AU2000275433A1 - Process for the preparation of alkyl n-alkylanthranilate - Google Patents

Process for the preparation of alkyl n-alkylanthranilate

Info

Publication number
AU2000275433A1
AU2000275433A1 AU2000275433A AU7543300A AU2000275433A1 AU 2000275433 A1 AU2000275433 A1 AU 2000275433A1 AU 2000275433 A AU2000275433 A AU 2000275433A AU 7543300 A AU7543300 A AU 7543300A AU 2000275433 A1 AU2000275433 A1 AU 2000275433A1
Authority
AU
Australia
Prior art keywords
alkylanthranilate
alkyl
preparation
methylanthranilate
purity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2000275433A
Inventor
Carsten Berg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prom Ltd
Original Assignee
Prom Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prom Ltd filed Critical Prom Ltd
Publication of AU2000275433A1 publication Critical patent/AU2000275433A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

This invention is directed to a process of preparing alkyl N-alkylanthranilate, specially Methyl N-methylanthranilate, represented by Formula (I), in a one pot synthesis, using available and cheap commercial chemicals such as Isatoic anhydride, solid sodium hydroxide, dimethyl sulfate and methanol. Purity of the crude product is about 97% and yield 85%.
AU2000275433A 2000-10-04 2000-10-04 Process for the preparation of alkyl n-alkylanthranilate Abandoned AU2000275433A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB2000/003808 WO2002028818A1 (en) 2000-10-04 2000-10-04 Process for the preparation of alkyl n-alkylanthranilate

Publications (1)

Publication Number Publication Date
AU2000275433A1 true AU2000275433A1 (en) 2002-04-15

Family

ID=9885910

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2000275433A Abandoned AU2000275433A1 (en) 2000-10-04 2000-10-04 Process for the preparation of alkyl n-alkylanthranilate

Country Status (6)

Country Link
US (1) US7368592B1 (en)
EP (1) EP1322594B1 (en)
AT (1) ATE297376T1 (en)
AU (1) AU2000275433A1 (en)
DE (1) DE60020749T2 (en)
WO (1) WO2002028818A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013544819A (en) 2010-11-28 2013-12-19 マピ ファーマ リミテッド Intermediate compounds and processes for the preparation of quinoline derivatives such as laquinimod sodium

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2967128A (en) 1957-06-06 1961-01-03 S B Penick And Company Inc Bird repellent
GB1549297A (en) 1977-07-11 1979-08-01 Ici Ltd Anthranilic esters
IN146359B (en) 1977-07-26 1979-05-05 Council Scient Ind Res
US4633009A (en) 1985-06-18 1986-12-30 Frizsche Dodge & Olcott Inc. Synthesis of methyl N-methylanthranilate
GB2236318A (en) 1989-09-26 1991-04-03 Nitrokemia Ipartelepek Process for preparing pure N-methyl-anthranilic acid methylester

Also Published As

Publication number Publication date
ATE297376T1 (en) 2005-06-15
EP1322594B1 (en) 2005-06-08
EP1322594A1 (en) 2003-07-02
DE60020749D1 (en) 2005-07-14
DE60020749T2 (en) 2006-05-04
US7368592B1 (en) 2008-05-06
WO2002028818A1 (en) 2002-04-11

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