AU1438592A - Cd4-gamma1 and cd4-igg1 chimeras - Google Patents

Cd4-gamma1 and cd4-igg1 chimeras

Info

Publication number
AU1438592A
AU1438592A AU14385/92A AU1438592A AU1438592A AU 1438592 A AU1438592 A AU 1438592A AU 14385/92 A AU14385/92 A AU 14385/92A AU 1438592 A AU1438592 A AU 1438592A AU 1438592 A AU1438592 A AU 1438592A
Authority
AU
Australia
Prior art keywords
gamma1
chimeras
igg1
igg1 chimeras
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU14385/92A
Inventor
Gary A Beaudry
Paul J. Maddon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Progenics Pharmaceuticals Inc
Original Assignee
Progenics Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Progenics Pharmaceuticals Inc filed Critical Progenics Pharmaceuticals Inc
Publication of AU1438592A publication Critical patent/AU1438592A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
AU14385/92A 1991-02-08 1992-02-10 Cd4-gamma1 and cd4-igg1 chimeras Abandoned AU1438592A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65420591A 1991-02-08 1991-02-08
US654205 1991-02-08

Publications (1)

Publication Number Publication Date
AU1438592A true AU1438592A (en) 1992-09-07

Family

ID=24623890

Family Applications (1)

Application Number Title Priority Date Filing Date
AU14385/92A Abandoned AU1438592A (en) 1991-02-08 1992-02-10 Cd4-gamma1 and cd4-igg1 chimeras

Country Status (2)

Country Link
AU (1) AU1438592A (en)
WO (1) WO1992013559A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3670276B2 (en) 1991-02-08 2005-07-13 プロゲニクス・ファーマスーティカルズ、インコーポレイテッド CD4-Gamma-2 chimera and CD4-IgG2 chimera
US7070991B2 (en) 1991-02-08 2006-07-04 Progenics Pharmaceuticals, Inc. Cells expressing a CD4-IgG2 chimeric heterotetramer
JPH08503125A (en) * 1992-08-07 1996-04-09 プロジェニクス・ファーマスーティカルス・インコーポレーテッド CD4-gamma2 and CD4-IgG2 immunoconjugates complexed with non-peptidyl components and uses thereof
US5817767A (en) * 1993-02-24 1998-10-06 Progenics Pharmaceuticals, Inc. Synergistic composition of CD4-based protein and anti-HIV-1 antibody, and methods of using same
US20030040467A1 (en) 1998-06-15 2003-02-27 Mary Ann Pelleymounter Ig/ob fusions and uses thereof.
US6936439B2 (en) 1995-11-22 2005-08-30 Amgen Inc. OB fusion protein compositions and methods
WO1998032771A1 (en) * 1997-01-29 1998-07-30 Toray Industries, Inc. Chimeric proteins, heterodimer complexes thereof and substitute for platelet
EP1446158B1 (en) * 2001-10-25 2010-07-07 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Efficient inhibition of hiv-1 viral entry through a novel fusion protein including cd4
US20040214285A1 (en) * 2003-02-10 2004-10-28 Glass David J. HIV-specific fusion proteins and therapeutic and diagnostic methods for use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3134874B2 (en) * 1986-08-21 2001-02-13 ザ・トラステイーズ・オブ・コロンビア・ユニヴアーシテイ・イン・ザ・シテイ・オブ・ニユー・ヨーク Use of DNA encoding T cell surface protein T4 and T4 fragment for AIDS treatment
KR890701605A (en) * 1987-07-04 1989-12-21 원본미기재 DNA sequence, recombinant DNA molecule and method for producing soluble T4 protein
PT88641B (en) * 1987-10-02 1993-04-30 Genentech Inc METHOD FOR PREPARING A VARIETY OF ADHESION
IL87902A0 (en) * 1987-10-08 1989-03-31 Dana Farber Cancer Inst Inc Soluble human cd4 fragments and applications thereof

Also Published As

Publication number Publication date
WO1992013559A1 (en) 1992-08-20

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