AU2001233912A1 - Diagnosis of breast cancer using bcmp-81 as marker - Google Patents
Diagnosis of breast cancer using bcmp-81 as markerInfo
- Publication number
- AU2001233912A1 AU2001233912A1 AU2001233912A AU3391201A AU2001233912A1 AU 2001233912 A1 AU2001233912 A1 AU 2001233912A1 AU 2001233912 A AU2001233912 A AU 2001233912A AU 3391201 A AU3391201 A AU 3391201A AU 2001233912 A1 AU2001233912 A1 AU 2001233912A1
- Authority
- AU
- Australia
- Prior art keywords
- bcmp
- breast cancer
- diagnosis
- marker
- immunospecific
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 206010006187 Breast cancer Diseases 0.000 title abstract 3
- 208000026310 Breast neoplasm Diseases 0.000 title abstract 3
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 239000003550 marker Substances 0.000 title 1
- 206010060862 Prostate cancer Diseases 0.000 abstract 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 abstract 1
- 210000000170 cell membrane Anatomy 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
- A61K51/1051—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from breast, e.g. the antibody being herceptin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57419—Specifically defined cancers of colon
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Hospice & Palliative Care (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Optics & Photonics (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
The present invention provides the use of a protein found in breast cancer cell membranes, known as BCMP 11, in the diagnosis, screening, treatment and prophylaxis of breast cancer or prostate cancer, as well as compositions comprising BCMP 11, including vaccines and antibodies that are immunospecific for BCMP 11.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0004576 | 2000-02-25 | ||
GBGB0004576.5A GB0004576D0 (en) | 2000-02-25 | 2000-02-25 | Proteins |
PCT/GB2001/000727 WO2001063288A1 (en) | 2000-02-25 | 2001-02-21 | Diagnosis of breast cancer using bcmp-81 as marker |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001233912A1 true AU2001233912A1 (en) | 2001-09-03 |
Family
ID=9886470
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001233917A Abandoned AU2001233917A1 (en) | 2000-02-25 | 2001-02-21 | Bcmp-7 as marker for diagnosis of breast cancer |
AU2001233912A Abandoned AU2001233912A1 (en) | 2000-02-25 | 2001-02-21 | Diagnosis of breast cancer using bcmp-81 as marker |
AU2001235761A Abandoned AU2001235761A1 (en) | 2000-02-25 | 2001-02-21 | Diagnosis of breast cancer using bcmp-11 as marker |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001233917A Abandoned AU2001233917A1 (en) | 2000-02-25 | 2001-02-21 | Bcmp-7 as marker for diagnosis of breast cancer |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001235761A Abandoned AU2001235761A1 (en) | 2000-02-25 | 2001-02-21 | Diagnosis of breast cancer using bcmp-11 as marker |
Country Status (8)
Country | Link |
---|---|
US (2) | US20020111303A1 (en) |
EP (2) | EP1259814B1 (en) |
AT (1) | ATE306668T1 (en) |
AU (3) | AU2001233917A1 (en) |
DE (1) | DE60113968T2 (en) |
ES (1) | ES2249410T3 (en) |
GB (1) | GB0004576D0 (en) |
WO (3) | WO2001063290A1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0022978D0 (en) | 2000-09-19 | 2000-11-01 | Oxford Glycosciences Uk Ltd | Detection of peptides |
US7608696B2 (en) * | 2001-10-26 | 2009-10-27 | Dana-Farber Cancer Institute, Inc. | IBC-1 (invasive breast cancer-1), a putative oncogene amplified in breast cancer |
AU2003209459A1 (en) * | 2002-03-06 | 2003-09-16 | Hybrigenics | Protein-protein interactions in human tumours involving bcmp-7 and bcmp-11 |
GB0208331D0 (en) * | 2002-04-11 | 2002-05-22 | Oxford Glycosciences Uk Ltd | Proteins |
GB0222787D0 (en) * | 2002-10-02 | 2002-11-06 | Univ Liverpool | Metastasis inducing compounds |
WO2004056858A2 (en) * | 2002-12-23 | 2004-07-08 | Ingenium Pharmaceuticals Ag | Methods and agents for diagnosis and prevention, amelioration or treatment of goblet cell-related disorders |
JP2007504842A (en) | 2003-05-29 | 2007-03-08 | ミレニアム ファーマシューティカルズ, インコーポレイテッド | Compositions, kits and methods for identification, evaluation, prevention and treatment of breast cancer |
US20050277167A1 (en) * | 2004-03-11 | 2005-12-15 | Bachinger Hans P | Prolyl 3-hydroxylases |
GB0616929D0 (en) * | 2006-08-26 | 2006-10-04 | Univ Liverpool | Antibodies, assays and hybridomas |
WO2008104803A2 (en) * | 2007-02-26 | 2008-09-04 | Oxford Genome Sciences (Uk) Limited | Proteins |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3588043T2 (en) * | 1984-01-06 | 1996-03-21 | Univ California | CYTOKERATIN TUMOR MARKER AND TEST TO DETECT IT. |
WO1998007749A1 (en) * | 1996-08-23 | 1998-02-26 | Human Genome Sciences, Inc. | Novel human growth factors |
WO2000053755A2 (en) * | 1999-03-08 | 2000-09-14 | Genentech, Inc. | Compositions and methods for the treatment of tumor |
EP1021531A2 (en) * | 1997-10-08 | 2000-07-26 | Sagami Chemical Research Center | HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND cDNAs ENCODING THESE PROTEINS |
DE19817557A1 (en) * | 1998-04-09 | 1999-10-21 | Metagen Gesellschaft Fuer Genomforschung Mbh | Human nucleic acid sequences from ovarian tumor tissue |
CA2296792A1 (en) * | 1999-02-26 | 2000-08-26 | Genset S.A. | Expressed sequence tags and encoded human proteins |
AU3752700A (en) * | 1999-03-15 | 2000-10-04 | Eos Biotechnology, Inc. | Novel methods of diagnosing and treating breast cancer, compositions, and methods of screening for breast cancer modulators |
-
2000
- 2000-02-25 GB GBGB0004576.5A patent/GB0004576D0/en not_active Ceased
-
2001
- 2001-02-21 WO PCT/GB2001/000734 patent/WO2001063290A1/en active IP Right Grant
- 2001-02-21 AU AU2001233917A patent/AU2001233917A1/en not_active Abandoned
- 2001-02-21 ES ES01905953T patent/ES2249410T3/en not_active Expired - Lifetime
- 2001-02-21 EP EP01905953A patent/EP1259814B1/en not_active Expired - Lifetime
- 2001-02-21 WO PCT/GB2001/000727 patent/WO2001063288A1/en active Application Filing
- 2001-02-21 AU AU2001233912A patent/AU2001233912A1/en not_active Abandoned
- 2001-02-21 DE DE60113968T patent/DE60113968T2/en not_active Expired - Lifetime
- 2001-02-21 AT AT01905953T patent/ATE306668T1/en not_active IP Right Cessation
- 2001-02-21 EP EP01907893A patent/EP1257827A1/en not_active Withdrawn
- 2001-02-21 WO PCT/GB2001/000730 patent/WO2001063289A1/en not_active Application Discontinuation
- 2001-02-21 AU AU2001235761A patent/AU2001235761A1/en not_active Abandoned
- 2001-02-23 US US09/792,439 patent/US20020111303A1/en not_active Abandoned
- 2001-02-23 US US09/792,440 patent/US20030017456A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
GB0004576D0 (en) | 2000-04-19 |
WO2001063290A1 (en) | 2001-08-30 |
DE60113968T2 (en) | 2006-06-22 |
ES2249410T3 (en) | 2006-04-01 |
US20020111303A1 (en) | 2002-08-15 |
EP1257827A1 (en) | 2002-11-20 |
EP1259814A1 (en) | 2002-11-27 |
ATE306668T1 (en) | 2005-10-15 |
AU2001233917A1 (en) | 2001-09-03 |
EP1259814B1 (en) | 2005-10-12 |
DE60113968D1 (en) | 2006-02-23 |
WO2001063288A1 (en) | 2001-08-30 |
AU2001235761A1 (en) | 2001-09-03 |
WO2001063289A1 (en) | 2001-08-30 |
US20030017456A1 (en) | 2003-01-23 |
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