ATE98235T1 - 2-thiazolidinon-derivate und diese enthaltende pharmazeutische praeparate, verfahren zu deren herstellung und deren verwendung. - Google Patents
2-thiazolidinon-derivate und diese enthaltende pharmazeutische praeparate, verfahren zu deren herstellung und deren verwendung.Info
- Publication number
- ATE98235T1 ATE98235T1 AT88120908T AT88120908T ATE98235T1 AT E98235 T1 ATE98235 T1 AT E98235T1 AT 88120908 T AT88120908 T AT 88120908T AT 88120908 T AT88120908 T AT 88120908T AT E98235 T1 ATE98235 T1 AT E98235T1
- Authority
- AT
- Austria
- Prior art keywords
- manufacture
- processes
- pharmaceutical preparations
- preparations containing
- thiazolidinone derivatives
- Prior art date
Links
- SLYRGJDSFOCAAI-UHFFFAOYSA-N 1,3-thiazolidin-2-one Chemical class O=C1NCCS1 SLYRGJDSFOCAAI-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 208000007107 Stomach Ulcer Diseases 0.000 abstract 1
- 230000001120 cytoprotective effect Effects 0.000 abstract 1
- 208000000718 duodenal ulcer Diseases 0.000 abstract 1
- 230000027119 gastric acid secretion Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/14—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Silver Salt Photography Or Processing Solution Therefor (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU875632A HU198915B (en) | 1987-12-14 | 1987-12-14 | Process for producing new 2-thiazolidinone derivatives and pharmaceutical compositions containing them |
EP88120908A EP0320910B1 (de) | 1987-12-14 | 1988-12-14 | 2-Thiazolidinon-Derivate und diese enthaltende pharmazeutische Präparate, Verfahren zu deren Herstellung und deren Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE98235T1 true ATE98235T1 (de) | 1993-12-15 |
Family
ID=10970509
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT88120908T ATE98235T1 (de) | 1987-12-14 | 1988-12-14 | 2-thiazolidinon-derivate und diese enthaltende pharmazeutische praeparate, verfahren zu deren herstellung und deren verwendung. |
Country Status (13)
Country | Link |
---|---|
US (1) | US4937252A (de) |
EP (1) | EP0320910B1 (de) |
JP (1) | JPH02279A (de) |
KR (1) | KR920010179B1 (de) |
CN (1) | CN1019196B (de) |
AT (1) | ATE98235T1 (de) |
CA (1) | CA1332419C (de) |
DE (1) | DE3886185T2 (de) |
ES (1) | ES2049243T3 (de) |
HU (1) | HU198915B (de) |
LT (1) | LT2199B (de) |
LV (1) | LV5491A3 (de) |
SU (1) | SU1657062A3 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU205092B (en) * | 1989-11-24 | 1992-03-30 | Richter Gedeon Vegyeszet | Process for producing new thiazolidinone derivatives and pharmaceutical compositions comprising same |
HU210789B (en) * | 1992-12-23 | 1995-07-28 | Richter Gedeon Vegyeszet | Process for preparing new thiazolidinone derivatives and pharmaceutical preparations containing them |
CN103351358B (zh) * | 2013-07-03 | 2015-05-27 | 北京化工大学 | 一种5-取代2-噻唑烷酮的制备方法 |
RU2643669C1 (ru) * | 2017-04-03 | 2018-02-05 | Федеральное государственное бюджетное учреждение науки Новосибирский институт органической химии им. Н.Н. Ворожцова Сибирского отделения Российской академии наук (НИОХ СО РАН) | 3-[3-(морфолин-4-ил)пропил]-2-[(2,2,3-триметилциклопент-3-ен-1-ил)метил]-1,3-тиазолидин-4-он, обладающий противоязвенной и противовоспалительной активностью |
CN115093378B (zh) * | 2022-07-21 | 2024-01-26 | 三门峡奥科科技有限公司 | 一种2-噻唑烷酮的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3066919A (en) * | 1958-11-12 | 1962-12-04 | Waimer Eberhard | Concrete mixer |
JPS53127466A (en) * | 1977-04-13 | 1978-11-07 | Asahi Chem Ind Co Ltd | Thiocarbamate type heterocyclic compounds and its preparation |
US4664694A (en) * | 1985-04-24 | 1987-05-12 | Uniroyal Chemical Company, Inc. | Substituted thiazolidinones useful as plant growth regulators |
-
1987
- 1987-12-14 HU HU875632A patent/HU198915B/hu not_active IP Right Cessation
-
1988
- 1988-12-07 CA CA000585257A patent/CA1332419C/en not_active Expired - Fee Related
- 1988-12-13 CN CN88108626A patent/CN1019196B/zh not_active Expired
- 1988-12-13 JP JP63314813A patent/JPH02279A/ja active Pending
- 1988-12-13 US US07/283,809 patent/US4937252A/en not_active Expired - Fee Related
- 1988-12-14 EP EP88120908A patent/EP0320910B1/de not_active Expired - Lifetime
- 1988-12-14 DE DE88120908T patent/DE3886185T2/de not_active Expired - Fee Related
- 1988-12-14 ES ES88120908T patent/ES2049243T3/es not_active Expired - Lifetime
- 1988-12-14 AT AT88120908T patent/ATE98235T1/de not_active IP Right Cessation
- 1988-12-14 SU SU884613151A patent/SU1657062A3/ru active
- 1988-12-14 KR KR1019880016674A patent/KR920010179B1/ko not_active IP Right Cessation
-
1993
- 1993-06-28 LV LV930678A patent/LV5491A3/xx unknown
- 1993-08-13 LT LTRP854A patent/LT2199B/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR920010179B1 (ko) | 1992-11-19 |
JPH02279A (ja) | 1990-01-05 |
US4937252A (en) | 1990-06-26 |
KR890009897A (ko) | 1989-08-04 |
CN1019196B (zh) | 1992-11-25 |
EP0320910B1 (de) | 1993-12-08 |
LV5491A3 (lv) | 1994-03-10 |
HU198915B (en) | 1989-12-28 |
CN1033625A (zh) | 1989-07-05 |
LT2199B (lt) | 1993-10-15 |
ES2049243T3 (es) | 1994-04-16 |
HUT49125A (en) | 1989-08-28 |
EP0320910A1 (de) | 1989-06-21 |
DE3886185D1 (de) | 1994-01-20 |
DE3886185T2 (de) | 1994-05-05 |
SU1657062A3 (ru) | 1991-06-15 |
CA1332419C (en) | 1994-10-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |