ATE59294T1 - Stabilisierte arzneimittel. - Google Patents

Stabilisierte arzneimittel.

Info

Publication number: ATE59294T1
Authority: AT; Austria
Prior art keywords: group; carbonate; stabilized; substituted; medications
Prior art date: 1986-10-13

Application number

AT87309038T

Other languages

English (en)

Inventor

Shozo Kouchiwa

Masami Nemoto

Tetsuo Yamaguchi

Atsuro Nakazato

Original Assignee

Taisho Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-10-13

Filing date

1987-10-13

Publication date

1991-01-15

1987-10-13 Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd

1991-01-15 Application granted granted Critical

1991-01-15 Publication of ATE59294T1 publication Critical patent/ATE59294T1/de

Links

229940079593 drug Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 abstract 2
CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 abstract 2
UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 abstract 2
YNGDWRXWKFWCJY-UHFFFAOYSA-N 1,4-Dihydropyridine Chemical class C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
239000012752 auxiliary agent Substances 0.000 abstract 1
229910000019 calcium carbonate Inorganic materials 0.000 abstract 1
235000010216 calcium carbonate Nutrition 0.000 abstract 1
FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 abstract 1
235000019700 dicalcium phosphate Nutrition 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
229910000030 sodium bicarbonate Inorganic materials 0.000 abstract 1
235000017557 sodium bicarbonate Nutrition 0.000 abstract 1
229910000029 sodium carbonate Inorganic materials 0.000 abstract 1
235000017550 sodium carbonate Nutrition 0.000 abstract 1
239000007787 solid Substances 0.000 abstract 1
239000003381 stabilizer Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Inorganic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

AT87309038T 1986-10-13 1987-10-13 Stabilisierte arzneimittel. ATE59294T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP61241299A JPS6396126A (ja)	1986-10-13	1986-10-13	安定化組成物
EP87309038A EP0264259B1 (de)	1986-10-13	1987-10-13	Stabilisierte Arzneimittel

Publications (1)

Publication Number	Publication Date
ATE59294T1 true ATE59294T1 (de)	1991-01-15

Family

ID=17072213

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT87309038T ATE59294T1 (de)	1986-10-13	1987-10-13	Stabilisierte arzneimittel.

Country Status (6)

Country	Link
US (1)	US4906647A (de)
EP (1)	EP0264259B1 (de)
JP (1)	JPS6396126A (de)
KR (1)	KR880004809A (de)
AT (1)	ATE59294T1 (de)
DE (1)	DE3767114D1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4929605A (en) *	1987-10-07	1990-05-29	Merrell Dow Pharmaceuticals Inc.	Pharmaceutical composition for piperidinoalkanol derivatives
AR240018A1 (es) *	1987-10-07	1990-01-31	Merrell Pharma Inc	Procedimiento para preparar una composicion que comprende derivados de piperidinoalcanol.
US5886012A (en) *	1989-03-22	1999-03-23	Peter K. T. Pang	Method of treatment for disease associated with excessive PHF using combination therapy involving exogenous calcium and calcium channel blockers
US5350771A (en) *	1989-03-22	1994-09-27	Peter K. T. Pang	Method and treatment for hypertension using combination therapy involving exogenous calcium and calcium channel blockers
WO1990011074A1 (en) *	1989-03-22	1990-10-04	Pang Peter K T	Parathyroid hypertensive factor
CA2035841C (en) *	1990-02-22	1996-02-13	Harry B. Demopoulos	Storage-stable glucosamine sulphate oral dosage forms and methods for their manufacture
BE1011045A3 (fr) *	1997-03-14	1999-04-06	Ucb Sa	Compositions pharmaceutiques pour la liberation controlee de substances actives.
WO2001045668A2 (en) *	1999-12-20	2001-06-28	Schering Corporation	Stable extended release oral dosage composition comprising pseudoephedrine and desloratadine
AU2276801A (en)	1999-12-20	2001-07-03	Schering Corporation	Extended release oral dosage composition
US7405223B2 (en)	2000-02-03	2008-07-29	Schering Corporation	Treating allergic and inflammatory conditions
KR100756565B1 (ko) *	2000-04-11	2007-09-07	상꾜 가부시키가이샤	칼슘 채널 블록커를 함유하는 안정화된 약제 조성물
US20030235628A1 (en) *	2001-09-19	2003-12-25	Rajneesh Taneja	Methods and pharmaceutical formulations for protecting pharmaceutical compounds from acidic environments
TW200806648A (en) *	2005-11-29	2008-02-01	Sankyo Co	Acid addition salts of dihydropyridine derivatives
TW200736245A (en) *	2005-11-29	2007-10-01	Sankyo Co	Acid addition salts of optically active dihydropyridine derivatives
ES2728776T3 (es)	2009-05-19	2019-10-28	Celgene Corp	Formulaciones de 4-amino-2-(2,6-dioxopiperidin-3-il)isoindolin-1,3-diona

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5547608A (en) *	1978-09-27	1980-04-04	Key Pharma	Skin medicine
JPS56139414A (en) *	1980-04-01	1981-10-30	Dai Ichi Seiyaku Co Ltd	Stabilizing method of aqueous solution
DE3212736A1 (de) *	1982-04-06	1983-10-13	Bayer Ag, 5090 Leverkusen	Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung
JPS58185562A (ja) *	1982-04-22	1983-10-29	Taisho Pharmaceut Co Ltd	１，４−ジヒドロピリジン誘導体
JPS58201726A (ja) *	1982-05-18	1983-11-24	Meiji Seika Kaisha Ltd	安定な製剤の製造法
JPS6089420A (ja) *	1983-10-21	1985-05-20	Taisho Pharmaceut Co Ltd	血管拡張剤
NL8400911A (nl) *	1984-03-22	1985-10-16	Dagra Nv	Werkwijze ter bereiding van een farmaceutische toedieningsvorm die tetracycline of doxycyclinezouten bevat.
DE3419128A1 (de) *	1984-05-23	1985-11-28	Bayer Ag, 5090 Leverkusen	Dihydropyridinpraeparate und verfahren zu ihrer herstellung
DE3419131A1 (de) *	1984-05-23	1985-11-28	Bayer Ag, 5090 Leverkusen	Dihydropyridinkombinationspraeparate und verfahren zu ihrer herstellung
US4730052A (en) *	1984-07-13	1988-03-08	Taisho Pharmaceutical Co., Ltd.	Method for preparing unsymmetrical 1,4-dihydropyridine-3,5-dicarboxylic acid diesters

1986
- 1986-10-13 JP JP61241299A patent/JPS6396126A/ja active Pending
1987
- 1987-10-01 US US07/103,297 patent/US4906647A/en not_active Expired - Fee Related
- 1987-10-12 KR KR870011258A patent/KR880004809A/ko not_active Application Discontinuation
- 1987-10-13 DE DE8787309038T patent/DE3767114D1/de not_active Expired - Lifetime
- 1987-10-13 AT AT87309038T patent/ATE59294T1/de not_active IP Right Cessation
- 1987-10-13 EP EP87309038A patent/EP0264259B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
KR880004809A (ko)	1988-06-27
EP0264259B1 (de)	1990-12-27
JPS6396126A (ja)	1988-04-27
DE3767114D1 (de)	1991-02-07
EP0264259A1 (de)	1988-04-20
US4906647A (en)	1990-03-06

Legal Events

Date	Code	Title	Description
1991-06-15	UEP	Publication of translation of european patent specification
1996-07-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
KR870700620A (ko)	1987-12-30	신규 약리학적 화합물
FI890689A (fi)	1989-08-23	3-alkenyl-1-azabicyklo-/3.2.0/ -hept-2-en-2-karboxylsyrafoereningar.
ATE81975T1 (de)	1992-11-15	Arzneimittel mit psychotroper wirkung.
ATE59294T1 (de)	1991-01-15	Stabilisierte arzneimittel.
SE8804629D0 (sv)	1988-12-22	New therapeutically active compounds
DK324185D0 (da)	1985-07-17	2-substituerede 1,3-propylidendiphosphonatderivater, deres fremstilling og farmaceutiske praeparater med indhold deraf
SE8404065D0 (sv)	1984-08-10	Novel biologically active compounds
SE8600658D0 (sv)	1986-02-14	Novel composition of matter
ZA872664B (en)	1988-01-14	Six-membered heterocyclic derivatives of n'-substituted-n,n'-diacylhydrazines
IE870845L (en)	1988-03-26	N'-substituted-n,n'-diacylhydrazines
DK52685A (da)	1985-09-20	N,3-diacyl-2-oxindol-1-carboxamid-forbindelser og mellemprodukter ved deres fremstilling samt farmaceutisk praeparat
DK434789A (da)	1990-03-03	3-piperidinyl-indazolderivater, fremgangsmaade til fremstilling deraf samt praeparater indeholdende samme
IL83216A (en)	1991-07-18	1((5-(10->9)abeo-6-methylergolin-8beta-yl)methyl)-imidazolidine-(and hexahydropyrimidine)-2,4-dione derivatives,their preparation and pharmaceutical compositions containing them
DK0578535T3 (da)	1996-12-09	Hidtil ukendt peptid-derivater, der er aktive i celleadhæsionsprocesser, fremgangsmåde til deres fremstilling samt farmaceutiske sammensætninger indeholdende derivarerne
KR860002498A (ko)	1986-04-26	1,4-디하이드로피리딘 유도체의 약학조성물
IT1224404B (it)	1990-10-04	Composti attivi sul sistema cardiovascolare