ATE8879T1 - Verfahren zur herstellung, abtrennung und reinigung dipeptidischer suessstoffe. - Google Patents

Verfahren zur herstellung, abtrennung und reinigung dipeptidischer suessstoffe.

Info

Publication number: ATE8879T1
Authority: AT; Austria
Prior art keywords: purification; processes; sweeteners; dipeptic; separation
Prior art date: 1981-09-08

Application number

AT82304608T

Other languages

English (en)

Inventor

Constantine Sklavounos

Original Assignee

Pfizer Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-09-08

Filing date

1982-09-02

Publication date

1984-08-15

1982-09-02 Application filed by Pfizer Inc. filed Critical Pfizer Inc.

1984-08-15 Application granted granted Critical

1984-08-15 Publication of ATE8879T1 publication Critical patent/ATE8879T1/de

Links

238000000034 method Methods 0.000 title abstract 3
235000003599 food sweetener Nutrition 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title abstract 2
238000000746 purification Methods 0.000 title abstract 2
239000003765 sweetening agent Substances 0.000 title abstract 2
238000000926 separation method Methods 0.000 title 1
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
150000001408 amides Chemical class 0.000 abstract 2
238000002425 crystallisation Methods 0.000 abstract 2
230000008025 crystallization Effects 0.000 abstract 2
KNIZBZYMVRWQKN-DMTCNVIQSA-N (3s)-3-amino-4-[[(2r)-1-amino-1-oxopropan-2-yl]amino]-4-oxobutanoic acid Chemical class NC(=O)[C@@H](C)NC(=O)[C@@H](N)CC(O)=O KNIZBZYMVRWQKN-DMTCNVIQSA-N 0.000 abstract 1
VMQCQYRHANDJBP-IUYQGCFVSA-N (3s)-3-amino-4-[[(2r)-1-amino-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid Chemical class OC(=O)C[C@H](N)C(=O)N[C@H](CO)C(N)=O VMQCQYRHANDJBP-IUYQGCFVSA-N 0.000 abstract 1
-1 Aromatic sulfonic acid salts Chemical class 0.000 abstract 1
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
108010016626 Dipeptides Proteins 0.000 abstract 1
238000002955 isolation Methods 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/801—Peptide sweetners

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Peptides Or Proteins (AREA)
Seasonings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Apparatus For Radiation Diagnosis (AREA)
Magnetic Resonance Imaging Apparatus (AREA)
Joints Allowing Movement (AREA)
Detergent Compositions (AREA)
Manufacturing Of Electrical Connectors (AREA)
Discharging, Photosensitive Material Shape In Electrophotography (AREA)
Coupling Device And Connection With Printed Circuit (AREA)

AT82304608T 1981-09-08 1982-09-02 Verfahren zur herstellung, abtrennung und reinigung dipeptidischer suessstoffe. ATE8879T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/300,366 US4375430A (en)	1981-09-08	1981-09-08	Processes for preparation, isolation and purification of dipeptide sweeteners
EP82304608A EP0074249B1 (de)	1981-09-08	1982-09-02	Verfahren zur Herstellung, Abtrennung und Reinigung dipeptidischer Süssstoffe

Publications (1)

Publication Number	Publication Date
ATE8879T1 true ATE8879T1 (de)	1984-08-15

Family

ID=23158792

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT82304608T ATE8879T1 (de)	1981-09-08	1982-09-02	Verfahren zur herstellung, abtrennung und reinigung dipeptidischer suessstoffe.

Country Status (19)

Country	Link
US (1)	US4375430A (de)
EP (1)	EP0074249B1 (de)
JP (1)	JPS5857350A (de)
AT (1)	ATE8879T1 (de)
AU (1)	AU534082B2 (de)
CA (1)	CA1238903A (de)
DE (1)	DE3260543D1 (de)
DK (1)	DK155947C (de)
ES (3)	ES8308304A1 (de)
FI (1)	FI76352C (de)
GR (1)	GR76704B (de)
IE (1)	IE53795B1 (de)
IL (1)	IL66739A (de)
MX (1)	MX155762A (de)
NO (1)	NO161123C (de)
NZ (1)	NZ201816A (de)
PT (1)	PT75519B (de)
YU (1)	YU43277B (de)
ZA (1)	ZA826522B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4855454A (en) *	1980-01-21	1989-08-08	Pfizer Inc.	Branched amides of L-aspartyl-D-amino acid dipeptides
US4465626A (en) *	1981-09-08	1984-08-14	Pfizer Inc.	Process for preparation, isolation and purification of dipeptide sweeteners
CA1276395C (en) *	1984-07-13	1990-11-13	John M. Janusz	Oxa-fenchyl esters and amides of alpha-l-aspartyl-d- phenylglycine
CA1276394C (en) *	1984-07-13	1990-11-13	John M. Janusz	Alpha-l-aspartyl-d-phenylglycine esters and amides useful as high intensity sweeteners
US4572799A (en) *	1985-04-15	1986-02-25	General Foods Corporation	L-Aminodicarboxylic acid amides
EP0199257A3 (de) *	1985-04-15	1988-08-10	General Foods Corporation	Ester von L-Aminodicarboxylsäure und eine geniessbare, sie als Süssstoff enthaltende Zusammensetzung
US4935355A (en) *	1986-04-15	1990-06-19	Synthetech, Inc.	Preparation of dipeptides
US4758443A (en) *	1986-06-18	1988-07-19	General Foods Corporation	Thietanyl-substituted amides and use thereof as sweeteners
US4855455A (en) *	1988-01-22	1989-08-08	W. R. Grace & Co.-Conn.	Preparation of amino acid derivatives
US5283357A (en) *	1988-03-14	1994-02-01	Mitsui Toatsu Chemicals, Incorporated	Separation method of α-l-aspartyl-l-phenylalanine methyl ester
ATE440092T1 (de) *	2004-10-14	2009-09-15	Wilex Ag	Verfahren zur reinigung von 3-hydroxy-amidino- phenylalanin-derivaten durch ausfällung und umkristallisation eines salzes mit einer aromatischen sulfonsäure

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA909254A (en) *	1969-12-30	1972-09-05	Ariyoshi Yasuo	METHOD OF PURIFYING LOWER ALKYL OF .alpha.-L-ASPARTYL-L-PHENYLALANINE

1981
- 1981-09-08 US US06/300,366 patent/US4375430A/en not_active Expired - Lifetime
1982
- 1982-09-02 AT AT82304608T patent/ATE8879T1/de active
- 1982-09-02 EP EP82304608A patent/EP0074249B1/de not_active Expired
- 1982-09-02 DE DE8282304608T patent/DE3260543D1/de not_active Expired
- 1982-09-03 CA CA000410725A patent/CA1238903A/en not_active Expired
- 1982-09-06 NO NO823002A patent/NO161123C/no not_active IP Right Cessation
- 1982-09-06 GR GR69210A patent/GR76704B/el unknown
- 1982-09-06 NZ NZ201816A patent/NZ201816A/en unknown
- 1982-09-06 FI FI823072A patent/FI76352C/fi not_active IP Right Cessation
- 1982-09-07 IL IL66739A patent/IL66739A/xx not_active IP Right Cessation
- 1982-09-07 YU YU2013/82A patent/YU43277B/xx unknown
- 1982-09-07 ZA ZA826522A patent/ZA826522B/xx unknown
- 1982-09-07 DK DK399182A patent/DK155947C/da not_active IP Right Cessation
- 1982-09-07 AU AU88087/82A patent/AU534082B2/en not_active Expired
- 1982-09-07 ES ES515545A patent/ES8308304A1/es not_active Expired
- 1982-09-07 IE IE2175/82A patent/IE53795B1/en not_active IP Right Cessation
- 1982-09-07 PT PT75519A patent/PT75519B/pt unknown
- 1982-09-07 MX MX194302A patent/MX155762A/es unknown
- 1982-09-08 JP JP57156505A patent/JPS5857350A/ja active Granted
1983
- 1983-04-22 ES ES521765A patent/ES521765A0/es active Granted
- 1983-04-22 ES ES521764A patent/ES8406063A1/es not_active Expired

Also Published As

Publication number	Publication date
PT75519A (en)	1982-10-01
JPS6318959B2 (de)	1988-04-20
IL66739A (en)	1985-07-31
CA1238903A (en)	1988-07-05
NO161123B (no)	1989-03-28
ES521764A0 (es)	1984-07-01
YU43277B (en)	1989-06-30
JPS5857350A (ja)	1983-04-05
ES8406064A1 (es)	1984-07-01
AU534082B2 (en)	1984-01-05
PT75519B (en)	1985-11-25
DK155947B (da)	1989-06-05
IL66739A0 (en)	1982-12-31
IE53795B1 (en)	1989-02-15
IE822175L (en)	1983-03-08
EP0074249A1 (de)	1983-03-16
US4375430A (en)	1983-03-01
FI76352B (fi)	1988-06-30
GR76704B (de)	1984-08-29
FI823072L (fi)	1983-03-09
FI823072A0 (fi)	1982-09-06
NO161123C (no)	1989-07-05
YU201382A (en)	1985-04-30
ES8406063A1 (es)	1984-07-01
NO823002L (no)	1983-03-09
FI76352C (fi)	1988-10-10
NZ201816A (en)	1985-05-31
ZA826522B (en)	1983-07-27
MX155762A (es)	1988-04-25
ES521765A0 (es)	1984-07-01
EP0074249B1 (de)	1984-08-08
DK155947C (da)	1989-11-13
ES515545A0 (es)	1983-08-16
DK399182A (da)	1983-03-09
AU8808782A (en)	1983-05-05
ES8308304A1 (es)	1983-08-16
DE3260543D1 (en)	1984-09-13

Publication	Publication Date	Title
DE3855056D1 (de)	1996-04-11	Verfahren zur Herstellung reiner primärer Diamine
ATE8879T1 (de)	1984-08-15	Verfahren zur herstellung, abtrennung und reinigung dipeptidischer suessstoffe.
DE3886800D1 (de)	1994-02-17	Verfahren zur Herstellung von Kautschuklaminaten.
DE3673637D1 (de)	1990-09-27	Verfahren zur gewinnung von organischen saeuren.
FR2658092B1 (fr)	1992-05-15	Procede de purification de solutions de polyorganophosphazene par membranes.
BE847153A (fr)	1977-04-12	Procede de preparation d'acide formique pur,
DK600483A (da)	1984-06-28	Fremgangsmaade til fremstilling af phosphonomethylerede aminosyrer
DE68923534D1 (de)	1995-08-24	Verfahren zur Herstellung eines organischen Kristalls.
DE69228648T2 (de)	1999-09-09	Verfahren zur Herstellung von komplementären, bipolaren Transistoren
DE69020804D1 (de)	1995-08-17	Verfahren zur Herstellung von Tauroursodesoxycholsäure Dihydrat.
DE3868875D1 (de)	1992-04-09	Apparat zur produktion von halbleitern.
ATE156129T1 (de)	1997-08-15	Verfahren zur herstellung von kristallisiertem loracarbef monohydrat
ATE116965T1 (de)	1995-01-15	Reinigungsprozess für n,n-diethylmandelsäureamid.
IT8822307A0 (it)	1988-10-14	Processo di lavorazione per membrana impermeabile bitume-polimero
DE3870737D1 (de)	1992-06-11	Verfahren zur herstellung von hochreiner weinsaeure.
ATE55984T1 (de)	1990-09-15	Verfahren zur herstellung von organischen diund polysulfiden.
ATE96170T1 (de)	1993-11-15	Verfahren zur herstellung von l-arginin.
ATE65091T1 (de)	1991-07-15	Kontinuierliches verfahren zur enzymatischen herstellung von isomaltulose.
DE68909725D1 (de)	1993-11-11	Verfahren zur Herstellung von Umkehrosmose-Membranen.
ATA905276A (de)	1977-12-15	Verfahren zur herstellung von bicyclo (2,2,2)oct-7-en-2,3,5,6-tetracarbonsaure-dianhydrid
ATE52077T1 (de)	1990-05-15	Katalystisches reduzierungsverfahren zur produktion von aromatischen aminoverbindungen.