AU2001227755A1 - Inhibitors of prenyl-protein transferase - Google Patents

Inhibitors of prenyl-protein transferase

Info

Publication number
AU2001227755A1
AU2001227755A1 AU2001227755A AU2775501A AU2001227755A1 AU 2001227755 A1 AU2001227755 A1 AU 2001227755A1 AU 2001227755 A AU2001227755 A AU 2001227755A AU 2775501 A AU2775501 A AU 2775501A AU 2001227755 A1 AU2001227755 A1 AU 2001227755A1
Authority
AU
Australia
Prior art keywords
prenyl
inhibitors
protein transferase
transferase
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001227755A
Inventor
S. Jane Desolms
Suzanne C. Mactough
Anthony W. Shaw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU2001227755A1 publication Critical patent/AU2001227755A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D515/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D515/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D515/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
AU2001227755A 2000-01-12 2001-01-09 Inhibitors of prenyl-protein transferase Abandoned AU2001227755A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17570800P 2000-01-12 2000-01-12
US60175708 2000-01-12
PCT/US2001/000632 WO2001051125A1 (en) 2000-01-12 2001-01-09 Inhibitors of prenyl-protein transferase

Publications (1)

Publication Number Publication Date
AU2001227755A1 true AU2001227755A1 (en) 2001-07-24

Family

ID=22641313

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001227755A Abandoned AU2001227755A1 (en) 2000-01-12 2001-01-09 Inhibitors of prenyl-protein transferase

Country Status (3)

Country Link
US (1) US6413964B1 (en)
AU (1) AU2001227755A1 (en)
WO (1) WO2001051125A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004111077A1 (en) 2003-06-18 2004-12-23 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor
US8921533B2 (en) 2011-07-25 2014-12-30 Chromatin Technologies Glycosylated valproic acid analogs and uses thereof
MA39823A (en) * 2014-04-03 2018-01-09 Janssen Pharmaceutica Nv MACROCYCLIC PYRIDINE DERIVATIVES
CN109053525B (en) * 2018-09-25 2020-05-05 成都福柯斯医药技术有限公司 Preparation method of (R) -2- (2-substituted-5-fluorobenzene) pyrrolidine

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995000497A1 (en) 1993-06-18 1995-01-05 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
WO1995008542A1 (en) 1993-09-22 1995-03-30 Kyowa Hakko Kogyo Co., Ltd. Farnesyltransferase inhibitor
US5856326A (en) 1995-03-29 1999-01-05 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5756528A (en) 1995-06-06 1998-05-26 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5885995A (en) 1996-04-03 1999-03-23 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5919785A (en) 1996-04-03 1999-07-06 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5859012A (en) 1996-04-03 1999-01-12 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
AU707139B2 (en) 1996-04-03 1999-07-01 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
EP1014984A1 (en) 1997-08-27 2000-07-05 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
CA2306312A1 (en) 1997-10-17 1999-04-29 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
JP2002519427A (en) * 1998-07-02 2002-07-02 メルク エンド カムパニー インコーポレーテッド Prenyl protein transferase inhibitors
WO2000001382A1 (en) 1998-07-02 2000-01-13 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
CA2336475A1 (en) 1998-07-02 2000-01-13 Christopher J. Dinsmore Inhibitors of prenyl-protein transferase

Also Published As

Publication number Publication date
US6413964B1 (en) 2002-07-02
WO2001051125A1 (en) 2001-07-19

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