ATE63747T1 - Antivirale verbindungen. - Google Patents

Antivirale verbindungen.

Info

Publication number: ATE63747T1
Authority: AT; Austria
Prior art keywords: antiviral compounds; ethynyluridine; deoxy; prophylaxis; processes
Prior art date: 1985-07-10

Application number

AT86305297T

Other languages

English (en)

Inventor

Saad George Rahim

John William Talbot Selway

Original Assignee

Wellcome Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-07-10

Filing date

1986-07-09

Publication date

1991-06-15

1986-07-09 Application filed by Wellcome Found filed Critical Wellcome Found

1991-06-15 Application granted granted Critical

1991-06-15 Publication of ATE63747T1 publication Critical patent/ATE63747T1/de

Links

150000001875 compounds Chemical class 0.000 title abstract 2
230000000840 anti-viral effect Effects 0.000 title 1
CDEURGJCGCHYFH-DJLDLDEBSA-N 5-ethynyl-2'-deoxyuridine Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(C#C)=C1 CDEURGJCGCHYFH-DJLDLDEBSA-N 0.000 abstract 1
206010011831 Cytomegalovirus infection Diseases 0.000 abstract 1
241000701085 Human alphaherpesvirus 3 Species 0.000 abstract 1
208000005181 Varicella Zoster Virus Infection Diseases 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1
208000010531 varicella zoster infection Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

AT86305297T 1985-07-10 1986-07-09 Antivirale verbindungen. ATE63747T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB858517402A GB8517402D0 (en)	1985-07-10	1985-07-10	Treatment of viral infections
EP86305297A EP0208550B1 (de)	1985-07-10	1986-07-09	Antivirale Verbindungen

Publications (1)

Publication Number	Publication Date
ATE63747T1 true ATE63747T1 (de)	1991-06-15

Family

ID=10582066

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86305297T ATE63747T1 (de)	1985-07-10	1986-07-09	Antivirale verbindungen.

Country Status (11)

Country	Link
US (1)	US4863906A (de)
EP (1)	EP0208550B1 (de)
JP (1)	JPS6212793A (de)
AT (1)	ATE63747T1 (de)
AU (1)	AU581329B2 (de)
DE (1)	DE3679353D1 (de)
DK (1)	DK326586A (de)
ES (1)	ES2000323A6 (de)
GB (1)	GB8517402D0 (de)
NZ (1)	NZ216798A (de)
ZA (1)	ZA865130B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8629892D0 (en)	1986-12-15	1987-01-28	Wellcome Found	Antiviral compounds
US5215971A (en) *	1986-12-19	1993-06-01	Medivir Ab	Antiviral pharmaceutical composition comprising 5-substituted pyrimidine nucleosides
US5215970A (en) *	1987-04-16	1993-06-01	Medivir Ab	Nucleosides and nucleotide analogues, pharmaceutical composition and processes for the preparation of the compounds
CA1340032C (en) *	1987-06-24	1998-09-08	Jim Haralambidis	Lucleoside derivatives
CA1301166C (en) *	1987-07-21	1992-05-19	John Nicholas Freskos	Process for preparing 2-deoxynucleosides
US5028596A (en) *	1987-12-14	1991-07-02	Burroughs Wellcome Co.	1-(β-D-arabinofuranosyl)-5-propynyluracil for treatment of VZV infections
EP0346108A3 (de) *	1988-06-09	1991-04-24	The Wellcome Foundation Limited	Anti-infektiöse Nukleoside
US5157114A (en) *	1988-08-19	1992-10-20	Burroughs Wellcome Co.	2',3'-dideoxy-3'-fluoro-5-ethyngluridine
HU207524B (en) *	1991-11-22	1993-04-28	Mta Koezponti Kemiai Kutato In	Industrial process for producing 5-alkyl-2'-deoxy-beta-uridines with stereoselective synthesis
CA2221279C (en) *	1995-06-02	2009-04-14	Nexstar Pharmaceuticals, Inc.	Palladium catalyzed nucleoside modification methods using nucleophiles and carbon monoxide
US20040067227A1 (en) *	2001-11-02	2004-04-08	Goldstein Allan L.	Inhibition or reversal of skin aging by actin-sequestering peptides
US20080096817A1 (en) *	1998-07-30	2008-04-24	Regenerx Biopharmaceuticals, Inc.	METHODS OF TREATING DISORDERS OF THE EYE AND SURROUNDING TISSUE WITH THYMOSIN BETA 4 (Tbeta4), ANALOGUES, ISOFORMS AND OTHER DERIVATIVES
PT1100529E (pt) *	1998-07-30	2005-10-31	Us Gov Health & Human Serv	A timosina beta 4 promove a preparacao de feridas
US6653318B1 (en)	1999-07-21	2003-11-25	Yale University	5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use
US6624096B2 (en) *	2001-08-20	2003-09-23	Cna Holdings, Inc.	Textile fabric for the outer shell of a firefighters's garmet
CA3103422A1 (en) *	2018-06-13	2019-12-19	Wilian Holding Company	Heavy duty spanning forms and related systems and methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1601020A (en) *	1978-04-24	1981-10-21	Stichting Grega Vzw	2'-deoxy-5 (2-halogenovinyl)-uridines
US4247544A (en) *	1979-07-02	1981-01-27	The Regents Of The University Of California	C-5 Substituted uracil nucleosides
HU183567B (en) *	1981-09-07	1984-05-28	Mta Koezponti Kemiai Kutato In	Process for preparing /e/-5-/2-bromo-vinyl/-uridine and derivatives thereof
EP0082668A1 (de) *	1981-12-18	1983-06-29	Beecham Group Plc	5-(2-Halogenvinyl)-2'-Deoxyuridinderivate, Verfahren zu ihrer Herstellung, die sie enthaltende pharmazeutische Präparate und ihre Verwendung bei der Bekämpfung von viralen Infektionen
US4782142A (en) *	1982-01-05	1988-11-01	The Research Foundation Of State University Of New York	Novel 5-substituted 2-pyrimidinone nucleosides and methods of use
US4594339A (en) *	1982-04-06	1986-06-10	Sloan-Kettering Institute For Cancer Research	Anti-herpes virus compositions containing 5-substituted 1-2'(deoxy-2-'-substituted-β-d-arabinofuranosyl)pyrimedene nucleosides
US4666777A (en)	1985-12-23	1987-05-19	The Dow Chemical Company	Structured latex core-shell polymer particles suitable for use in the preparation of composite sheets

1985
- 1985-07-10 GB GB858517402A patent/GB8517402D0/en active Pending
1986
- 1986-07-09 DK DK326586A patent/DK326586A/da not_active Application Discontinuation
- 1986-07-09 AT AT86305297T patent/ATE63747T1/de not_active IP Right Cessation
- 1986-07-09 JP JP61161748A patent/JPS6212793A/ja active Pending
- 1986-07-09 ES ES8600199A patent/ES2000323A6/es not_active Expired
- 1986-07-09 ZA ZA865130A patent/ZA865130B/xx unknown
- 1986-07-09 NZ NZ216798A patent/NZ216798A/xx unknown
- 1986-07-09 EP EP86305297A patent/EP0208550B1/de not_active Expired - Lifetime
- 1986-07-09 AU AU60055/86A patent/AU581329B2/en not_active Ceased
- 1986-07-09 DE DE8686305297T patent/DE3679353D1/de not_active Expired - Fee Related
- 1986-07-10 US US06/883,913 patent/US4863906A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AU6005586A (en)	1987-01-15
NZ216798A (en)	1990-02-26
GB8517402D0 (en)	1985-08-14
EP0208550A3 (en)	1988-04-20
DK326586A (da)	1987-01-11
ES2000323A6 (es)	1988-02-16
EP0208550B1 (de)	1991-05-22
DE3679353D1 (de)	1991-06-27
DK326586D0 (da)	1986-07-09
US4863906A (en)	1989-09-05
AU581329B2 (en)	1989-02-16
JPS6212793A (ja)	1987-01-21
ZA865130B (en)	1988-02-24
EP0208550A2 (de)	1987-01-14

Legal Events

Date	Code	Title	Description
1991-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ES2054693T3 (es)	1994-08-16	Compuestos antivirales.
NL300302I1 (nl)	2008-01-02	Antivirale verbindingen.
ATE63747T1 (de)	1991-06-15	Antivirale verbindungen.