (en) 1992-03-11 1993-09-16 Dana-Farber Cancer Institute METHODS TO CLONE mRNA
US5296375A (en) 1992-05-01 1994-03-22 Trustees Of The University Of Pennsylvania Mesoscale sperm handling devices
US5304487A (en) 1992-05-01 1994-04-19 Trustees Of The University Of Pennsylvania Fluid handling in mesoscale analytical devices
US5639423A (en) 1992-08-31 1997-06-17 The Regents Of The University Of Calfornia Microfabricated reactor
DE69433811T2 (en) 1993-01-07 2005-06-23 Sequenom, Inc., San Diego DNA SEQUENCING BY MASS SPECTROMONY
US5876978A (en) * 1993-04-06 1999-03-02 Medical College Of Ohio Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction
US5714320A (en) 1993-04-15 1998-02-03 University Of Rochester Rolling circle synthesis of oligonucleotides and amplification of select randomized circular oligonucleotides
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US5834181A (en) * 1994-07-28 1998-11-10 Genzyme Corporation High throughput screening method for sequences or genetic alterations in nucleic acids
US5700642A (en) 1995-05-22 1997-12-23 Sri International Oligonucleotide sizing using immobilized cleavable primers
US5830655A (en) 1995-05-22 1998-11-03 Sri International Oligonucleotide sizing using cleavable primers
US5882856A (en) * 1995-06-07 1999-03-16 Genzyme Corporation Universal primer sequence for multiplex DNA amplification
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US5866330A (en) 1995-09-12 1999-02-02 The Johns Hopkins University School Of Medicine Method for serial analysis of gene expression
US5972693A (en) * 1995-10-24 1999-10-26 Curagen Corporation Apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
US5784157A (en) * 1995-11-21 1998-07-21 The Research Foundation Of State University Of New York Method and apparatus for identifying fluorophores
KR100473903B1 (en) 1996-01-23 2005-09-30 퀴아진 지노믹스, 인코포레이티드 How to detect binding of ligand pairs
EP2369007B1 (en) * 1996-05-29 2015-07-29 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
US6124092A (en) 1996-10-04 2000-09-26 The Perkin-Elmer Corporation Multiplex polynucleotide capture methods and compositions
US20030049636A1 (en) * 1999-05-03 2003-03-13 Bergeron Michel G. Species-specific, genus-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial and fungal pathogens and associated antibiotic resistance genes from clinical specimens for diagnosis in microbiology laboratories
JP2002505737A (en) 1997-02-14 2002-02-19 ジョージワシントン大学 Analysis for measuring DNA synthesis rate
US5989872A (en) * 1997-08-12 1999-11-23 Clontech Laboratories, Inc. Methods and compositions for transferring DNA sequence information among vectors
WO1999014375A2 (en) 1997-09-19 1999-03-25 Genetrace Systems, Inc. Dna typing by mass spectrometry with polymorphic dna repeat markers
WO1999029901A1 (en) * 1997-12-11 1999-06-17 The General Hospital Corporation Broad range pcr amplification techniques
US6232066B1 (en) * 1997-12-19 2001-05-15 Neogen, Inc. High throughput assay system
US6104028A (en) 1998-05-29 2000-08-15 Genetrace Systems Inc. Volatile matrices for matrix-assisted laser desorption/ionization mass spectrometry
EP2045334A1 (en) * 1998-06-24 2009-04-08 Illumina, Inc. Decoding of array sensors with microspheres
US6074831A (en) 1998-07-09 2000-06-13 Agilent Technologies, Inc. Partitioning of polymorphic DNAs
US6132685A (en) * 1998-08-10 2000-10-17 Caliper Technologies Corporation High throughput microfluidic systems and methods
US6140054A (en) * 1998-09-30 2000-10-31 University Of Utah Research Foundation Multiplex genotyping using fluorescent hybridization probes
WO2001055454A1 (en) * 2000-01-28 2001-08-02 Althea Technologies, Inc. Methods for analysis of gene expression
AU2001238068A1 (en) * 2000-02-07 2001-08-14 Illumina, Inc. Nucleic acid detection methods using universal priming
AU2001247328C1 (en) * 2000-03-08 2006-10-26 Datascope Investment Corp. Methods for assay and detection on a microarray
US7138506B2 (en) * 2001-05-09 2006-11-21 Genetic Id, Na, Inc. Universal microarray system
DE60332948D1 (en) * 2002-07-19 2010-07-22 Althea Technologies Inc STRATEGIES FOR GENE EXPRESSION ANALYSIS

Also Published As

Publication number Publication date
US20090148838A1 (en) 2009-06-11
US20030204322A1 (en) 2003-10-30
EP1257664A4 (en) 2006-04-05
US6618679B2 (en) 2003-09-09
EP1257664A1 (en) 2002-11-20
WO2001055454A1 (en) 2001-08-02
US20160138087A1 (en) 2016-05-19
US20020160361A1 (en) 2002-10-31
CA2398107C (en) 2013-11-19
CA2398107A1 (en) 2001-08-02

Similar Documents

Publication Publication Date Title
AU2001234608A1 (en) Methods for analysis of gene expression
AU785425C (en) Methods of genomic analysis
AU2002365212A1 (en) Gene expression analysis using nicking agents
AU2001253310A1 (en) Methods for the survey and genetic analysis of populations
AU4640400A (en) Analysis of differential protein expression
AU2002312859A1 (en) Method for determining gene expression
AU2002214126A1 (en) Genetic analysis of microorganisms
AU2001271841A1 (en) Methods for identifying combinations of drugs
AU6387000A (en) Serial analysis of genetic alterations
AU2002222618A1 (en) Method of analyzing gene expression
AU2002364749A1 (en) Method for protein expression analysis
AU2261802A (en) Method of analyzing gene expression
AU3972899A (en) Analysis of gene family expression
AU2928400A (en) Analysis of differential gene expression
EP1349961A4 (en) Methods for determining the biological effects of compounds on gene expression
AU2001269077A1 (en) Methods and means for regulation of gene expression
AU2002221104A1 (en) Method of detecting relation between genes
AU2001292468A1 (en) Methods and means of rna analysis
AU2002249789A1 (en) Methods and reagents for analysis of rna structure and function
AU2002351532A1 (en) Method of sampling
AU2002213695A1 (en) Method of genomic analysis
AU2001257448A1 (en) Use of representations of dna for genetic analysis
AUPQ825300A0 (en) Method of sentence analysis
AU2002354255A1 (en) Mtehod of analyzing gene expression
AU2001293018A1 (en) Application of bioinformatics for direct study of unculturable microorganisms