ATE66477T1 - 2-guanidino-4-aryl-thiazole fuer die behandlung von peptischen geschwueren. - Google Patents

2-guanidino-4-aryl-thiazole fuer die behandlung von peptischen geschwueren.

Info

Publication number
ATE66477T1
ATE66477T1 AT87307495T AT87307495T ATE66477T1 AT E66477 T1 ATE66477 T1 AT E66477T1 AT 87307495 T AT87307495 T AT 87307495T AT 87307495 T AT87307495 T AT 87307495T AT E66477 T1 ATE66477 T1 AT E66477T1
Authority
AT
Austria
Prior art keywords
guanidino
treatment
optionally substituted
thiazole
aryl
Prior art date
Application number
AT87307495T
Other languages
English (en)
Inventor
John Lawrence Lamattina
Peter Andrew Mccarthy
Lawrence Alan Reiter
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE66477T1 publication Critical patent/ATE66477T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
AT87307495T 1986-08-29 1987-08-25 2-guanidino-4-aryl-thiazole fuer die behandlung von peptischen geschwueren. ATE66477T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8601795 1986-08-29
EP87307495A EP0259085B1 (de) 1986-08-29 1987-08-25 2-Guanidino-4-aryl-thiazole für die Behandlung von peptischen Geschwüren

Publications (1)

Publication Number Publication Date
ATE66477T1 true ATE66477T1 (de) 1991-09-15

Family

ID=22195621

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87307495T ATE66477T1 (de) 1986-08-29 1987-08-25 2-guanidino-4-aryl-thiazole fuer die behandlung von peptischen geschwueren.

Country Status (10)

Country Link
US (1) US5026715A (de)
EP (1) EP0259085B1 (de)
JP (1) JPH0633258B2 (de)
AT (1) ATE66477T1 (de)
DE (1) DE3772301D1 (de)
DK (1) DK451687A (de)
ES (1) ES2031514T3 (de)
GR (1) GR3002596T3 (de)
IE (1) IE60039B1 (de)
PT (1) PT85604B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6313156B1 (en) * 1999-12-23 2001-11-06 Icos Corporation Thiazole compounds as cyclic-AMP-specific phosphodiesterase inhibitors
DE102004008141A1 (de) * 2004-02-19 2005-09-01 Abbott Gmbh & Co. Kg Guanidinverbindungen und ihre Verwendung als Bindungspartner für 5-HT5-Rezeptoren
ES2402362T3 (es) 2004-09-30 2013-05-03 Takeda Pharmaceutical Company Limited Inhibidores de la bomba de protones
CA2621182C (en) 2005-08-30 2014-03-18 Takeda Pharmaceutical Company Limited 1-heterocyclylsulfonyl, 2-aminomethyl, 5-(hetero-)aryl substituted 1-h-pyrrole derivatives as acid secretion inhibitors
US7994205B2 (en) 2006-03-31 2011-08-09 Takeda Pharmaceutical Company Limited Aryl-or heteroaryl-sulfonyl compounds as acid secretion inhibitors
US8933105B2 (en) 2007-02-28 2015-01-13 Takeda Pharmaceutical Company Limited Pyrrole compounds
WO2010021149A1 (ja) * 2008-08-21 2010-02-25 武田薬品工業株式会社 酸分泌抑制スピロ化合物
NZ591793A (en) 2008-08-27 2012-11-30 Takeda Pharmaceutical Substituted 1-(4-fluoro-5-(2-fluoropyridin-3-yl)-1-((pyrindin-2-yl)sulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine compounds
WO2012172438A2 (en) * 2011-06-07 2012-12-20 Dynamix Pharmaceuticals Ltd. Compositions and methods for modulating a kinase

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3591584A (en) * 1968-08-27 1971-07-06 Pfizer Benzothiazine dioxides
CA963908A (en) * 1971-01-29 1975-03-04 David B. Capps Thiazolium salts
US3758491A (en) * 1972-01-07 1973-09-11 Parke Davis & Co Novel anti infective agents and means of producing the same
IE47458B1 (en) * 1977-11-07 1984-03-21 Leo Pharm Prod Ltd Quinolylguanidine derivatives
US4374843A (en) * 1980-10-14 1983-02-22 Pfizer Inc. 2-Guanidino-4-heteroarylthiazoles
US4435396A (en) * 1982-05-10 1984-03-06 Pfizer Inc. Antiulcer 2-guanidino-4-(2-substituted-amino-4-imidazolyl)thiazoles and process therefor
JPS59225186A (ja) * 1983-05-18 1984-12-18 Yamanouchi Pharmaceut Co Ltd 新規なグアニジノチアゾ−ル誘導体及びその製造方法
JPS59225172A (ja) * 1983-06-03 1984-12-18 Yamanouchi Pharmaceut Co Ltd 新規グアニジノチアゾ−ル誘導体及びその製法
US4560690A (en) * 1984-04-30 1985-12-24 Pfizer Inc. 2-(N-substituted guanidino)-4-hetero-arylthiazole antiulcer agents
US4791200A (en) * 1987-06-22 1988-12-13 Ortho Pharmaceutical Corporation 2-substituted-4-aryl-substituted thiazoles

Also Published As

Publication number Publication date
PT85604A (en) 1987-09-01
US5026715A (en) 1991-06-25
PT85604B (pt) 1990-05-31
GR3002596T3 (en) 1993-01-25
IE872277L (en) 1988-02-29
DK451687D0 (da) 1987-08-28
JPH0633258B2 (ja) 1994-05-02
EP0259085B1 (de) 1991-08-21
ES2031514T3 (es) 1992-12-16
IE60039B1 (en) 1994-05-18
DE3772301D1 (de) 1991-09-26
EP0259085A1 (de) 1988-03-09
DK451687A (da) 1988-05-13
JPS6363678A (ja) 1988-03-22

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee