ATE553211T1 - Nachweis von nukleinsäuren über amplifikation von stellvertreternukleinsäuren - Google Patents
Nachweis von nukleinsäuren über amplifikation von stellvertreternukleinsäurenInfo
- Publication number
- ATE553211T1 ATE553211T1 AT06837254T AT06837254T ATE553211T1 AT E553211 T1 ATE553211 T1 AT E553211T1 AT 06837254 T AT06837254 T AT 06837254T AT 06837254 T AT06837254 T AT 06837254T AT E553211 T1 ATE553211 T1 AT E553211T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acids
- deputy
- detection
- via amplification
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73580805P | 2005-11-10 | 2005-11-10 | |
| PCT/US2006/043659 WO2007058898A2 (en) | 2005-11-10 | 2006-11-09 | Detection of nucleic acids through amplification of surrogate nucleic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE553211T1 true ATE553211T1 (de) | 2012-04-15 |
Family
ID=38049149
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06837254T ATE553211T1 (de) | 2005-11-10 | 2006-11-09 | Nachweis von nukleinsäuren über amplifikation von stellvertreternukleinsäuren |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8017360B2 (de) |
| EP (1) | EP1951905B1 (de) |
| AT (1) | ATE553211T1 (de) |
| CA (1) | CA2627967A1 (de) |
| WO (1) | WO2007058898A2 (de) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070166741A1 (en) | 1998-12-14 | 2007-07-19 | Somalogic, Incorporated | Multiplexed analyses of test samples |
| CA2606723A1 (en) * | 2005-05-09 | 2006-11-16 | Panomics, Inc. | Multiplex capture of nucleic acids |
| US8632970B2 (en) | 2005-05-09 | 2014-01-21 | Affymetrix, Inc. | Multiplex capture of nucleic acids |
| EP1880025B1 (de) * | 2005-05-12 | 2011-03-16 | Affymetrix, Inc. | Multiplex-assays für verzweigtkettige dna |
| ES2565670T3 (es) * | 2005-06-20 | 2016-04-06 | Advanced Cell Diagnostics, Inc. | Métodos de detección de ácidos nucleicos en células individuales y de identificación de células raras en grandes poblaciones de células heterogéneas |
| US20090081688A1 (en) * | 2005-06-20 | 2009-03-26 | Advanced Cell Diagnostics | Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations |
| US20110136099A1 (en) | 2007-01-16 | 2011-06-09 | Somalogic, Inc. | Multiplexed Analyses of Test Samples |
| EP2511708B1 (de) | 2007-10-05 | 2016-09-14 | Affymetrix, Inc. | Assays auf der Basis hoch gebündelter Partikel |
| US8180572B2 (en) * | 2007-10-25 | 2012-05-15 | Canon U.S. Life Sciences, Inc. | High-resolution melting analysis |
| US20090298709A1 (en) * | 2008-05-28 | 2009-12-03 | Affymetrix, Inc. | Assays for determining telomere length and repeated sequence copy number |
| US8691504B2 (en) * | 2009-05-26 | 2014-04-08 | Xiamen University | Method for detecting variations in nucleic acid sequences |
| US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| US20190300945A1 (en) | 2010-04-05 | 2019-10-03 | Prognosys Biosciences, Inc. | Spatially Encoded Biological Assays |
| CN104849472A (zh) | 2010-10-21 | 2015-08-19 | 领先细胞医疗诊断有限公司 | 用于原位检测核酸的超灵敏方法 |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| EP2744916A4 (de) | 2011-07-13 | 2015-06-17 | Primeradx Inc | Multimodale verfahren zur simultanen erkennung und quantifizierung mehrerer nukleinsäuren in einer probe |
| US9783841B2 (en) | 2012-10-04 | 2017-10-10 | The Board Of Trustees Of The Leland Stanford Junior University | Detection of target nucleic acids in a cellular sample |
| US9273349B2 (en) | 2013-03-14 | 2016-03-01 | Affymetrix, Inc. | Detection of nucleic acids |
| CN105849275B (zh) | 2013-06-25 | 2020-03-17 | 普罗格诺西斯生物科学公司 | 检测样品中生物靶标的空间分布的方法和*** |
| CN106661606B (zh) | 2014-06-13 | 2021-12-21 | Q-莱纳公司 | 用于检测和表征微生物的方法 |
| EP3530752B1 (de) | 2015-04-10 | 2021-03-24 | Spatial Transcriptomics AB | Räumlich getrennte multiplex-nukleinsäureanalyse von biologischen proben |
| GB201507026D0 (en) | 2015-04-24 | 2015-06-10 | Linea Ab Q | Medical sample transportation container |
| US10478261B2 (en) * | 2015-05-29 | 2019-11-19 | Deka Products Limited Partnership | System, method, and apparatus for remote patient care |
| ES2893100T3 (es) | 2015-10-12 | 2022-02-08 | Advanced Cell Diagnostics Inc | Detección in situ de variantes de nucleótidos en muestras con un elevado nivel de ruido, y composiciones y métodos relacionados con ésta |
| GB2554767A (en) | 2016-04-21 | 2018-04-11 | Q Linea Ab | Detecting and characterising a microorganism |
| CN110225980B (zh) | 2016-11-21 | 2023-01-06 | 纳米线科技公司 | 化学组合物及其使用方法 |
| CA3099909A1 (en) | 2018-05-14 | 2019-11-21 | Nanostring Technologies, Inc. | Chemical compositions and methods of using same |
| US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
| EP3894585A2 (de) | 2018-12-10 | 2021-10-20 | 10X Genomics, Inc. | Erzeugung von erfassungssonden zur räumlichen analyse |
| US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| EP3976820A1 (de) | 2019-05-30 | 2022-04-06 | 10X Genomics, Inc. | Verfahren zum nachweis der räumlichen heterogenität einer biologischen probe |
| EP4025711A2 (de) | 2019-11-08 | 2022-07-13 | 10X Genomics, Inc. | Erhöhung der spezifität einer analytbindung |
| SG11202106899SA (en) | 2019-12-23 | 2021-09-29 | 10X Genomics Inc | Methods for spatial analysis using rna-templated ligation |
| US11702693B2 (en) | 2020-01-21 | 2023-07-18 | 10X Genomics, Inc. | Methods for printing cells and generating arrays of barcoded cells |
| US11732299B2 (en) | 2020-01-21 | 2023-08-22 | 10X Genomics, Inc. | Spatial assays with perturbed cells |
| US11898205B2 (en) | 2020-02-03 | 2024-02-13 | 10X Genomics, Inc. | Increasing capture efficiency of spatial assays |
| US11732300B2 (en) | 2020-02-05 | 2023-08-22 | 10X Genomics, Inc. | Increasing efficiency of spatial analysis in a biological sample |
| US11891654B2 (en) | 2020-02-24 | 2024-02-06 | 10X Genomics, Inc. | Methods of making gene expression libraries |
| EP4242325A3 (de) | 2020-04-22 | 2023-10-04 | 10X Genomics, Inc. | Verfahren zur räumlichen analyse unter verwendung von gezieltem rna-abbau |
| EP4153776A1 (de) | 2020-05-22 | 2023-03-29 | 10X Genomics, Inc. | Räumliche analyse zur erkennung von sequenzvarianten |
| EP4153775A1 (de) | 2020-05-22 | 2023-03-29 | 10X Genomics, Inc. | Simultane räumlich-zeitliche messung der genexpression und der zellaktivität |
| WO2021242834A1 (en) | 2020-05-26 | 2021-12-02 | 10X Genomics, Inc. | Method for resetting an array |
| WO2021252499A1 (en) | 2020-06-08 | 2021-12-16 | 10X Genomics, Inc. | Methods of determining a surgical margin and methods of use thereof |
| EP4165207A1 (de) * | 2020-06-10 | 2023-04-19 | 10X Genomics, Inc. | Verfahren zur bestimmung einer position eines analyten in einer biologischen probe |
| AU2021294334A1 (en) | 2020-06-25 | 2023-02-02 | 10X Genomics, Inc. | Spatial analysis of DNA methylation |
| US11761038B1 (en) | 2020-07-06 | 2023-09-19 | 10X Genomics, Inc. | Methods for identifying a location of an RNA in a biological sample |
| US11981960B1 (en) | 2020-07-06 | 2024-05-14 | 10X Genomics, Inc. | Spatial analysis utilizing degradable hydrogels |
| US11981958B1 (en) | 2020-08-20 | 2024-05-14 | 10X Genomics, Inc. | Methods for spatial analysis using DNA capture |
| US11926822B1 (en) | 2020-09-23 | 2024-03-12 | 10X Genomics, Inc. | Three-dimensional spatial analysis |
| US11827935B1 (en) | 2020-11-19 | 2023-11-28 | 10X Genomics, Inc. | Methods for spatial analysis using rolling circle amplification and detection probes |
| AU2021409136A1 (en) | 2020-12-21 | 2023-06-29 | 10X Genomics, Inc. | Methods, compositions, and systems for capturing probes and/or barcodes |
| WO2023034489A1 (en) | 2021-09-01 | 2023-03-09 | 10X Genomics, Inc. | Methods, compositions, and kits for blocking a capture probe on a spatial array |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5093232A (en) | 1985-12-11 | 1992-03-03 | Chiron Corporation | Nucleic acid probes |
| US4868105A (en) | 1985-12-11 | 1989-09-19 | Chiron Corporation | Solution phase nucleic acid sandwich assay |
| US5124246A (en) | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
| US5849481A (en) | 1990-07-27 | 1998-12-15 | Chiron Corporation | Nucleic acid hybridization assays employing large comb-type branched polynucleotides |
| US6037120A (en) | 1995-10-12 | 2000-03-14 | Benner; Steven Albert | Recognition of oligonucleotides containing non-standard base pairs |
| US6140496A (en) | 1990-10-09 | 2000-10-31 | Benner; Steven Albert | Precursors for deoxyribonucleotides containing non-standard nucleosides |
| US5432272A (en) | 1990-10-09 | 1995-07-11 | Benner; Steven A. | Method for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heterocyclic bases |
| US5747244A (en) | 1991-12-23 | 1998-05-05 | Chiron Corporation | Nucleic acid probes immobilized on polystyrene surfaces |
| WO1994000598A1 (en) | 1992-06-19 | 1994-01-06 | Northwestern University | Method of detecting amplified nucleic acid sequences in cells by flow cytometry |
| US5681697A (en) | 1993-12-08 | 1997-10-28 | Chiron Corporation | Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor |
| US5681702A (en) | 1994-08-30 | 1997-10-28 | Chiron Corporation | Reduction of nonspecific hybridization by using novel base-pairing schemes |
| JP4040087B2 (ja) | 1995-05-05 | 2008-01-30 | アプレラ コーポレイション | Ｐｃｒ増幅とハイブリダイゼーションプロービングアッセイとを組み合わせた方法およびそのための試薬 |
| US5780227A (en) | 1995-06-07 | 1998-07-14 | Sheridan; Patrick J. | Oligonucleotide probe conjugated to a purified hydrophilic alkaline phosphatase and uses thereof |
| US5981180A (en) | 1995-10-11 | 1999-11-09 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and methods |
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| US5866336A (en) | 1996-07-16 | 1999-02-02 | Oncor, Inc. | Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon |
| US20020172953A1 (en) | 1996-07-29 | 2002-11-21 | Mirkin Chad A. | Movement of biomolecule-coated nanoparticles in an electric field |
| US6449562B1 (en) | 1996-10-10 | 2002-09-10 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and method |
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| US20040161741A1 (en) * | 2001-06-30 | 2004-08-19 | Elazar Rabani | Novel compositions and processes for analyte detection, quantification and amplification |
| US20040115686A1 (en) | 2002-05-17 | 2004-06-17 | Douglas Dolginow | Materials and methods to detect alternative splicing of mrna |
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| CA2606723A1 (en) | 2005-05-09 | 2006-11-16 | Panomics, Inc. | Multiplex capture of nucleic acids |
| EP1880025B1 (de) | 2005-05-12 | 2011-03-16 | Affymetrix, Inc. | Multiplex-assays für verzweigtkettige dna |
| US20090081688A1 (en) | 2005-06-20 | 2009-03-26 | Advanced Cell Diagnostics | Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations |
| ES2565670T3 (es) | 2005-06-20 | 2016-04-06 | Advanced Cell Diagnostics, Inc. | Métodos de detección de ácidos nucleicos en células individuales y de identificación de células raras en grandes poblaciones de células heterogéneas |
| WO2007044427A2 (en) | 2005-10-05 | 2007-04-19 | Panomics, Inc. | Detection of nucleic acids from whole blood |
| JP2008043332A (ja) | 2006-08-17 | 2008-02-28 | Panomics Inc | 組織スライドからの核酸定量 |
| US7615351B2 (en) | 2006-12-01 | 2009-11-10 | Panomics, Inc. | Two stage nucleic acid amplification using an amplification oligomer |
-
2006
- 2006-11-09 AT AT06837254T patent/ATE553211T1/de active
- 2006-11-09 EP EP06837254A patent/EP1951905B1/de active Active
- 2006-11-09 CA CA002627967A patent/CA2627967A1/en not_active Abandoned
- 2006-11-09 WO PCT/US2006/043659 patent/WO2007058898A2/en active Application Filing
- 2006-11-09 US US11/595,789 patent/US8017360B2/en active Active
-
2011
- 2011-08-10 US US13/207,237 patent/US8288522B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20120009577A1 (en) | 2012-01-12 |
| US8288522B2 (en) | 2012-10-16 |
| EP1951905A2 (de) | 2008-08-06 |
| EP1951905B1 (de) | 2012-04-11 |
| CA2627967A1 (en) | 2007-05-24 |
| US20070161020A1 (en) | 2007-07-12 |
| WO2007058898A2 (en) | 2007-05-24 |
| WO2007058898A3 (en) | 2007-11-15 |
| EP1951905A4 (de) | 2009-05-06 |
| US8017360B2 (en) | 2011-09-13 |
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