ATE89566T1 - Molekuele mit mindestens einer peptidsequenz einer oder mehrerer epitopen eines p.falciparum- produzierten proteins in hepatozyten und zusammensetzungen davon. - Google Patents
Molekuele mit mindestens einer peptidsequenz einer oder mehrerer epitopen eines p.falciparum- produzierten proteins in hepatozyten und zusammensetzungen davon.Info
- Publication number
- ATE89566T1 ATE89566T1 AT88901854T AT88901854T ATE89566T1 AT E89566 T1 ATE89566 T1 AT E89566T1 AT 88901854 T AT88901854 T AT 88901854T AT 88901854 T AT88901854 T AT 88901854T AT E89566 T1 ATE89566 T1 AT E89566T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- gln
- glu
- falciparum
- hepatocytes
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 206010035500 Plasmodium falciparum infection Diseases 0.000 title 1
- 210000003494 hepatocyte Anatomy 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000011885 in vitro diagnostic (IVD) kits Methods 0.000 abstract 1
- 201000004792 malaria Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/20—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
- C07K16/205—Plasmodium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8701543A FR2610631B1 (fr) | 1987-02-09 | 1987-02-09 | Molecules comportant au moins une sequence peptidique porteuse d'un ou plusieurs, epitope caracteristique d'une proteine produite par p. falciparum dans les hepatocytes, et leurs utilisations, notamment pour le diagnostic du paludisme ou dans des compositions de vaccins contre le paludisme |
EP88901854A EP0343186B1 (de) | 1987-02-09 | 1988-02-09 | Moleküle mit mindestens einer peptidsequenz einer oder mehrerer epitopen eines p.falciparum-produzierten proteins in hepatozyten und zusammensetzungen davon |
PCT/FR1988/000074 WO1988005785A1 (fr) | 1987-02-09 | 1988-02-09 | Molecules comportant au moins une sequence peptidique porteuse d'un, ou plusieurs, epitopes caracteristiques d'une proteine produite par p. falciparum dans les hepatocytes et compositions les contenant |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE89566T1 true ATE89566T1 (de) | 1993-06-15 |
Family
ID=9347704
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT88901854T ATE89566T1 (de) | 1987-02-09 | 1988-02-09 | Molekuele mit mindestens einer peptidsequenz einer oder mehrerer epitopen eines p.falciparum- produzierten proteins in hepatozyten und zusammensetzungen davon. |
Country Status (8)
Country | Link |
---|---|
US (4) | US5599542A (de) |
EP (1) | EP0343186B1 (de) |
JP (1) | JP2729070B2 (de) |
AT (1) | ATE89566T1 (de) |
AU (1) | AU610571B2 (de) |
DE (1) | DE3881204T2 (de) |
FR (1) | FR2610631B1 (de) |
WO (1) | WO1988005785A1 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2610631B1 (fr) * | 1987-02-09 | 1989-11-24 | Pasteur Institut | Molecules comportant au moins une sequence peptidique porteuse d'un ou plusieurs, epitope caracteristique d'une proteine produite par p. falciparum dans les hepatocytes, et leurs utilisations, notamment pour le diagnostic du paludisme ou dans des compositions de vaccins contre le paludisme |
US6270771B1 (en) | 1988-10-06 | 2001-08-07 | Institut Pasteur | Peptide sequences specific for the hepatic stages of P. falciparum bearing epitopes capable of stimulating the T lymphocytes |
FR2672290B1 (fr) | 1991-02-05 | 1995-04-21 | Pasteur Institut | Sequences peptidiques specifiques des stades hepatiques de p. falciparum porteuses d'epitopes capables de stimuler les lymphocytes t. |
FR2656626B1 (fr) * | 1989-12-29 | 1994-08-12 | Pasteur Institut | Fragment peptidique comprenant une sequence issue de la proteine 28 kda de schistosoma mansoni et compositions vaccinantes et/ou therapeutiques comprenant ledit fragment. |
FR2665365B1 (fr) * | 1990-08-06 | 1995-04-28 | Pasteur Institut | Antigene de plasmodium falciparum susceptible d'induire des anticorps protecteurs - application a la vaccination. |
GB9020438D0 (en) * | 1990-09-19 | 1990-10-31 | Imperial College | Plasmodium liver stage antigens |
FR2697022B1 (fr) | 1992-10-19 | 1994-12-16 | Pasteur Institut | Antigènes de Plasmodium falciparum capables d'induire des anticorps protecteurs à large spectre - Application à la vaccination. |
US20030161840A1 (en) * | 1992-10-19 | 2003-08-28 | Institut Pasteur | Plasmodium falciparum antigens inducing protective antibodies |
GB0022017D0 (en) * | 2000-09-08 | 2000-10-25 | Univ Dundee | Cell assays |
EP1201250A1 (de) * | 2000-10-25 | 2002-05-02 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Immunogenische Zusammensetzung die hepatische Phaseantigene aus Plasmodium enthält |
EP2933334B1 (de) * | 2003-02-18 | 2019-09-18 | Baylor College of Medicine | Induzierte Aktivierung in dendritischen Zellen |
CA3058450A1 (en) * | 2006-10-19 | 2008-04-24 | Baylor College Of Medicine | Generating an immune response by inducing cd40 and pattern recognition receptors |
US20100203067A1 (en) | 2008-09-22 | 2010-08-12 | Baylor College Of Medicine | Methods and compositions for generating an immune response by inducing cd40 and pattern recognition receptor adapters |
WO2011146862A1 (en) | 2010-05-21 | 2011-11-24 | Bellicum Pharmaceuticals, Inc. | Methods for inducing selective apoptosis |
US9434935B2 (en) | 2013-03-10 | 2016-09-06 | Bellicum Pharmaceuticals, Inc. | Modified caspase polypeptides and uses thereof |
CN105209065B (zh) | 2013-03-14 | 2020-07-31 | 贝里坤制药股份有限公司 | 控制t细胞增殖的方法 |
EP3569253A1 (de) | 2013-06-05 | 2019-11-20 | Bellicum Pharmaceuticals, Inc. | Verfahren zur induktion von partieller apoptose mithilfe von caspasepolypeptiden |
EP3104866A4 (de) | 2014-02-14 | 2017-08-02 | Bellicum Pharmaceuticals, Inc. | Verfahren zur aktivierung von t-zellen mit einem induzierbaren chimären polypeptid |
AU2015312117A1 (en) | 2014-09-02 | 2017-03-02 | Bellicum Pharmaceuticals, Inc. | Costimulation of chimeric antigen receptors by Myd88 and CD40 polypeptides |
US10189880B2 (en) | 2014-11-03 | 2019-01-29 | Leiden University Medical Center | T cell receptors directed against Bob1 and uses thereof |
WO2016142783A2 (en) | 2015-03-10 | 2016-09-15 | Leiden University Medical Center | T-cell receptors directed against the preferentially expressed antigen of melanoma and uses thereof |
US20210147507A1 (en) | 2017-05-09 | 2021-05-20 | Bellicum Pharmaceuticals, Inc. | Methods to augment or alter signal transduction |
WO2019113509A2 (en) | 2017-12-08 | 2019-06-13 | Bellicum Pharmaceuticals, Inc. | Methods for enhancing and maintaining car-t cell efficacy |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU569722B2 (en) * | 1983-01-28 | 1988-02-18 | Saramane Pty Ltd | Expression of plasmodium falciparum polypeptides from cloned cdna |
AU584881B2 (en) * | 1984-02-21 | 1989-06-08 | British Technology Group Limited | Improvements in or relating to the production of malaria vaccines |
US4707357A (en) * | 1984-06-26 | 1987-11-17 | The United States Of America As Represented By The Secretary Of The Army | Immunologically active peptides capable of inducing immunization against malaria and genes encoding therefor |
FR2610631B1 (fr) * | 1987-02-09 | 1989-11-24 | Pasteur Institut | Molecules comportant au moins une sequence peptidique porteuse d'un ou plusieurs, epitope caracteristique d'une proteine produite par p. falciparum dans les hepatocytes, et leurs utilisations, notamment pour le diagnostic du paludisme ou dans des compositions de vaccins contre le paludisme |
AU4661889A (en) * | 1988-11-30 | 1990-06-26 | Biomedical Research Institute | A novel malarial sporozoite and exoerythrocytic peptide antigen |
US5139792A (en) * | 1990-07-19 | 1992-08-18 | Bio-Techniques Laboratories, Inc. | Method and system for dispensing live bacteria into animal feed and drinking water |
-
1987
- 1987-02-09 FR FR8701543A patent/FR2610631B1/fr not_active Expired
-
1988
- 1988-02-09 US US07/275,139 patent/US5599542A/en not_active Expired - Lifetime
- 1988-02-09 WO PCT/FR1988/000074 patent/WO1988005785A1/fr active IP Right Grant
- 1988-02-09 DE DE88901854T patent/DE3881204T2/de not_active Expired - Lifetime
- 1988-02-09 EP EP88901854A patent/EP0343186B1/de not_active Expired - Lifetime
- 1988-02-09 JP JP63501827A patent/JP2729070B2/ja not_active Expired - Lifetime
- 1988-02-09 AT AT88901854T patent/ATE89566T1/de not_active IP Right Cessation
- 1988-02-09 AU AU13428/88A patent/AU610571B2/en not_active Expired
-
1995
- 1995-06-05 US US08/462,062 patent/US5602031A/en not_active Expired - Lifetime
- 1995-06-05 US US08/463,512 patent/US5589343A/en not_active Expired - Lifetime
-
1996
- 1996-12-03 US US08/760,000 patent/US5928901A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5928901A (en) | 1999-07-27 |
DE3881204T2 (de) | 1993-11-11 |
EP0343186A1 (de) | 1989-11-29 |
US5599542A (en) | 1997-02-04 |
WO1988005785A1 (fr) | 1988-08-11 |
AU610571B2 (en) | 1991-05-23 |
JP2729070B2 (ja) | 1998-03-18 |
JPH01502194A (ja) | 1989-08-03 |
FR2610631B1 (fr) | 1989-11-24 |
FR2610631A1 (fr) | 1988-08-12 |
US5589343A (en) | 1996-12-31 |
DE3881204D1 (de) | 1993-06-24 |
EP0343186B1 (de) | 1993-05-19 |
US5602031A (en) | 1997-02-11 |
AU1342888A (en) | 1988-08-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
EELA | Cancelled due to lapse of time |