AU1535002A - Methods for detecting modulators of ion channels using thallium (i) sensitive assays - Google Patents
Methods for detecting modulators of ion channels using thallium (i) sensitive assaysInfo
- Publication number
- AU1535002A AU1535002A AU1535002A AU1535002A AU1535002A AU 1535002 A AU1535002 A AU 1535002A AU 1535002 A AU1535002 A AU 1535002A AU 1535002 A AU1535002 A AU 1535002A AU 1535002 A AU1535002 A AU 1535002A
- Authority
- AU
- Australia
- Prior art keywords
- thallium
- methods
- ion channels
- sensitive assays
- detecting modulators
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000004310 Ion Channels Human genes 0.000 title 1
- 238000003556 assay Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- ZLUSCZLCHQSJRU-UHFFFAOYSA-N thallium(1+) Chemical compound [Tl+] ZLUSCZLCHQSJRU-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24052300P | 2000-10-13 | 2000-10-13 | |
PCT/US2001/032132 WO2002031508A1 (en) | 2000-10-13 | 2001-10-12 | Methods for detecting modulators of ion channels using thallium (i) sensitive assays |
Publications (1)
Publication Number | Publication Date |
---|---|
AU1535002A true AU1535002A (en) | 2002-04-22 |
Family
ID=22906876
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU1535002A Pending AU1535002A (en) | 2000-10-13 | 2001-10-12 | Methods for detecting modulators of ion channels using thallium (i) sensitive assays |
AU2002215350A Ceased AU2002215350B2 (en) | 2000-10-13 | 2001-10-12 | Methods for detecting modulators of ion channels using thallium (I) sensitive assays |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002215350A Ceased AU2002215350B2 (en) | 2000-10-13 | 2001-10-12 | Methods for detecting modulators of ion channels using thallium (I) sensitive assays |
Country Status (8)
Country | Link |
---|---|
US (2) | US20020168625A1 (en) |
EP (1) | EP1327150A1 (en) |
JP (2) | JP2004530100A (en) |
AU (2) | AU1535002A (en) |
CA (1) | CA2425806A1 (en) |
IL (1) | IL155317A0 (en) |
MX (1) | MXPA03003223A (en) |
WO (1) | WO2002031508A1 (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10078087B2 (en) | 2001-05-01 | 2018-09-18 | Senomyx, Inc. | Assays and enhancers of the human delta ENaC sodium channel |
US6770484B2 (en) * | 2001-11-29 | 2004-08-03 | Dong C. Liang | Using flame and graphite furnace atomic absorption spectrometry for analysis of sodium channel activity |
DE10243599A1 (en) * | 2002-09-19 | 2004-04-01 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Measuring device and method for a screening of cells immobilized on electrodes |
EP1644738A2 (en) | 2003-07-10 | 2006-04-12 | Senomyx Inc. | IMPROVED ELECTROPHYSIOLOGICAL ASSAYS USING OOCYTES THAT EXPRESS HUMAN ENaC AND THE USE OF PHENAMIL TO IMPROVE THE EFFECT OF ENaC ENHANCERS IN ASSAYS USING MEMBRANE POTENTIAL REPORTING DYES |
WO2005069008A1 (en) * | 2004-01-15 | 2005-07-28 | Evotec Ag | Method for examining the activity of ion channels |
CA2571540A1 (en) * | 2004-06-23 | 2006-01-26 | Ortho-Mcneil Pharmaceutical, Inc. | Methods for measuring chloride channel conductivity |
US20070092970A1 (en) * | 2005-10-25 | 2007-04-26 | Liang Dong C | High-throughput screening assay for Na, K-ATPase using atomic absorption spectroscopy |
DE102007011913A1 (en) * | 2007-03-13 | 2008-10-23 | Sanofi-Aventis | Fluorescence-based Assay to Detect Compounds for Modulating the Sodium Calcium Exchange (NCX) in the "Forward Mode" |
DE102007012029A1 (en) * | 2007-03-13 | 2008-09-18 | Grünenthal GmbH | Method for identifying the agonistic activity of a target compound on a potassium channel |
US8318502B2 (en) * | 2007-06-05 | 2012-11-27 | Life Technologies Corporation | Long wavelength fluorogenic intracellular ion indicators that are well retained in the cytosol |
WO2009002423A2 (en) | 2007-06-21 | 2008-12-31 | Schering Corporation | Polycyclic guanine derivatives and use thereof |
JP2011501155A (en) * | 2007-10-15 | 2011-01-06 | ライフ テクノロジーズ コーポレーション | Compositions and methods for measuring thallium inflow and outflow |
EP2103944A1 (en) * | 2008-03-20 | 2009-09-23 | sanofi-aventis | Fluorescence based assay to detect sodium/calcium exchanger "forward mode" modulating compounds |
US9134323B2 (en) | 2009-12-01 | 2015-09-15 | The Rockefeller University | Antibody that specifically binds to an epitope in the tureet region of a human Kir channel |
US9579106B2 (en) | 2010-03-31 | 2017-02-28 | New York Society For The Relief Of The Ruptured And Crippled, Maintaining The Hospital For Special Surgery | Shoulder arthroplasty instrumentation |
US9103791B1 (en) | 2012-09-26 | 2015-08-11 | Vanderbilt University | Thallium fluorescent ion indicator and assay |
EP2712702B1 (en) * | 2012-10-01 | 2014-12-03 | Supfina Grieshaber GmbH & Co. KG | Belt finishing device, belt finishing system and method for producing a belt finishing device |
CN109690317B (en) * | 2016-08-17 | 2023-05-02 | 生命科技股份有限公司 | Compositions and methods for measuring ion channel activity in cells |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5670113A (en) * | 1991-12-20 | 1997-09-23 | Sibia Neurosciences, Inc. | Automated analysis equipment and assay method for detecting cell surface protein and/or cytoplasmic receptor function using same |
WO1994019464A2 (en) * | 1993-02-19 | 1994-09-01 | The Upjohn Company | Human dna sequence encoding a kidney atp-dependent potassium channel |
US5985214A (en) * | 1997-05-16 | 1999-11-16 | Aurora Biosciences Corporation | Systems and methods for rapidly identifying useful chemicals in liquid samples |
GB9925799D0 (en) * | 1999-11-02 | 1999-12-29 | Cambridge Drug Discovery Ltd | Ion channel permeability |
-
2001
- 2001-10-12 AU AU1535002A patent/AU1535002A/en active Pending
- 2001-10-12 AU AU2002215350A patent/AU2002215350B2/en not_active Ceased
- 2001-10-12 MX MXPA03003223A patent/MXPA03003223A/en not_active Application Discontinuation
- 2001-10-12 IL IL15531701A patent/IL155317A0/en unknown
- 2001-10-12 WO PCT/US2001/032132 patent/WO2002031508A1/en active Application Filing
- 2001-10-12 US US09/975,891 patent/US20020168625A1/en not_active Abandoned
- 2001-10-12 CA CA002425806A patent/CA2425806A1/en not_active Abandoned
- 2001-10-12 EP EP01983962A patent/EP1327150A1/en not_active Withdrawn
- 2001-10-12 JP JP2002534842A patent/JP2004530100A/en not_active Withdrawn
-
2007
- 2007-04-04 US US11/696,242 patent/US20070172815A1/en not_active Abandoned
-
2008
- 2008-07-24 JP JP2008191135A patent/JP2008264004A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2002215350B2 (en) | 2006-12-07 |
JP2004530100A (en) | 2004-09-30 |
WO2002031508A1 (en) | 2002-04-18 |
EP1327150A1 (en) | 2003-07-16 |
US20070172815A1 (en) | 2007-07-26 |
IL155317A0 (en) | 2003-11-23 |
JP2008264004A (en) | 2008-11-06 |
MXPA03003223A (en) | 2003-09-10 |
CA2425806A1 (en) | 2002-04-18 |
US20020168625A1 (en) | 2002-11-14 |
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