AU1926899A - Exploiting genomics in the search for new drugs - Google Patents

Exploiting genomics in the search for new drugs

Info

Publication number
AU1926899A
AU1926899A AU19268/99A AU1926899A AU1926899A AU 1926899 A AU1926899 A AU 1926899A AU 19268/99 A AU19268/99 A AU 19268/99A AU 1926899 A AU1926899 A AU 1926899A AU 1926899 A AU1926899 A AU 1926899A
Authority
AU
Australia
Prior art keywords
search
new drugs
genomics
exploiting
effects
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU19268/99A
Inventor
Ming Hsui Ho
David J. Lockhart
Lisa Wodicka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affymetrix Inc
Original Assignee
Affymetrix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affymetrix Inc filed Critical Affymetrix Inc
Publication of AU1926899A publication Critical patent/AU1926899A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Abstract

The cellular effects of potentially therapeutic compounds are characterized in mammalian cells and yeast. In the latter case the effects can be characterized on a genome-wide scale by monitoring changes in messenger RNA levels in treated cells with high-density oligonucleotide probe arrays.
AU19268/99A 1997-12-19 1998-12-18 Exploiting genomics in the search for new drugs Abandoned AU1926899A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6828997P 1997-12-19 1997-12-19
US60068289 1997-12-19
PCT/US1998/026925 WO1999032660A1 (en) 1997-12-19 1998-12-18 Exploiting genomics in the search for new drugs

Publications (1)

Publication Number Publication Date
AU1926899A true AU1926899A (en) 1999-07-12

Family

ID=22081628

Family Applications (1)

Application Number Title Priority Date Filing Date
AU19268/99A Abandoned AU1926899A (en) 1997-12-19 1998-12-18 Exploiting genomics in the search for new drugs

Country Status (6)

Country Link
US (3) US6333155B1 (en)
EP (1) EP1040204B1 (en)
AT (1) ATE260989T1 (en)
AU (1) AU1926899A (en)
DE (1) DE69822206T2 (en)
WO (1) WO1999032660A1 (en)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143557A (en) * 1995-06-07 2000-11-07 Life Technologies, Inc. Recombination cloning using engineered recombination sites
US6720140B1 (en) 1995-06-07 2004-04-13 Invitrogen Corporation Recombinational cloning using engineered recombination sites
US6165709A (en) 1997-02-28 2000-12-26 Fred Hutchinson Cancer Research Center Methods for drug target screening
US20030124555A1 (en) * 2001-05-21 2003-07-03 Invitrogen Corporation Compositions and methods for use in isolation of nucleic acid molecules
US7351578B2 (en) 1999-12-10 2008-04-01 Invitrogen Corp. Use of multiple recombination sites with unique specificity in recombinational cloning
CA2307016A1 (en) * 1997-10-24 1999-05-06 Life Technologies, Inc. Recombinational cloning using nucleic acids having recombination sites
US6593084B2 (en) * 1998-10-13 2003-07-15 Robert E. Bird Carcinogen assay
AU774643B2 (en) 1999-03-02 2004-07-01 Invitrogen Corporation Compositions and methods for use in recombinational cloning of nucleic acids
US7244559B2 (en) * 1999-09-16 2007-07-17 454 Life Sciences Corporation Method of sequencing a nucleic acid
AU1465801A (en) * 1999-11-03 2001-05-14 Oncotech, Inc. Methods for cancer prognosis and diagnosis
ATE391789T1 (en) * 1999-12-10 2008-04-15 Invitrogen Corp USE OF A VARIETY OF RECOMBINATION SITE WITH UNIQUE SPECIFICITY IN RECOMBINATORY CLONING
US8288128B2 (en) 2004-11-18 2012-10-16 Eppendorf Array Technologies S.A. Real-time quantification of multiple targets on a micro-array
US7829313B2 (en) 2000-03-24 2010-11-09 Eppendorf Array Technologies Identification and quantification of a plurality of biological (micro)organisms or their components
AU2001251086A1 (en) * 2000-03-31 2001-10-15 Sir Mortimer B. Davis Jewish General Hospital Microchip arrays of regulatory genes
EP1268858A1 (en) * 2000-03-31 2003-01-02 Memorec Stoffel GmbH Medizinisch-Molekulare Entwicklung Use of particles which have signal-emitting characteristics and at least one group with an affinity for marked nucleic acids
US7244560B2 (en) * 2000-05-21 2007-07-17 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
US6743583B2 (en) * 2000-07-14 2004-06-01 The Board Of Trustees Of The Leland Stanford Junior University Identification of drugs and drug targets by detection of the stress response
WO2002006834A2 (en) * 2000-07-19 2002-01-24 Pointilliste, Inc. Nested sorting and high throughput screening
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
US6998234B2 (en) * 2000-11-03 2006-02-14 Oncotech, Inc. Methods for cancer prognosis and diagnosis relating to tumor vascular endothelial cells
WO2002095000A2 (en) 2001-05-22 2002-11-28 Gene Logic, Inc. Molecular toxicology modeling
US20050009022A1 (en) * 2001-07-06 2005-01-13 Weiner Michael P. Method for isolation of independent, parallel chemical micro-reactions using a porous filter
US7447594B2 (en) 2001-07-10 2008-11-04 Ocimum Biosolutions, Inc. Molecular cardiotoxicology modeling
US20030054396A1 (en) * 2001-09-07 2003-03-20 Weiner Michael P. Enzymatic light amplification
US6902921B2 (en) * 2001-10-30 2005-06-07 454 Corporation Sulfurylase-luciferase fusion proteins and thermostable sulfurylase
US6956114B2 (en) 2001-10-30 2005-10-18 '454 Corporation Sulfurylase-luciferase fusion proteins and thermostable sulfurylase
US20050124022A1 (en) * 2001-10-30 2005-06-09 Maithreyan Srinivasan Novel sulfurylase-luciferase fusion proteins and thermostable sulfurylase
EP1474504A2 (en) * 2002-01-24 2004-11-10 Pointilliste, Inc. Use of collections of binding sites for sample profiling and other applications
US20030195431A1 (en) * 2002-04-10 2003-10-16 Sukhatme Vikas P. Observation of effects of body fluids on indicator cells for disease diagnosis
US20040053319A1 (en) * 2002-09-17 2004-03-18 Mcwilliams Diana R. Isolation of genetic molecules from a complex biological constrauct for use in genetic expression analysis
US7364846B2 (en) * 2002-10-11 2008-04-29 Molecular Devices Corporation Gene expression profiling from FFPE samples
US7781163B2 (en) * 2003-01-08 2010-08-24 Lesley Davenport G-quadruplex binding assays and compounds therefor
DE602004024034D1 (en) 2003-01-29 2009-12-24 454 Corp NUCLEIC ACID AMPLIFICATION BASED ON KINGGEL EMULSION
US7575865B2 (en) 2003-01-29 2009-08-18 454 Life Sciences Corporation Methods of amplifying and sequencing nucleic acids
WO2004079000A1 (en) * 2003-03-07 2004-09-16 National Research Council Of Canada The determination of function of mammalian proteins by analysis of global gene expression profiles
EP1616026A1 (en) 2003-04-14 2006-01-18 Novartis AG Gene expression associated with osteoblast differentiation
US20050009059A1 (en) * 2003-05-07 2005-01-13 Affymetrix, Inc. Analysis of methylation status using oligonucleotide arrays
JP2006526990A (en) 2003-06-06 2006-11-30 アーバージェン リミテッド ライアビリティ カンパニー Compositions and methods for modulating plant cell polysaccharides
US7507875B2 (en) 2003-06-06 2009-03-24 Arborgen, Llc Transcription factors
US20050064462A1 (en) * 2003-06-17 2005-03-24 Bernd Stein Methods, compositions, and kits for predicting the effect of compounds on hot flash symptoms
US20050064472A1 (en) * 2003-07-23 2005-03-24 Affymetrix, Inc. Methods of monitoring gene expression
CA2543091C (en) * 2003-10-24 2013-09-03 John Austin Apparatus and method for dispensing fluid, semi-solid and solid samples
ATE469984T1 (en) 2003-12-01 2010-06-15 Life Technologies Corp NUCLEIC ACID MOLECULES CONTAINING RECOMBINATION SITE AND METHOD FOR USE THEREOF
AR047574A1 (en) 2003-12-30 2006-01-25 Arborgen Llc 2 Genesis Res 1 CELL CYCLE GENES AND RELATED USE METHODS
US7598080B2 (en) 2004-08-20 2009-10-06 Carl Deirmengian Diagnostic assay for source of inflammation
FI20041204A0 (en) 2004-09-16 2004-09-16 Riikka Lund Methods for the utilization of new target genes associated with immune-mediated diseases
US7799906B1 (en) 2004-09-22 2010-09-21 Arborgen, Llc Compositions and methods for modulating lignin of a plant
EP2302072B1 (en) 2004-11-18 2012-03-14 Eppendorf Array Technologies S.A. Real time-PCR of targets on a micro-array
US8178291B2 (en) 2005-02-18 2012-05-15 Monogram Biosciences, Inc. Methods and compositions for determining hypersusceptibility of HIV-1 to non-nucleoside reverse transcriptase inhibitors
EP1856298B1 (en) 2005-02-18 2017-09-27 Monogram BioSciences, Inc. Methods and compositions for determining anti-hiv drug susceptibility and replication capacity of hiv
US20070072175A1 (en) * 2005-05-13 2007-03-29 Biogen Idec Ma Inc. Nucleotide array containing polynucleotide probes complementary to, or fragments of, cynomolgus monkey genes and the use thereof
EP1896618A4 (en) 2005-05-27 2009-12-30 Monogram Biosciences Inc Methods and compositions for determining resistance of hiv-1 to protease inhibitors
US9506121B2 (en) 2005-06-06 2016-11-29 Monogram Biosciences, Inc. Methods for determining resistance or susceptibility to HIV entry inhibitors
WO2006133267A2 (en) 2005-06-06 2006-12-14 Monogram Biosciences, Inc. Methods and compositions for determining altered susceptibility of hiv-1 to anti-hiv drugs
EP1736780A1 (en) 2005-06-24 2006-12-27 Eppendorf Array Technologies S.A. Method and means for detecting and/or quantifying hierarchical molecular change of a cell in response to an external stimulus
WO2007028161A2 (en) * 2005-09-02 2007-03-08 The University Of Toledo Methods and compositions for identifying biomarkers useful in diagnosis and/or treatment of biological states
EP1762628B1 (en) 2005-09-13 2008-03-12 Eppendorf Array Technologies SA Detection method of homologous sequences differing by one base on a microarray
US20070092903A1 (en) * 2005-10-24 2007-04-26 Fulmer-Smentek Stephanie B One-color microarray analysis methods, reagents and kits
AU2005239672B2 (en) * 2005-11-30 2009-06-11 Canon Kabushiki Kaisha Sortable collection browser
WO2007098065A2 (en) * 2006-02-17 2007-08-30 The United States Of America As Represented By The Department Of Veterans Affairs Human sodium channel isoforms
JP5301424B2 (en) * 2006-03-15 2013-09-25 ブライアン アール． ソーパー， Methods for screening and mapping phenotypic and genotypic variations in cells
US7901882B2 (en) 2006-03-31 2011-03-08 Affymetrix, Inc. Analysis of methylation using nucleic acid arrays
US8257929B2 (en) 2006-10-20 2012-09-04 University Of Miami Gene expression profiling of Parkinson's Disease
EP1935496A1 (en) 2006-12-22 2008-06-25 Eppendorf Array Technologies SA Device and/or method for the detection of amplified nucleotides sequences on micro-arrays
WO2008106115A2 (en) 2007-02-26 2008-09-04 Monogram Biosciences, Inc. Compositions and methods for determining whether a subject would benefit from co-receptor inhibitor therapy
EP1961825A1 (en) 2007-02-26 2008-08-27 INSERM (Institut National de la Santé et de la Recherche Medicale) Method for predicting the occurrence of metastasis in breast cancer patients
EP2107125A1 (en) 2008-03-31 2009-10-07 Eppendorf Array Technologies SA (EAT) Real-time PCR of targets on a micro-array
US9782565B2 (en) 2008-10-01 2017-10-10 Covidien Lp Endoscopic ultrasound-guided biliary access system
US9186128B2 (en) 2008-10-01 2015-11-17 Covidien Lp Needle biopsy device
US11298113B2 (en) 2008-10-01 2022-04-12 Covidien Lp Device for needle biopsy with integrated needle protection
US8968210B2 (en) 2008-10-01 2015-03-03 Covidien LLP Device for needle biopsy with integrated needle protection
US20110190662A1 (en) * 2008-10-01 2011-08-04 Beacon Endoscopic Corporation Rapid exchange fna biopsy device with diagnostic and therapeutic capabilities
US9332973B2 (en) 2008-10-01 2016-05-10 Covidien Lp Needle biopsy device with exchangeable needle and integrated needle protection
CN107050401A (en) 2009-12-29 2017-08-18 希尔氏宠物营养品公司 The composition for including ginger for improving or preventing the inflammatory patient's condition
FI20105166A0 (en) 2010-02-19 2010-02-19 Suomen Punainen Risti Veripalv A method for detecting a differentiation state of a stem cell population
EP2369325A1 (en) 2010-03-12 2011-09-28 Eppendorf Ag Array analysis for online detection
WO2013043878A2 (en) 2011-09-20 2013-03-28 The George Washington University Alternative splicing variants of genes associated with prostate cancer risk and survival
US9988687B2 (en) 2011-09-20 2018-06-05 The George Washington Univeristy Companion diagnostics for cancer and screening methods to identify companion diagnostics for cancer based on splicing variants
EP3418397B1 (en) 2012-01-24 2020-10-07 CD Diagnostics, Inc. System for detecting infection in synovial fluid
EP2664619B1 (en) * 2012-05-16 2017-07-12 Manros Therapeutics Purine derivatives as tools for screening anti-Alzheimer compounds
US9671405B2 (en) 2012-09-19 2017-06-06 Cornell University Identifying taxane sensitivity in prostate cancer patients
EP3736570A1 (en) 2019-05-09 2020-11-11 Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León Method for the diagnosis, sub-classification and prognosis of acute kidney injury by detecting cct7

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8810400D0 (en) 1988-05-03 1988-06-08 Southern E Analysing polynucleotide sequences
US5700637A (en) 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
US6040138A (en) * 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
PT725682E (en) * 1993-10-28 2002-09-30 Houston Advanced Res Ct POROSO MICROFABRICATED DRAIN DEVICE
JP2002515738A (en) 1996-01-23 2002-05-28 アフィメトリックス，インコーポレイティド Nucleic acid analysis
JP2000504672A (en) 1996-02-09 2000-04-18 フィテラ シンビオン エイピーエス Balanol analogues
US5866702A (en) 1996-08-02 1999-02-02 Cv Therapeutics, Incorporation Purine inhibitors of cyclin dependent kinase 2
US5965352A (en) 1998-05-08 1999-10-12 Rosetta Inpharmatics, Inc. Methods for identifying pathways of drug action

Also Published As

Publication number Publication date
DE69822206T2 (en) 2005-02-17
EP1040204A1 (en) 2000-10-04
EP1040204B1 (en) 2004-03-03
US20030180774A1 (en) 2003-09-25
DE69822206D1 (en) 2004-04-08
US20010055771A1 (en) 2001-12-27
US6524800B2 (en) 2003-02-25
ATE260989T1 (en) 2004-03-15
WO1999032660A9 (en) 1999-09-23
WO1999032660A1 (en) 1999-07-01
US6333155B1 (en) 2001-12-25

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Legal Events

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MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase