ATE62484T1 - Pyrimidoisochinolinderivate. - Google Patents

Pyrimidoisochinolinderivate.

Info

Publication number
ATE62484T1
ATE62484T1 AT84308109T AT84308109T ATE62484T1 AT E62484 T1 ATE62484 T1 AT E62484T1 AT 84308109 T AT84308109 T AT 84308109T AT 84308109 T AT84308109 T AT 84308109T AT E62484 T1 ATE62484 T1 AT E62484T1
Authority
AT
Austria
Prior art keywords
pyrimidoisochinoline
derivatives
pyrimidoisochinoline derivatives
Prior art date
Application number
AT84308109T
Other languages
English (en)
Inventor
Ikuo Ueda
Youichi Shiokawa
Takashi Manabe
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838331228A external-priority patent/GB8331228D0/en
Priority claimed from GB848405776A external-priority patent/GB8405776D0/en
Priority claimed from GB848425791A external-priority patent/GB8425791D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Application granted granted Critical
Publication of ATE62484T1 publication Critical patent/ATE62484T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/08Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with a hetero atom directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT84308109T 1983-11-23 1984-11-22 Pyrimidoisochinolinderivate. ATE62484T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB838331228A GB8331228D0 (en) 1983-11-23 1983-11-23 Pyrimidoisoquinoline derivatives
GB848405776A GB8405776D0 (en) 1984-03-06 1984-03-06 Pyrimidoisoquinoline derivatives
GB848425791A GB8425791D0 (en) 1984-10-12 1984-10-12 Pyrimidoisoquinoline derivatives

Publications (1)

Publication Number Publication Date
ATE62484T1 true ATE62484T1 (de) 1991-04-15

Family

ID=27262222

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84308109T ATE62484T1 (de) 1983-11-23 1984-11-22 Pyrimidoisochinolinderivate.

Country Status (17)

Country Link
US (1) US4673676A (de)
EP (1) EP0143001B1 (de)
KR (2) KR920008168B1 (de)
AR (1) AR243889A1 (de)
AT (1) ATE62484T1 (de)
AU (1) AU582554B2 (de)
CA (1) CA1232605A (de)
DE (1) DE3484420D1 (de)
DK (1) DK165789C (de)
ES (2) ES537928A0 (de)
FI (1) FI77034C (de)
GR (1) GR81006B (de)
HU (1) HU202528B (de)
IL (1) IL73586A (de)
NO (1) NO162019C (de)
PH (1) PH22068A (de)
SU (1) SU1512482A3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO162019C (no) * 1983-11-23 1989-10-25 Fujisawa Pharmaceutical Co Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidoiskinolinderivater.
US4661592A (en) * 1984-06-27 1987-04-28 G. D. Searle & Co. 4H-pyrimido[2,1-a]isoquinolin-4-one derivatives
JP5406215B2 (ja) 2008-01-25 2014-02-05 ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー TNF−α合成の調節因子及びPDE4阻害剤としての三環系化合物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3876788A (en) * 1970-08-27 1975-04-08 Burroughs Wellcome Co Heterocyclic compounds in the treatment of inflammatory of arthritic conditions
US4017625A (en) * 1975-08-01 1977-04-12 Pfizer Inc. Anti-allergic N-(5-tetrazolyl)-1-oxo-1H-6-alkoxypyrimido-[1,2-a]quinoline-2-carboxamides and intermediates therefor
HU173438B (hu) * 1975-11-27 1979-05-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija novykh proizvodnykh 4-okso-1,6,7,8-/tetragidro-4h-pirido/1,2/pirimidina s zaderzhivajuhhejj vozgoranie aktivnot'ju i protivosvertivajuhhem effektom
US4127720A (en) * 1977-09-21 1978-11-28 Bristol-Myers Company Pyrimido[2,1-a]isoquinoline derivatives having antiallergy activity
IE51802B1 (en) * 1979-12-03 1987-04-01 Fujisawa Pharmaceutical Co Quinazoline derivatives,processes for their preparation and pharmaceutical compositions containing them
JPS59172490A (ja) * 1983-03-18 1984-09-29 Fujisawa Pharmaceut Co Ltd ピリミドイソキノリン誘導体およびその塩類、それらの製造法ならびにそれらを有効成分とする抗アレルギ−剤
JPS59172472A (ja) * 1983-03-18 1984-09-29 Fujisawa Pharmaceut Co Ltd イソキノリン誘導体およびその塩類、それらの製造法ならびにそれらを有効成分とする抗アレルギ−剤
NO162019C (no) * 1983-11-23 1989-10-25 Fujisawa Pharmaceutical Co Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidoiskinolinderivater.
US4661592A (en) * 1984-06-27 1987-04-28 G. D. Searle & Co. 4H-pyrimido[2,1-a]isoquinolin-4-one derivatives

Also Published As

Publication number Publication date
KR920001673B1 (ko) 1992-02-22
PH22068A (en) 1988-05-20
IL73586A (en) 1988-12-30
DK536184A (da) 1985-05-24
AU3540584A (en) 1985-05-30
KR920008168B1 (ko) 1992-09-24
ES8604220A1 (es) 1986-01-16
HUT35674A (en) 1985-07-29
FI844406A0 (fi) 1984-11-09
NO162019C (no) 1989-10-25
FI77034B (fi) 1988-09-30
NO162019B (no) 1989-07-17
US4673676A (en) 1987-06-16
FI77034C (fi) 1989-01-10
FI844406L (fi) 1985-05-24
KR850003538A (ko) 1985-06-20
DK536184D0 (da) 1984-11-09
AU582554B2 (en) 1989-04-06
IL73586A0 (en) 1985-02-28
DE3484420D1 (en) 1991-05-16
EP0143001B1 (de) 1991-04-10
EP0143001A2 (de) 1985-05-29
EP0143001A3 (en) 1986-03-19
ES8602786A1 (es) 1985-12-01
NO844466L (no) 1985-05-24
GR81006B (en) 1985-01-03
ES537928A0 (es) 1985-12-01
DK165789C (da) 1993-06-14
CA1232605A (en) 1988-02-09
AR243889A1 (es) 1993-09-30
ES546222A0 (es) 1986-01-16
SU1512482A3 (ru) 1989-09-30
DK165789B (da) 1993-01-18
HU202528B (en) 1991-03-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee