ATE9347T1 - Salze von endo-8-methyl-8-syn-alkyl-8- - Google Patents

Salze von endo-8-methyl-8-syn-alkyl-8-

Info

Publication number
ATE9347T1
ATE9347T1 AT81830096T AT81830096T ATE9347T1 AT E9347 T1 ATE9347 T1 AT E9347T1 AT 81830096 T AT81830096 T AT 81830096T AT 81830096 T AT81830096 T AT 81830096T AT E9347 T1 ATE9347 T1 AT E9347T1
Authority
AT
Austria
Prior art keywords
alkyl
syn
endo
methyl
salts
Prior art date
Application number
AT81830096T
Other languages
English (en)
Inventor
Virgilio Bernareggi
Fausto Bonifacio
Maurizio Fano
Roberto Margutti
Original Assignee
Valeas S.P.A. Industria Chimica E Farmaceutica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valeas S.P.A. Industria Chimica E Farmaceutica filed Critical Valeas S.P.A. Industria Chimica E Farmaceutica
Application granted granted Critical
Publication of ATE9347T1 publication Critical patent/ATE9347T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT81830096T 1980-06-18 1981-06-11 Salze von endo-8-methyl-8-syn-alkyl-8- ATE9347T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT22843/80A IT1140998B (it) 1980-06-18 1980-06-18 Sali di endo-8-metil-8-sin-alchil-8-azoniabiciclo aperta par. quadrata 3.2.1. chiusa par. quadrata-ottan-3-alchilcarbossilati, processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo
EP81830096A EP0042365B1 (de) 1980-06-18 1981-06-11 Salze von Endo-8-methyl-8-syn-alkyl-8-azoniabicyclo(3,2,1)-octan-3-alkylcarbonsäure, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE9347T1 true ATE9347T1 (de) 1984-09-15

Family

ID=11201066

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81830096T ATE9347T1 (de) 1980-06-18 1981-06-11 Salze von endo-8-methyl-8-syn-alkyl-8-

Country Status (9)

Country Link
US (1) US4411902A (de)
EP (1) EP0042365B1 (de)
JP (1) JPS5728086A (de)
AT (1) ATE9347T1 (de)
AU (1) AU547923B2 (de)
CA (1) CA1161040A (de)
DE (1) DE3165993D1 (de)
IT (1) IT1140998B (de)
ZA (1) ZA813786B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1194343B (it) * 1983-07-26 1988-09-14 Valeas Spa Sali di endo-8,8-dialchil-8-azoniabiciclo (3.2.1) ottan-6,7-esso-epossi-3-alchilcarbossilati,processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo
US4698217A (en) * 1985-02-26 1987-10-06 Mobil Oil Corporation Crystalline silicate ZSM-58 and process for its preparation using a methyltropinium cation
AT397962B (de) * 1985-12-27 1994-08-25 Madaus & Co Dr Verfahren zur herstellung von azoniaspironortropanolestern
US5770738A (en) * 1992-03-05 1998-06-23 Boehringer Ingelheim Kg Esters of bi- and tricyclic amino alcohols, their preparation and their use in pharmaceutical compositions
WO2001031236A2 (en) * 1999-10-28 2001-05-03 Isotech Of Illinois, Inc. Improved bearing isolator
US6706726B2 (en) * 2000-10-14 2004-03-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Anticholinergics which may be used as medicaments as well as processes for preparing them
TW200534855A (en) * 2004-01-13 2005-11-01 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
PE20060826A1 (es) * 2004-12-06 2006-10-08 Smithkline Beecham Corp Derivado oleofinico de 8-azoniabiciclo[3.2.1]octano y combinacion farmaceutica que lo comprende
RU2714135C1 (ru) * 2019-11-22 2020-02-12 Федеральное государственное бюджетное учреждение науки "Институт токсикологии Федерального медико-биологического агентства" Гидрохлорид (1-метилпиперидин-4-ил)-2-пропилпентаноата, обладающий холинолитической и противосудорожной активностью

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3170927A (en) * 1965-02-23 O chzoh
US2962499A (en) * 1957-07-03 1960-11-29 Endo Lab Certain esters of tropine and tropinium salts
US3145211A (en) * 1962-01-04 1964-08-18 Sterling Drug Inc Tropyl esters of alpha-cycloalkylalkanoic acids

Also Published As

Publication number Publication date
IT8022843A0 (it) 1980-06-18
IT1140998B (it) 1986-10-10
AU7195381A (en) 1981-12-24
DE3165993D1 (en) 1984-10-18
CA1161040A (en) 1984-01-24
US4411902A (en) 1983-10-25
JPS5728086A (en) 1982-02-15
AU547923B2 (en) 1985-11-14
JPH0335319B2 (de) 1991-05-27
EP0042365A1 (de) 1981-12-23
ZA813786B (en) 1982-07-28
EP0042365B1 (de) 1984-09-12

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee